Standard name Systematic name Name description Description
PIK1 YNL267W Phosphatidylinositol 4-kinase Phosphatidylinositol 4-kinase; catalyzes the first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton; required for autophagosome formation during autophagy and for lipophagy in both stationary phase cells and during nitrogen starvation; may control nonselective autophagy and mitophagy through trafficking of Atg9p; localizes to the nucleus and to the trans-Golgi network
Visualize the interactome of PIK1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.972 0.962 0.995
Mito NaN 0.058 NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 1600

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PIK1 5 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_2836 (phosphatidylinositol 4-kinase (1-16:0, 2-16:1), Golgi membrane), r_2842 (phosphatidylinositol 4-kinase (1-18:0, 2-18:1), Golgi membrane), r_2848 (phosphatidylinositol 4-kinase (1-16:0, 2-18:1), nucleus), r_2839 (phosphatidylinositol 4-kinase (1-18:1, 2-16:1), Golgi membrane), r_2845 (phosphatidylinositol 4-kinase (1-16:1, 2-16:1), nucleus), r_2851 (phosphatidylinositol 4-kinase (1-18:1, 2-18:1), nucleus), r_2849 (phosphatidylinositol 4-kinase (1-16:1, 2-18:1), nucleus), r_2837 (phosphatidylinositol 4-kinase (1-16:1, 2-16:1), Golgi membrane), r_2846 (phosphatidylinositol 4-kinase (1-18:0, 2-16:1), nucleus), r_2843 (phosphatidylinositol 4-kinase (1-18:1, 2-18:1), Golgi membrane), r_2840 (phosphatidylinositol 4-kinase (1-16:0, 2-18:1), Golgi membrane), r_2844 (phosphatidylinositol 4-kinase (1-16:0, 2-16:1), nucleus), r_2838 (phosphatidylinositol 4-kinase (1-18:0, 2-16:1), Golgi membrane), r_2850 (phosphatidylinositol 4-kinase (1-18:0, 2-18:1), nucleus), r_2841 (phosphatidylinositol 4-kinase (1-16:1, 2-18:1), Golgi membrane), r_2847 (phosphatidylinositol 4-kinase (1-18:1, 2-16:1), nucleus)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FRQ1 YDR373W N-myristoylated calcium-binding protein physical 12 5 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
BMH2 YDR099W 14-3-3 protein, minor isoform physical 7 5 3 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western
BMH1 YER177W 14-3-3 protein, major isoform physical 6 5 1 Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-fractionation
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 5 3 3 Dosage Rescue, Dosage Rescue, Negative Genetic, Synthetic Rescue, Synthetic Rescue
PKR1 YMR123W V-ATPase assembly factor genetic 4 3 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking physical 4 3 2 Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Co-localization
YPT31 YER031C Rab family GTPase genetic 4 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Phenotypic Enhancement
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 3 2 3 Phenotypic Enhancement, Synthetic Lethality, Phenotypic Enhancement
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 3 3 2 Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 3 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 3 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 3 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 3 3 1 Two-hybrid, Reconstituted Complex, Affinity Capture-Western
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 2 2 2 Synthetic Lethality, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 2 2 2 Synthetic Lethality, Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 2 2 2 Synthetic Lethality, Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 2 2 2 Synthetic Lethality, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
PFY1 YOR122C Profilin genetic 2 2 2 Synthetic Lethality, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 2 2 Synthetic Lethality, Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 2 2 2 Synthetic Lethality, Negative Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 2 2 2 Synthetic Lethality, Dosage Rescue
SEC4 YFL005W Rab family GTPase genetic 2 2 2 Synthetic Lethality, Dosage Rescue
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 2 2 Positive Genetic, Synthetic Lethality
SYS1 YJL004C Integral membrane protein of the Golgi genetic 2 2 2 Synthetic Lethality, Negative Genetic
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 2 2 2 Synthetic Lethality, Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 2 2 2 Synthetic Lethality, Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 2 2 2 Synthetic Lethality, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 2 1 2 Positive Genetic, Positive Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 2 1 2 Dosage Rescue, Dosage Rescue
TED1 YIL039W GPI-glycan remodelase genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YPT6 YLR262C Rab family GTPase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TCA17 YEL048C Component of transport protein particle (TRAPP) complex II genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Lethality
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Dosage Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Dosage Rescue
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Dosage Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Synthetic Growth Defect
ATP11 YNL315C Molecular chaperone genetic 1 1 1 Synthetic Growth Defect
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) physical 1 1 1 Two-hybrid
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MRP10 YDL045W-A Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
MLC1 YGL106W Essential light chain for Myo1p physical 1 1 1 Two-hybrid
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Synthetic Growth Defect
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Synthetic Growth Defect
BLM10 YFL007W Proteasome activator genetic 1 1 1 Synthetic Growth Defect
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
MRPL38 YKL170W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
MIR1 YJR077C Mitochondrial phosphate carrier genetic 1 1 1 Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Negative Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Synthetic Growth Defect
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
CNB1 YKL190W Calcineurin B genetic 1 1 1 Synthetic Growth Defect
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p genetic 1 1 1 Synthetic Growth Defect
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity physical 1 1 1 Affinity Capture-MS
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 1 1 1 Phenotypic Suppression
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Synthetic Growth Defect
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Lethality
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
MTF1 YMR228W Mitochondrial RNA polymerase specificity factor genetic 1 1 1 Synthetic Growth Defect
AIM18 YHR198C Protein of unknown function genetic 1 1 1 Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Dosage Rescue
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
MKC7 YDR144C GPI-anchored aspartyl protease genetic 1 1 1 Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Negative Genetic
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Synthetic Lethality
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Synthetic Lethality
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Lethality
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
FUS1 YCL027W Membrane protein localized to the shmoo tip physical 1 1 1 Two-hybrid
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Synthetic Growth Defect
MLS1 YNL117W Malate synthase, enzyme of the glyoxylate cycle genetic 1 1 1 Synthetic Lethality
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Negative Genetic
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Negative Genetic
DAL5 YJR152W Allantoate permease genetic 1 1 1 Negative Genetic
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Negative Genetic
GID11 YLR149C Substrate receptor of the glucose-induced degradation-deficient (GID) genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Synthetic Growth Defect
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Synthetic Growth Defect
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Phenotypic Enhancement
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
IPT1 YDR072C Inositolphosphotransferase genetic 1 1 1 Negative Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Synthetic Lethality
OPY2 YPR075C Integral membrane protein that acts as a membrane anchor for Ste50p genetic 1 1 1 Phenotypic Suppression
ALR2 YFL050C Probable Mg(2+) transporter genetic 1 1 1 Synthetic Growth Defect
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Synthetic Growth Defect
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Synthetic Growth Defect
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Synthetic Growth Defect
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Synthetic Lethality
SEC3 YER008C Subunit of the exocyst complex genetic 1 1 1 Synthetic Growth Defect
SEC5 YDR166C Essential 107kDa subunit of the exocyst complex genetic 1 1 1 Synthetic Lethality
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex genetic 1 1 1 Synthetic Lethality
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 1 1 1 Synthetic Lethality
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex genetic 1 1 1 Synthetic Growth Defect
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Phenotypic Suppression
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Synthetic Lethality
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Synthetic Lethality
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Synthetic Growth Defect
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Synthetic Growth Defect
VPS28 YPL065W Component of the ESCRT-I complex genetic 1 1 1 Phenotypic Enhancement
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPL12A YEL054C Ribosomal 60S subunit protein L12A genetic 1 1 1 Synthetic Growth Defect
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A genetic 1 1 1 Synthetic Growth Defect
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 1 1 1 Synthetic Growth Defect
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Synthetic Growth Defect
RPL1B YGL135W Ribosomal 60S subunit protein L1B genetic 1 1 1 Synthetic Growth Defect
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 genetic 1 1 1 Synthetic Growth Defect
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Synthetic Growth Defect
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Synthetic Growth Defect
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Synthetic Growth Defect
SOV1 YMR066W Mitochondrial protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Synthetic Growth Defect
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Synthetic Growth Defect
TRM9 YML014W tRNA methyltransferase genetic 1 1 1 Synthetic Growth Defect
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Synthetic Growth Defect
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
SMF1 YOL122C Divalent metal ion transporter genetic 1 1 1 Synthetic Growth Defect
TIP41 YPR040W Tap42p-interacting protein genetic 1 1 1 Synthetic Growth Defect
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
URA1 YKL216W Dihydroorotate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
ZRT3 YKL175W Vacuolar membrane zinc transporter genetic 1 1 1 Synthetic Growth Defect
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
YPT32 YGL210W Rab family GTPase involved in the exocytic pathway genetic 1 1 1 Dosage Rescue
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Positive Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Synthetic Lethality
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Synthetic Lethality
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 1 1 1 Synthetic Lethality
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Synthetic Lethality
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Lethality
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Positive Genetic
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Positive Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Negative Genetic
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
URC2 YDR520C Putative Zn(II)2Cys6 motif containing transcription factor genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RAD10 YML095C Single-stranded DNA endonuclease (with Rad1p) genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Negative Genetic
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
YJR146W YJR146W Protein of unknown function genetic 1 1 1 Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
YLR278C YLR278C Zinc-cluster protein genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Synthetic Growth Defect
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Synthetic Growth Defect
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Negative Genetic
LYP1 YNL268W Lysine permease genetic 1 1 1 Synthetic Growth Defect
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
ALG2 YGL065C Mannosyltransferase in the N-linked glycosylation pathway genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 1 1 1 Synthetic Lethality
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Synthetic Growth Defect
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Positive Genetic
CNE1 YAL058W Calnexin genetic 1 1 1 Synthetic Growth Defect
ODC1 YPL134C Mitochondrial inner membrane transporter genetic 1 1 1 Synthetic Growth Defect
PDR16 YNL231C Phosphatidylinositol transfer protein (PITP) genetic 1 1 1 Dosage Growth Defect
OCT1 YKL134C Mitochondrial intermediate peptidase genetic 1 1 1 Synthetic Growth Defect
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic