| MID2 |
YLR332W |
O-glycosylated plasma membrane protein |
genetic |
6 |
3 |
5 |
Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
5 |
3 |
5 |
Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Phenotypic Suppression, Negative Genetic, Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression |
| ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| FYV8 |
YGR196C |
Protein of unknown function |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Dosage Lethality, Synthetic Lethality |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FAR7 |
YFR008W |
Protein involved in recovery from pheromone-induced cell cycle arrest |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| OST6 |
YML019W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TOS2 |
YGR221C |
Protein involved in localization of Cdc24p to the site of bud growth |
physical |
3 |
2 |
1 |
Two-hybrid, Two-hybrid, Affinity Capture-Western |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Rescue |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Rescue |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BNI1 |
YNL271C |
Formin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MKK2 |
YPL140C |
MAPKK involved in the protein kinase C signaling pathway |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPS7 |
YDR349C |
Putative GPI-anchored aspartic protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TIM21 |
YGR033C |
Nonessential component of the TIM23 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YNL134C |
YNL134C |
NADH-dependent aldehyde reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YNL058C |
YNL058C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AVT6 |
YER119C |
Vacuolar aspartate and glutamate exporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ECM7 |
YLR443W |
Putative integral membrane protein with a role in calcium uptake |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EMC10 |
YDR056C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| SIP4 |
YJL089W |
C6 zinc cluster transcriptional activator |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PMT6 |
YGR199W |
Protein O-mannosyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX7 |
YDR142C |
Peroxisomal signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNI1 |
YNL271C |
Formin |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL8 |
YJL063C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PIM1 |
YBL022C |
ATP-dependent Lon protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APP1 |
YNL094W |
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol |
physical |
1 |
1 |
1 |
Two-hybrid |
| ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS1 |
YNL192W |
Chitin synthase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUS1 |
YDL193W |
Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG20 |
YDL113C |
Sorting nexin family member |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIC19 |
YFR011C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DDI1 |
YER143W |
Aspartic-type endopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GFD1 |
YMR255W |
Coiled-coiled protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
physical |
1 |
1 |
1 |
Two-hybrid |
| PCL9 |
YDL179W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNS1 |
YJR131W |
Alpha-1,2-mannosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX14 |
YGL153W |
Central component of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAL1 |
YDR348C |
Protein of unknown function thought to be involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RHO2 |
YNL090W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
physical |
1 |
1 |
1 |
Two-hybrid |
| RHO2 |
YNL090W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
physical |
1 |
1 |
1 |
Two-hybrid |
| RHO4 |
YKR055W |
Non-essential small GTPase |
physical |
1 |
1 |
1 |
Two-hybrid |
| RHO4 |
YKR055W |
Non-essential small GTPase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP5 |
YER144C |
Putative ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Two-hybrid |
| YDR239C |
YDR239C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOS2 |
YGR221C |
Protein involved in localization of Cdc24p to the site of bud growth |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| YCR016W |
YCR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSK22 |
YCR073C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWM2 |
YNR004W |
Protein with a role in snRNA and snoRNA cap trimethylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STD1 |
YOR047C |
Protein involved in control of glucose-regulated gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMD5 |
YDR255C |
Component of GID Complex that confers ubiquitin ligase (U3) activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RQT4 |
YKR023W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMH18 |
YPR098C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR524C-B |
YDR524C-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR016W |
YGR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS62 |
YGR141W |
Vacuolar protein sorting (VPS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMH11 |
YJR085C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR061C |
YNR061C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Two-hybrid |
| PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCH1 |
YDL054C |
Protein with similarity to mammalian monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| FMP46 |
YKR049C |
Putative redox protein containing a thioredoxin fold |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABP140 |
YOR239W |
AdoMet-dependent tRNA methyltransferase and actin binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAD1 |
YDL045C |
Flavin adenine dinucleotide (FAD) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSE2 |
YHR143W |
Daughter cell-specific secreted protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTL1 |
YGR023W |
Putative plasma membrane sensor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLD1 |
YPR109W |
Component of Dsc E3 ligase complex in Golgi and endosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO87 |
YCR037C |
Low-affinity inorganic phosphate (Pi) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GMC1 |
YDR506C |
Protein involved in meiotic progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERD2 |
YBL040C |
HDEL receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HPM1 |
YIL110W |
AdoMet-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAX4 |
YGR036C |
Dolichyl pyrophosphate (Dol-P-P) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
