| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
5 |
3 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-RNA |
| RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
3 |
3 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
| NOG1 |
YPL093W |
Putative GTPase |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
3 |
2 |
2 |
Negative Genetic, Positive Genetic, Negative Genetic |
| RKR1 |
YMR247C |
RING domain E3 ubiquitin ligase |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Co-purification |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
| FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
| STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| URB1 |
YKL014C |
Protein required for the normal accumulation of 25S and 5.8S rRNAs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RQC1 |
YDR333C |
Component of the ribosome quality control complex (RQC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NOC2 |
YOR206W |
Protein involved in ribosome biogenesis |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LOC1 |
YFR001W |
Nucleolar protein involved in the asymmetric localization of ASH1 mRNA |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RLI1 |
YDR091C |
Essential Fe-S protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LSG1 |
YGL099W |
Putative GTPase involved in 60S ribosomal subunit biogenesis |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NOG2 |
YNR053C |
Putative GTPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ARB1 |
YER036C |
ATPase of the ATP-binding cassette (ABC) family |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
2 |
2 |
1 |
Co-fractionation, Affinity Capture-Western |
| TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
northern blot evidence |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IFH1 |
YLR223C |
Coactivator, regulates transcription of ribosomal protein (RP) genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-seq evidence |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP4 |
YPL043W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NSA1 |
YGL111W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF5 |
YPR041W |
Translation initiation factor eIF5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP15 |
YPR143W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP17 |
YDR412W |
5' exoribonuclease required for 5' end processing of pre-60S rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SNL1 |
YIL016W |
Ribosome-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SCD6 |
YPR129W |
Repressor of translation initiation |
physical |
1 |
1 |
1 |
Co-fractionation |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ZUO1 |
YGR285C |
Ribosome-associated chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VBA4 |
YDR119W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSA4 |
YER103W |
Heat shock protein that is highly induced upon stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPP1B |
YDL130W |
Ribosomal protein P1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YGR054W |
YGR054W |
Eukaryotic initiation factor eIF2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TCB2 |
YNL087W |
ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPB1 |
YCL054W |
AdoMet-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SVL3 |
YPL032C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YME2 |
YMR302C |
Integral inner mitochondrial membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YVH1 |
YIR026C |
Dual specificity protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRB1 |
YMR131C |
Specific assembly chaperone for ribosomal protein Rpl3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL36B |
YPL249C-A |
Ribosomal 60S subunit protein L36B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL18A |
YOL120C |
Ribosomal 60S subunit protein L18A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VID24 |
YBR105C |
GID Complex regulatory subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UTP30 |
YKR060W |
Subunit of U3-containing 90S preribosome complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YND1 |
YER005W |
Apyrase with wide substrate specificity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPA1 |
YER049W |
Prolyl hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP9 |
YER098W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGK1 |
YGL101W |
5'-deoxynucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL114W |
YGL114W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL242C |
YGL242C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM21 |
YGR033C |
Nonessential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAX4 |
YJL083W |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR172W |
YPR172W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMH1 |
YLR309C |
Protein involved in vesicular transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FUN12 |
YAL035W |
Translation initiation factor eIF5B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MTR4 |
YJL050W |
RNA duplex-sensing translocase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NPL3 |
YDR432W |
RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KAP95 |
YLR347C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMD2 |
YHR216W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF6 |
YDR496C |
Pumilio-homology domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUD20 |
YLR074C |
C2H2-type zinc finger protein required for ribosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATP11 |
YNL315C |
Molecular chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NSA2 |
YER126C |
Protein constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IPI3 |
YNL182C |
Component of the Rix1 complex and pre-replicative complexes (pre-RCs) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
physical |
1 |
1 |
1 |
Co-fractionation |
| ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN2 |
YDR283C |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FPR4 |
YLR449W |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| NAB6 |
YML117W |
Putative RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOC4 |
YPR144C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAI1 |
YGL246C |
Nuclear decapping endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE3 |
YGR204W |
Cytoplasmic trifunctional enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| REA1 |
YLR106C |
Huge dynein-related AAA-type ATPase (midasin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RBG1 |
YAL036C |
Member of the DRG family of GTP-binding proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO5 |
YNL180C |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ARP10 |
YDR106W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEF3 |
YNL014W |
Translational elongation factor EF-3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAP2 |
YBL091C |
Methionine aminopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Co-purification |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HMG2 |
YLR450W |
HMG-CoA reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDH3 |
YDL078C |
Peroxisomal malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRP1 |
YHR146W |
Protein that binds to cruciform DNA structures |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOT5 |
YPR072W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OTU1 |
YFL044C |
Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ENT1 |
YDL161W |
Epsin-like protein involved in endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HMG1 |
YML075C |
HMG-CoA reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIT1 |
YNR001C |
Mitochondrial citrate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBS2 |
YDR197W |
Mitochondrial translational activator of the COB mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV15 |
YBR210W |
Protein involved in export of proteins from the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAP1 |
YLR244C |
Methionine aminopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAM1 |
YDR251W |
Essential protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF4 |
YGL014W |
Member of the PUF protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDP1 |
YDL066W |
Mitochondrial NADP-specific isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFG1 |
YGR271C-A |
Ribosome biogenesis factor required for maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OAC1 |
YKL120W |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBT1 |
YKL208W |
Protein involved in 5' RNA end processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HMI1 |
YOL095C |
Mitochondrial inner membrane localized ATP-dependent DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |