| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
23 |
5 |
18 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
physical |
8 |
4 |
5 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
physical |
6 |
4 |
6 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, FRET, Affinity Capture-MS |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
physical |
6 |
4 |
6 |
Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex |
| SAR1 |
YPL218W |
ARF family GTPase |
physical |
5 |
3 |
5 |
Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-purification, Affinity Capture-MS |
| GRH1 |
YDR517W |
Acetylated cis-Golgi protein, homolog of human GRASP65 |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
physical |
5 |
3 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
5 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
| SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
genetic |
4 |
3 |
4 |
Dosage Rescue, Dosage Rescue, Synthetic Lethality, Negative Genetic |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SEC22 |
YLR268W |
R-SNARE protein |
physical |
3 |
3 |
3 |
Affinity Capture-Western, FRET, Affinity Capture-MS |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
| IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| EMP24 |
YGL200C |
Component of the p24 complex |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-MS |
| SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| PDR17 |
YNL264C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Lethality |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHS2 |
YBR038W |
Chitin synthase II |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RSF2 |
YJR127C |
Zinc-finger protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEL3 |
YPL263C |
Cytoplasmic protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIR2 |
YDL175C |
RNA-binding subunit of the TRAMP nuclear RNA surveillance complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYS4 |
YGR155W |
Cystathionine beta-synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ECM29 |
YHL030W |
Scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP6 |
YBR055C |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC21 |
YNL287W |
Gamma subunit of coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
physical |
1 |
1 |
1 |
Two-hybrid |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ARF2 |
YDL137W |
ADP-ribosylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDD1 |
YLR245C |
Cytidine deaminase |
physical |
1 |
1 |
1 |
Two-hybrid |
| LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
physical |
1 |
1 |
1 |
Two-hybrid |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MST27 |
YGL051W |
Putative integral membrane protein, involved in vesicle formation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEP12 |
YOR036W |
Target membrane receptor (t-SNARE) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMP46 |
YLR080W |
Integral membrane component of ER-derived COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMP47 |
YFL048C |
Integral membrane component of ER-derived COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MST28 |
YAR033W |
Putative integral membrane protein, involved in vesicle formation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PRM8 |
YGL053W |
Pheromone-regulated protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SEC7 |
YDR170C |
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIF1 |
YNL263C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIP1 |
YGR172C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TVP38 |
YKR088C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOP1 |
YPR028W |
Reticulon-interacting protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT52 |
YKR014C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFT1 |
YKL006C-A |
Intra-Golgi v-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIP3 |
YNL044W |
Protein localized to COPII vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT31 |
YER031C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFT2 |
YBL102W |
Tetra-spanning membrane protein found mostly in the late Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSP120 |
YLR250W |
Protein packaged into COPII vesicles for ER to Golgi trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT1 |
YFL038C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSO1 |
YPL232W |
Plasma membrane t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
PCA |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SMY2 |
YBR172C |
GYF domain protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TTI2 |
YJR136C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YCR051W |
YCR051W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YCR102C |
YCR102C |
Putative quinone oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STF2 |
YGR008C |
Protein involved in resistance to desiccation stress |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UGX2 |
YDL169C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL242C |
YGL242C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VEL1 |
YGL258W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR142W |
YJR142W |
8-oxo-dGTP diphosphatase of the Nudix hydrolase family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR407W |
YLR407W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR071W |
YBR071W |
Protein of unknown function found in the cytoplasm and bud neck |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR154C-H |
YLR154C-H |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR295C |
YMR295C |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNK1 |
YKL171W |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NNK1 |
YKL171W |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
physical |
1 |
1 |
1 |
Two-hybrid |
| BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERV15 |
YBR210W |
Protein involved in export of proteins from the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWP2 |
YKL096W-A |
Covalently linked cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDA1 |
YLR307W |
Chitin deacetylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADD37 |
YMR184W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RNH70 |
YGR276C |
3'-5' exoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNF2 |
YDR093W |
Aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRY2 |
YKR013W |
Sterol binding protein involved in the export of acetylated sterols |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DUS4 |
YLR405W |
Dihydrouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AGC1 |
YPR021C |
Mitochondrial amino acid transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ENB1 |
YOL158C |
Ferric enterobactin transmembrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATX2 |
YOR079C |
Golgi membrane protein involved in manganese homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Positive Genetic |