| CMD1 |
YBR109C |
Calmodulin |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Biochemical Activity |
| PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
3 |
3 |
2 |
Phenotypic Suppression, Dosage Rescue, Synthetic Rescue |
| BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| GRX4 |
YER174C |
Glutathione-dependent oxidoreductase and glutathione S-transferase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| SDL1 |
YIL167W |
Blocked reading frame otherwise encoding L-serine dehydratase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| ERS1 |
YCR075C |
Protein involved in cystine transport |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| CDA1 |
YLR307W |
Chitin deacetylase |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DIT2 |
YDR402C |
N-formyltyrosine oxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC40 |
YDR364C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADA2 |
YDR448W |
Transcription coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIP2 |
YGL208W |
One of three alternate beta subunits of the Snf1 kinase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHA2 |
YNL316C |
Prephenate dehydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPL39 |
YJL189W |
Ribosomal 60S subunit protein L39 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MMF1 |
YIL051C |
Mitochondrial protein required for transamination of isoleucine |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IDS2 |
YJL146W |
Protein involved in modulation of Ime2p activity during meiosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YHR112C |
YHR112C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSF2 |
YDR312W |
Protein required for ribosomal large subunit maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TMT1 |
YER175C |
Trans-aconitate methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPS26B |
YER131W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KXD1 |
YGL079W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IGD1 |
YFR017C |
Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SER33 |
YIL074C |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DRE2 |
YKR071C |
Component of the cytosolic Fe-S protein assembly (CIA) machinery |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NTH1 |
YDR001C |
Neutral trehalase, degrades trehalose |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MSN5 |
YDR335W |
Karyopherin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| OXA1 |
YER154W |
Mitochondrial inner membrane insertase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| REX2 |
YLR059C |
3'-5' RNA exonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NTH2 |
YBR001C |
Putative neutral trehalase, required for thermotolerance |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DOT5 |
YIL010W |
Nuclear thiol peroxidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DIF1 |
YLR437C |
Protein that regulates nuclear import of Rnr2p and Rnr4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| POX1 |
YGL205W |
Fatty-acyl coenzyme A oxidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| QCR6 |
YFR033C |
Subunit 6 of the ubiquinol cytochrome-c reductase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GIP2 |
YER054C |
Putative regulatory subunit of protein phosphatase Glc7p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MGS1 |
YNL218W |
Protein with DNA-dependent ATPase and ssDNA annealing activities |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YLR030W |
YLR030W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRX1 |
YBL064C |
Mitochondrial peroxiredoxin with thioredoxin peroxidase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STR3 |
YGL184C |
Peroxisomal cystathionine beta-lyase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MAG1 |
YER142C |
3-methyl-adenine DNA glycosylase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FOX2 |
YKR009C |
3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSE2 |
YBR169C |
Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPO1 |
YLL028W |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NNR2 |
YKL151C |
Widely-conserved NADHX dehydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGL039W |
YGL039W |
Aldehyde reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PDS1 |
YDR113C |
Securin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VFA1 |
YER128W |
Protein that interacts with Vps4p and has a role in vacuolar sorting |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GCV1 |
YDR019C |
T subunit of the mitochondrial glycine decarboxylase complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
physical |
1 |
1 |
1 |
Biochemical Activity |
| JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EHT1 |
YBR177C |
Octanoyl-CoA:ethanol acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MNR2 |
YKL064W |
Vacuolar membrane protein required for magnesium homeostasis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR130C |
YGR130C |
Component of the eisosome with unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRM4 |
YPL156C |
Pheromone-regulated protein proposed to be involved in mating |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GTT3 |
YEL017W |
Protein of unknown function may be involved in glutathione metabolism |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DDI1 |
YER143W |
Aspartic-type endopeptidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RCF1 |
YML030W |
Cytochrome c oxidase subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RGD3 |
YHR182W |
GTPase activating protein (GAP) for Rho3p, involved in cell polarity g |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRP4 |
YDR354W |
Anthranilate phosphoribosyl transferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MFT1 |
YML062C |
Subunit of the THO complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NBP1 |
YLR457C |
Spindle pole body (SPB) component |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IRC19 |
YLL033W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GLG2 |
YJL137C |
Glycogenin glucosyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPO26 |
YPR187W |
RNA polymerase subunit ABC23 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NEJ1 |
YLR265C |
DNA end-binding protein required for nonhomologous end joining (NHEJ) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MRF1 |
YGL143C |
Mitochondrial translation release factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PIR5 |
YJL160C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NUP49 |
YGL172W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DDR48 |
YMR173W |
DNA damage-responsive protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DBR1 |
YKL149C |
RNA lariat debranching enzyme |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PDL32 |
YMR087W |
Putative ADP-ribose-1''-monophosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PMU1 |
YKL128C |
Putative phosphomutase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MDM36 |
YPR083W |
Mitochondrial protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RDS2 |
YPL133C |
Transcription factor involved in regulating gluconeogenesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FRT2 |
YAL028W |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MSP1 |
YGR028W |
Highly-conserved N-terminally anchored AAA-ATPase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ECM3 |
YOR092W |
Non-essential protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CYB5 |
YNL111C |
Cytochrome b5 |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| FSF1 |
YOR271C |
Putative protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RAS1 |
YOR101W |
GTPase involved in G-protein signaling in adenylate cyclase activation |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RTR1 |
YER139C |
Dual specificity protein phosphatase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SER1 |
YOR184W |
3-phosphoserine aminotransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YHR033W |
YHR033W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| EFM3 |
YJR129C |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YNR064C |
YNR064C |
Epoxide hydrolase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTC3 |
YHR087W |
Protein of unknown function involved in RNA metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YPD1 |
YDL235C |
Osmotic stress-responsive phosphorelay intermediate sensor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRK1 |
YDL079C |
Glycogen synthase kinase 3 (GSK-3) homolog |
genetic |
1 |
1 |
1 |
Positive Genetic |
| WWM1 |
YFL010C |
WW domain containing protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YVH1 |
YIR026C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HRI1 |
YLR301W |
Protein of unknown function that interacts with Sec72p and Hrr25p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YSP3 |
YOR003W |
Putative precursor of the subtilisin-like protease III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YGR027W-B |
YGR027W-B |
Retrotransposon TYA Gag and TYB Pol genes |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| MRX16 |
YDR132C |
Protein that associates with the large mitoribosomal subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNA4 |
YDL123W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| EAR1 |
YMR171C |
Specificity factor required for Rsp5p-dependent ubiquitination |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| TGL4 |
YKR089C |
Multifunctional lipase/hydrolase/phospholipase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| GEA2 |
YEL022W |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE8 |
YML092C |
Alpha 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MTR10 |
YOR160W |
Nuclear import receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YDR524C-B |
YDR524C-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GTA1 |
YEL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YER187W |
YER187W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAP1 |
YLR256W |
Zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNU23 |
YDL098C |
Component of the U4/U6.U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEN2 |
YLR105C |
Subunit of the tRNA splicing endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP8 |
YOL144W |
Nucleolar protein required for 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP21 |
YBL090W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL32 |
YCR003W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EGO2 |
YCR075W-A |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL124W |
YDL124W |
NADPH-dependent alpha-keto amide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UGX2 |
YDL169C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL036W |
YGL036W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR153W |
YGR153W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMT4 |
YJR143C |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR230W-A |
YMR230W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL033W |
YNL033W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP10 |
YDR106W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APT1 |
YML022W |
Adenine phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| APC9 |
YLR102C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC31 |
YOR257W |
Calcium-binding component of the spindle pole body (SPB) half-bridge |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG8 |
YBL078C |
Ub-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BIK1 |
YCL029C |
Microtubule-associated protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AZF1 |
YOR113W |
Zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CBP1 |
YJL209W |
Mitochondrial protein, regulator of COB mRNA stability and translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABZ1 |
YNR033W |
Para-aminobenzoate (PABA) synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AVT1 |
YJR001W |
Vacuolar transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AQY3 |
YFL054C |
Putative channel-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG21 |
YPL100W |
Phosphoinositide binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AIM29 |
YKR074W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ALO1 |
YML086C |
D-Arabinono-1,4-lactone oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AIF1 |
YNR074C |
Mitochondrial cell death effector |
genetic |
1 |
1 |
1 |
Positive Genetic |