Standard name Systematic name Name description Description
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) RNA export factor associated with the nuclear pore complex (NPC); associates with NUP116p; required for polyadenylated RNA export but not for protein import; homologous to S. pombe Rae1p and human RAE1
Visualize the interactome of GLE2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.065 NaN 0.205
Nuc Periphery 0.460 0.305 0.323
Nucleolus 0.081 NaN 0.061
Vac/Vac Memb 0.637 0.809 0.517
Endosome NaN 0.057 0.208

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nuclear periphery 1820

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GLE2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 16 5 10 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 6 4 5 Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex genetic 4 2 4 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 4 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 4 3 3 Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
SAC3 YDR159W mRNA export factor genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 3 2 3 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CRM1 YGR218W Nuclear export factor, exportin genetic 2 2 2 Synthetic Lethality, Negative Genetic
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex physical 2 2 2 Affinity Capture-MS, Two-hybrid
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 2 2 2 Synthetic Lethality, Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
LCB2 YDR062W Component of serine palmitoyltransferase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SMD1 YGR074W Core Sm protein Sm D1 genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SEC22 YLR268W R-SNARE protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
LCB1 YMR296C Component of serine palmitoyltransferase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CDC53 YDL132W Cullin genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 2 2 2 Synthetic Growth Defect, Dosage Rescue
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 2 1 2 Negative Genetic, Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 1 2 Negative Genetic, Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex genetic 2 1 2 Negative Genetic, Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 2 1 2 Negative Genetic, Negative Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 2 1 2 Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 2 1 2 Negative Genetic, Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 1 2 Negative Genetic, Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 2 1 2 Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 2 1 2 Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 2 1 2 Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 2 1 2 Negative Genetic, Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
STE24 YJR117W Highly conserved zinc metalloprotease genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation genetic 2 1 2 Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 2 1 2 Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 2 Negative Genetic, Negative Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 2 1 2 Negative Genetic, Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 2 1 2 Negative Genetic, Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 2 1 2 Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SLK19 YOR195W Kinetochore-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 2 1 2 Negative Genetic, Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 2 1 2 Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 1 2 Negative Genetic, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 2 1 2 Negative Genetic, Negative Genetic
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 2 1 2 Negative Genetic, Negative Genetic
ATG8 YBL078C Ub-like protein genetic 2 1 2 Negative Genetic, Negative Genetic
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 2 1 2 Negative Genetic, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 1 2 Negative Genetic, Negative Genetic
DCV1 YFR012W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 2 1 Synthetic Growth Defect, Dosage Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Synthetic Growth Defect
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Synthetic Growth Defect
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Synthetic Growth Defect
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-Western
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Synthetic Growth Defect
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 1 1 1 Affinity Capture-Western
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Growth Defect
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Positive Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Positive Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Synthetic Lethality
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Synthetic Growth Defect
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Positive Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Synthetic Growth Defect
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Synthetic Growth Defect
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Synthetic Growth Defect
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor physical 1 1 1 Affinity Capture-Western
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Synthetic Growth Defect
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) physical 1 1 1 Affinity Capture-Western
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 1 1 1 Synthetic Growth Defect
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs genetic 1 1 1 Synthetic Growth Defect
ERO1 YML130C Thiol oxidase required for oxidative protein folding in the ER genetic 1 1 1 Synthetic Growth Defect
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Synthetic Growth Defect
PRO1 YDR300C Gamma-glutamyl kinase physical 1 1 1 Affinity Capture-MS
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Dosage Rescue
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 1 1 1 Affinity Capture-MS
SAC3 YDR159W mRNA export factor physical 1 1 1 Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 1 1 1 Affinity Capture-MS
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Synthetic Growth Defect
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Two-hybrid
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit physical 1 1 1 Affinity Capture-Western
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit genetic 1 1 1 Synthetic Lethality
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) physical 1 1 1 Reconstituted Complex
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
SNL1 YIL016W Ribosome-associated protein genetic 1 1 1 Dosage Rescue
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Synthetic Lethality
RTN1 YDR233C Reticulon protein genetic 1 1 1 Synthetic Lethality
YOP1 YPR028W Reticulon-interacting protein genetic 1 1 1 Synthetic Lethality
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Lethality
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Synthetic Lethality
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Positive Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 1 1 1 Positive Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Positive Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Positive Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Positive Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Positive Genetic
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Positive Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
GSP1 YLR293C Ran GTPase genetic 1 1 1 Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 1 1 1 Negative Genetic
VPS62 YGR141W Vacuolar protein sorting (VPS) protein genetic 1 1 1 Negative Genetic
PBP1 YGR178C Component of glucose deprivation induced stress granules genetic 1 1 1 Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 1 1 1 Negative Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Synthetic Growth Defect
SFH1 YLR321C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Synthetic Growth Defect
MPS3 YJL019W Nuclear envelope protein genetic 1 1 1 Synthetic Growth Defect
NNF1 YJR112W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Synthetic Growth Defect
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Synthetic Growth Defect
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Synthetic Growth Defect
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Synthetic Growth Defect
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Synthetic Growth Defect
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Synthetic Growth Defect
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Synthetic Growth Defect
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Synthetic Growth Defect
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Synthetic Growth Defect
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 1 1 1 Synthetic Growth Defect
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Synthetic Growth Defect
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Synthetic Growth Defect
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Synthetic Growth Defect
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Synthetic Growth Defect
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Synthetic Growth Defect
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Synthetic Growth Defect
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Synthetic Growth Defect
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Synthetic Growth Defect
SPT15 YER148W TATA-binding protein (TBP) genetic 1 1 1 Synthetic Growth Defect
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Synthetic Growth Defect
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Synthetic Growth Defect
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Synthetic Growth Defect
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Synthetic Growth Defect
TFB3 YDR460W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Synthetic Growth Defect
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Synthetic Growth Defect
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Synthetic Growth Defect
MCM2 YBL023C Protein involved in DNA replication genetic 1 1 1 Synthetic Growth Defect
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Synthetic Growth Defect
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Synthetic Growth Defect
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Synthetic Growth Defect
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Synthetic Growth Defect
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Synthetic Growth Defect
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Synthetic Growth Defect
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Synthetic Growth Defect
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Synthetic Growth Defect
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Growth Defect
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Synthetic Growth Defect
SEC21 YNL287W Gamma subunit of coatomer genetic 1 1 1 Synthetic Growth Defect
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Synthetic Growth Defect
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Synthetic Growth Defect
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Synthetic Growth Defect
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic genetic 1 1 1 Synthetic Growth Defect
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Synthetic Growth Defect
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 1 1 1 Synthetic Growth Defect
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Synthetic Growth Defect
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Synthetic Growth Defect
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Synthetic Growth Defect
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Synthetic Growth Defect
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Synthetic Growth Defect
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 1 1 1 Synthetic Growth Defect
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 1 1 1 Synthetic Growth Defect
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Synthetic Growth Defect
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination genetic 1 1 1 Synthetic Growth Defect
URA6 YKL024C Uridylate kinase genetic 1 1 1 Synthetic Growth Defect
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs genetic 1 1 1 Synthetic Lethality
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Growth Defect
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export physical 1 1 1 Affinity Capture-MS
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Synthetic Growth Defect
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Affinity Capture-Western
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Synthetic Growth Defect
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Synthetic Growth Defect
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Synthetic Growth Defect
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Synthetic Growth Defect
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Synthetic Growth Defect
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Synthetic Growth Defect
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion genetic 1 1 1 Synthetic Growth Defect
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Negative Genetic
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 1 1 1 Synthetic Growth Defect
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Negative Genetic
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
CLB3 YDL155W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Positive Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Positive Genetic
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Positive Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Positive Genetic
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Synthetic Growth Defect
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic