| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
physical |
9 |
3 |
8 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS |
| RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
8 |
5 |
7 |
Reconstituted Complex, Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Two-hybrid |
| RAD24 |
YER173W |
Checkpoint protein |
physical |
8 |
5 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-purification, Co-fractionation, Co-purification |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
physical |
7 |
4 |
6 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-purification |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
7 |
2 |
5 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
6 |
2 |
5 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
physical |
5 |
3 |
5 |
Reconstituted Complex, Reconstituted Complex, FRET, Co-crystal Structure, Reconstituted Complex |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
5 |
2 |
5 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality |
| RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
5 |
4 |
4 |
Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
4 |
2 |
4 |
Dosage Rescue, Negative Genetic, Dosage Rescue, Negative Genetic |
| RFC3 |
YNL290W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Positive Genetic |
| MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
3 |
2 |
1 |
Positive Genetic, Negative Genetic, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| SLD5 |
YDR489W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HHT1 |
YBR010W |
Histone H3 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAD61 |
YDR014W |
Subunit of a complex that inhibits sister chromatid cohesion |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Phenotypic Enhancement |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PRI2 |
YKL045W |
Subunit of DNA primase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSF2 |
YJL072C |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD20 |
YLR074C |
C2H2-type zinc finger protein required for ribosome assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC45 |
YLR103C |
DNA replication initiation factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIA2 |
YHR122W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDF2 |
YDL070W |
Protein involved in transcription initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HRP1 |
YOL123W |
Subunit of cleavage factor I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MCM6 |
YGL201C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MRM1 |
YOR201C |
Ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV4 |
YHR059W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP42 |
YDR171W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGS1 |
YNL218W |
Protein with DNA-dependent ATPase and ssDNA annealing activities |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR181C |
YMR181C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOP2 |
YNL088W |
Topoisomerase II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNU13 |
YEL026W |
RNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEL1 |
YBL088C |
Protein kinase primarily involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBT1 |
YLL048C |
Transporter of the ATP-binding cassette (ABC) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SPC98 |
YNL126W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL032C |
YLL032C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAR029W |
YAR029W |
Member of DUP240 gene family but contains no transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UGO1 |
YDR470C |
Outer membrane component of the mitochondrial fusion machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZUO1 |
YGR285C |
Ribosome-associated chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML100W-A |
YML100W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR072W-B |
YOR072W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH203 |
YLR154C |
Ribonuclease H2 subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| DDC1 |
YPL194W |
DNA damage checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDS1 |
YDR113C |
Securin |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS116 |
YDR194C |
Mitochondrial transcription elongation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUT1 |
YBR252W |
Deoxyuridine triphosphate diphosphatase (dUTPase) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PEX15 |
YOL044W |
Tail-anchored type II integral peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDR17 |
YNL264C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
physical |
1 |
1 |
1 |
Two-hybrid |
| IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARK1 |
YNL020C |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSB4 |
YOL112W |
GTPase-activating protein of the Ras superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHT2 |
YNL031C |
Histone H3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EIS1 |
YMR031C |
Component of the eisosome required for proper eisosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IFH1 |
YLR223C |
Coactivator, regulates transcription of ribosomal protein (RP) genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MSF1 |
YPR047W |
Mitochondrial phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| AIM11 |
YER093C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC5 |
YFR038W |
Putative ATPase containing the DEAD/H helicase-related sequence motif |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PNP1 |
YLR209C |
Purine nucleoside phosphorylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COA1 |
YIL157C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSA1 |
YOR066W |
Activator of G1-specific transcription factors MBF and SBF |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OAC1 |
YKL120W |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPT1 |
YDR399W |
Dimeric hypoxanthine-guanine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| APA2 |
YDR530C |
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MYG1 |
YER156C |
Protein involved in mitochondrial function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AGC1 |
YPR021C |
Mitochondrial amino acid transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
