| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
5 |
3 |
3 |
Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Suppression, Positive Genetic, Positive Genetic |
| HOL1 |
YNR055C |
Putative transporter in the major facilitator superfamily |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| SDP1 |
YIL113W |
Stress-inducible dual-specificity MAP kinase phosphatase |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| RLI1 |
YDR091C |
Essential Fe-S protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| FAR3 |
YMR052W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPK9 |
YOR291W |
Vacuolar protein with a possible role in sequestering heavy metals |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAU17 |
YLL025W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Dosage Growth Defect |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AIM25 |
YJR100C |
Mitochondria protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS21 |
YEL019C |
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX7 |
YDR142C |
Peroxisomal signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATP11 |
YNL315C |
Molecular chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BDF2 |
YDL070W |
Protein involved in transcription initiation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IMG1 |
YCR046C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL39 |
YML009C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AHA1 |
YDR214W |
Co-chaperone that binds Hsp82p and activates its ATPase activity |
physical |
1 |
1 |
1 |
Two-hybrid |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPH22 |
YDL188C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BLM10 |
YFL007W |
Proteasome activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC21 |
YNL287W |
Gamma subunit of coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAK1 |
YER129W |
Upstream serine/threonine kinase for the SNF1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL3 |
YIR032C |
Ureidoglycolate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FET3 |
YMR058W |
Ferro-O2-oxidoreductase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXT7 |
YDR342C |
High-affinity glucose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP53 |
YPL146C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIC19 |
YFR011C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM11 |
YMR139W |
Protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BNA5 |
YLR231C |
Kynureninase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNR3 |
YIL066C |
Minor isoform of large subunit of ribonucleotide-diphosphate reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PET191 |
YJR034W |
Protein required for assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNS1 |
YJR131W |
Alpha-1,2-mannosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESL1 |
YIL151C |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRS1 |
YIR021W |
Splicing protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SGM1 |
YJR134C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNL1 |
YIL016W |
Ribosome-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNR1 |
YIL159W |
Formin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FBP1 |
YLR377C |
Fructose-1,6-bisphosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATC1 |
YDR184C |
Nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRI1 |
YPR118W |
5'-methylthioribose-1-phosphate isomerase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MSB3 |
YNL293W |
Rab GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DYS1 |
YHR068W |
Deoxyhypusine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOT13 |
YKL084W |
Zinc-binding mitochondrial intermembrane space (IMS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEU1 |
YLR017W |
Methylthioadenosine phosphorylase (MTAP) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ARO80 |
YDR421W |
Zinc finger transcriptional activator of the Zn2Cys6 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANT1 |
YPR128C |
Peroxisomal adenine nucleotide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PYK2 |
YOR347C |
Pyruvate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXP1 |
YDL121C |
A cargo receptor protein for Pma1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSI1 |
YDR026C |
RNA polymerase I termination factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEL1 |
YHR035W |
Activator of Sar1p GTPase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUL3 |
YGR003W |
Ubiquitin-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPT1 |
YGR123C |
Protein serine/threonine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IZH3 |
YLR023C |
Membrane protein involved in zinc ion homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INA17 |
YPL099C |
F1F0 ATPase synthase peripheral stalk assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IDP1 |
YDL066W |
Mitochondrial NADP-specific isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC7 |
YLR385C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRY1 |
YKL218C |
3-hydroxyaspartate dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC10 |
YBR265W |
3-ketosphinganine reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRX3 |
YCR083W |
Mitochondrial thioredoxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI22 |
YPR121W |
Protein with similarity to hydroxymethylpyrimidine phosphate kinases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URH1 |
YDR400W |
Uridine nucleosidase (uridine-cytidine N-ribohydrolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| URA8 |
YJR103W |
Minor CTP synthase isozyme (see also URA7) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTR5 |
YEL035C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THG1 |
YGR024C |
tRNAHis guanylyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAE1 |
YJR067C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL124W |
YDL124W |
NADPH-dependent alpha-keto amide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YEF1 |
YEL041W |
ATP-NADH kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMT1 |
YER175C |
Trans-aconitate methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO11 |
YHL022C |
Meiosis-specific protein required for meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRX1 |
YKL086W |
Sulfiredoxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL006W-A |
YLL006W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR030W-A |
YMR030W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA64 |
YDR117C |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL070C |
YJL070C |
Putative metallo-dependent hydrolase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR296W |
YOR296W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM44 |
YPL030W |
tRNA(Ser) Um(44) 2'-O-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR159C-A |
YPR159C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YNK1 |
YKL067W |
Nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR179C |
YLR179C |
Protein of unknown function with similarity to Tfs1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TFS1 |
YLR178C |
Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TOS3 |
YGL179C |
Protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKL091C |
YKL091C |
Putative phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEL1 |
YBL088C |
Protein kinase primarily involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YUH1 |
YJR099W |
Ubiquitin C-terminal hydrolase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UTP30 |
YKR060W |
Subunit of U3-containing 90S preribosome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISR1 |
YPR106W |
Predicted protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISF1 |
YMR081C |
Serine-rich, hydrophilic protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAP2 |
YHR028C |
Dipeptidyl aminopeptidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QNS1 |
YHR074W |
Glutamine-dependent NAD(+) synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSR2 |
YLR019W |
Putative plasma membrane phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EAR1 |
YMR171C |
Specificity factor required for Rsp5p-dependent ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NIT3 |
YLR351C |
Nit protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DFG10 |
YIL049W |
Probable polyprenol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AFT2 |
YPL202C |
Iron-regulated transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| COX9 |
YDL067C |
Subunit VIIa of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBI1 |
YPL272C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC10 |
YDR056C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAU1 |
YER183C |
5,10-methenyltetrahydrofolate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRK1 |
YDL079C |
Glycogen synthase kinase 3 (GSK-3) homolog |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMP2 |
YMR035W |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXT9 |
YJL219W |
Putative hexose transporter that is nearly identical to Hxt11p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIC2 |
YER053C |
Mitochondrial copper and phosphate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADY2 |
YCR010C |
Acetate transporter required for normal sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FEN2 |
YCR028C |
Plasma membrane H+-pantothenate symporter |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QRI5 |
YLR204W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT2 |
YHR037W |
Delta-1-pyrroline-5-carboxylate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT1 |
YLR142W |
Proline oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IDP2 |
YLR174W |
Cytosolic NADP-specific isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NIT2 |
YJL126W |
Nit protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PCP1 |
YGR101W |
Mitochondrial serine protease |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RAD61 |
YDR014W |
Subunit of a complex that inhibits sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLO1 |
YER180C-A |
Protein interacting with Arl3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNE1 |
YOR350C |
Protein involved in splicing Group I aI5-beta intron from COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHH4 |
YLR164W |
Putative alternate subunit of succinate dehydrogenase (SDH) |
genetic |
1 |
1 |
1 |
Negative Genetic |
