Standard name Systematic name Name description Description
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) Alpha subunit of the nascent polypeptide-associated complex (NAC); involved in protein sorting and translocation; associated with cytoplasmic ribosomes
Visualize the interactome of EGD2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.994 0.992 0.995

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 38000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
EGD2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) physical 12 6 10 Affinity Capture-Western, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-purification, PCA, Affinity Capture-MS
OM14 YBR230C Mitochondrial outer membrane receptor for cytosolic ribosomes physical 3 2 2 PCA, Affinity Capture-Western, PCA
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 3 3 1 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 2 2 2 Affinity Capture-MS, Two-hybrid
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
UBP14 YBR058C Ubiquitin-specific protease genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SRY1 YKL218C 3-hydroxyaspartate dehydratase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 2 2 2 Negative Genetic, Synthetic Lethality
SUP35 YDR172W Translation termination factor eRF3 genetic 2 2 2 Phenotypic Suppression, Positive Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 2 2 Negative Genetic, Positive Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
ATG8 YBL078C Ub-like protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 2 1 2 Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ATG1 YGL180W Protein serine/threonine kinase genetic 2 1 2 Negative Genetic, Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 2 2 1 Co-fractionation, Affinity Capture-Western
GAP1 YKR039W General amino acid permease physical 2 2 1 Two-hybrid, Affinity Capture-Western
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway physical 2 2 1 Two-hybrid, Affinity Capture-Western
KAR2 YJL034W ATPase involved in protein import into the ER genetic 2 2 1 Negative Genetic, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
MET31 YPL038W Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSP5 YER125W NEDD4 family E3 ubiquitin ligase regulation 1 1 1 qualitative western immunoblotting evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Synthetic Growth Defect
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly genetic 1 1 1 Synthetic Growth Defect
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 PCA
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Synthetic Growth Defect
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
CPA2 YJR109C Large subunit of carbamoyl phosphate synthetase genetic 1 1 1 Synthetic Growth Defect
ADE3 YGR204W Cytoplasmic trifunctional enzyme genetic 1 1 1 Synthetic Growth Defect
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 Affinity Capture-MS
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
GTB1 YDR221W Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p physical 1 1 1 Affinity Capture-MS
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
YJR011C YJR011C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
SIP5 YMR140W Protein of unknown function physical 1 1 1 Affinity Capture-MS
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation physical 1 1 1 Affinity Capture-MS
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Two-hybrid
UBC5 YDR059C Ubiquitin-conjugating enzyme physical 1 1 1 Two-hybrid
SPE4 YLR146C Spermine synthase physical 1 1 1 Two-hybrid
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-Western
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPL17A YKL180W Ribosomal 60S subunit protein L17A physical 1 1 1 Co-purification
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex physical 1 1 1 Affinity Capture-Western
SRP72 YPL210C Core component of the signal recognition particle (SRP) physical 1 1 1 Affinity Capture-Western
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Biochemical Activity
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
TRM112 YNR046W Protein involved in methylation of tRNA, rRNA, and translation factors physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 PCA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p physical 1 1 1 PCA
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter physical 1 1 1 PCA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Reconstituted Complex
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 1 1 1 PCA
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes genetic 1 1 1 Synthetic Growth Defect
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 PCA
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Synthetic Growth Defect
RPL35A YDL191W Ribosomal 60S subunit protein L35A physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Two-hybrid
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 Two-hybrid
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Phenotypic Enhancement
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
SIP4 YJL089W C6 zinc cluster transcriptional activator genetic 1 1 1 Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SVL3 YPL032C Protein of unknown function genetic 1 1 1 Negative Genetic
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Synthetic Growth Defect
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Synthetic Growth Defect
YPK9 YOR291W Vacuolar protein with a possible role in sequestering heavy metals genetic 1 1 1 Phenotypic Suppression
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Positive Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport genetic 1 1 1 Phenotypic Enhancement
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
UBX3 YDL091C Clathrin-coated vesicle component, regulator of endocytosis genetic 1 1 1 Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Negative Genetic
FTR1 YER145C High affinity iron permease genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
YGL036W YGL036W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR017W YGR017W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RAX2 YLR084C Protein required for the maintenance of bud site selection genetic 1 1 1 Negative Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 1 1 1 Negative Genetic
RSF1 YMR030W Protein required for respiratory growth genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
MPC54 YOR177C Component of the meiotic outer plaque genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Synthetic Growth Defect
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
LYS4 YDR234W Homoaconitase genetic 1 1 1 Synthetic Growth Defect
MSW1 YDR268W Mitochondrial tryptophanyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
PUF4 YGL014W Member of the PUF protein family genetic 1 1 1 Synthetic Growth Defect
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Synthetic Growth Defect
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Synthetic Growth Defect
LYS5 YGL154C Phosphopantetheinyl transferase involved in lysine biosynthesis genetic 1 1 1 Synthetic Growth Defect
ORT1 YOR130C Ornithine transporter of the mitochondrial inner membrane genetic 1 1 1 Synthetic Growth Defect
LYS1 YIR034C Saccharopine dehydrogenase (NAD+, L-lysine-forming) genetic 1 1 1 Synthetic Growth Defect
YET1 YKL065C Endoplasmic reticulum transmembrane protein genetic 1 1 1 Synthetic Growth Defect
LYS2 YBR115C Alpha aminoadipate reductase genetic 1 1 1 Synthetic Growth Defect
KRE6 YPR159W Glucosyl hydrolase required for beta-1,6-glucan biosynthesis genetic 1 1 1 Synthetic Growth Defect
HIS7 YBR248C Imidazole glycerol phosphate synthase genetic 1 1 1 Synthetic Growth Defect
FUR4 YBR021W Plasma membrane localized uracil permease genetic 1 1 1 Synthetic Growth Defect
LYS12 YIL094C Homo-isocitrate dehydrogenase genetic 1 1 1 Synthetic Growth Defect
YOR302W YOR302W CPA1 uORF genetic 1 1 1 Synthetic Growth Defect
LYS9 YNR050C Saccharopine dehydrogenase (NADP+, L-glutamate-forming) genetic 1 1 1 Synthetic Growth Defect
HEF3 YNL014W Translational elongation factor EF-3 genetic 1 1 1 Synthetic Growth Defect
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
HIS5 YIL116W Histidinol-phosphate aminotransferase genetic 1 1 1 Synthetic Growth Defect
HIS1 YER055C ATP phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
RRG1 YDR065W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Synthetic Growth Defect
VPS16 YPL045W Subunit of the HOPS and the CORVET complexes genetic 1 1 1 Synthetic Growth Defect
RPB9 YGL070C RNA polymerase II subunit B12.6 genetic 1 1 1 Synthetic Growth Defect
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Synthetic Growth Defect
MSY1 YPL097W Mitochondrial tyrosyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
FEN2 YCR028C Plasma membrane H+-pantothenate symporter genetic 1 1 1 Synthetic Growth Defect
POS5 YPL188W Mitochondrial NADH kinase genetic 1 1 1 Synthetic Growth Defect
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase genetic 1 1 1 Synthetic Growth Defect
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA genetic 1 1 1 Synthetic Growth Defect
RPL13B YMR142C Ribosomal 60S subunit protein L13B genetic 1 1 1 Synthetic Growth Defect
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Synthetic Growth Defect
HIS2 YFR025C Histidinolphosphatase genetic 1 1 1 Synthetic Growth Defect
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
LYS14 YDR034C Transcriptional activator involved in regulating lysine biosynthesis genetic 1 1 1 Synthetic Growth Defect
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator genetic 1 1 1 Synthetic Growth Defect
MRX14 YDR115W Putative mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) genetic 1 1 1 Synthetic Growth Defect
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Synthetic Growth Defect
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
EMP24 YGL200C Component of the p24 complex genetic 1 1 1 Synthetic Growth Defect
MTL1 YGR023W Putative plasma membrane sensor genetic 1 1 1 Synthetic Growth Defect
SSD1 YDR293C Translational repressor genetic 1 1 1 Synthetic Growth Defect
PEX2 YJL210W RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
GNP1 YDR508C Broad specificity amino acid permease genetic 1 1 1 Synthetic Growth Defect
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Growth Defect
REF2 YDR195W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Synthetic Growth Defect
RPB4 YJL140W RNA polymerase II subunit B32 genetic 1 1 1 Synthetic Growth Defect
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Synthetic Growth Defect
GRX8 YLR364W Glutaredoxin that employs a dithiol mechanism of catalysis genetic 1 1 1 Synthetic Growth Defect
MTO1 YGL236C Mitochondrial protein genetic 1 1 1 Synthetic Growth Defect
VEL1 YGL258W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
INO2 YDR123C Transcription factor genetic 1 1 1 Synthetic Growth Defect
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains genetic 1 1 1 Synthetic Growth Defect
STE11 YLR362W Signal transducing MEK kinase genetic 1 1 1 Synthetic Growth Defect
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Synthetic Growth Defect
LCB5 YLR260W Minor sphingoid long-chain base kinase genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
RAI1 YGL246C Nuclear decapping endonuclease genetic 1 1 1 Synthetic Growth Defect
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Synthetic Growth Defect
YMR085W YMR085W Putative protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SRT1 YMR101C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Synthetic Growth Defect
TOM71 YHR117W Mitochondrial outer membrane protein genetic 1 1 1 Synthetic Growth Defect
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 1 1 1 Synthetic Growth Defect
LDB16 YCL005W Protein involved in lipid droplet (LD) assembly genetic 1 1 1 Synthetic Growth Defect
TUB3 YML124C Alpha-tubulin genetic 1 1 1 Synthetic Growth Defect
TVS1 YCR061W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Synthetic Growth Defect
GEP4 YHR100C Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) genetic 1 1 1 Synthetic Growth Defect
THR1 YHR025W Homoserine kinase genetic 1 1 1 Synthetic Growth Defect
HSL7 YBR133C Protein arginine N-methyltransferase genetic 1 1 1 Synthetic Growth Defect
GMC1 YDR506C Protein involved in meiotic progression genetic 1 1 1 Synthetic Growth Defect
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Positive Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Positive Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Positive Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Positive Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Positive Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Positive Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Phenotypic Suppression
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Phenotypic Suppression
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Phenotypic Suppression
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Synthetic Growth Defect
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Negative Genetic
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Phenotypic Enhancement
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Positive Genetic
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division physical 1 1 1 Affinity Capture-MS
ARG4 YHR018C Argininosuccinate lyase genetic 1 1 1 Synthetic Growth Defect
CPA1 YOR303W Small subunit of carbamoyl phosphate synthetase genetic 1 1 1 Synthetic Growth Defect
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
ARG1 YOL058W Arginosuccinate synthetase genetic 1 1 1 Synthetic Growth Defect
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Synthetic Growth Defect
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 PCA
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Synthetic Lethality
ARG3 YJL088W Ornithine carbamoyltransferase genetic 1 1 1 Synthetic Growth Defect
ACO2 YJL200C Putative mitochondrial aconitase isozyme genetic 1 1 1 Synthetic Growth Defect
ACF4 YJR083C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Positive Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Synthetic Growth Defect
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Growth Defect
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Synthetic Growth Defect
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Synthetic Growth Defect
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
DAL5 YJR152W Allantoate permease genetic 1 1 1 Synthetic Growth Defect
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Synthetic Growth Defect
ARG56 YER069W Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase genetic 1 1 1 Synthetic Growth Defect
DCG1 YIR030C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
CRS1 YNL247W Cysteinyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Synthetic Growth Defect
BAP2 YBR068C High-affinity leucine permease genetic 1 1 1 Synthetic Growth Defect
DPL1 YDR294C Dihydrosphingosine phosphate lyase genetic 1 1 1 Negative Genetic
AIM32 YML050W 2Fe-2S mitochondrial protein involved in redox quality control genetic 1 1 1 Synthetic Growth Defect
EFM4 YIL064W Lysine methyltransferase genetic 1 1 1 Synthetic Growth Defect
DCV1 YFR012W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
ARG2 YJL071W Acetylglutamate synthase (glutamate N-acetyltransferase) genetic 1 1 1 Synthetic Growth Defect
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Synthetic Growth Defect
ARG7 YMR062C Mitochondrial ornithine acetyltransferase genetic 1 1 1 Synthetic Growth Defect
CDA2 YLR308W Chitin deacetylase genetic 1 1 1 Synthetic Growth Defect