| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
physical |
44 |
8 |
31 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-localization, Affinity Capture-Western, Protein-peptide, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
30 |
6 |
21 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-localization, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Co-fractionation, Co-localization, Reconstituted Complex, Co-localization, Co-localization, Reconstituted Complex |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
23 |
3 |
17 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
17 |
3 |
11 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-localization |
| TOA1 |
YOR194C |
TFIIA large subunit |
physical |
16 |
2 |
16 |
Co-crystal Structure, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
| TAF11 |
YML015C |
TFIID subunit (40 kDa) |
physical |
15 |
4 |
12 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-localization, Affinity Capture-Western, Affinity Capture-MS |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
physical |
14 |
4 |
11 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-localization, Affinity Capture-Western, Affinity Capture-MS |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
physical |
14 |
3 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-localization |
| BRF1 |
YGR246C |
TFIIIB B-related factor |
physical |
13 |
5 |
13 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS |
| TOA2 |
YKL058W |
TFIIA small subunit |
physical |
13 |
2 |
13 |
Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
| TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
physical |
13 |
4 |
9 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-localization, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| TAF2 |
YCR042C |
TFIID subunit (150 kDa) |
physical |
13 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
physical |
12 |
5 |
10 |
Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-purification, Reconstituted Complex, Two-hybrid, Far Western, Reconstituted Complex |
| GAL4 |
YPL248C |
DNA-binding transcription factor required for activating GAL genes |
physical |
12 |
4 |
8 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, PCA |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
physical |
11 |
6 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-localization, Reconstituted Complex, Co-fractionation, Co-purification, Co-purification |
| TAF13 |
YML098W |
TFIID subunit (19 kDa) |
physical |
10 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-localization, Affinity Capture-Western, Affinity Capture-MS |
| TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
10 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| KAP114 |
YGL241W |
Karyopherin, responsible for nuclear import of specific proteins |
physical |
9 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
| TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
physical |
9 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-localization, Affinity Capture-MS |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
8 |
3 |
6 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Rescue, Dosage Rescue, Synthetic Rescue |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
physical |
8 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-localization, Affinity Capture-MS |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
7 |
3 |
5 |
Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-purification |
| TAF8 |
YML114C |
TFIID subunit (65 kDa) |
physical |
7 |
3 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-localization |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
6 |
4 |
4 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Enhancement |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
physical |
6 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-localization, Reconstituted Complex, Co-localization |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
physical |
6 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Co-localization, Reconstituted Complex, Reconstituted Complex, Co-localization |
| TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
physical |
6 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
physical |
6 |
2 |
2 |
Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
5 |
5 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Co-localization, Co-purification, Reconstituted Complex |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
physical |
5 |
5 |
4 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Co-fractionation, Reconstituted Complex |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
4 |
4 |
4 |
Affinity Capture-MS, Co-localization, Affinity Capture-Western, Co-purification |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
4 |
3 |
4 |
Reconstituted Complex, Co-localization, Affinity Capture-Western, Co-localization |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
4 |
3 |
4 |
Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
4 |
3 |
4 |
Dosage Rescue, Synthetic Lethality, Dosage Rescue, Synthetic Rescue |
| NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
| BRF1 |
YGR246C |
TFIIIB B-related factor |
genetic |
4 |
2 |
4 |
Dosage Rescue, Dosage Rescue, Synthetic Rescue, Dosage Rescue |
| TOA2 |
YKL058W |
TFIIA small subunit |
genetic |
4 |
1 |
3 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue |
| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
physical |
4 |
3 |
1 |
Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Synthetic Rescue, Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
| BDP1 |
YNL039W |
Essential subunit of RNA polymerase III transcription factor (TFIIIB) |
physical |
3 |
2 |
3 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
| TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
3 |
1 |
3 |
Dosage Rescue, Dosage Rescue, Dosage Rescue |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Dosage Rescue, Synthetic Rescue |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
3 |
3 |
2 |
Synthetic Growth Defect, Synthetic Lethality, Dosage Rescue |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| RRN6 |
YBL014C |
Component of the core factor (CF) rDNA transcription factor complex |
physical |
3 |
2 |
2 |
Reconstituted Complex, Two-hybrid, Reconstituted Complex |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
physical |
3 |
2 |
2 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
| NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
3 |
1 |
2 |
Dosage Rescue, Dosage Rescue, Dosage Rescue |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
3 |
3 |
1 |
Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
physical |
2 |
2 |
2 |
Co-fractionation, PCA |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| ADA2 |
YDR448W |
Transcription coactivator |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
| SRB4 |
YER022W |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
2 |
2 |
Co-purification, Reconstituted Complex |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-Western |
| TFC8 |
YPL007C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
| BDP1 |
YNL039W |
Essential subunit of RNA polymerase III transcription factor (TFIIIB) |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| STD1 |
YOR047C |
Protein involved in control of glucose-regulated gene expression |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
physical |
2 |
1 |
2 |
Reconstituted Complex, Reconstituted Complex |
| PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
physical |
2 |
1 |
2 |
Reconstituted Complex, Reconstituted Complex |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
| RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
| RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Phenotypic Suppression |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Dosage Rescue |
| STD1 |
YOR047C |
Protein involved in control of glucose-regulated gene expression |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Dosage Rescue |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
2 |
1 |
1 |
Co-localization, Co-localization |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NOT5 |
YPR072W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
2 |
1 |
1 |
Dosage Rescue, Dosage Rescue |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC3 |
YDR303C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Co-fractionation |
| RPN9 |
YDR427W |
Non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| BNI1 |
YNL271C |
Formin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK5 |
YBR142W |
Essential nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
PCA |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRM1 |
YOR201C |
Ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| KAP114 |
YGL241W |
Karyopherin, responsible for nuclear import of specific proteins |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP8 |
YHR169W |
ATPase, putative RNA helicase of the DEAD-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SRP21 |
YKL122C |
Subunit of the signal recognition particle (SRP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWI6 |
YLR182W |
Transcription cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TUB2 |
YFL037W |
Beta-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TFB2 |
YPL122C |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TFB4 |
YPR056W |
Subunit of TFIIH complex |
physical |
1 |
1 |
1 |
Co-purification |
| YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUB1 |
YMR039C |
Transcriptional regulator |
physical |
1 |
1 |
1 |
Co-localization |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TTI2 |
YJR136C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCL001W-A |
YCL001W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YNR075C-A |
YNR075C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC4 |
YGR047C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL134C-A |
YIL134C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR361C-A |
YLR361C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL019C |
YNL019C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGP1 |
YNL160W |
Cell wall-related secretory glycoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST3 |
YIR005W |
Component of the U2 snRNP |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMN1 |
YDR236C |
Riboflavin kinase, produces riboflavin monophosphate (FMN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT4 |
YOR348C |
Proline permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN10 |
YBL025W |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HOT1 |
YMR172W |
Transcription factor for glycerol biosynthetic genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFH1 |
YLR321C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO2 |
YDL106C |
Homeobox transcription factor |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| IMP1 |
YMR150C |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN11 |
YML043C |
Component of the core factor (CF) rDNA transcription factor complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC107 |
YJR021C |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PET494 |
YNR045W |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN5 |
YLR141W |
Protein involved in transcription of rDNA by RNA polymerase I |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUN26 |
YAL022C |
High affinity, broad selectivity, nucleoside/nucleobase transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COI1 |
YDR381C-A |
Mitochondrial assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EKI1 |
YDR147W |
Ethanolamine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRI2 |
YKL045W |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOS2 |
YDR068W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ8 |
YGL119W |
ATPase required for ubiquinone biosynthesis and respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIB5 |
YBR256C |
Riboflavin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAG1 |
YJR004C |
Alpha-agglutinin of alpha-cells |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRS5 |
YOR031W |
Copper-binding metallothionein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLD1 |
YPR109W |
Component of Dsc E3 ligase complex in Golgi and endosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX19 |
YDL183C |
Protein that may form an active mitochondrial KHE system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POF1 |
YCL047C |
Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEG2 |
YKL105C |
Eisosome component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
1 |
1 |
1 |
Negative Genetic |
