| MNL1 |
YHR204W |
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum |
physical |
9 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
| MPD2 |
YOL088C |
Member of the protein disulfide isomerase (PDI) family |
genetic |
5 |
4 |
4 |
Dosage Rescue, Synthetic Rescue, Dosage Rescue, Dosage Lethality, Negative Genetic |
| SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex |
| IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
4 |
2 |
2 |
Positive Genetic, Positive Genetic, Synthetic Lethality, Synthetic Lethality |
| HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
4 |
2 |
2 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
physical |
4 |
4 |
1 |
Co-crystal Structure, Affinity Capture-Western, Reconstituted Complex, PCA |
| EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
genetic |
3 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Synthetic Rescue |
| MPD1 |
YOR288C |
Member of the protein disulfide isomerase (PDI) family |
genetic |
3 |
2 |
3 |
Dosage Rescue, Dosage Rescue, Synthetic Rescue |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Synthetic Lethality |
| YUR1 |
YJL139C |
Mannosyltransferase involved in protein N-glycosylation |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| ROT2 |
YBR229C |
Glucosidase II catalytic subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
2 |
2 |
2 |
Protein-peptide, Affinity Capture-MS |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| PDL32 |
YMR087W |
Putative ADP-ribose-1''-monophosphatase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| EPS1 |
YIL005W |
ER protein with chaperone and co-chaperone activity |
genetic |
2 |
2 |
2 |
Dosage Rescue, Synthetic Rescue |
| ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
physical |
2 |
2 |
1 |
Affinity Capture-Western, PCA |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SEI1 |
YLR404W |
Seipin involved in lipid droplet (LD) assembly |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SNF8 |
YPL002C |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS25 |
YJR102C |
Component of the ESCRT-II complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SBH1 |
YER087C-B |
Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| KHA1 |
YJL094C |
Putative K+/H+ antiporter |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BNI1 |
YNL271C |
Formin |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL16 |
YBL038W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRK1 |
YOR267C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNL1 |
YHR204W |
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIG2 |
YDR480W |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PSK1 |
YAL017W |
PAS domain-containing serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSK22 |
YCR073C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TOS3 |
YGL179C |
Protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHO5 |
YBR093C |
Repressible acid phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
physical |
1 |
1 |
1 |
Protein-peptide |
| PRC1 |
YMR297W |
Vacuolar carboxypeptidase Y (proteinase C, CPY) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| POM33 |
YLL023C |
Transmembrane nucleoporin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VID24 |
YBR105C |
GID Complex regulatory subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RAD2 |
YGR258C |
Single-stranded DNA endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| WSS1 |
YHR134W |
SUMO-ligase and SUMO-targeted metalloprotease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| YGR237C |
YGR237C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| YAP1801 |
YHR161C |
Protein of the AP180 family, involved in clathrin cage assembly |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RSM10 |
YDR041W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RRN5 |
YLR141W |
Protein involved in transcription of rDNA by RNA polymerase I |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TRM9 |
YML014W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| YEL025C |
YEL025C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| YET3 |
YDL072C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SYC1 |
YOR179C |
Subunit of the APT subcomplex of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPT1 |
YOL102C |
tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED1 |
YDR077W |
Major stress-induced structural GPI-cell wall glycoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POX1 |
YGL205W |
Fatty-acyl coenzyme A oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE10 |
YGL228W |
Protein involved in outer spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL230C |
YGL230C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGT1 |
YKL038W |
Glucose-responsive transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBT1 |
YLL048C |
Transporter of the ATP-binding cassette (ABC) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIL1 |
YOL031C |
Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIR2 |
YOR010C |
Putative cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UIP4 |
YPL186C |
Protein that interacts with Ulp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR127W |
YPR127W |
Putative pyridoxine 4-dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS1 |
YNL192W |
Chitin synthase I |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IRA1 |
YBR140C |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG39 |
YLR312C |
Transmembrane receptor with a role in nucleophagy |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRF1 |
YGR246C |
TFIIIB B-related factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AMD1 |
YML035C |
AMP deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATS1 |
YAL020C |
Protein required for modification of wobble nucleosides in tRNA |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NRG2 |
YBR066C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST6 |
YML019W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNK1 |
YKL171W |
Protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AZF1 |
YOR113W |
Zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFG5 |
YMR238W |
Putative mannosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CST26 |
YBR042C |
Acyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HYR1 |
YIR037W |
Glutathione peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AHK1 |
YDL073W |
Scaffold protein in the HKR1 sub-branch of the Hog1p-signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUT1 |
YPL244C |
Protein with a role in UDP-galactose transport to the Golgi lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMD4 |
YLR363C |
Protein that may be involved in nonsense-mediated mRNA decay |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS1 |
YDR096W |
Histone demethylase and transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KRE9 |
YJL174W |
Glycoprotein involved in cell wall beta-glucan assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AMD2 |
YDR242W |
Putative amidase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DSC3 |
YOR223W |
Subunit of the DSC ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IGO2 |
YHR132W-A |
Protein required for initiation of G0 program |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| EMC3 |
YKL207W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIT3 |
YPR001W |
Dual specificity mitochondrial citrate and methylcitrate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IZH1 |
YDR492W |
Membrane protein involved in zinc ion homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDA2 |
YLR308W |
Chitin deacetylase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
