Standard name Systematic name Name description Description
YPK1 YKL126W S/T protein kinase S/T protein kinase; required for PM lipid and protein homeostasis; involved in sphingolipid-mediated and cell integrity signaling pathways and endocytosis; phosphorylates and downregulates Fpk1p; phosphorylates and inactivates Orm1p/2p when sphingolipid synthesis is compromised; role in TORC1/2-dependent Rps6a/b phosphorylation; phosphorylated and activated by TORC2 and by Pkh1/2p in the presence of phytosphingosine; human homolog SGK1 complements the null and inviability of a ypk1 ypk2 mutant
Visualize the interactome of YPK1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.241 0.348 0.270
Cytoplasm 0.988 0.970 0.966

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 2950

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
YPK1 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 5 3 5 Co-fractionation, Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Biochemical Activity
YPK2 YMR104C AGC-type S/T protein kinase genetic 5 3 5 Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement
FPK1 YNR047W Ser/Thr protein kinase genetic 5 3 4 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Dosage Growth Defect, Phenotypic Suppression
FPK1 YNR047W Ser/Thr protein kinase physical 5 1 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 4 3 4 Synthetic Lethality, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 3 3 3 Dosage Growth Defect, Phenotypic Suppression, Synthetic Rescue
YSP2 YDR326C Sterol-binding protein genetic 3 3 3 Dosage Growth Defect, Phenotypic Suppression, Synthetic Growth Defect
PKC1 YBL105C Protein serine/threonine kinase genetic 3 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Suppression
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 3 1 3 Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression
PLB1 YMR008C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 3 3 2 Dosage Rescue, Phenotypic Suppression, Synthetic Growth Defect
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 3 2 2 Negative Genetic, Dosage Lethality, Dosage Lethality
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit regulation 3 3 1 co-immunoprecipitation evidence, protein kinase assay evidence, two-dimensional polyacrylamide gel electrophoresis evidence
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
CNB1 YKL190W Calcineurin B genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 2 2 2 Co-fractionation, Biochemical Activity
CBS1 YDL069C Mitochondrial translational activator of the COB mRNA genetic 2 2 2 Phenotypic Suppression, Phenotypic Enhancement
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 2 2 2 Dosage Growth Defect, Phenotypic Suppression
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase physical 2 1 2 Biochemical Activity, Biochemical Activity
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 2 1 2 Biochemical Activity, Biochemical Activity
PKH1 YDR490C Serine/threonine protein kinase physical 2 1 2 Biochemical Activity, Biochemical Activity
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
ORM2 YLR350W Protein that mediates sphingolipid homeostasis physical 2 1 2 Biochemical Activity, Biochemical Activity
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) physical 2 1 2 Biochemical Activity, Biochemical Activity
YSP2 YDR326C Sterol-binding protein physical 2 1 2 Biochemical Activity, Biochemical Activity
MSS51 YLR203C Specific translational activator for the mitochondrial COX1 mRNA genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
DNF1 YER166W Aminophospholipid translocase (flippase) genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel physical 2 1 2 Biochemical Activity, Biochemical Activity
ORM1 YGR038W Protein that mediates sphingolipid homeostasis physical 2 1 2 Biochemical Activity, Biochemical Activity
DNF2 YDR093W Aminophospholipid translocase (flippase) genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
DNF3 YMR162C Trans-golgi network aminophospholipid translocase (flippase) genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) regulation 2 2 1 protein kinase assay evidence, qualitative western immunoblotting evidence
YSP2 YDR326C Sterol-binding protein regulation 2 2 1 protein kinase assay evidence, qualitative western immunoblotting evidence
PKH2 YOL100W Serine/threonine protein kinase genetic 2 2 1 Synthetic Growth Defect, Synthetic Rescue
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
MID1 YNL291C Stretch-activated Ca2+-permeable cation channel genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TOR2 YKL203C PIK-related protein kinase and rapamycin target regulation 1 1 1 protein kinase assay evidence
CUP2 YGL166W Copper-binding transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit regulation 1 1 1 protein kinase assay evidence
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit regulation 1 1 1 protein kinase assay evidence
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER regulation 1 1 1 protein kinase assay evidence
YPK1 YKL126W S/T protein kinase regulation 1 1 1 protein kinase assay evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Positive Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Synthetic Lethality
SRB4 YER022W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Rescue
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 PCA
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Phenotypic Suppression
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 PCA
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Synthetic Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Proximity Label-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Dosage Lethality
AVO1 YOL078W Component of the membrane-bound TORC2 complex physical 1 1 1 Affinity Capture-MS
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Synthetic Rescue
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Dosage Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Phenotypic Suppression
HER1 YOR227W Protein of unknown function physical 1 1 1 Biochemical Activity
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Dosage Growth Defect
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase physical 1 1 1 Biochemical Activity
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Dosage Growth Defect
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase physical 1 1 1 Affinity Capture-MS
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
TIF5 YPR041W Translation initiation factor eIF5 physical 1 1 1 Affinity Capture-MS
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Synthetic Growth Defect
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Phenotypic Suppression
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Dosage Rescue
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
SPS1 YDR523C STE20-family GCKIII protein kinase physical 1 1 1 Reconstituted Complex
KIN1 YDR122W S/T protein kinase genetic 1 1 1 Dosage Growth Defect
SAC6 YDR129C Fimbrin, actin-bundling protein physical 1 1 1 Affinity Capture-MS
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase genetic 1 1 1 Dosage Growth Defect
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division physical 1 1 1 Affinity Capture-MS
LAF1 YMR102C Sterol-binding beta-propeller protein genetic 1 1 1 Phenotypic Suppression
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase physical 1 1 1 Reconstituted Complex
GIS4 YML006C CAAX box containing protein of unknown function physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
SEG1 YMR086W Component of eisosome required for proper eisosome assembly genetic 1 1 1 Dosage Growth Defect
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Dosage Rescue
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Synthetic Growth Defect
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Phenotypic Suppression
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Reconstituted Complex
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) physical 1 1 1 Affinity Capture-MS
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 1 1 1 Dosage Growth Defect
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Synthetic Rescue
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall genetic 1 1 1 Dosage Rescue
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
LAC1 YKL008C Ceramide synthase component physical 1 1 1 Biochemical Activity
LAC1 YKL008C Ceramide synthase component genetic 1 1 1 Dosage Growth Defect
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Synthetic Rescue
JSN1 YJR091C Member of the Puf family of RNA-binding proteins physical 1 1 1 Biochemical Activity
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Affinity Capture-MS
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p genetic 1 1 1 Synthetic Rescue
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis genetic 1 1 1 Dosage Growth Defect
NFI1 YOR156C SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Dosage Growth Defect
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Suppression
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 1 1 1 Dosage Rescue
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Synthetic Lethality
MOB1 YIL106W Component of the mitotic exit network physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SIP3 YNL257C Putative sterol transfer protein genetic 1 1 1 Phenotypic Suppression
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Dosage Rescue
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
MCA1 YOR197W Ca2+-dependent cysteine protease physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
CCH1 YGR217W Voltage-gated high-affinity calcium channel physical 1 1 1 Biochemical Activity
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Synthetic Growth Defect
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) physical 1 1 1 Affinity Capture-RNA
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Synthetic Rescue
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p genetic 1 1 1 Synthetic Rescue
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Phenotypic Enhancement
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Dosage Growth Defect
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Synthetic Growth Defect
LAM1 YHR155W Putative sterol transfer protein genetic 1 1 1 Phenotypic Suppression
YPK2 YMR104C AGC-type S/T protein kinase physical 1 1 1 Affinity Capture-MS
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Dosage Growth Defect
LEU9 YOR108W Alpha-isopropylmalate synthase II (2-isopropylmalate synthase) physical 1 1 1 Affinity Capture-MS
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 1 1 1 Reconstituted Complex
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Dosage Rescue
PAL2 YHR097C Protein involved in clathrin-mediated endocytosis physical 1 1 1 Biochemical Activity
PAL2 YHR097C Protein involved in clathrin-mediated endocytosis genetic 1 1 1 Dosage Growth Defect
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
ATG21 YPL100W Phosphoinositide binding protein physical 1 1 1 Biochemical Activity
ATG21 YPL100W Phosphoinositide binding protein genetic 1 1 1 Dosage Growth Defect
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Dosage Growth Defect
KIN82 YCR091W Putative serine/threonine protein kinase genetic 1 1 1 Synthetic Rescue
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Suppression
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
DGR2 YKL121W Protein of unknown function genetic 1 1 1 Phenotypic Suppression
LAG1 YHL003C Ceramide synthase component physical 1 1 1 Biochemical Activity
LAG1 YHL003C Ceramide synthase component genetic 1 1 1 Dosage Growth Defect
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Biochemical Activity
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
PEX31 YGR004W Peroxisomal integral membrane protein physical 1 1 1 Biochemical Activity
PEX31 YGR004W Peroxisomal integral membrane protein genetic 1 1 1 Dosage Growth Defect
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Dosage Rescue
NPR1 YNL183C Protein kinase genetic 1 1 1 Dosage Growth Defect
GOT1 YMR292W Homodimeric protein that is packaged into COPII vesicles genetic 1 1 1 Dosage Rescue
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 1 1 1 Dosage Rescue
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 1 1 1 Dosage Rescue
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 1 1 1 Dosage Rescue
LCB3 YJL134W Long-chain base-1-phosphate phosphatase physical 1 1 1 Biochemical Activity
ISC1 YER019W Inositol phosphosphingolipid phospholipase C physical 1 1 1 Affinity Capture-Western
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Phenotypic Suppression
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER physical 1 1 1 Biochemical Activity
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER genetic 1 1 1 Phenotypic Suppression
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Dosage Rescue
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase physical 1 1 1 Biochemical Activity
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Synthetic Lethality
PMP1 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p physical 1 1 1 Affinity Capture-RNA
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 1 1 1 Affinity Capture-MS
CTS2 YDR371W Putative chitinase genetic 1 1 1 Dosage Rescue
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Phenotypic Suppression
YNR014W YNR014W Putative protein of unknown function physical 1 1 1 Biochemical Activity
YNR014W YNR014W Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
SMP1 YBR182C MADS-box transcription factor involved in osmotic stress response physical 1 1 1 Biochemical Activity
SMP1 YBR182C MADS-box transcription factor involved in osmotic stress response genetic 1 1 1 Dosage Rescue
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Phenotypic Suppression
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Dosage Rescue
SLI1 YGR212W N-acetyltransferase genetic 1 1 1 Dosage Rescue