Standard name Systematic name Name description Description
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing Protein with WD-40 repeats involved in rRNA processing; associates with rDNA chromatin in H4-tail-dependent manner; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily
Visualize the interactome of PWP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.079 0.055 NaN
Nucleolus 0.714 0.855 0.491
Nucleus 0.085 0.082 NaN
Vac/Vac Memb 0.185 0.087 0.339
Golgi NaN NaN 0.272

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleolus, nucleus 43800

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PWP1 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BRX1 YOL077C Nucleolar protein physical 4 3 4 Affinity Capture-MS, Affinity Capture-MS, PCA, Two-hybrid
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BRX1 YOL077C Nucleolar protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 2 2 2 Affinity Capture-MS, PCA
NOC2 YOR206W Protein involved in ribosome biogenesis physical 2 2 2 Affinity Capture-MS, PCA
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 2 2 2 Affinity Capture-MS, Protein-peptide
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NAN1 YPL126W U3 snoRNP protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CIC1 YHR052W Essential protein that interacts with proteasome components physical 2 1 2 PCA, PCA
SMC1 YFL008W Subunit of the multiprotein cohesin complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TYW1 YPL207W Iron-sulfur protein required for synthesis of wybutosine modified tRNA physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 2 Negative Genetic, Negative Genetic
HHF1 YBR009C Histone H4 genetic 2 1 2 Negative Genetic, Negative Genetic
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 2 2 1 Positive Genetic, Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 2 2 1 Negative Genetic, Positive Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 2 2 1 Negative Genetic, Positive Genetic
FCF1 YDR339C PINc domain endonuclease genetic 2 2 1 Negative Genetic, Positive Genetic
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly genetic 1 1 1 Negative Genetic
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 PCA
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase physical 1 1 1 PCA
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 1 1 1 PCA
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family physical 1 1 1 PCA
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 1 1 1 Affinity Capture-MS
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 PCA
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Positive Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Positive Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Growth Defect
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 1 1 1 Affinity Capture-Western
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Affinity Capture-MS
RPL15B YMR121C Ribosomal 60S subunit protein L15B physical 1 1 1 Affinity Capture-MS
RPS22B YLR367W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Affinity Capture-MS
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 1 1 1 Affinity Capture-MS
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 PCA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 PCA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins genetic 1 1 1 Negative Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 PCA
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Negative Genetic
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Affinity Capture-MS
SSF1 YHR066W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-Western
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RRP43 YCR035C Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
SLS1 YLR139C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Positive Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Positive Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Positive Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Positive Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
RPH1 YER169W JmjC domain-containing histone demethylase genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
RMR1 YGL250W Protein required for meiotic recombination and gene conversion genetic 1 1 1 Negative Genetic
YIL134C-A YIL134C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
YJL077W-B YJL077W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
YMR030W-A YMR030W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
YPL119C-A YPL119C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Positive Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Positive Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Positive Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
TMA22 YJR014W Protein of unknown function genetic 1 1 1 Positive Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
YKR011C YKR011C Protein of unknown function genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Positive Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
SCP1 YOR367W Component of yeast cortical actin cytoskeleton genetic 1 1 1 Positive Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
RTC6 YPL183W-A Protein involved in translation genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Negative Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-Western
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 1 1 1 Affinity Capture-MS
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) physical 1 1 1 Affinity Capture-MS
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Synthetic Lethality
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) physical 1 1 1 PCA
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
CIA2 YHR122W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Affinity Capture-MS
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Positive Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Positive Genetic
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Affinity Capture-MS
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex physical 1 1 1 Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Positive Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 PCA
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
HRK1 YOR267C Protein kinase physical 1 1 1 Affinity Capture-MS
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Positive Genetic
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
CDC53 YDL132W Cullin genetic 1 1 1 Negative Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Positive Genetic
CAF120 YNL278W Part of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Positive Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
ELA1 YNL230C Elongin A physical 1 1 1 Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
HEM15 YOR176W Ferrochelatase physical 1 1 1 Affinity Capture-MS
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription physical 1 1 1 Affinity Capture-MS
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Positive Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Affinity Capture-MS
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Positive Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
MSN5 YDR335W Karyopherin genetic 1 1 1 Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Positive Genetic
DSE3 YOR264W Daughter cell-specific protein, may help establish daughter fate genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease physical 1 1 1 Affinity Capture-MS
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p genetic 1 1 1 Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 Affinity Capture-MS
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Negative Genetic
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) physical 1 1 1 Affinity Capture-MS
DBP6 YNR038W Essential protein involved in ribosome biogenesis physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
ASN2 YGR124W Asparagine synthetase physical 1 1 1 Affinity Capture-MS
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
FRK1 YPL141C Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Positive Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
PKH3 YDR466W Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p physical 1 1 1 Affinity Capture-MS
LDB18 YLL049W Component of the dynactin complex genetic 1 1 1 Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Positive Genetic
GPC1 YGR149W Glycerophosphocholine acyltransferase (GPCAT) genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
ALK2 YBL009W Atypical protein kinase physical 1 1 1 Affinity Capture-MS
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Positive Genetic
PES4 YFR023W Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation genetic 1 1 1 Negative Genetic