| SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
physical |
30 |
7 |
24 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-localization, Two-hybrid, Co-localization, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Co-localization, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-purification, Affinity Capture-Western, Far Western, Reconstituted Complex |
| HHT1 |
YBR010W |
Histone H3 |
physical |
17 |
3 |
14 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Protein-peptide, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex |
| HHF1 |
YBR009C |
Histone H4 |
physical |
16 |
4 |
13 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Protein-peptide, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Reconstituted Complex |
| HHT2 |
YNL031C |
Histone H3 |
physical |
13 |
3 |
11 |
Reconstituted Complex, Reconstituted Complex, Protein-peptide, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
physical |
12 |
4 |
8 |
Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Co-crystal Structure |
| SIR3 |
YLR442C |
Silencing protein |
physical |
11 |
5 |
10 |
Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-fractionation, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
physical |
11 |
5 |
9 |
Affinity Capture-Western, Affinity Capture-Western, Co-localization, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| HHF2 |
YNL030W |
Histone H4 |
physical |
11 |
4 |
9 |
Reconstituted Complex, Protein-peptide, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex |
| SIR1 |
YKR101W |
Protein involved in silencing at mating-type loci HML and HMR |
genetic |
9 |
4 |
9 |
Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect, Dosage Rescue, Phenotypic Enhancement, Phenotypic Suppression |
| SIR1 |
YKR101W |
Protein involved in silencing at mating-type loci HML and HMR |
physical |
6 |
4 |
5 |
Affinity Capture-MS, Co-localization, Co-localization, Two-hybrid, Two-hybrid, Reconstituted Complex |
| SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
genetic |
5 |
3 |
5 |
Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Dosage Rescue, Phenotypic Suppression |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
5 |
2 |
5 |
Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
4 |
3 |
4 |
Dosage Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression |
| HHT1 |
YBR010W |
Histone H3 |
genetic |
4 |
3 |
3 |
Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue, Synthetic Rescue |
| HHT2 |
YNL031C |
Histone H3 |
genetic |
4 |
3 |
3 |
Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue, Synthetic Rescue |
| RAD7 |
YJR052W |
Nucleotide excision repair (NER) protein |
physical |
4 |
2 |
3 |
Two-hybrid, Reconstituted Complex, Two-hybrid, Two-hybrid |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
3 |
3 |
3 |
Phenotypic Enhancement, Synthetic Rescue, Phenotypic Suppression |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
3 |
3 |
3 |
Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
3 |
2 |
3 |
Dosage Rescue, Synthetic Rescue, Synthetic Rescue |
| HTA1 |
YDR225W |
Histone H2A |
physical |
3 |
1 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
3 |
1 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
| HTB1 |
YDR224C |
Histone H2B |
physical |
3 |
1 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
3 |
1 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
3 |
2 |
2 |
Reconstituted Complex, Biochemical Activity, Biochemical Activity |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
3 |
2 |
1 |
Reconstituted Complex, Reconstituted Complex, Far Western |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
| HHF1 |
YBR009C |
Histone H4 |
genetic |
2 |
2 |
2 |
Dosage Lethality, Synthetic Rescue |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Synthetic Rescue |
| HTB1 |
YDR224C |
Histone H2B |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
| SAN1 |
YDR143C |
Ubiquitin-protein ligase |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| MCM10 |
YIL150C |
Essential chromatin-associated protein |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| SAS2 |
YMR127C |
Histone acetyltransferase (HAT) catalytic subunit of the SAS complex |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
| ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| SER3 |
YER081W |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| SER1 |
YOR184W |
3-phosphoserine aminotransferase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ADI1 |
YMR009W |
Acireductone dioxygenease involved in methionine salvage pathway |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MET14 |
YKL001C |
Adenylylsulfate kinase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| AGA2 |
YGL032C |
Adhesion subunit of a-agglutinin of a-cells |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YPC1 |
YBR183W |
Alkaline ceramidase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CAR1 |
YPL111W |
Arginase, catabolizes arginine to ornithine and urea |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ARO9 |
YHR137W |
Aromatic aminotransferase II |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| BAR1 |
YIL015W |
Aspartyl protease secreted to periplasmic space of mating type a cell |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MET3 |
YJR010W |
ATP sulfurylase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| SUN4 |
YNL066W |
Cell wall protein related to glucanases localized in birth scars |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MHF2 |
YDL160C-A |
Component of the heterotetrameric MHF histone-fold complex |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| TOS1 |
YBR162C |
Covalently-bound cell wall protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CYB5 |
YNL111C |
Cytochrome b5 |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CYT1 |
YOR065W |
Cytochrome c1 |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CYC1 |
YJR048W |
Cytochrome c, isoform 1 |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CYC7 |
YEL039C |
Cytochrome c isoform 2, expressed under hypoxic conditions |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COA2 |
YPL189C-A |
Cytochrome oxidase assembly factor |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HUA2 |
YOR284W |
Cytoplasmic protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| GPP2 |
YER062C |
DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| RDH54 |
YBR073W |
DNA-dependent ATPase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| NEJ1 |
YLR265C |
DNA end-binding protein required for nonhomologous end joining (NHEJ) |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YNL337W |
YNL337W |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YCL076W |
YCL076W |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YFL063W |
YFL063W |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YCR097W-A |
YCR097W-A |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YCL065W |
YCL065W |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YGR182C |
YGR182C |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COS1 |
YNL336W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COS4 |
YFL062W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COS8 |
YHL048W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YNR064C |
YNR064C |
Epoxide hydrolase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HMX1 |
YLR205C |
ER localized heme oxygenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| STE14 |
YDR410C |
Farnesyl cysteine-carboxyl methyltransferase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| STE4 |
YOR212W |
G protein beta subunit |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| STE18 |
YJR086W |
G protein gamma subunit |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| AXL1 |
YPR122W |
Haploid specific endoprotease of a-factor mating pheromone |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YGL193C |
YGL193C |
Haploid-specific gene repressed by a1-alpha2 |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HPF1 |
YOL155C |
Haze-protective mannoprotein |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MMP1 |
YLL061W |
High-affinity S-methylmethionine permease |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MPC3 |
YGR243W |
Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| IMD2 |
YHR216W |
Inosine monophosphate dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| AXL2 |
YIL140W |
Integral plasma membrane protein |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| BNA5 |
YLR231C |
Kynureninase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| BNA4 |
YBL098W |
Kynurenine 3-monooxygenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| DLD1 |
YDL174C |
Major mitochondrial D-lactate dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MFA2 |
YNL145W |
Mating pheromone a-factor |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MFA1 |
YDR461W |
Mating pheromone a-factor |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YLR460C |
YLR460C |
Member of the quinone oxidoreductase family |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| PAU4 |
YLR461W |
Member of the seripauperin multigene family |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HSP31 |
YDR533C |
Methylglyoxalase that converts methylglyoxal to D-lactate |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CRC1 |
YOR100C |
Mitochondrial inner membrane carnitine transporter |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MCR1 |
YKL150W |
Mitochondrial NADH-cytochrome b5 reductase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| PRX1 |
YBL064C |
Mitochondrial peroxiredoxin with thioredoxin peroxidase activity |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| SFC1 |
YJR095W |
Mitochondrial succinate-fumarate transporter |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| AMN1 |
YBR158W |
Modulator of cell separation and mitotic exit |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| IME4 |
YGL192W |
mRNA N6-adenosine methyltransferase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| DDR2 |
YOL052C-A |
Multi-stress response protein |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| FDH1 |
YOR388C |
NAD(+)-dependent formate dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ADH7 |
YCR105W |
NADPH-dependent medium chain alcohol dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YAR075W |
YAR075W |
Non-functional protein with homology IMP dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| IMD1 |
YAR073W |
Nonfunctional protein with homology to IMP dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| GTO3 |
YMR251W |
Omega class glutathione transferase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| PLN1 |
YKR046C |
Perilipin, involved in formation and stability of lipid droplets |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| VBA2 |
YBR293W |
Permease of basic amino acids in the vacuolar membrane |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| VBA3 |
YCL069W |
Permease of basic amino acids in the vacuolar membrane |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| STE5 |
YDR103W |
Pheromone-responsive MAPK scaffold protein |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ERG8 |
YMR220W |
Phosphomevalonate kinase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HSP12 |
YFL014W |
Plasma membrane protein involved in maintaining membrane organization |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| JID1 |
YPR061C |
Probable Hsp40p co-chaperone |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YDR018C |
YDR018C |
Probable membrane protein with three predicted transmembrane domains |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| PUT4 |
YOR348C |
Proline permease |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| NCA3 |
YJL116C |
Protein involved in mitochondrion organization |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| NSG2 |
YNL156C |
Protein involved in regulation of sterol biosynthesis |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| THI5 |
YFL058W |
Protein involved in synthesis of the thiamine precursor HMP |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YER053C-A |
YER053C-A |
Protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| SNO3 |
YFL060C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ICS2 |
YBR157C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ICY1 |
YMR195W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YKR075C |
YKR075C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CMC4 |
YMR194C-B |
Protein that localizes to the mitochondrial intermembrane space |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YPS5 |
YGL259W |
Protein with similarity to GPI-anchored aspartic proteases |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| GEX1 |
YCL073C |
Proton:glutathione antiporter |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| PDH1 |
YPR002W |
Putative 2-methylcitrate dehydratase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| AAD15 |
YOL165C |
Putative aryl-alcohol dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YBR284W |
YBR284W |
Putative metallo-dependent hydrolase superfamily protein |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| DPI8 |
YJL133C-A |
Putative mitochondrial protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YJL047C-A |
YJL047C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YCL068C |
YCL068C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YFR057W |
YFR057W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YGL258W-A |
YGL258W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YIL014C-A |
YIL014C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YDR042C |
YDR042C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YMR206W |
YMR206W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YPR027C |
YPR027C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YJR115W |
YJR115W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| STE2 |
YFL026W |
Receptor for alpha-factor pheromone |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YDR034C-D |
YDR034C-D |
Retrotransposon TYA Gag and TYB Pol genes |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| YDR170W-A |
YDR170W-A |
Retrotransposon TYA Gag gene |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| REX3 |
YLR107W |
RNA exonuclease |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HMRA1 |
YCR097W |
Silenced copy of a1 at HMR |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HMRA2 |
YCR096C |
Silenced copy of a2 at HMR |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HMLALPHA1 |
YCL066W |
Silenced copy of ALPHA1 at HML |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HMLALPHA2 |
YCL067C |
Silenced copy of ALPHA2 at HML |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HO |
YDL227C |
Site-specific endonuclease |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| RSB1 |
YOR049C |
Sphingoid long-chain base (LCB) efflux transporter |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| QCR6 |
YFR033C |
Subunit 6 of the ubiquinol cytochrome-c reductase complex |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| QCR7 |
YDR529C |
Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| QCR9 |
YGR183C |
Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| MET10 |
YFR030W |
Subunit alpha of assimilatory sulfite reductase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COX26 |
YDR119W-A |
Subunit of cytochrome C oxidase complex |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| GPA1 |
YHR005C |
Subunit of G protein involved in pheromone response |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| QCR10 |
YHR001W-A |
Subunit of the ubiqunol-cytochrome c oxidoreductase complex |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| HAP4 |
YKL109W |
Transcription factor |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ATG39 |
YLR312C |
Transmembrane receptor with a role in nucleophagy |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| TGL2 |
YDR058C |
Triacylglycerol lipase that is localized to the mitochondria |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| BNA2 |
YJR078W |
Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| UBX6 |
YJL048C |
UBX (ubiquitin regulatory X) domain-containing protein |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| RME1 |
YGR044C |
Zinc finger protein involved in control of meiosis |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| CAD1 |
YDR423C |
AP-1-like basic leucine zipper (bZIP) transcriptional activator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CYS4 |
YGR155W |
Cystathionine beta-synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
physical |
1 |
1 |
1 |
Co-localization |
| HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNR2 |
YJL026W |
Ribonucleotide-diphosphate reductase (RNR), small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SAH1 |
YER043C |
S-adenosyl-L-homocysteine hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ADH6 |
YMR318C |
NADPH-dependent medium chain alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CHZ1 |
YER030W |
Histone chaperone for Htz1p/H2A-H2B dimer |
physical |
1 |
1 |
1 |
Co-localization |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
physical |
1 |
1 |
1 |
Two-hybrid |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ZDS2 |
YML109W |
Protein with a role in regulating Swe1p-dependent polarized growth |
physical |
1 |
1 |
1 |
Two-hybrid |
| YLR278C |
YLR278C |
Zinc-cluster protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| TEL1 |
YBL088C |
Protein kinase primarily involved in telomere length regulation |
physical |
1 |
1 |
1 |
Two-hybrid |
| UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
physical |
1 |
1 |
1 |
Co-localization |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SAE2 |
YGL175C |
Endonuclease required for telomere elongation |
physical |
1 |
1 |
1 |
Two-hybrid |
| HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ARP5 |
YNL059C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ESC1 |
YMR219W |
Protein involved in telomeric silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
physical |
1 |
1 |
1 |
Co-localization |
| HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ASF2 |
YDL197C |
Anti-silencing protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
physical |
1 |
1 |
1 |
Two-hybrid |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
physical |
1 |
1 |
1 |
Two-hybrid |
| PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
