| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
14 |
4 |
10 |
Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
11 |
3 |
9 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue, Dosage Rescue, Synthetic Lethality |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
7 |
3 |
6 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
6 |
3 |
5 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Dosage Rescue |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| BNR1 |
YIL159W |
Formin |
physical |
4 |
2 |
2 |
Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Dosage Growth Defect, Negative Genetic |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| IMH1 |
YLR309C |
Protein involved in vesicular transport |
physical |
3 |
2 |
2 |
FRET, Two-hybrid, Two-hybrid |
| ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
physical |
3 |
2 |
2 |
FRET, Two-hybrid, Two-hybrid |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
physical |
3 |
1 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| BNI1 |
YNL271C |
Formin |
genetic |
3 |
3 |
1 |
Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Lethality |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-RNA |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
physical |
2 |
2 |
1 |
PCA, Two-hybrid |
| BNR1 |
YIL159W |
Formin |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Rescue |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
physical |
2 |
2 |
1 |
PCA, Two-hybrid |
| RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
| EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GON7 |
YJL184W |
Component of the EKC/KEOPS protein complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| ECM2 |
YBR065C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
physical |
1 |
1 |
1 |
Two-hybrid |
| RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
1 |
1 |
1 |
Two-hybrid |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Two-hybrid |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
| DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
physical |
1 |
1 |
1 |
Two-hybrid |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
physical |
1 |
1 |
1 |
Two-hybrid |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
physical |
1 |
1 |
1 |
Two-hybrid |
| MRPL24 |
YMR193W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL9 |
YGR220C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Two-hybrid |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
| SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
1 |
1 |
1 |
Two-hybrid |
| MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
| QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GYP5 |
YPL249C |
GTPase-activating protein (GAP) for yeast Rab family members |
physical |
1 |
1 |
1 |
Two-hybrid |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
physical |
1 |
1 |
1 |
Two-hybrid |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Two-hybrid |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| GZF3 |
YJL110C |
GATA zinc finger protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
physical |
1 |
1 |
1 |
Two-hybrid |
| NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
physical |
1 |
1 |
1 |
Two-hybrid |
| MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CHA4 |
YLR098C |
DNA binding transcriptional activator |
physical |
1 |
1 |
1 |
Two-hybrid |
| FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
PCA |
| NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SAC3 |
YDR159W |
mRNA export factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
physical |
1 |
1 |
1 |
Two-hybrid |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
physical |
1 |
1 |
1 |
Two-hybrid |
| NRG2 |
YBR066C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEA2 |
YER149C |
Coiled-coil 12S polarisome subunit |
physical |
1 |
1 |
1 |
Two-hybrid |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
physical |
1 |
1 |
1 |
Two-hybrid |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESC1 |
YMR219W |
Protein involved in telomeric silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC107 |
YJR021C |
Protein involved in early stages of meiotic recombination |
physical |
1 |
1 |
1 |
Two-hybrid |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
physical |
1 |
1 |
1 |
Two-hybrid |
| SCD5 |
YOR329C |
Protein required for normal actin organization and endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
| ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Two-hybrid |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDS5 |
YMR076C |
Cohesion maintenance factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| KIP1 |
YBL063W |
Kinesin-related motor protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| QDR3 |
YBR043C |
Multidrug transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
physical |
1 |
1 |
1 |
Two-hybrid |
| FMP27 |
YLR454W |
Protein with structural similarity to lipid transport protein Vps13p |
physical |
1 |
1 |
1 |
Two-hybrid |
| HSP26 |
YBR072W |
Small heat shock protein (sHSP) with chaperone activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSK3 |
YKL138C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
| NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| HOB2 |
YPR117W |
Protein with structural similarity to lipid transport protein Vps13p |
physical |
1 |
1 |
1 |
Two-hybrid |
| COA4 |
YLR218C |
Twin Cx(9)C protein involved in cytochrome c oxidase organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIL1 |
YOR304C-A |
Protein that binds Bud6p and has a role in actin cable assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
| RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK2 |
YPL203W |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
physical |
1 |
1 |
1 |
Two-hybrid |
| ZIP1 |
YDR285W |
Transverse filament protein of the synaptonemal complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| YET3 |
YDL072C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNX41 |
YDR425W |
Sorting nexin |
physical |
1 |
1 |
1 |
Two-hybrid |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Two-hybrid |
| VAB2 |
YEL005C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Two-hybrid |
| VFA1 |
YER128W |
Protein that interacts with Vps4p and has a role in vacuolar sorting |
physical |
1 |
1 |
1 |
Two-hybrid |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNX4 |
YJL036W |
Sorting nexin |
physical |
1 |
1 |
1 |
Two-hybrid |
| YKL050C |
YKL050C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPO14 |
YKR031C |
Phospholipase D |
physical |
1 |
1 |
1 |
Two-hybrid |
| STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Two-hybrid |
| VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| YVC1 |
YOR087W |
Vacuolar cation channel |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
physical |
1 |
1 |
1 |
Two-hybrid |
| SVL3 |
YPL032C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPP1 |
YPL138C |
Subunit of COMPASS (Set1C) |
physical |
1 |
1 |
1 |
Two-hybrid |
| YSP2 |
YDR326C |
Sterol-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
physical |
1 |
1 |
1 |
Two-hybrid |
| YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
physical |
1 |
1 |
1 |
Two-hybrid |
| YPL216W |
YPL216W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
physical |
1 |
1 |
1 |
Two-hybrid |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
physical |
1 |
1 |
1 |
Two-hybrid |
| TOP1 |
YOL006C |
Topoisomerase I |
physical |
1 |
1 |
1 |
Two-hybrid |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL012C |
YDL012C |
Tail-anchored plasma membrane protein with a conserved CYSTM module |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR248C |
YDR248C |
Putative gluconokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO74 |
YGL170C |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL036W |
YOL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO20 |
YMR017W |
Meiosis-specific subunit of the t-SNARE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTA12 |
YMR089C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWT1 |
YOR166C |
RNA endoribonuclease involved in perinuclear mRNP quality control |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC3 |
YLR066W |
Subunit of signal peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC98 |
YNL126W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OTU2 |
YHL013C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKP2 |
YGL059W |
Mitochondrial protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APE4 |
YHR113W |
Cytoplasmic aspartyl aminopeptidase with possible vacuole function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
physical |
1 |
1 |
1 |
Two-hybrid |
| FRT1 |
YOR324C |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
physical |
1 |
1 |
1 |
Two-hybrid |
| LAM4 |
YHR080C |
Sterol-binding protein that localizes to puncta in the cortical ER |
physical |
1 |
1 |
1 |
Two-hybrid |
| LNP1 |
YHR192W |
Lunapark family member involved in ER network formation |
physical |
1 |
1 |
1 |
Two-hybrid |
| FMP30 |
YPL103C |
Protein with a role in maintaining mitochondrial morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCA2 |
YPR155C |
Protein that regulates expression of Fo-F1 ATP synthase subunits |
physical |
1 |
1 |
1 |
Two-hybrid |
| RCF1 |
YML030W |
Cytochrome c oxidase subunit |
physical |
1 |
1 |
1 |
Two-hybrid |