Standard name Systematic name Name description Description
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins; plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate; human homolog PML implicated in promyelocytic leukemia can partially complement yeast null mutant
Visualize the interactome of ULP2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.956 0.909 0.959
Mito NaN 0.200 0.113

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 450

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ULP2 2 0 0 1 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 11 4 9 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue, Dosage Growth Defect, Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 11 3 6 Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 9 3 6 Synthetic Rescue, Synthetic Rescue, Dosage Lethality, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 8 3 5 Biochemical Activity, Protein-peptide, Biochemical Activity, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Protein-peptide, Reconstituted Complex
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease genetic 6 4 4 Synthetic Rescue, Synthetic Lethality, Phenotypic Suppression, Synthetic Rescue, Dosage Rescue, Synthetic Rescue
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I physical 6 4 3 Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
UBA2 YDR390C Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p genetic 6 3 3 Synthetic Rescue, Synthetic Rescue, Dosage Growth Defect, Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 3 3 3 Biochemical Activity, Affinity Capture-MS, Two-hybrid
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 3 2 3 Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 3 2 2 Phenotypic Suppression, Dosage Rescue, Dosage Rescue
TOP2 YNL088W Topoisomerase II genetic 3 2 2 Dosage Rescue, Synthetic Rescue, Dosage Rescue
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex physical 3 2 1 Two-hybrid, Two-hybrid, Affinity Capture-Western
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 2 2 2 PCA, Affinity Capture-MS
SSF1 YHR066W Constituent of 66S pre-ribosomal particles physical 2 2 2 PCA, Affinity Capture-MS
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 2 2 2 PCA, Affinity Capture-MS
CIC1 YHR052W Essential protein that interacts with proteasome components physical 2 2 2 PCA, Affinity Capture-MS
RLI1 YDR091C Essential Fe-S protein physical 2 2 2 PCA, Affinity Capture-MS
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 2 2 2 PCA, Affinity Capture-MS
RPB8 YOR224C RNA polymerase subunit ABC14.5 physical 2 2 2 PCA, Affinity Capture-MS
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 2 2 2 Synthetic Lethality, Synthetic Rescue
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 2 2 2 PCA, Affinity Capture-MS
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 2 2 2 PCA, Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Synthetic Rescue, Phenotypic Enhancement
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 2 2 2 Phenotypic Suppression, Dosage Rescue
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 2 2 2 PCA, Affinity Capture-MS
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 2 2 2 PCA, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 2 2 2 PCA, Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 2 2 2 PCA, Affinity Capture-MS
RPL18B YNL301C Ribosomal 60S subunit protein L18B physical 2 2 2 PCA, Affinity Capture-MS
RPL13A YDL082W Ribosomal 60S subunit protein L13A physical 2 2 2 PCA, Affinity Capture-MS
ALD6 YPL061W Cytosolic aldehyde dehydrogenase physical 2 2 2 PCA, Affinity Capture-MS
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit physical 2 2 2 PCA, Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
WHI5 YOR083W Repressor of G1 transcription genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
MSH2 YOL090W Protein that binds to DNA mismatches genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 2 2 1 Synthetic Lethality, Phenotypic Enhancement
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 2 2 1 Synthetic Lethality, Phenotypic Suppression
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 2 2 1 Synthetic Lethality, Phenotypic Suppression
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I genetic 2 2 1 Synthetic Rescue, Dosage Rescue
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation regulation 1 1 1 quantitative western immunoblotting evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription physical 1 1 1 Affinity Capture-MS
CTF3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p physical 1 1 1 Reconstituted Complex
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex physical 1 1 1 Reconstituted Complex
MTW1 YAL034W-A Essential component of the MIND kinetochore complex physical 1 1 1 PCA
NSL1 YPL233W Essential component of the MIND kinetochore complex physical 1 1 1 PCA
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex physical 1 1 1 Affinity Capture-MS
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Synthetic Rescue
BFR2 YDR299W Component of the SSU and 90S preribosomes physical 1 1 1 Affinity Capture-MS
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 1 1 1 PCA
BRX1 YOL077C Nucleolar protein physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 1 1 1 Affinity Capture-MS
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Affinity Capture-MS
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 1 1 1 Affinity Capture-MS
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
MAK16 YAL025C Essential nuclear protein physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOP2 YNL061W rRNA m5C methyltransferase physical 1 1 1 Affinity Capture-MS
NOP4 YPL043W Nucleolar protein physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
NSA1 YGL111W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 PCA
RPL32 YBL092W Ribosomal 60S subunit protein L32 physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
ADH1 YOL086C Alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
SMB1 YER029C Core Sm protein Sm B physical 1 1 1 Affinity Capture-MS
BRE1 YDL074C E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
NOC2 YOR206W Protein involved in ribosome biogenesis physical 1 1 1 Affinity Capture-MS
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
MCM21 YDR318W Component of the kinetochore sub-complex COMA physical 1 1 1 Reconstituted Complex
RRP14 YKL082C Essential protein, constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling physical 1 1 1 Affinity Capture-MS
PWP2 YCR057C Conserved 90S pre-ribosomal component physical 1 1 1 Affinity Capture-MS
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger physical 1 1 1 PCA
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly physical 1 1 1 Affinity Capture-MS
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 PCA
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 PCA
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Two-hybrid
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
RPA34 YJL148W RNA polymerase I subunit A34.5 physical 1 1 1 Affinity Capture-MS
RPC25 YKL144C RNA polymerase III subunit C25 physical 1 1 1 PCA
RPO31 YOR116C RNA polymerase III largest subunit C160 physical 1 1 1 Affinity Capture-MS
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 1 1 1 Synthetic Rescue
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 1 1 1 Affinity Capture-MS
RSC6 YCR052W Component of the RSC chromatin remodeling complex physical 1 1 1 PCA
SNP1 YIL061C Component of U1 snRNP required for mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-MS
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Phenotypic Enhancement
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-MS
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p physical 1 1 1 PCA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PUF6 YDR496C Pumilio-homology domain protein physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF physical 1 1 1 PCA
HGH1 YGR187C Chaperone protein for translation factor eEF2 physical 1 1 1 PCA
APL1 YJR005W Beta-adaptin physical 1 1 1 PCA
APL3 YBL037W Alpha-adaptin physical 1 1 1 Affinity Capture-MS
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 PCA
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Affinity Capture-MS
CAR1 YPL111W Arginase, catabolizes arginine to ornithine and urea physical 1 1 1 PCA
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Phenotypic Enhancement
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor physical 1 1 1 PCA
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 PCA
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
ENO1 YGR254W Enolase I, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Affinity Capture-MS
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly physical 1 1 1 Affinity Capture-MS
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) physical 1 1 1 PCA
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
MPP10 YJR002W Component of the SSU processome and 90S preribosome physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
FAP7 YDL166C Essential NTPase required for small ribosome subunit synthesis physical 1 1 1 PCA
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 PCA
MAK5 YBR142W Essential nucleolar protein physical 1 1 1 Affinity Capture-MS
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
MSH3 YCR092C Mismatch repair protein genetic 1 1 1 Synthetic Growth Defect
HTZ1 YOL012C Histone variant H2AZ physical 1 1 1 Affinity Capture-MS
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 1 1 1 Phenotypic Suppression
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase physical 1 1 1 Affinity Capture-MS
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 1 1 1 PCA
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Phenotypic Suppression
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 1 1 1 Affinity Capture-MS
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex physical 1 1 1 Affinity Capture-MS
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Affinity Capture-MS
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 1 1 1 Affinity Capture-MS
NOP14 YDL148C Nucleolar protein physical 1 1 1 Affinity Capture-MS
RAD51 YER095W Strand exchange protein genetic 1 1 1 Synthetic Lethality
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Lethality
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RPA12 YJR063W RNA polymerase I subunit A12.2 physical 1 1 1 PCA
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A physical 1 1 1 Affinity Capture-MS
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) physical 1 1 1 Affinity Capture-MS
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Synthetic Rescue
RPP2B YDR382W Ribosomal protein P2 beta physical 1 1 1 PCA
SKI6 YGR195W Exosome non-catalytic core component physical 1 1 1 PCA
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Affinity Capture-MS
PRP42 YDR235W U1 snRNP protein involved in splicing physical 1 1 1 Affinity Capture-MS
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA physical 1 1 1 Affinity Capture-MS
SPN1 YPR133C Protein involved in RNA polymerase II transcription physical 1 1 1 PCA
SRP21 YKL122C Subunit of the signal recognition particle (SRP) physical 1 1 1 Affinity Capture-MS
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase physical 1 1 1 PCA
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase physical 1 1 1 Affinity Capture-MS
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering physical 1 1 1 Affinity Capture-MS
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
TIF5 YPR041W Translation initiation factor eIF5 physical 1 1 1 PCA
TPD3 YAL016W Regulatory subunit A of the heterotrimeric PP2A complex physical 1 1 1 PCA
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Lethality
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
RRP12 YPL012W Protein required for export of the ribosomal subunits physical 1 1 1 Affinity Capture-MS
ROK1 YGL171W RNA-dependent ATPase physical 1 1 1 Affinity Capture-MS
LAP2 YNL045W Leucyl aminopeptidase yscIV with epoxide hydrolase activity physical 1 1 1 Affinity Capture-MS
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
TRM112 YNR046W Protein involved in methylation of tRNA, rRNA, and translation factors physical 1 1 1 PCA
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Growth Defect
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization physical 1 1 1 Affinity Capture-MS
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 1 1 1 PCA
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) physical 1 1 1 PCA
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Dosage Growth Defect
AHP1 YLR109W Thiol-specific peroxiredoxin physical 1 1 1 PCA
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 Affinity Capture-MS
ARO4 YBR249C 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase physical 1 1 1 PCA
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism physical 1 1 1 PCA
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) physical 1 1 1 PCA
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
HEF3 YNL014W Translational elongation factor EF-3 physical 1 1 1 Affinity Capture-MS
RNQ1 YCL028W [PIN(+)] prion physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
SUV3 YPL029W ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase physical 1 1 1 PCA
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Lethality
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
TMA19 YKL056C Protein that associates with ribosomes physical 1 1 1 PCA
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Phenotypic Enhancement
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Phenotypic Suppression
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 PCA
ATG20 YDL113C Sorting nexin family member physical 1 1 1 Affinity Capture-MS
NOP13 YNL175C Nucleolar protein found in preribosomal complexes physical 1 1 1 Affinity Capture-MS
MSS116 YDR194C Mitochondrial transcription elongation factor physical 1 1 1 Affinity Capture-MS
UBA1 YKL210W Ubiquitin activating enzyme (E1) physical 1 1 1 PCA
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 Affinity Capture-MS
ADH6 YMR318C NADPH-dependent medium chain alcohol dehydrogenase physical 1 1 1 PCA
CYS3 YAL012W Cystathionine gamma-lyase physical 1 1 1 PCA
RRP3 YHR065C Protein involved in rRNA processing physical 1 1 1 Affinity Capture-MS
SKA1 YKL023W SKI complex-associated protein physical 1 1 1 Affinity Capture-MS
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation physical 1 1 1 Affinity Capture-MS
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Synthetic Growth Defect
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex physical 1 1 1 Reconstituted Complex
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 1 1 1 Synthetic Rescue
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Synthetic Growth Defect
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 PCA
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
SPB1 YCL054W AdoMet-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 Affinity Capture-MS
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 physical 1 1 1 PCA
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
NFI1 YOR156C SUMO E3 ligase genetic 1 1 1 Dosage Rescue
RPL9A YGL147C Ribosomal 60S subunit protein L9A physical 1 1 1 Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SMC2 YFR031C Subunit of the condensin complex genetic 1 1 1 Dosage Rescue
JIP5 YPR169W Protein required for biogenesis of the large ribosomal subunit physical 1 1 1 Affinity Capture-MS
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Phenotypic Suppression
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Synthetic Growth Defect
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 PCA
ELO3 YLR372W Elongase physical 1 1 1 PCA
HNT1 YDL125C Adenosine 5'-monophosphoramidase physical 1 1 1 PCA
SIZ1 YDR409W SUMO E3 ligase genetic 1 1 1 Dosage Rescue
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 physical 1 1 1 PCA
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
MBF1 YOR298C-A Transcriptional coactivator physical 1 1 1 PCA
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Phenotypic Suppression
DBP1 YPL119C ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
CMR2 YOR093C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
SAM2 YDR502C S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
NCP1 YHR042W NADP-cytochrome P450 reductase physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus physical 1 1 1 PCA
TCB1 YOR086C Lipid-binding ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 PCA
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
RPL28 YGL103W Ribosomal 60S subunit protein L28 physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
LEU1 YGL009C Isopropylmalate isomerase physical 1 1 1 Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL14B YHL001W Ribosomal 60S subunit protein L14B physical 1 1 1 Affinity Capture-MS
RPL19B YBL027W Ribosomal 60S subunit protein L19B physical 1 1 1 Affinity Capture-MS
RPL21A YBR191W Ribosomal 60S subunit protein L21A physical 1 1 1 Affinity Capture-MS
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Affinity Capture-MS
MHP1 YJL042W Microtubule-associated protein involved in microtubule organization physical 1 1 1 Affinity Capture-MS
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Dosage Rescue
HSP31 YDR533C Methylglyoxalase that converts methylglyoxal to D-lactate physical 1 1 1 PCA
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Phenotypic Suppression
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B physical 1 1 1 PCA
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor physical 1 1 1 Affinity Capture-MS
SRP14 YDL092W Signal recognition particle (SRP) subunit physical 1 1 1 Affinity Capture-MS
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit physical 1 1 1 PCA
SRP40 YKR092C Nucleolar serine-rich protein physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-MS
GUK1 YDR454C Guanylate kinase physical 1 1 1 PCA
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Dosage Rescue
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs physical 1 1 1 Affinity Capture-MS
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 1 1 1 PCA
NPT1 YOR209C Nicotinate phosphoribosyltransferase physical 1 1 1 PCA
PTH2 YBL057C One of two mitochondrially-localized peptidyl-tRNA hydrolases physical 1 1 1 PCA
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex physical 1 1 1 Affinity Capture-MS
RPL20A YMR242C Ribosomal 60S subunit protein L20A physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b physical 1 1 1 PCA
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL17B YJL177W Ribosomal 60S subunit protein L17B physical 1 1 1 PCA
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Affinity Capture-MS
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 1 1 1 Affinity Capture-MS
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase physical 1 1 1 PCA
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 PCA
RPL36A YMR194W Ribosomal 60S subunit protein L36A physical 1 1 1 Affinity Capture-MS
RPL26B YGR034W Ribosomal 60S subunit protein L26B physical 1 1 1 Affinity Capture-MS
RPL34A YER056C-A Ribosomal 60S subunit protein L34A physical 1 1 1 Affinity Capture-MS
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
DEG1 YFL001W tRNA:pseudouridine synthase physical 1 1 1 Affinity Capture-MS
MPD1 YOR288C Member of the protein disulfide isomerase (PDI) family physical 1 1 1 Affinity Capture-MS
RDL1 YOR285W Thiosulfate sulfurtransferase physical 1 1 1 PCA
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GRX3 YDR098C Glutathione-dependent oxidoreductase physical 1 1 1 PCA
INO1 YJL153C Inositol-3-phosphate synthase genetic 1 1 1 Dosage Rescue
SQT1 YIR012W Specific assembly chaperone for ribosomal protein Rpl10p physical 1 1 1 PCA
NNR2 YKL151C Widely-conserved NADHX dehydratase physical 1 1 1 Affinity Capture-MS
RMR1 YGL250W Protein required for meiotic recombination and gene conversion genetic 1 1 1 Dosage Rescue
SHB17 YKR043C Sedoheptulose bisphosphatase involved in riboneogenesis physical 1 1 1 PCA
GRX2 YDR513W Cytoplasmic glutaredoxin physical 1 1 1 PCA
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL12B YDR418W Ribosomal 60S subunit protein L12B physical 1 1 1 Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
NCE103 YNL036W Carbonic anhydrase physical 1 1 1 PCA
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ECM32 YER176W DNA dependent ATPase/DNA helicase physical 1 1 1 Affinity Capture-MS
MTQ1 YNL063W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 PCA
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway physical 1 1 1 PCA
SRP72 YPL210C Core component of the signal recognition particle (SRP) physical 1 1 1 Affinity Capture-MS
HMS2 YJR147W Protein with similarity to heat shock transcription factors physical 1 1 1 Affinity Capture-MS
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells physical 1 1 1 PCA
TRM82 YDR165W Noncatalytic subunit of a tRNA methyltransferase complex physical 1 1 1 PCA
YMR295C YMR295C Protein of unknown function that associates with ribosomes physical 1 1 1 PCA
YPL225W YPL225W Protein of unknown function physical 1 1 1 PCA
YDL085C-A YDL085C-A Putative protein of unknown function physical 1 1 1 PCA
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
URB1 YKL014C Protein required for the normal accumulation of 25S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP15 YMR093W Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
UTP6 YDR449C Nucleolar protein physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
YCR016W YCR016W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YDR210C-D YDR210C-D Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YER134C YER134C Magnesium-dependent acid phosphatase physical 1 1 1 Affinity Capture-MS
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
YLR419W YLR419W Putative helicase with limited sequence similarity to human Rb protein physical 1 1 1 Affinity Capture-MS
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-MS
TAD1 YGL243W tRNA-specific adenosine deaminase physical 1 1 1 Affinity Capture-MS
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage physical 1 1 1 Affinity Capture-MS