Standard name Systematic name Name description Description
CHS5 YLR330W Component of the exomer complex Component of the exomer complex; the exomer which also contains Csh6p, Bch1p, Bch2p, and Bud7, is involved in the export of select proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane; interacts selectively with the activated, GTP-bound form of Arf1p; Chs5p is the only protein with a BRCT domain that is not localized to the nucleus
Visualize the interactome of CHS5
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Golgi 0.110 0.394 0.681
Mito 0.906 0.806 0.440
Nucleolus 0.050 0.073 0.069
Peroxisome 0.060 NaN NaN
Cort. Patches NaN 0.055 0.095
Endosome NaN NaN 0.052
Vac/Vac Memb NaN NaN 0.086

GFP localization & abundance

GFP localization GFP abundance
late Golgi 172

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CHS5 1 1 1 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 11 3 7 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family physical 10 6 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Co-purification, Co-purification, Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 10 3 6 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 9 3 7 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 9 3 6 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 8 3 7 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 7 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
BCH1 YMR237W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) physical 6 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 6 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 6 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 6 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 5 3 4 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 5 3 4 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 5 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 5 2 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BUD7 YOR299W Member of the ChAPs family (Chs5p-Arf1p-binding proteins) physical 4 4 4 Affinity Capture-MS, Affinity Capture-Western, Co-purification, Two-hybrid
BNI1 YNL271C Formin genetic 4 3 4 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family physical 4 3 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification
CCW12 YLR110C Cell wall mannoprotein genetic 4 3 4 Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ARF1 YDL192W ADP-ribosylation factor physical 4 4 3 Co-purification, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 4 3 3 Synthetic Lethality, Positive Genetic, Positive Genetic, Synthetic Growth Defect
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
THR4 YCR053W Threonine synthase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARO7 YPR060C Chorismate mutase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHS3 YBR023C Chitin synthase III physical 3 3 3 Affinity Capture-Western, Reconstituted Complex, PCA
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
CHS5 YLR330W Component of the exomer complex physical 3 2 3 PCA, PCA, Co-crystal Structure
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 3 2 3 Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
FUS1 YCL027W Membrane protein localized to the shmoo tip physical 3 3 2 Co-localization, Two-hybrid, Affinity Capture-Western
SPA2 YLL021W Component of the polarisome genetic 3 3 2 Phenotypic Enhancement, Synthetic Growth Defect, Dosage Rescue
PFY1 YOR122C Profilin genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NRG1 YDR043C Transcriptional repressor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PRR1 YKL116C Serine/threonine protein kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HSP150 YJL159W O-mannosylated heat shock protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BBC1 YJL020C Protein possibly involved in assembly of actin patches genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
PEX14 YGL153W Central component of the peroxisomal importomer complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SEC22 YLR268W R-SNARE protein genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
VAN1 YML115C Component of the mannan polymerase I genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
FUS2 YMR232W Cell fusion regulator genetic 2 2 2 Dosage Rescue, Phenotypic Enhancement
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
BRE1 YDL074C E3 ubiquitin ligase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 2 1 2 Negative Genetic, Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BUD14 YAR014C Protein involved in bud-site selection genetic 2 1 2 Negative Genetic, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 2 1 2 Negative Genetic, Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CMD1 YBR109C Calmodulin genetic 2 1 2 Negative Genetic, Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
VPS3 YDR495C Component of CORVET membrane tethering complex genetic 2 1 2 Negative Genetic, Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 2 1 2 Negative Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Negative Genetic, Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 2 1 2 Negative Genetic, Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 2 1 2 Negative Genetic, Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 2 1 2 Negative Genetic, Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 2 1 2 Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 2 1 2 Negative Genetic, Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 2 1 2 Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 2 1 2 Negative Genetic, Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 2 1 2 Negative Genetic, Negative Genetic
YPT7 YML001W Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 2 1 2 Negative Genetic, Negative Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 2 1 2 Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 2 1 2 Negative Genetic, Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 2 1 2 Positive Genetic, Positive Genetic
SYH1 YPL105C Protein of unknown function that influences nuclear pore distribution genetic 2 1 2 Negative Genetic, Negative Genetic
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 2 1 2 Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 2 1 2 Negative Genetic, Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 2 1 2 Negative Genetic, Negative Genetic
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 2 1 2 Dosage Rescue, Dosage Rescue
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PAU24 YBR301W Cell wall mannoprotein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CLB3 YDL155W B-type cyclin involved in cell cycle progression genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
YDL206W YDL206W Putative protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SHE9 YDR393W Protein required for normal mitochondrial morphology genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MRX20 YFR045W Putative mitochondrial transport protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
YGL081W YGL081W Putative protein of unknown function genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
UBI4 YLL039C Ubiquitin genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
COQ2 YNR041C Para hydroxybenzoate polyprenyl transferase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
COX11 YPL132W Protein required for delivery of copper to Cox1p genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
LEA1 YPL213W Component of U2 snRNP complex genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 2 1 2 Negative Genetic, Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 2 1 2 Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 2 1 2 Negative Genetic, Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 2 1 2 Positive Genetic, Positive Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 2 1 2 Positive Genetic, Positive Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 1 2 Negative Genetic, Negative Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 2 2 1 Synthetic Rescue, Dosage Growth Defect
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 2 2 1 Phenotypic Suppression, Dosage Growth Defect
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking genetic 2 2 1 Synthetic Rescue, Dosage Rescue
SBE2 YDR351W Protein required for bud growth genetic 2 2 1 Synthetic Growth Defect, Dosage Rescue
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Negative Genetic, Negative Genetic
APL1 YJR005W Beta-adaptin genetic 2 1 1 Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 2 1 1 Positive Genetic, Positive Genetic
GET1 YGL020C Subunit of the GET complex genetic 2 1 1 Positive Genetic, Positive Genetic
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p genetic 2 1 1 Negative Genetic, Negative Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 2 1 1 Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 2 1 1 Negative Genetic, Negative Genetic
SOV1 YMR066W Mitochondrial protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SUP35 YDR172W Translation termination factor eRF3 genetic 2 1 1 Positive Genetic, Positive Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 1 Negative Genetic, Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BRF1 YGR246C TFIIIB B-related factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Positive Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex physical 1 1 1 Affinity Capture-Western
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex genetic 1 1 1 Phenotypic Suppression
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex physical 1 1 1 PCA
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-Western
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Phenotypic Suppression
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Positive Genetic
AIM41 YOR215C Protein of unknown function genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Synthetic Rescue
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
APL4 YPR029C Gamma-adaptin physical 1 1 1 PCA
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Positive Genetic
FUS1 YCL027W Membrane protein localized to the shmoo tip genetic 1 1 1 Dosage Rescue
SAC6 YDR129C Fimbrin, actin-bundling protein physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
LAP2 YNL045W Leucyl aminopeptidase yscIV with epoxide hydrolase activity physical 1 1 1 Affinity Capture-MS
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Synthetic Growth Defect
RPL1A YPL220W Ribosomal 60S subunit protein L1A physical 1 1 1 Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
PDS5 YMR076C Cohesion maintenance factor physical 1 1 1 Affinity Capture-MS
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Affinity Capture-MS
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi physical 1 1 1 Affinity Capture-Western
CLC1 YGR167W Clathrin light chain physical 1 1 1 Affinity Capture-Western
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Negative Genetic
FLC2 YAL053W Putative calcium channel involved in calcium release under hypotonic physical 1 1 1 PCA
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 PCA
DNF1 YER166W Aminophospholipid translocase (flippase) physical 1 1 1 PCA
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis physical 1 1 1 PCA
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis physical 1 1 1 PCA
LAA1 YJL207C AP-1 accessory protein physical 1 1 1 PCA
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Biochemical Activity
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
PIN2 YOR104W Exomer-dependent cargo protein physical 1 1 1 Reconstituted Complex
SKG6 YHR149C Integral membrane protein physical 1 1 1 Reconstituted Complex
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Co-localization
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RCR1 YBR005W Plasma membrane (PM) ubiquitin ligase-substrate adaptor physical 1 1 1 Two-hybrid
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking physical 1 1 1 PCA
MUP1 YGR055W High affinity methionine permease physical 1 1 1 PCA
CSR1 YLR380W Phosphatidylinositol transfer protein genetic 1 1 1 Dosage Rescue
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Dosage Rescue
YPT32 YGL210W Rab family GTPase involved in the exocytic pathway genetic 1 1 1 Dosage Rescue
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein genetic 1 1 1 Dosage Rescue
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 1 1 1 Negative Genetic
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
DYS1 YHR068W Deoxyhypusine synthase genetic 1 1 1 Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
PYC2 YBR218C Pyruvate carboxylase isoform genetic 1 1 1 Negative Genetic
RXT3 YDL076C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Positive Genetic
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Positive Genetic
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
SNX4 YJL036W Sorting nexin genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Positive Genetic
SRL3 YKR091W Repressor of transcription at Start genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
EMP24 YGL200C Component of the p24 complex genetic 1 1 1 Synthetic Growth Defect
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Synthetic Growth Defect
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Synthetic Growth Defect
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Negative Genetic
RAM2 YKL019W Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
CNE1 YAL058W Calnexin genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 1 1 1 Negative Genetic
ECM30 YLR436C Protein of unknown function genetic 1 1 1 Negative Genetic
DGA1 YOR245C Diacylglycerol acyltransferase genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Synthetic Growth Defect
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Positive Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Positive Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Positive Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Positive Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 1 1 1 Positive Genetic
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Positive Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Positive Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Positive Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Positive Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Negative Genetic
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
FMN1 YDR236C Riboflavin kinase, produces riboflavin monophosphate (FMN) genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TFC4 YGR047C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
LDB17 YDL146W Protein involved in the regulation of endocytosis genetic 1 1 1 Negative Genetic
MRPS28 YDR337W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Negative Genetic
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Negative Genetic
GPG1 YGL121C Proposed gamma subunit of the heterotrimeric G protein genetic 1 1 1 Negative Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
YGR035C YGR035C Putative protein of unknown function, potential Cdc28p substrate genetic 1 1 1 Negative Genetic
MEP1 YGR121C Ammonium permease genetic 1 1 1 Negative Genetic
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Negative Genetic
KEL2 YGR238C Protein that negatively regulates mitotic exit genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic
SSP1 YHR184W Protein involved in the control of meiotic nuclear division genetic 1 1 1 Negative Genetic
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Negative Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
MRPL8 YJL063C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL49 YJL096W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
SFC1 YJR095W Mitochondrial succinate-fumarate transporter genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
DCW1 YKL046C Putative mannosidase genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
TUM1 YOR251C Rhodanese domain sulfur transferase genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
MRPL19 YNL185C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
GSH2 YOL049W Glutathione synthetase genetic 1 1 1 Negative Genetic
DSC2 YOL073C Multi-transmembrane subunit of the DSC ubiquitin ligase complex genetic 1 1 1 Negative Genetic
YOR381W-A YOR381W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 1 1 1 Negative Genetic
MRPL51 YPR100W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
HAL1 YPR005C Cytoplasmic protein involved in halotolerance genetic 1 1 1 Dosage Rescue
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Synthetic Rescue
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Dosage Rescue
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Dosage Rescue
ENA1 YDR040C P-type ATPase sodium pump genetic 1 1 1 Dosage Rescue
QDR2 YIL121W Plasma membrane transporter of the major facilitator superfamily genetic 1 1 1 Dosage Rescue
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Phenotypic Enhancement
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin genetic 1 1 1 Synthetic Rescue
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Negative Genetic
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly physical 1 1 1 Co-crystal Structure
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Negative Genetic
AIM26 YKL037W Protein of unknown function genetic 1 1 1 Negative Genetic
ANY1 YMR010W Protein involved in phospholipid flippase function physical 1 1 1 PCA
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
AST2 YER101C Lipid raft associated protein genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic