| SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
physical |
9 |
3 |
9 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
physical |
8 |
3 |
8 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
physical |
8 |
5 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western |
| GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
physical |
7 |
4 |
7 |
Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-Western |
| SRB4 |
YER022W |
Subunit of the RNA polymerase II mediator complex |
physical |
7 |
2 |
7 |
Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
physical |
6 |
3 |
5 |
Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
physical |
5 |
3 |
5 |
Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Affinity Capture-MS |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
physical |
5 |
3 |
4 |
Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
physical |
4 |
2 |
4 |
Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| ROX3 |
YBL093C |
Subunit of the RNA polymerase II mediator complex |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS |
| SRB7 |
YDR308C |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
3 |
3 |
Two-hybrid, Co-purification, Affinity Capture-MS |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
physical |
3 |
2 |
3 |
Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
2 |
3 |
Co-purification, Co-purification, Affinity Capture-MS |
| SRB6 |
YBR253W |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
physical |
3 |
3 |
1 |
Two-hybrid, Reconstituted Complex, Biochemical Activity |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Far Western |
| HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Enhancement |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Reconstituted Complex |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Suppression |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| THP1 |
YOL072W |
Nuclear pore-associated protein |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
1 |
2 |
Co-purification, Co-purification |
| DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
physical |
2 |
2 |
1 |
PCA, Reconstituted Complex |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Growth Defect |
| GRR1 |
YJR090C |
F-box protein component of an SCF ubiquitin-ligase complex |
physical |
2 |
2 |
1 |
Reconstituted Complex, Two-hybrid |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| GAL4 |
YPL248C |
DNA-binding transcription factor required for activating GAL genes |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ASP3-1 |
YLR155C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ASP3-2 |
YLR157C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ASP3-3 |
YLR158C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ASP3-4 |
YLR160C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FRE1 |
YLR214W |
Ferric reductase and cupric reductase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FIT2 |
YOR382W |
Mannoprotein that is incorporated into the cell wall |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FIT3 |
YOR383C |
Mannoprotein that is incorporated into the cell wall |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HSP30 |
YCR021C |
Negative regulator of the H(+)-ATPase Pma1p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHO89 |
YBR296C |
Plasma membrane Na+/Pi cotransporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YLR162W |
YLR162W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RRT15 |
YLR162W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YLR159W |
YLR159W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YMR085W |
YMR085W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YLR035C-A |
YLR035C-A |
Retrotransposon TYA Gag and TYB Pol genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YOR192C-B |
YOR192C-B |
Retrotransposon TYA Gag and TYB Pol genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YMR046C |
YMR046C |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PUS6 |
YGR169C |
tRNA:pseudouridine synthase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
physical |
1 |
1 |
1 |
Two-hybrid |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
physical |
1 |
1 |
1 |
Two-hybrid |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
physical |
1 |
1 |
1 |
Two-hybrid |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Co-purification |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| RNQ1 |
YCL028W |
[PIN(+)] prion |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
physical |
1 |
1 |
1 |
Two-hybrid |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TFA1 |
YKL028W |
TFIIE large subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIF2 |
YLR453C |
Protein that binds to the Rap1p C-terminus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNR3 |
YIL066C |
Minor isoform of large subunit of ribonucleotide-diphosphate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT106 |
YNL206C |
Histone chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDH54 |
YBR073W |
DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB4 |
YJL140W |
RNA polymerase II subunit B32 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| THO2 |
YNL139C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RIM11 |
YMR139W |
Protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| SMK1 |
YPR054W |
Middle sporulation-specific mitogen-activated protein kinase (MAPK) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
1 |
1 |
1 |
Two-hybrid |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GYP5 |
YPL249C |
GTPase-activating protein (GAP) for yeast Rab family members |
physical |
1 |
1 |
1 |
Two-hybrid |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
| ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
physical |
1 |
1 |
1 |
Two-hybrid |
| MSH5 |
YDL154W |
Protein of the MutS family |
physical |
1 |
1 |
1 |
Two-hybrid |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHP6A |
YPR052C |
High-mobility group (HMG) protein |
physical |
1 |
1 |
1 |
PCA |
| NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| NOT5 |
YPR072W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Two-hybrid |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IOC4 |
YMR044W |
Member of a complex (Isw1b) with Isw1p and Ioc2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNR1 |
YIL159W |
Formin |
physical |
1 |
1 |
1 |
Two-hybrid |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP32 |
YFL046W |
Regulator of mitochondrial proline metabolism |
physical |
1 |
1 |
1 |
Two-hybrid |
| HSK3 |
YKL138C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
| NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| IRC3 |
YDR332W |
Double-stranded DNA-dependent helicase of the DExH/D-box family |
physical |
1 |
1 |
1 |
Two-hybrid |
| ERP3 |
YDL018C |
Protein with similarity to Emp24p and Erv25p |
physical |
1 |
1 |
1 |
Two-hybrid |
| HST4 |
YDR191W |
NAD(+)-dependent protein deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPR1 |
YNL183C |
Protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| AIM34 |
YMR003W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LAM4 |
YHR080C |
Sterol-binding protein that localizes to puncta in the cortical ER |
physical |
1 |
1 |
1 |
Two-hybrid |
| ARR1 |
YPR199C |
Transcriptional activator of the basic leucine zipper (bZIP) family |
physical |
1 |
1 |
1 |
Two-hybrid |
