| ATG3 |
YNR007C |
E2-like enzyme |
physical |
19 |
5 |
17 |
Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS |
| ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
physical |
19 |
5 |
13 |
Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, Co-crystal Structure, Affinity Capture-MS |
| ATG19 |
YOL082W |
Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway |
physical |
15 |
6 |
11 |
Affinity Capture-Western, Protein-peptide, Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western |
| ATG4 |
YNL223W |
Conserved cysteine protease required for autophagy |
physical |
12 |
4 |
8 |
Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Two-hybrid, Biochemical Activity, Biochemical Activity, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex |
| ATG32 |
YIL146C |
Mitochondrial outer membrane protein required to initiate mitophagy |
physical |
10 |
3 |
7 |
Two-hybrid, Affinity Capture-Western, Two-hybrid, Co-crystal Structure, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
7 |
6 |
6 |
Biochemical Activity, Two-hybrid, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Co-localization, Affinity Capture-MS |
| ATG40 |
YOR152C |
Autophagy receptor with a role in endoplasmic reticulum degradation |
physical |
7 |
5 |
4 |
Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Co-crystal Structure, Affinity Capture-Western, Protein-peptide, Co-crystal Structure |
| NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
7 |
4 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, PCA |
| CUE5 |
YOR042W |
Ubiquitin-binding protein |
physical |
6 |
3 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
physical |
5 |
5 |
1 |
Co-crystal Structure, Affinity Capture-MS, Affinity Capture-Western, Co-localization, Reconstituted Complex |
| APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
physical |
4 |
4 |
4 |
Affinity Capture-Western, Co-localization, Affinity Capture-MS, Reconstituted Complex |
| ATG4 |
YNL223W |
Conserved cysteine protease required for autophagy |
genetic |
4 |
3 |
4 |
Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
| ATG34 |
YOL083W |
Receptor protein involved in selective autophagy during starvation |
physical |
4 |
3 |
4 |
Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
physical |
4 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, PCA |
| FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
physical |
4 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
4 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| POM152 |
YMR129W |
Glycoprotein subunit of transmembrane ring of nuclear pore complex |
physical |
4 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
4 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
physical |
4 |
3 |
1 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-localization |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, quantitative reverse transcription polymerase chain reaction evidence, quantitative reverse transcription polymerase chain reaction evidence |
| ATG39 |
YLR312C |
Transmembrane receptor with a role in nucleophagy |
physical |
3 |
3 |
2 |
Affinity Capture-Western, Two-hybrid, Affinity Capture-MS |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| NDC1 |
YML031W |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| NUP82 |
YJL061W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| NUP49 |
YGL172W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARF2 |
YDL137W |
ADP-ribosylation factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PIL1 |
YGR086C |
Eisosome core component |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BMT2 |
YBR141C |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VBA2 |
YBR293W |
Permease of basic amino acids in the vacuolar membrane |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SAS4 |
YDR181C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PEX3 |
YDR329C |
Peroxisomal membrane protein (PMP) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HXT1 |
YHR094C |
Low-affinity glucose transporter of the major facilitator superfamily |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SOP4 |
YJL192C |
ER-membrane protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
physical |
3 |
3 |
1 |
PCA, Affinity Capture-Western, Reconstituted Complex |
| ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression |
| ATG36 |
YJL185C |
Pex3p interacting protein, required for pexophagy |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Two-hybrid |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
| SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
2 |
2 |
2 |
Co-localization, Affinity Capture-MS |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
2 |
2 |
2 |
Co-fractionation, Affinity Capture-Western |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Co-localization |
| EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NUP157 |
YER105C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NIC96 |
YFR002W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YMC2 |
YBR104W |
Putative mitochondrial inner membrane transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL41A |
YDL184C |
Ribosomal 60S subunit protein L41A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BOR1 |
YNL275W |
Boron efflux transporter of the plasma membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PKH1 |
YDR490C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Dosage Rescue |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
| HFL1 |
YKR051W |
Vacuole membrane protein that interacts with Atg8p |
physical |
2 |
2 |
1 |
Co-localization, Reconstituted Complex |
| NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
| IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Enhancement |
| ATG21 |
YPL100W |
Phosphoinositide binding protein |
physical |
2 |
2 |
1 |
PCA, Reconstituted Complex |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NYV1 |
YLR093C |
v-SNARE component of the vacuolar SNARE complex |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PAU4 |
YLR461W |
Member of the seripauperin multigene family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| CYS3 |
YAL012W |
Cystathionine gamma-lyase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
| CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
| SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
| SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AMS1 |
YGL156W |
Vacuolar alpha mannosidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APE2 |
YKL157W |
Aminopeptidase yscII |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG13 |
YPR185W |
Regulatory subunit of the Atg1p signaling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ATP14 |
YLR295C |
Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRC1 |
YOR100C |
Mitochondrial inner membrane carnitine transporter |
physical |
1 |
1 |
1 |
PCA |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HMG2 |
YLR450W |
HMG-CoA reductase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MPS1 |
YDL028C |
Dual-specificity kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Co-localization |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
Co-localization |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DNF2 |
YDR093W |
Aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VTH1 |
YIL173W |
Putative membrane glycoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC22 |
YLR268W |
R-SNARE protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOP1 |
YPR028W |
Reticulon-interacting protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DNF1 |
YER166W |
Aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FTH1 |
YBR207W |
Putative high affinity iron transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMP24 |
YGL200C |
Component of the p24 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC21 |
YNL287W |
Gamma subunit of coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFT1 |
YKL006C-A |
Intra-Golgi v-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSP120 |
YLR250W |
Protein packaged into COPII vesicles for ER to Golgi trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TVP38 |
YKR088C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPT31 |
YER031C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PEP12 |
YOR036W |
Target membrane receptor (t-SNARE) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIP3 |
YNL044W |
Protein localized to COPII vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMP47 |
YFL048C |
Integral membrane component of ER-derived COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT1 |
YFL038C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSO1 |
YPL232W |
Plasma membrane t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFT2 |
YBL102W |
Tetra-spanning membrane protein found mostly in the late Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP42 |
YDR192C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP2 |
YLR335W |
Nucleoporin involved in nucleocytoplasmic transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Co-localization |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CLC1 |
YGR167W |
Clathrin light chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YAP1802 |
YGR241C |
Protein of the AP180 family, involved in clathrin cage assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YAP1801 |
YHR161C |
Protein of the AP180 family, involved in clathrin cage assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ENT1 |
YDL161W |
Epsin-like protein involved in endocytosis and actin patch assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SYP1 |
YCR030C |
Negative regulator of WASP-Arp23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PAL1 |
YDR348C |
Protein of unknown function thought to be involved in endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TRM8 |
YDL201W |
Catalytic subunit of a tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM27 |
YJR106W |
Protein involved in calcium homeostasis and exit from quiescence |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC3 |
YER008C |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL2B |
YIL018W |
Ribosomal 60S subunit protein L2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PNG1 |
YPL096W |
Conserved peptide N-glycanase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POP5 |
YAL033W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUT1 |
YBR252W |
Deoxyuridine triphosphate diphosphatase (dUTPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URB2 |
YJR041C |
Protein required for normal metabolism of the rRNA primary transcript |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUS1 |
YMR240C |
Protein required for assembly of U2 snRNP into the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI12 |
YMR281W |
ER membrane protein involved in the second step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYN8 |
YAL014C |
Endosomal SNARE related to mammalian syntaxin 8 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUE3 |
YGL110C |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRR2 |
YHR106W |
Mitochondrial thioredoxin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIP2 |
YPL155C |
Kinesin-related motor protein involved in mitotic spindle positioning |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERS1 |
YCR075C |
Protein involved in cystine transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX29 |
YDR479C |
ER-resident protein involved in peroxisomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMT1 |
YER175C |
Trans-aconitate methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLO1 |
YER180C-A |
Protein interacting with Arl3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI5 |
YFL058W |
Protein involved in synthesis of the thiamine precursor HMP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP48 |
YGR052W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM13 |
YGR181W |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRX2 |
YGR209C |
Cytoplasmic thioredoxin isoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPS6 |
YIR039C |
Putative GPI-anchored aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX2 |
YJL210W |
RING-finger peroxin and E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR151W-A |
YJR151W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL054C |
YLL054C |
Putative protein of unknown function with similarity to Pip2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR179C |
YLR179C |
Protein of unknown function with similarity to Tfs1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR419W |
YLR419W |
Putative helicase with limited sequence similarity to human Rb protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUE4 |
YML101C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CIN4 |
YMR138W |
GTP-binding protein involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATR2 |
YMR279C |
Putative boron transporter involved in boron efflux and resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX17 |
YNL214W |
Membrane peroxin of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YSP3 |
YOR003W |
Putative precursor of the subtilisin-like protease III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCN2 |
YOR220W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASF2 |
YDL197C |
Anti-silencing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APE4 |
YHR113W |
Cytoplasmic aspartyl aminopeptidase with possible vacuole function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| APT2 |
YDR441C |
Potential adenine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADY2 |
YCR010C |
Acetate transporter required for normal sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALP1 |
YNL270C |
Arginine transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
