Standard name Systematic name Name description Description
END3 YNL084C EH domain-containing protein involved in endocytosis EH domain-containing protein involved in endocytosis; actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p
Visualize the interactome of END3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.233 0.185 0.237
Budsite 0.120 NaN NaN
Cell Periphery 0.116 0.185 0.086
Cort. Patches 0.764 0.802 0.785
Cytoplasm 0.055 0.062 0.075
Golgi 0.055 0.056 0.183
Mito 0.422 0.191 0.140
Peroxisome 0.142 0.056 0.204
ER NaN 0.117 NaN

GFP localization & abundance

GFP localization GFP abundance
punctate composite 2610

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
END3 0 1 1 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 16 5 9 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Co-fractionation, Affinity Capture-Western
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 9 4 6 Dosage Rescue, Dosage Rescue, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression, Synthetic Lethality, Phenotypic Enhancement, Synthetic Lethality, Phenotypic Suppression
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 5 3 4 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 4 3 2 Synthetic Lethality, Synthetic Lethality, Phenotypic Suppression, Phenotypic Enhancement
LAS17 YOR181W Actin assembly factor physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, PCA
YAP1802 YGR241C Protein of the AP180 family, involved in clathrin cage assembly physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
SLA1 YBL007C Cytoskeletal protein binding protein physical 3 3 2 Affinity Capture-Western, Two-hybrid, PCA
SCD5 YOR329C Protein required for normal actin organization and endocytosis physical 3 2 2 Two-hybrid, Affinity Capture-Western, Two-hybrid
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 3 2 2 Dosage Rescue, Synthetic Growth Defect, Dosage Rescue
KEL1 YHR158C Protein required for proper cell fusion and cell morphology physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
PRK1 YIL095W Ser/Thr protein kinase genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 3 2 1 PCA, Two-hybrid, Two-hybrid
SLA1 YBL007C Cytoskeletal protein binding protein genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 2 2 2 Two-hybrid, Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair physical 2 1 2 Two-hybrid, Two-hybrid
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) physical 2 1 2 Two-hybrid, Two-hybrid
MET4 YNL103W Leucine-zipper transcriptional activator physical 2 1 2 Two-hybrid, Two-hybrid
SCD5 YOR329C Protein required for normal actin organization and endocytosis genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ELM1 YKL048C Serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex physical 2 2 1 PCA, Two-hybrid
NIP100 YPL174C Large subunit of the dynactin complex physical 2 2 1 PCA, Two-hybrid
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 2 2 1 PCA, Two-hybrid
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 2 2 1 PCA, Two-hybrid
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 2 2 1 PCA, Two-hybrid
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p physical 2 1 1 Two-hybrid, Two-hybrid
ERP5 YHR110W Protein with similarity to Emp24p and Erv25p physical 2 1 1 Two-hybrid, Two-hybrid
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 2 1 1 Two-hybrid, Two-hybrid
HMS2 YJR147W Protein with similarity to heat shock transcription factors physical 2 1 1 Two-hybrid, Two-hybrid
STB2 YMR053C Protein that interacts with Sin3p in a two-hybrid assay physical 2 1 1 Two-hybrid, Two-hybrid
SHE9 YDR393W Protein required for normal mitochondrial morphology physical 2 1 1 Two-hybrid, Two-hybrid
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function physical 2 1 1 Two-hybrid, Two-hybrid
YPL216W YPL216W Putative protein of unknown function physical 2 1 1 Two-hybrid, Two-hybrid
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
BNR1 YIL159W Formin physical 2 1 1 Two-hybrid, Two-hybrid
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum physical 2 1 1 Two-hybrid, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 1 1 1 Two-hybrid
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 1 1 1 Two-hybrid
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Lethality
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Synthetic Lethality
BDF1 YLR399C BET family transcriptional regulator physical 1 1 1 Two-hybrid
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CHC1 YGL206C Clathrin heavy chain genetic 1 1 1 Phenotypic Enhancement
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Synthetic Growth Defect
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites physical 1 1 1 Two-hybrid
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex genetic 1 1 1 Positive Genetic
ECM29 YHL030W Scaffold protein physical 1 1 1 Affinity Capture-MS
KAR5 YMR065W Protein required for nuclear membrane fusion during karyogamy physical 1 1 1 Two-hybrid
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p physical 1 1 1 Two-hybrid
XRS2 YDR369C FHA domain-containing component of the Mre11 complex physical 1 1 1 Affinity Capture-MS
YRB2 YIL063C Protein of unknown function physical 1 1 1 Affinity Capture-MS
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein physical 1 1 1 Affinity Capture-MS
RPC53 YDL150W RNA polymerase III subunit C53 physical 1 1 1 Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Two-hybrid
VRP1 YLR337C Verprolin, proline-rich actin-associated protein physical 1 1 1 PCA
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis physical 1 1 1 PCA
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Synthetic Lethality
YSC84 YHR016C Actin-binding protein physical 1 1 1 Two-hybrid
MYO3 YKL129C One of two type I myosins physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Two-hybrid
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Two-hybrid
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
ERP3 YDL018C Protein with similarity to Emp24p and Erv25p physical 1 1 1 Two-hybrid
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Two-hybrid
SAC3 YDR159W mRNA export factor physical 1 1 1 Two-hybrid
PAM1 YDR251W Essential protein of unknown function physical 1 1 1 Two-hybrid
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 1 1 1 Two-hybrid
VPS60 YDR486C Protein involved in late endosome to vacuole transport physical 1 1 1 Two-hybrid
GTA1 YEL043W Protein of unknown function physical 1 1 1 Two-hybrid
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 1 1 1 Two-hybrid
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Two-hybrid
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 1 1 1 Two-hybrid
KXD1 YGL079W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Two-hybrid
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Two-hybrid
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER physical 1 1 1 Two-hybrid
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Two-hybrid
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Two-hybrid
STB6 YKL072W Protein that binds Sin3p in a two-hybrid assay physical 1 1 1 Two-hybrid
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Negative Genetic
SNF7 YLR025W One of four subunits of the ESCRT-III complex physical 1 1 1 Two-hybrid
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex physical 1 1 1 Two-hybrid
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 1 1 1 Two-hybrid
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex physical 1 1 1 Two-hybrid
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE physical 1 1 1 Two-hybrid
IMH1 YLR309C Protein involved in vesicular transport physical 1 1 1 Two-hybrid
PDS5 YMR076C Cohesion maintenance factor physical 1 1 1 Two-hybrid
TAF7 YMR227C TFIID subunit (67 kDa) physical 1 1 1 Two-hybrid
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Two-hybrid
FRT2 YAL028W Tail-anchored ER membrane protein of unknown function physical 1 1 1 Two-hybrid
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Two-hybrid
GTB1 YDR221W Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p physical 1 1 1 Two-hybrid
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
SMC1 YFL008W Subunit of the multiprotein cohesin complex physical 1 1 1 Two-hybrid
ERP6 YGL002W Member of the p24 family involved in ER to Golgi transport physical 1 1 1 Two-hybrid
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex physical 1 1 1 Two-hybrid
SKA1 YKL023W SKI complex-associated protein physical 1 1 1 Two-hybrid
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 Two-hybrid
END3 YNL084C EH domain-containing protein involved in endocytosis physical 1 1 1 Two-hybrid
SMC5 YOL034W Subunit of the SMC5-SMC6 complex physical 1 1 1 Two-hybrid
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Two-hybrid
KAR3 YPR141C Minus-end-directed microtubule motor physical 1 1 1 Two-hybrid
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 1 1 1 Two-hybrid
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 1 1 1 Two-hybrid
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family physical 1 1 1 Two-hybrid
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Two-hybrid
MGE1 YOR232W Mitochondrial matrix cochaperone physical 1 1 1 Two-hybrid
PAC1 YOR269W Regulator of dynein, involved in intracellular transport physical 1 1 1 Two-hybrid
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
SPP1 YPL138C Subunit of COMPASS (Set1C) physical 1 1 1 Two-hybrid
NOP53 YPL146C Nucleolar protein physical 1 1 1 Two-hybrid
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members physical 1 1 1 Two-hybrid
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex physical 1 1 1 Two-hybrid
HOB2 YPR117W Protein with structural similarity to lipid transport protein Vps13p physical 1 1 1 Two-hybrid
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
TAT1 YBR069C Amino acid transporter for valine, leucine, isoleucine, and tyrosine physical 1 1 1 Co-localization
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Synthetic Lethality
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Dosage Rescue
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Synthetic Growth Defect
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Synthetic Rescue
YPP1 YGR198W Cargo-transport protein involved in endocytosis genetic 1 1 1 Phenotypic Enhancement
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Growth Defect
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Phenotypic Suppression
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Phenotypic Enhancement
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Phenotypic Enhancement
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Enhancement
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Synthetic Lethality
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Synthetic Growth Defect
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Growth Defect
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Lethality
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Lethality
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Positive Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Positive Genetic
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex genetic 1 1 1 Positive Genetic
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 genetic 1 1 1 Positive Genetic
YLL054C YLL054C Putative protein of unknown function with similarity to Pip2p genetic 1 1 1 Positive Genetic
HXT10 YFL011W Hexose transporter genetic 1 1 1 Positive Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
KIN2 YLR096W S/T protein kinase genetic 1 1 1 Negative Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
KIN1 YDR122W S/T protein kinase genetic 1 1 1 Negative Genetic
TSC10 YBR265W 3-ketosphinganine reductase genetic 1 1 1 Negative Genetic
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 1 1 1 Negative Genetic
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Phenotypic Enhancement
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Phenotypic Suppression
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Phenotypic Suppression
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Positive Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone genetic 1 1 1 Positive Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Positive Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 1 1 1 Positive Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Positive Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Positive Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Positive Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Phenotypic Suppression
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Phenotypic Suppression
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Phenotypic Enhancement
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 1 1 1 Negative Genetic
RCR1 YBR005W Plasma membrane (PM) ubiquitin ligase-substrate adaptor genetic 1 1 1 Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck genetic 1 1 1 Negative Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Negative Genetic
KAR4 YCL055W Transcription factor required for response to pheromones genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
YDL012C YDL012C Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
RTN2 YDL204W Reticulon protein genetic 1 1 1 Negative Genetic
YDL211C YDL211C Protein of unknown function genetic 1 1 1 Negative Genetic
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
YOS9 YDR057W ER quality-control lectin genetic 1 1 1 Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
IPT1 YDR072C Inositolphosphotransferase genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
TVP15 YDR100W Integral membrane protein genetic 1 1 1 Negative Genetic
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YDR131C YDR131C F-box protein subunit of SCF ubiquitin ligase complex genetic 1 1 1 Negative Genetic
MRX16 YDR132C Protein that associates with the large mitoribosomal subunit genetic 1 1 1 Negative Genetic
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter genetic 1 1 1 Negative Genetic
ENT5 YDR153C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
RKM2 YDR198C Ribosomal protein lysine methyltransferase genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p genetic 1 1 1 Negative Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 1 1 1 Negative Genetic
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex genetic 1 1 1 Negative Genetic
MRX8 YDR336W Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
SVF1 YDR346C Protein with a potential role in cell survival pathways genetic 1 1 1 Negative Genetic
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis genetic 1 1 1 Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
PHO8 YDR481C Repressible vacuolar alkaline phosphatase genetic 1 1 1 Negative Genetic
PSP1 YDR505C Asn and gln rich protein of unknown function genetic 1 1 1 Negative Genetic
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
YGL242C YGL242C Protein of unknown function genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
PIL1 YGR086C Eisosome core component genetic 1 1 1 Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Negative Genetic
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
SCW4 YGR279C Cell wall protein with similarity to glucanases genetic 1 1 1 Negative Genetic
OTU2 YHL013C Protein of unknown function genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
EST3 YIL009C-A Component of the telomerase holoenzyme genetic 1 1 1 Negative Genetic
TED1 YIL039W GPI-glycan remodelase genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
YKL162C YKL162C Putative protein of unknown function genetic 1 1 1 Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
YLR287C YLR287C Putative protein of unknown function genetic 1 1 1 Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Negative Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
RCH1 YMR034C Negative regulator of cytosolic calcium homeostasis genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Negative Genetic
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
LAG2 YOL025W Protein that negatively regulates the SCF E3-ubiquitin ligase genetic 1 1 1 Negative Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Negative Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 1 1 1 Negative Genetic
YPQ1 YOL092W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
YSP3 YOR003W Putative precursor of the subtilisin-like protease III genetic 1 1 1 Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Negative Genetic
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 1 1 1 Negative Genetic
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
YOR131C YOR131C Putative haloacid dehalogenase-like hydrolase genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Negative Genetic
MET12 YPL023C Protein with MTHFR activity in vitro genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
SDD4 YPR022C Putative transcription factor, as suggested by computational analysis genetic 1 1 1 Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
SYP1 YCR030C Negative regulator of WASP-Arp23 complex genetic 1 1 1 Phenotypic Suppression
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Synthetic Lethality
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Synthetic Rescue
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Negative Genetic
BBC1 YJL020C Protein possibly involved in assembly of actin patches genetic 1 1 1 Negative Genetic
CNB1 YKL190W Calcineurin B genetic 1 1 1 Negative Genetic
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 1 1 1 Synthetic Lethality
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 1 1 1 Negative Genetic
AIR1 YIL079C Zinc knuckle protein genetic 1 1 1 Synthetic Lethality
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Two-hybrid
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Positive Genetic
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Synthetic Growth Defect
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Two-hybrid
CNM67 YNL225C Component of the spindle pole body outer plaque physical 1 1 1 Two-hybrid
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Phenotypic Suppression
ARK1 YNL020C Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Phenotypic Enhancement
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Negative Genetic
ATX1 YNL259C Cytosolic copper metallochaperone genetic 1 1 1 Synthetic Lethality
BTT1 YDR252W Heterotrimeric nascent polypeptide-associated complex beta3 subunit genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Synthetic Growth Defect
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
COM2 YER130C Transcription factor that binds IME1 Upstream Activation Signal (UAS) genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
DPL1 YDR294C Dihydrosphingosine phosphate lyase genetic 1 1 1 Negative Genetic
CNE1 YAL058W Calnexin genetic 1 1 1 Negative Genetic