Standard name Systematic name Name description Description
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit cAMP-dependent protein kinase catalytic subunit; role in nutrient-stimulated growth via Ras-cAMP signaling; inhibited by regulatory subunit Bcy1p in cAMPs absence; phosphorylates and inhibits Whi3p to promote G1/S phase passage; phosphorylates Nej1p to regulate nonhomologous end joining (NHEJ); impairs mitochondrial import of pre-Tom40p via phosphorylation under non-respiratory conditions; partially redundant with Tpk2p and Tpk3p; human homolog PRKACB regulates NHEJ via NHEJ1 phosphorylation
Visualize the interactome of TPK1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.773 0.565 0.232
Mito 0.127 NaN NaN
Vac/Vac Memb 0.180 0.402 0.486
Nucleus NaN 0.065 0.387

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 4320

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TPK1 9 0 0 7 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) physical 14 6 13 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Biochemical Activity, Two-hybrid, Two-hybrid, PCA, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
RAS2 YNL098C GTP-binding protein genetic 9 3 8 Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Phenotypic Suppression, Dosage Rescue, Dosage Rescue, Dosage Rescue, Phenotypic Suppression
YAK1 YJL141C Serine-threonine protein kinase physical 8 4 4 Biochemical Activity, Two-hybrid, Two-hybrid, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 7 4 7 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Lethality, Phenotypic Enhancement
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 7 3 7 Synthetic Lethality, Negative Genetic, Negative Genetic, Phenotypic Suppression, Synthetic Lethality, Negative Genetic, Negative Genetic
NTH1 YDR001C Neutral trehalase, degrades trehalose physical 7 2 6 Biochemical Activity, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor physical 7 3 3 Affinity Capture-Western, Biochemical Activity, Two-hybrid, Two-hybrid, Affinity Capture-Western, Biochemical Activity, Biochemical Activity
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 5 2 5 Synthetic Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Synthetic Rescue
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Affinity Capture-MS
CDC19 YAL038W Pyruvate kinase physical 5 2 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Biochemical Activity
BMH1 YER177W 14-3-3 protein, major isoform genetic 4 4 4 Dosage Rescue, Synthetic Growth Defect, Synthetic Rescue, Phenotypic Enhancement
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 4 2 4 PCA, PCA, PCA, Biochemical Activity
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Affinity Capture-MS
TRM2 YKR056W tRNA methyltransferase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EDS1 YBR033W Putative zinc cluster protein, predicted to be a transcription factor genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PKH1 YDR490C Serine/threonine protein kinase physical 4 3 2 Reconstituted Complex, Biochemical Activity, Biochemical Activity, Affinity Capture-Western
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YDL186W YDL186W Putative protein of unknown function genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CKI1 YLR133W Choline kinase physical 3 3 2 Biochemical Activity, Affinity Capture-Western, Two-hybrid
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes physical 3 2 2 Affinity Capture-Western, Biochemical Activity, Biochemical Activity
PYK2 YOR347C Pyruvate kinase physical 3 2 2 Biochemical Activity, Reconstituted Complex, Biochemical Activity
HSL1 YKL101W Nim1p-related protein kinase genetic 2 2 2 Positive Genetic, Negative Genetic
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 2 2 2 Biochemical Activity, PCA
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Rescue, Negative Genetic
YMR196W YMR196W Putative protein of unknown function physical 2 2 2 Biochemical Activity, Affinity Capture-MS
YAK1 YJL141C Serine-threonine protein kinase genetic 2 2 2 Dosage Rescue, Synthetic Rescue
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients physical 2 2 2 Affinity Capture-MS, Two-hybrid
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 2 2 2 Biochemical Activity, Reconstituted Complex
MSN4 YKL062W Stress-responsive transcriptional activator genetic 2 2 2 Synthetic Growth Defect, Phenotypic Enhancement
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 2 1 2 Negative Genetic, Negative Genetic
CYR1 YJL005W Adenylate cyclase genetic 2 1 2 Dosage Rescue, Dosage Rescue
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 2 1 2 Dosage Rescue, Dosage Rescue
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 2 1 2 Negative Genetic, Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 2 1 2 Positive Genetic, Positive Genetic
SWI6 YLR182W Transcription cofactor genetic 2 1 2 Negative Genetic, Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 2 1 2 Negative Genetic, Negative Genetic
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 2 1 2 Biochemical Activity, Biochemical Activity
SSO1 YPL232W Plasma membrane t-SNARE physical 2 1 2 Biochemical Activity, Biochemical Activity
SCH9 YHR205W AGC family protein kinase genetic 2 1 2 Dosage Rescue, Dosage Rescue
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex physical 2 1 2 Biochemical Activity, Biochemical Activity
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis physical 2 2 1 Two-hybrid, Biochemical Activity
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor regulation 1 1 1 protein kinase assay evidence
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) regulation 1 1 1 protein kinase assay evidence
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) regulation 1 1 1 protein kinase assay evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing physical 1 1 1 Biochemical Activity
LEO1 YOR123C Component of the Paf1 complex physical 1 1 1 Biochemical Activity
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 1 1 1 Affinity Capture-MS
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit physical 1 1 1 Affinity Capture-MS
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p physical 1 1 1 Biochemical Activity
HSP60 YLR259C Tetradecameric mitochondrial chaperonin physical 1 1 1 Biochemical Activity
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Biochemical Activity
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Biochemical Activity
ECM2 YBR065C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p physical 1 1 1 Biochemical Activity
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic physical 1 1 1 Biochemical Activity
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Biochemical Activity
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Biochemical Activity
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Biochemical Activity
HCA4 YJL033W DEAD box RNA helicase physical 1 1 1 Biochemical Activity
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Biochemical Activity
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Negative Genetic
RPB4 YJL140W RNA polymerase II subunit B32 physical 1 1 1 Affinity Capture-MS
RPB7 YDR404C RNA polymerase II subunit B16 physical 1 1 1 Affinity Capture-MS
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Reconstituted Complex
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS physical 1 1 1 Biochemical Activity
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Biochemical Activity
REI1 YBR267W Cytoplasmic pre-60S factor genetic 1 1 1 Negative Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Biochemical Activity
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Biochemical Activity
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) physical 1 1 1 Biochemical Activity
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Phenotypic Suppression
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Biochemical Activity
SSD1 YDR293C Translational repressor physical 1 1 1 Biochemical Activity
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 1 1 1 Biochemical Activity
SUP35 YDR172W Translation termination factor eRF3 physical 1 1 1 Biochemical Activity
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III physical 1 1 1 Biochemical Activity
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Dosage Rescue
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Two-hybrid
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) physical 1 1 1 Biochemical Activity
CNS1 YBR155W TPR-containing co-chaperone physical 1 1 1 Biochemical Activity
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Biochemical Activity
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Biochemical Activity
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 1 1 1 Biochemical Activity
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Positive Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Dosage Rescue
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Dosage Lethality
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Biochemical Activity
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Synthetic Lethality
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Biochemical Activity
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Dosage Growth Defect
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 1 1 1 Biochemical Activity
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Growth Defect
RPB11 YOL005C RNA polymerase II subunit B12.5 physical 1 1 1 Affinity Capture-MS
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 1 1 1 Affinity Capture-MS
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex physical 1 1 1 Biochemical Activity
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Biochemical Activity
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III physical 1 1 1 Biochemical Activity
SEC13 YLR208W Structural component of 3 complexes genetic 1 1 1 Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex physical 1 1 1 Biochemical Activity
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
AVT4 YNL101W Vacuolar transporter physical 1 1 1 Biochemical Activity
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton physical 1 1 1 Biochemical Activity
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 physical 1 1 1 Affinity Capture-MS
SMX2 YFL017W-A Core Sm protein Sm G physical 1 1 1 Biochemical Activity
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex physical 1 1 1 Biochemical Activity
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Biochemical Activity
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Biochemical Activity
SUI3 YPL237W Beta subunit of the translation initiation factor eIF2 physical 1 1 1 Reconstituted Complex
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Synthetic Rescue
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Biochemical Activity
TIF5 YPR041W Translation initiation factor eIF5 genetic 1 1 1 Phenotypic Suppression
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Dosage Rescue
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 1 1 1 Biochemical Activity
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi physical 1 1 1 Biochemical Activity
TLG2 YOL018C Syntaxin-like t-SNARE physical 1 1 1 Biochemical Activity
CMS1 YLR003C Putative subunit of the 90S preribosome processome complex physical 1 1 1 Biochemical Activity
LAP2 YNL045W Leucyl aminopeptidase yscIV with epoxide hydrolase activity physical 1 1 1 Biochemical Activity
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 1 1 1 Biochemical Activity
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping physical 1 1 1 Biochemical Activity
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen physical 1 1 1 Biochemical Activity
MSD1 YPL104W Mitochondrial aspartyl-tRNA synthetase physical 1 1 1 Biochemical Activity
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Biochemical Activity
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane physical 1 1 1 Affinity Capture-MS
IRA2 YOL081W GTPase-activating protein physical 1 1 1 Biochemical Activity
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Synthetic Rescue
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Biochemical Activity
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
YPT53 YNL093W Stress-induced Rab family GTPase physical 1 1 1 Affinity Capture-MS
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Biochemical Activity
YPL077C YPL077C Putative protein of unknown function physical 1 1 1 Biochemical Activity
YJL218W YJL218W Mitochondrial protein, putative acetyltransferase physical 1 1 1 Biochemical Activity
YGR038C-A YGR038C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YDR239C YDR239C Protein of unknown function physical 1 1 1 Biochemical Activity
YHR214C-C YHR214C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Biochemical Activity
YPK3 YBR028C AGC kinase physical 1 1 1 Biochemical Activity
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Biochemical Activity
YBL055C YBL055C 3'-->5' exonuclease and endonuclease with a possible role in apoptosis physical 1 1 1 Biochemical Activity
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor physical 1 1 1 Biochemical Activity
YLR410W-A YLR410W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
UTP7 YER082C Nucleolar protein physical 1 1 1 Biochemical Activity
UBP6 YFR010W Ubiquitin-specific protease physical 1 1 1 Biochemical Activity
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p physical 1 1 1 Biochemical Activity
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p physical 1 1 1 Biochemical Activity
YCR016W YCR016W Putative protein of unknown function physical 1 1 1 Biochemical Activity
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
WHI5 YOR083W Repressor of G1 transcription physical 1 1 1 Biochemical Activity
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
TRM1 YDR120C tRNA methyltransferase physical 1 1 1 Biochemical Activity
YML037C YML037C Putative protein of unknown function physical 1 1 1 Biochemical Activity
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Biochemical Activity
YML045W-A YML045W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Biochemical Activity
YPL257W-A YPL257W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YLR345W YLR345W Similar to 6-phosphofructo-2-kinase enzymes physical 1 1 1 Biochemical Activity
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Biochemical Activity
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Biochemical Activity
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) physical 1 1 1 Biochemical Activity
YPT35 YHR105W Endosomal protein of unknown function physical 1 1 1 Biochemical Activity
UTR1 YJR049C ATP-NADH kinase physical 1 1 1 Biochemical Activity
YER010C YER010C Bifunctional HMG aldolase/oxaloacetate decarboxylase physical 1 1 1 Biochemical Activity
ZRG17 YNR039C Endoplasmic reticulum zinc transporter physical 1 1 1 Biochemical Activity
YGR266W YGR266W Protein of unknown function physical 1 1 1 Biochemical Activity
UME6 YDR207C Rpd3L histone deacetylase complex subunit physical 1 1 1 Biochemical Activity
VHS2 YIL135C Regulator of septin dynamics physical 1 1 1 Biochemical Activity
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein physical 1 1 1 Biochemical Activity
TPO1 YLL028W Polyamine transporter of the major facilitator superfamily physical 1 1 1 Biochemical Activity
YGR210C YGR210C Putative protein of unknown function physical 1 1 1 Biochemical Activity
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase physical 1 1 1 Reconstituted Complex
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Biochemical Activity
TSA1 YML028W Thioredoxin peroxidase physical 1 1 1 Affinity Capture-Western
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Phenotypic Suppression
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Dosage Growth Defect
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Positive Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Synthetic Rescue
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
FOL2 YGR267C GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis physical 1 1 1 Biochemical Activity
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 Biochemical Activity
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Biochemical Activity
KIN1 YDR122W S/T protein kinase physical 1 1 1 PCA
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 1 1 1 Biochemical Activity
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Negative Genetic
LCP5 YER127W Essential protein involved in maturation of 18S rRNA physical 1 1 1 Biochemical Activity
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Phenotypic Enhancement
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Positive Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 physical 1 1 1 Reconstituted Complex
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network genetic 1 1 1 Dosage Rescue
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) physical 1 1 1 Affinity Capture-Western
LAF1 YMR102C Sterol-binding beta-propeller protein physical 1 1 1 Biochemical Activity
GIP2 YER054C Putative regulatory subunit of protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
PDS1 YDR113C Securin physical 1 1 1 Biochemical Activity
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis physical 1 1 1 Biochemical Activity
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
ARE2 YNR019W Acyl-CoA:sterol acyltransferase physical 1 1 1 Biochemical Activity
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p physical 1 1 1 Biochemical Activity
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Biochemical Activity
ERG20 YJL167W Farnesyl pyrophosphate synthetase physical 1 1 1 Biochemical Activity
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
ADD66 YKL206C Protein involved in 20S proteasome assembly physical 1 1 1 Biochemical Activity
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 1 1 1 Biochemical Activity
RAS2 YNL098C GTP-binding protein physical 1 1 1 Biochemical Activity
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Biochemical Activity
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 1 1 1 Phenotypic Suppression
PGM1 YKL127W Phosphoglucomutase, minor isoform physical 1 1 1 Biochemical Activity
ICP55 YER078C Mitochondrial aminopeptidase physical 1 1 1 Biochemical Activity
NOP53 YPL146C Nucleolar protein physical 1 1 1 Biochemical Activity
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 1 1 1 Biochemical Activity
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth physical 1 1 1 Biochemical Activity
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Biochemical Activity
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase physical 1 1 1 Biochemical Activity
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
IGO1 YNL157W Protein required for initiation of G0 program physical 1 1 1 Biochemical Activity
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p physical 1 1 1 Biochemical Activity
APL4 YPR029C Gamma-adaptin physical 1 1 1 Biochemical Activity
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
FZF1 YGL254W Transcription factor involved in sulfite metabolism physical 1 1 1 Biochemical Activity
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Biochemical Activity
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Biochemical Activity
LAC1 YKL008C Ceramide synthase component physical 1 1 1 Biochemical Activity
ALR1 YOL130W Plasma membrane Mg(2+) transporter physical 1 1 1 Biochemical Activity
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Biochemical Activity
GZF3 YJL110C GATA zinc finger protein genetic 1 1 1 Negative Genetic
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p physical 1 1 1 Biochemical Activity
DON1 YDR273W Meiosis-specific component of the spindle pole body physical 1 1 1 Biochemical Activity
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 1 1 1 Biochemical Activity
RMD1 YDL001W Cytoplasmic protein required for sporulation physical 1 1 1 Biochemical Activity
NBA1 YOL070C Protein involved in axial bud site selection physical 1 1 1 Biochemical Activity
CHA4 YLR098C DNA binding transcriptional activator physical 1 1 1 Biochemical Activity
CHA4 YLR098C DNA binding transcriptional activator genetic 1 1 1 Negative Genetic
FMP16 YDR070C Protein of unknown function physical 1 1 1 Biochemical Activity
PEF1 YGR058W Penta-EF-hand protein physical 1 1 1 Biochemical Activity
AKR2 YOR034C Ankyrin repeat-containing protein genetic 1 1 1 Negative Genetic
SER33 YIL074C 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 1 1 1 Biochemical Activity
PRR1 YKL116C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
MGL2 YMR210W Monoacylglycerol and triacylglycerol lipase physical 1 1 1 Biochemical Activity
BLI1 YKL061W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Biochemical Activity
DOC1 YGL240W Processivity factor genetic 1 1 1 Dosage Lethality
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Synthetic Growth Defect
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family physical 1 1 1 Biochemical Activity
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
RGT1 YKL038W Glucose-responsive transcription factor physical 1 1 1 Biochemical Activity
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Biochemical Activity
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Biochemical Activity
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
BNI5 YNL166C Linker protein responsible for recruitment of myosin to the bud neck physical 1 1 1 Biochemical Activity
MCM3 YEL032W Protein involved in DNA replication physical 1 1 1 Biochemical Activity
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway genetic 1 1 1 Phenotypic Suppression
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Dosage Growth Defect
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
SIP5 YMR140W Protein of unknown function physical 1 1 1 Biochemical Activity
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TOM40 YMR203W Component of the TOM (translocase of outer membrane) complex physical 1 1 1 Biochemical Activity
DPH2 YKL191W Protein required for synthesis of diphthamide physical 1 1 1 Biochemical Activity
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Dosage Rescue
MBF1 YOR298C-A Transcriptional coactivator genetic 1 1 1 Positive Genetic
BAG7 YOR134W Rho GTPase activating protein (RhoGAP) physical 1 1 1 Biochemical Activity
GAP1 YKR039W General amino acid permease physical 1 1 1 Reconstituted Complex
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs physical 1 1 1 Biochemical Activity
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 1 1 1 Biochemical Activity
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 1 1 1 Positive Genetic
BUD6 YLR319C Actin- and formin-interacting protein physical 1 1 1 Biochemical Activity
GPB2 YAL056W Multistep regulator of cAMP-PKA signaling physical 1 1 1 Reconstituted Complex
GSY2 YLR258W Glycogen synthase physical 1 1 1 Biochemical Activity
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation genetic 1 1 1 Dosage Growth Defect
ALY1 YKR021W Alpha arrestin, substrate of calcineurin physical 1 1 1 Biochemical Activity
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Biochemical Activity
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Dosage Growth Defect
NNK1 YKL171W Protein kinase physical 1 1 1 Biochemical Activity
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 Biochemical Activity
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p physical 1 1 1 Biochemical Activity
HRI1 YLR301W Protein of unknown function that interacts with Sec72p and Hrr25p physical 1 1 1 Biochemical Activity
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 1 1 1 Biochemical Activity
OSH3 YHR073W Member of an oxysterol-binding protein family physical 1 1 1 Biochemical Activity
MGA1 YGR249W Protein similar to heat shock transcription factor physical 1 1 1 Biochemical Activity
AZF1 YOR113W Zinc-finger transcription factor physical 1 1 1 Biochemical Activity
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 1 1 1 Biochemical Activity
GAT1 YFL021W Transcriptional activator of nitrogen catabolite repression genes genetic 1 1 1 Dosage Rescue
HSV2 YGR223C Phosphatidylinositol 3,5-bisphosphate-binding protein physical 1 1 1 Biochemical Activity
TIF3 YPR163C Translation initiation factor eIF-4B genetic 1 1 1 Phenotypic Suppression
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Biochemical Activity
ENT5 YDR153C Protein containing an N-terminal epsin-like domain physical 1 1 1 Biochemical Activity
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Negative Genetic
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 1 1 1 Biochemical Activity
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit physical 1 1 1 Biochemical Activity
PXL1 YKR090W Protein that localizes to sites of polarized growth physical 1 1 1 Biochemical Activity
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
FLO8 YER109C Transcription factor genetic 1 1 1 Phenotypic Suppression
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 1 1 1 Biochemical Activity
FOX2 YKR009C 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase physical 1 1 1 Biochemical Activity
ORM2 YLR350W Protein that mediates sphingolipid homeostasis physical 1 1 1 Biochemical Activity
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis physical 1 1 1 Biochemical Activity
HBS1 YKR084C GTPase with similarity to translation release factors physical 1 1 1 Biochemical Activity
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport physical 1 1 1 Biochemical Activity
APM2 YHL019C Protein of unknown function physical 1 1 1 Biochemical Activity
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription physical 1 1 1 Biochemical Activity
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
CST26 YBR042C Acyltransferase physical 1 1 1 Biochemical Activity
ESBP6 YNL125C Protein with similarity to monocarboxylate permeases physical 1 1 1 Biochemical Activity
STE7 YDL159W Signal transducing MAP kinase kinase genetic 1 1 1 Phenotypic Suppression
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein physical 1 1 1 Biochemical Activity
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 1 1 1 Biochemical Activity
MAP1 YLR244C Methionine aminopeptidase physical 1 1 1 Biochemical Activity
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response physical 1 1 1 Biochemical Activity
SOL2 YCR073W-A Protein with a possible role in tRNA export physical 1 1 1 Biochemical Activity
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
PHR1 YOR386W DNA photolyase involved in photoreactivation physical 1 1 1 Biochemical Activity
NTH1 YDR001C Neutral trehalase, degrades trehalose genetic 1 1 1 Phenotypic Enhancement
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Dosage Rescue
AVT1 YJR001W Vacuolar transporter physical 1 1 1 Biochemical Activity
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase physical 1 1 1 Biochemical Activity
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Biochemical Activity
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase physical 1 1 1 Reconstituted Complex
NPY1 YGL067W NADH diphosphatase (pyrophosphatase) physical 1 1 1 Biochemical Activity
MET12 YPL023C Protein with MTHFR activity in vitro physical 1 1 1 Biochemical Activity
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Synthetic Growth Defect
RRP15 YPR143W Nucleolar protein physical 1 1 1 Biochemical Activity
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Biochemical Activity
MBR1 YKL093W Protein involved in mitochondrial functions and stress response physical 1 1 1 Biochemical Activity
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain physical 1 1 1 Biochemical Activity
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring physical 1 1 1 PCA
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p physical 1 1 1 Biochemical Activity
ECM3 YOR092W Non-essential protein of unknown function physical 1 1 1 Biochemical Activity
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis physical 1 1 1 Biochemical Activity
CYC7 YEL039C Cytochrome c isoform 2, expressed under hypoxic conditions physical 1 1 1 Biochemical Activity
PFK26 YIL107C 6-phosphofructo-2-kinase physical 1 1 1 Biochemical Activity
PHO13 YDL236W Conserved phosphatase acting as a metabolite repair enzyme physical 1 1 1 Biochemical Activity
STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein physical 1 1 1 Biochemical Activity
PTH2 YBL057C One of two mitochondrially-localized peptidyl-tRNA hydrolases physical 1 1 1 Biochemical Activity
SYF2 YGR129W Member of the NineTeen Complex (NTC) physical 1 1 1 Biochemical Activity
RIM4 YHL024W Putative RNA-binding protein physical 1 1 1 Biochemical Activity
ARO3 YDR035W 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase physical 1 1 1 Biochemical Activity
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 1 1 1 Biochemical Activity
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity physical 1 1 1 Biochemical Activity
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ABP140 YOR239W AdoMet-dependent tRNA methyltransferase and actin binding protein physical 1 1 1 Biochemical Activity
ALR2 YFL050C Probable Mg(2+) transporter physical 1 1 1 Biochemical Activity
ATG21 YPL100W Phosphoinositide binding protein physical 1 1 1 Biochemical Activity
CMK2 YOL016C Calmodulin-dependent protein kinase genetic 1 1 1 Negative Genetic
AVT3 YKL146W Vacuolar transporter physical 1 1 1 Biochemical Activity
ADD37 YMR184W Protein of unknown function physical 1 1 1 Biochemical Activity
DEG1 YFL001W tRNA:pseudouridine synthase physical 1 1 1 Biochemical Activity
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel physical 1 1 1 Biochemical Activity
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) physical 1 1 1 Biochemical Activity
IRC5 YFR038W Putative ATPase containing the DEAD/H helicase-related sequence motif physical 1 1 1 Biochemical Activity
MSN4 YKL062W Stress-responsive transcriptional activator physical 1 1 1 Biochemical Activity
NGL3 YML118W 3'-5' exonuclease specific for poly-A RNAs physical 1 1 1 Biochemical Activity
PHO91 YNR013C Low-affinity vacuolar phosphate transporter physical 1 1 1 Biochemical Activity
ENT4 YLL038C Protein of unknown function physical 1 1 1 Biochemical Activity
ICS2 YBR157C Protein of unknown function physical 1 1 1 Biochemical Activity
ORM1 YGR038W Protein that mediates sphingolipid homeostasis physical 1 1 1 Biochemical Activity
ISF1 YMR081C Serine-rich, hydrophilic protein physical 1 1 1 Biochemical Activity
POX1 YGL205W Fatty-acyl coenzyme A oxidase physical 1 1 1 Biochemical Activity
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) physical 1 1 1 Biochemical Activity
DGR2 YKL121W Protein of unknown function physical 1 1 1 Biochemical Activity
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis physical 1 1 1 Biochemical Activity
MLF3 YNL074C Serine-rich protein of unknown function physical 1 1 1 Biochemical Activity
RNH70 YGR276C 3'-5' exoribonuclease physical 1 1 1 Biochemical Activity
RGD3 YHR182W GTPase activating protein (GAP) for Rho3p, involved in cell polarity g physical 1 1 1 Biochemical Activity
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein physical 1 1 1 Biochemical Activity
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Biochemical Activity
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) physical 1 1 1 Biochemical Activity
RUD3 YOR216C Golgi matrix protein physical 1 1 1 Biochemical Activity
SSF2 YDR312W Protein required for ribosomal large subunit maturation physical 1 1 1 Biochemical Activity
TOM71 YHR117W Mitochondrial outer membrane protein physical 1 1 1 Biochemical Activity
OTU2 YHL013C Protein of unknown function physical 1 1 1 Biochemical Activity
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p physical 1 1 1 Biochemical Activity
RNY1 YPL123C Vacuolar RNase of the T(2) family physical 1 1 1 Biochemical Activity
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay physical 1 1 1 Biochemical Activity
RGM1 YMR182C Putative zinc finger DNA binding transcription factor physical 1 1 1 Biochemical Activity
SYG1 YIL047C Plasma membrane protein of unknown function physical 1 1 1 Biochemical Activity
TMA22 YJR014W Protein of unknown function physical 1 1 1 Biochemical Activity
SLZ1 YNL196C Sporulation-specific protein with a leucine zipper motif physical 1 1 1 Biochemical Activity
MPD1 YOR288C Member of the protein disulfide isomerase (PDI) family physical 1 1 1 Biochemical Activity
DIA1 YMR316W Protein of unknown function physical 1 1 1 Biochemical Activity
RKM4 YDR257C Ribosomal lysine methyltransferase physical 1 1 1 Biochemical Activity
STF2 YGR008C Protein involved in resistance to desiccation stress physical 1 1 1 Biochemical Activity
MIC26 YGR235C Component of the MICOS complex physical 1 1 1 Biochemical Activity
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 physical 1 1 1 Biochemical Activity
SKG1 YKR100C Transmembrane protein with a role in cell wall polymer composition physical 1 1 1 Biochemical Activity
TAG1 YLR173W Vacuolar membrane protein involved in termination of autophagy physical 1 1 1 Biochemical Activity
HUR1 YGL168W Protein with a role in DNA repair physical 1 1 1 Biochemical Activity
STR3 YGL184C Peroxisomal cystathionine beta-lyase physical 1 1 1 Biochemical Activity
SNX41 YDR425W Sorting nexin physical 1 1 1 Biochemical Activity
LCL1 YPL056C Putative protein of unknown function physical 1 1 1 Biochemical Activity
TIP41 YPR040W Tap42p-interacting protein physical 1 1 1 Biochemical Activity
PKP2 YGL059W Mitochondrial protein kinase physical 1 1 1 Biochemical Activity
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Positive Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
CYT2 YKL087C Cytochrome c1 heme lyase genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Phenotypic Suppression
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
TAT2 YOL020W High affinity tryptophan and tyrosine permease genetic 1 1 1 Dosage Growth Defect
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic