Standard name Systematic name Name description Description
HTB2 YBL002W Histone H2B Histone H2B; core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB1; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates reassembly after DNA replication, transcriptional activation, meiotic DSB formation and H3 methylation
Visualize the interactome of HTB2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 72

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.272 0.136 0.092
Mito 0.109 0.091 0.375
Nucleolus 0.112 0.189 0.382
Nucleus 0.898 0.894 0.789

GFP localization & abundance

GFP localization GFP abundance
nucleus 443000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HTB2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 8 4 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, FRET, Affinity Capture-Western
HTZ1 YOL012C Histone variant H2AZ physical 7 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 7 3 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 5 4 5 Co-purification, Co-purification, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
HTA2 YBL003C Histone H2A physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 4 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 3 2 3 Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-RNA
CSE4 YKL049C Centromeric histone H3-like protein physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BRE1 YDL074C E3 ubiquitin ligase physical 3 3 2 Biochemical Activity, Reconstituted Complex, Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MCM2 YBL023C Protein involved in DNA replication physical 3 3 1 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 2 2 2 Phenotypic Suppression, Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 2 2 Synthetic Growth Defect, Dosage Rescue
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 2 2 Dosage Growth Defect, Negative Genetic
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 2 2 2 Affinity Capture-MS, Biochemical Activity
CHZ1 YER030W Histone chaperone for Htz1p/H2A-H2B dimer physical 2 2 2 Affinity Capture-Western, Co-crystal Structure
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPO31 YOR116C RNA polymerase III largest subunit C160 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RAD16 YBR114W Nucleotide excision repair (NER) protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PSY2 YNL201C Subunit of protein phosphatase PP4 complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SWR1 YDR334W Swi2/Snf2-related ATPase physical 2 1 2 Reconstituted Complex, Reconstituted Complex
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) physical 2 1 2 Biochemical Activity, Biochemical Activity
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ABF2 YMR072W Mitochondrial DNA-binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HTB1 YDR224C Histone H2B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NHP6B YBR089C-A High-mobility group (HMG) protein physical 2 2 1 PCA, Reconstituted Complex
UBI4 YLL039C Ubiquitin physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 DNA to cDNA expression microarray evidence
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
BRE1 YDL074C E3 ubiquitin ligase regulation 1 1 1 qualitative western immunoblotting evidence
NHP6A YPR052C High-mobility group (HMG) protein regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
NHP6B YBR089C-A High-mobility group (HMG) protein regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression regulation 1 1 1 quantitative polymerase chain reaction evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 1 1 1 Affinity Capture-MS
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 Reconstituted Complex
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex physical 1 1 1 Affinity Capture-MS
HGH1 YGR187C Chaperone protein for translation factor eEF2 physical 1 1 1 Affinity Capture-MS
ASF1 YJL115W Nucleosome assembly factor physical 1 1 1 Affinity Capture-MS
BDF1 YLR399C BET family transcriptional regulator physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 1 1 1 Affinity Capture-MS
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-MS
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) physical 1 1 1 Reconstituted Complex
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon) physical 1 1 1 Affinity Capture-MS
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex physical 1 1 1 Affinity Capture-Western
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking physical 1 1 1 Affinity Capture-MS
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex physical 1 1 1 Reconstituted Complex
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex physical 1 1 1 Affinity Capture-MS
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling physical 1 1 1 Affinity Capture-MS
MOT1 YPL082C Essential protein involved in regulation of transcription physical 1 1 1 Affinity Capture-MS
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 1 1 1 Affinity Capture-MS
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
TOP1 YOL006C Topoisomerase I physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting physical 1 1 1 Affinity Capture-MS
PUF6 YDR496C Pumilio-homology domain protein physical 1 1 1 Affinity Capture-MS
YGR054W YGR054W Eukaryotic initiation factor eIF2A physical 1 1 1 Affinity Capture-MS
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes physical 1 1 1 Affinity Capture-MS
IGO1 YNL157W Protein required for initiation of G0 program physical 1 1 1 Affinity Capture-MS
YGR067C YGR067C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
MAG1 YER142C 3-methyl-adenine DNA glycosylase physical 1 1 1 Affinity Capture-MS
MIH1 YMR036C Protein tyrosine phosphatase physical 1 1 1 Affinity Capture-MS
INO4 YOL108C Transcription factor involved in phospholipid synthesis physical 1 1 1 Affinity Capture-MS
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Affinity Capture-MS
MIF2 YKL089W Centromeric CDEIII region binding protein physical 1 1 1 Affinity Capture-MS
INO80 YGL150C Nucleosome spacing factor physical 1 1 1 Affinity Capture-MS
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Dosage Growth Defect
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
ORC2 YBR060C Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
YCR043C YCR043C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Affinity Capture-MS
MIG1 YGL035C Transcription factor involved in glucose repression physical 1 1 1 Affinity Capture-MS
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 1 1 1 Affinity Capture-MS
ORC6 YHR118C Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
SEC28 YIL076W Epsilon-COP subunit of the coatomer physical 1 1 1 Affinity Capture-MS
SPC1 YJR010C-A Subunit of the signal peptidase complex (SPC) physical 1 1 1 Affinity Capture-MS
SWC7 YLR385C Protein of unknown function physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p physical 1 1 1 Affinity Capture-MS
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex physical 1 1 1 Affinity Capture-MS
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
ORC5 YNL261W Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase physical 1 1 1 Affinity Capture-MS
ORC4 YPR162C Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
MET6 YER091C Cobalamin-independent methionine synthase physical 1 1 1 Affinity Capture-MS
PSY4 YBL046W Regulatory subunit of protein phosphatase PP4 physical 1 1 1 Affinity Capture-MS
SRM1 YGL097W Nucleotide exchange factor for Gsp1p physical 1 1 1 Affinity Capture-MS
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 1 1 1 Affinity Capture-MS
NUC1 YJL208C Major mitochondrial nuclease physical 1 1 1 Affinity Capture-MS
SIR3 YLR442C Silencing protein physical 1 1 1 Affinity Capture-Western
NPL3 YDR432W RNA-binding protein physical 1 1 1 Affinity Capture-MS
NHP6A YPR052C High-mobility group (HMG) protein physical 1 1 1 PCA
VPS75 YNL246W NAP family histone chaperone physical 1 1 1 Reconstituted Complex
SRC1 YML034W Inner nuclear membrane protein physical 1 1 1 Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Affinity Capture-Western
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 1 1 1 Affinity Capture-MS
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex physical 1 1 1 Biochemical Activity
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Synthetic Rescue
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 Affinity Capture-MS
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) physical 1 1 1 Affinity Capture-MS
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 1 1 1 Affinity Capture-MS
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RPC10 YHR143W-A RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III physical 1 1 1 Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) physical 1 1 1 Affinity Capture-MS
RPC34 YNR003C RNA polymerase III subunit C34 physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Affinity Capture-MS
RPC53 YDL150W RNA polymerase III subunit C53 physical 1 1 1 Affinity Capture-MS
RTG2 YGL252C Sensor of mitochondrial dysfunction physical 1 1 1 Affinity Capture-MS
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RPC37 YKR025W RNA polymerase III subunit C37 physical 1 1 1 Affinity Capture-MS
RPC31 YNL151C RNA polymerase III subunit C31 physical 1 1 1 Affinity Capture-MS
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 1 1 1 Affinity Capture-MS
UME6 YDR207C Rpd3L histone deacetylase complex subunit physical 1 1 1 Affinity Capture-MS
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex physical 1 1 1 Affinity Capture-MS
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
YJL113W YJL113W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
MRPL22 YNL177C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 1 1 1 Affinity Capture-MS
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
POL4 YCR014C DNA polymerase IV physical 1 1 1 Affinity Capture-MS
SGM1 YJR134C Protein of unknown function physical 1 1 1 Affinity Capture-MS
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-MS
PIM1 YBL022C ATP-dependent Lon protease physical 1 1 1 Affinity Capture-MS
NSI1 YDR026C RNA polymerase I termination factor physical 1 1 1 Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 1 1 1 Affinity Capture-MS
SMC3 YJL074C Subunit of the multiprotein cohesin complex physical 1 1 1 Affinity Capture-MS
TOA2 YKL058W TFIIA small subunit physical 1 1 1 Affinity Capture-MS
RPC11 YDR045C RNA polymerase III subunit C11 physical 1 1 1 Affinity Capture-MS
RPC17 YJL011C RNA polymerase III subunit C17 physical 1 1 1 Affinity Capture-MS
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
SIP5 YMR140W Protein of unknown function physical 1 1 1 Affinity Capture-MS
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth physical 1 1 1 Affinity Capture-MS
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions physical 1 1 1 Affinity Capture-MS
MIP1 YOR330C Mitochondrial DNA polymerase gamma physical 1 1 1 Affinity Capture-MS
RPB8 YOR224C RNA polymerase subunit ABC14.5 physical 1 1 1 Affinity Capture-MS
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I physical 1 1 1 Affinity Capture-MS
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex physical 1 1 1 Affinity Capture-MS
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 1 1 1 Affinity Capture-MS
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
LSM1 YJL124C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties genetic 1 1 1 Synthetic Rescue
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SCM3 YDL139C Nonhistone component of centromeric chromatin physical 1 1 1 Reconstituted Complex
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) physical 1 1 1 Affinity Capture-Western
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex physical 1 1 1 Affinity Capture-Western
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RTT106 YNL206C Histone chaperone genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
OSW7 YFR039C Protein involved in outer spore wall assembly genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Negative Genetic
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
HTA2 YBL003C Histone H2A genetic 1 1 1 Synthetic Growth Defect
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Biochemical Activity
HEM13 YDR044W Coproporphyrinogen III oxidase physical 1 1 1 Affinity Capture-MS
ECM30 YLR436C Protein of unknown function physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-MS
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
HTB1 YDR224C Histone H2B genetic 1 1 1 Phenotypic Suppression
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex physical 1 1 1 Affinity Capture-MS
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Affinity Capture-MS
GIP2 YER054C Putative regulatory subunit of protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
FKH2 YNL068C Forkhead family transcription factor physical 1 1 1 Affinity Capture-MS
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E physical 1 1 1 Affinity Capture-MS
DUF1 YOL087C Ubiquitin-binding protein of unknown function physical 1 1 1 Affinity Capture-MS
CKI1 YLR133W Choline kinase physical 1 1 1 Affinity Capture-MS
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I physical 1 1 1 Affinity Capture-MS
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site physical 1 1 1 Affinity Capture-MS
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p physical 1 1 1 Affinity Capture-MS
BRF1 YGR246C TFIIIB B-related factor physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BNR1 YIL159W Formin physical 1 1 1 Affinity Capture-MS
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Two-hybrid
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase physical 1 1 1 Reconstituted Complex
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Phenotypic Suppression
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
DNF2 YDR093W Aminophospholipid translocase (flippase) physical 1 1 1 Affinity Capture-MS
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
GRS2 YPR081C Glycine-tRNA synthetase, not expressed under normal growth conditions physical 1 1 1 Affinity Capture-MS
EXO5 YBR163W Mitochondrial 5'-3' exonuclease and sliding exonuclease physical 1 1 1 Affinity Capture-MS