| VPS5 |
YOR069W |
Nexin-1 homolog |
physical |
15 |
6 |
13 |
Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-purification, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, PCA, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
8 |
3 |
6 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
physical |
7 |
4 |
6 |
Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, PCA, Affinity Capture-MS |
| COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
6 |
2 |
5 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
6 |
2 |
5 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
6 |
2 |
5 |
Positive Genetic, Positive Genetic, Phenotypic Suppression, Positive Genetic, Positive Genetic, Positive Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
6 |
2 |
4 |
Positive Genetic, Positive Genetic, Phenotypic Suppression, Positive Genetic, Positive Genetic, Positive Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
5 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
5 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western |
| SNX4 |
YJL036W |
Sorting nexin |
genetic |
4 |
3 |
4 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
4 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| BPH1 |
YCR032W |
Protein homologous to Chediak-Higashi syndrome and Beige proteins |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
4 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
physical |
3 |
3 |
3 |
Affinity Capture-Western, Affinity Capture-MS, PCA |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Positive Genetic, Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
3 |
3 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect, Positive Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HXT10 |
YFL011W |
Hexose transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| CHS1 |
YNL192W |
Chitin synthase I |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Growth Defect |
| MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBC6 |
YER100W |
Ubiquitin-conjugating enzyme involved in ERAD |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FCF1 |
YDR339C |
PINc domain endonuclease |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TVP18 |
YMR071C |
Integral membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| YGL260W |
YGL260W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SYN8 |
YAL014C |
Endosomal SNARE related to mammalian syntaxin 8 |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KEX1 |
YGL203C |
Cell death protease essential for hypochlorite-induced apoptosis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PXP1 |
YEL020C |
Peroxisomal matrix protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ALK2 |
YBL009W |
Atypical protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRX20 |
YFR045W |
Putative mitochondrial transport protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| YIF1 |
YNL263C |
Integral membrane protein |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
| YIP1 |
YGR172C |
Integral membrane protein |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
| BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SAL1 |
YNL083W |
ADP/ATP transporter |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PPR1 |
YLR014C |
Zinc finger transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ARG81 |
YML099C |
Zinc finger transcription factor involved in arginine-responsive genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HAA1 |
YPR008W |
Transcriptional activator involved in adaptation to weak acid stress |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RGT1 |
YKL038W |
Glucose-responsive transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM22 |
YJR135C |
Outer kinetochore protein and component of the Ctf3 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS21 |
YEL019C |
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MTR4 |
YJL050W |
RNA duplex-sensing translocase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHC1 |
YGL206C |
Clathrin heavy chain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRP1 |
YOL123W |
Subunit of cleavage factor I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KGD1 |
YIL125W |
Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMG1 |
YCR046C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD3 |
YCL014W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG18 |
YFR021W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLH2 |
YLR035C |
Protein involved in mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Two-hybrid |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECM30 |
YLR436C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PIB1 |
YDR313C |
RING-type ubiquitin ligase of the endosomal and vacuolar membranes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAS1 |
YOR101W |
GTPase involved in G-protein signaling in adenylate cyclase activation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AYR1 |
YIL124W |
Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APT1 |
YML022W |
Adenine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARA1 |
YBR149W |
NADP+ dependent arabinose dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APE2 |
YKL157W |
Aminopeptidase yscII |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP3 |
YHR065C |
Protein involved in rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC43 |
YGL155W |
Beta subunit of geranylgeranyltransferase type I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMN1 |
YDR236C |
Riboflavin kinase, produces riboflavin monophosphate (FMN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPG1 |
YNR032W |
Serine protein phosphatase involved in formation of FAR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
physical |
1 |
1 |
1 |
PCA |
| CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT53 |
YNL093W |
Stress-induced Rab family GTPase |
physical |
1 |
1 |
1 |
Two-hybrid |
| YIP4 |
YGL198W |
Protein that interacts with Rab GTPases |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT7 |
YML001W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKR018C |
YKR018C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR196C-A |
YBR196C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS25 |
YJR102C |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL075C |
YKL075C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPS1 |
YLR120C |
Aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL081W |
YGL081W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR316C-A |
YOR316C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS28 |
YPL065W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
physical |
1 |
1 |
1 |
PCA |
| THG1 |
YGR024C |
tRNAHis guanylyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG8 |
YBL078C |
Ub-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP150 |
YJL159W |
O-mannosylated heat shock protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNX4 |
YJL036W |
Sorting nexin |
physical |
1 |
1 |
1 |
Two-hybrid |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATC1 |
YDR184C |
Nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPH6 |
YLR143W |
Diphthamide synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPA2 |
YLL021W |
Component of the polarisome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF3 |
YDL194W |
Plasma membrane low glucose sensor, regulates glucose transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFG5 |
YMR238W |
Putative mannosidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERF2 |
YLR246W |
Subunit of a palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBN1 |
YCL052C |
Component of glycosylphosphatidylinositol-mannosyltransferase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FRA1 |
YLL029W |
Protein involved in negative regulation of iron regulon transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| INP1 |
YMR204C |
Peripheral membrane protein of peroxisomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
physical |
1 |
1 |
1 |
Two-hybrid |
| PEX1 |
YKL197C |
AAA-peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC22 |
YEL001C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUK1 |
YDR454C |
Guanylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CUE3 |
YGL110C |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPT1 |
YGR123C |
Protein serine/threonine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUK1 |
YPL070W |
Guanine nucleotide exchange factor (GEF) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CGI121 |
YML036W |
Component of the EKC/KEOPS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APS1 |
YLR170C |
Small subunit of the clathrin-associated adaptor complex AP-1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANY1 |
YMR010W |
Protein involved in phospholipid flippase function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADE12 |
YNL220W |
Adenylosuccinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COA3 |
YJL062W-A |
Mitochondrial protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSF3 |
YOL146W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NVJ3 |
YDR179W-A |
Protein with a potential role in tethering ER and vacuoles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LDB19 |
YOR322C |
Alpha-arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAA1 |
YLR088W |
Subunit of the GPI:protein transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HST4 |
YDR191W |
NAD(+)-dependent protein deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM34 |
YMR003W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCY2 |
YER056C |
Purine-cytosine permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERS1 |
YCR075C |
Protein involved in cystine transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO19 |
YPL130W |
Meiosis-specific prospore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNR2 |
YKL151C |
Widely-conserved NADHX dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP32 |
YPL280W |
Possible chaperone and cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BSC4 |
YNL269W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVT5 |
YBL089W |
Putative transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET13 |
YGL125W |
Major isozyme of methylenetetrahydrofolate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OAZ1 |
YPL052W |
Regulator of ornithine decarboxylase Spe1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLD1 |
YPR109W |
Component of Dsc E3 ligase complex in Golgi and endosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCV2 |
YMR189W |
P subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROT2 |
YBR229C |
Glucosidase II catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPT14 |
YPL175W |
UDP-glycosyltransferase subunit of the GPI-GnT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCV1 |
YDR019C |
T subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AIM36 |
YMR157C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECM14 |
YHR132C |
Conserved fungal protein with similarity to zinc carboxypeptidases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP1 |
YDL122W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC10 |
YBR265W |
3-ketosphinganine reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIR3 |
YIL011W |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHH3 |
YMR118C |
Putative mitochondrial inner membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
