GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
GCN5	YGR252W	Catalytic subunit of ADA and SAGA histone acetyltransferase complexes	physical	49	6	36	Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification
NGG1	YDR176W	Subunit of chromatin modifying histone acetyltransferase complexes	physical	39	6	27	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-Western
SPT7	YBR081C	Subunit of the SAGA transcriptional regulatory complex	physical	31	3	25	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SPT20	YOL148C	Subunit of the SAGA transcriptional regulatory complex	physical	22	6	18	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Co-localization, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-RNA, Affinity Capture-MS, Co-purification
TAF5	YBR198C	Subunit (90 kDa) of TFIID and SAGA complexes	physical	20	3	18	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-purification, Affinity Capture-Western
UBP8	YMR223W	Ubiquitin-specific protease component of the SAGA acetylation complex	physical	19	3	15	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
TAF6	YGL112C	Subunit (60 kDa) of TFIID and SAGA complexes	physical	18	4	16	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
SGF73	YGL066W	Subunit of DUBm module of SAGA and SLIK	physical	18	3	12	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Co-purification
SPT8	YLR055C	Subunit of the SAGA transcriptional regulatory complex	physical	17	4	13	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HFI1	YPL254W	Adaptor protein required for structural integrity of the SAGA complex	physical	17	3	13	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
TAF12	YDR145W	Subunit (61/68 kDa) of TFIID and SAGA complexes	physical	16	4	15	Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
TRA1	YHR099W	Subunit of SAGA and NuA4 histone acetyltransferase complexes	physical	16	2	15	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SPT3	YDR392W	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes	physical	15	4	15	Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification
SGF29	YCL010C	Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes	physical	14	3	11	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
TAF10	YDR167W	Subunit (145 kDa) of TFIID and SAGA complexes	physical	13	3	13	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SGF11	YPL047W	Integral subunit of SAGA histone acetyltransferase complex	physical	11	1	8	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TAF9	YMR236W	Subunit (17 kDa) of TFIID and SAGA complexes	physical	10	3	8	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SUS1	YBR111W-A	Global transcriptional regulator, component of SAGA, TREX-2 complexes	physical	8	2	6	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SAS3	YBL052C	Histone acetyltransferase catalytic subunit of NuA3 complex	genetic	7	3	4	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Negative Genetic
SAP30	YMR263W	Component of Rpd3L histone deacetylase complex	genetic	6	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
EAF6	YJR082C	Subunit of the NuA4 acetyltransferase complex	genetic	5	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
PHO23	YNL097C	Component of the Rpd3L histone deacetylase complex	genetic	5	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
GCN4	YEL009C	bZIP transcriptional activator of amino acid biosynthetic genes	physical	4	2	4	Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
SGF73	YGL066W	Subunit of DUBm module of SAGA and SLIK	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SGF11	YPL047W	Integral subunit of SAGA histone acetyltransferase complex	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
BEM4	YPL161C	Protein involved in establishment of cell polarity and bud emergence	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
DEP1	YAL013W	Component of the Rpd3L histone deacetylase complex	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ELP2	YGR200C	Subunit of Elongator complex	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ELP6	YMR312W	Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
IXR1	YKL032C	Transcriptional repressor that regulates hypoxic genes during normoxia	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
LGE1	YPL055C	Protein involved in histone H2B ubiquitination	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
NTO1	YPR031W	Subunit of the NuA3 histone acetyltransferase complex	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
PKR1	YMR123W	V-ATPase assembly factor	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
PRE9	YGR135W	Alpha 3 subunit of the 20S proteasome	genetic	4	2	3	Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
STE50	YCL032W	Adaptor protein for various signaling pathways	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
YNG1	YOR064C	Subunit of the NuA3 histone acetyltransferase complex	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
YTA7	YGR270W	Chromatin-binding ATPase that regulates histone gene expression	genetic	4	2	3	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
AHC1	YOR023C	Subunit of the Ada histone acetyltransferase complex	physical	4	3	2	Reconstituted Complex, Co-purification, Affinity Capture-MS, Affinity Capture-MS
SPT8	YLR055C	Subunit of the SAGA transcriptional regulatory complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ARP4	YJL081C	Nuclear actin-related protein involved in chromatin remodeling	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CDC20	YGL116W	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF1	YDR359C	Component of the NuA4 histone acetyltransferase complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF3	YPR023C	Component of the Rpd3S histone deacetylase complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF5	YEL018W	Non-essential subunit of the NuA4 acetyltransferase complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EAF7	YNL136W	Subunit of the NuA4 histone acetyltransferase complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
ELP3	YPL086C	Subunit of Elongator complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
EPL1	YFL024C	Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex	genetic	4	1	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ESA1	YOR244W	Catalytic subunit of the histone acetyltransferase complex (NuA4)	genetic	4	1	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
NUT1	YGL151W	Component of the RNA polymerase II mediator complex	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RPD3	YNL330C	Histone deacetylase, component of both the Rpd3S and Rpd3L complexes	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
RTT109	YLL002W	Histone acetyltransferase	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SIN3	YOL004W	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SWC4	YGR002C	Component of the Swr1p complex that incorporates Htz1p into chromatin	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
YAF9	YNL107W	Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes	genetic	4	1	1	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
YNG2	YHR090C	Subunit of NuA4, an essential histone acetyltransferase complex	genetic	4	1	1	Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
UBP8	YMR223W	Ubiquitin-specific protease component of the SAGA acetylation complex	genetic	3	3	3	Negative Genetic, Synthetic Rescue, Synthetic Growth Defect
TAF1	YGR274C	TFIID subunit, involved in RNA pol II transcription initiation	physical	3	2	3	Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
GAL4	YPL248C	DNA-binding transcription factor required for activating GAL genes	physical	3	2	3	Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
ADA2	YDR448W	Transcription coactivator	physical	3	1	3	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RXT2	YBR095C	Component of the histone deacetylase Rpd3L complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
BRE1	YDL074C	E3 ubiquitin ligase	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
IKI3	YLR384C	Subunit of Elongator complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SDS3	YIL084C	Component of the Rpd3L histone deacetylase complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SNT1	YCR033W	Set3C histone deacetylase scaffold	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
SWD1	YAR003W	Subunit of the COMPASS (Set1C) complex	genetic	3	2	2	Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
AHC2	YCR082W	Component of the ADA histone acetyltransferase complex	physical	3	1	2	Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HTZ1	YOL012C	Histone variant H2AZ	genetic	3	1	2	Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
NOT5	YPR072W	Component of the CCR4-NOT core complex, involved in mRNA decapping	physical	3	2	1	Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-RNA
CWP1	YKL096W	Cell wall mannoprotein that localizes to birth scars of daughter cells	regulation	2	2	2	chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
HHT1	YBR010W	Histone H3	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
HTA1	YDR225W	Histone H2A	physical	2	2	2	Affinity Capture-MS, Co-purification
SAC3	YDR159W	mRNA export factor	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
THP1	YOL072W	Nuclear pore-associated protein	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
TRA1	YHR099W	Subunit of SAGA and NuA4 histone acetyltransferase complexes	genetic	2	2	2	Synthetic Growth Defect, Synthetic Lethality
SPT15	YER148W	TATA-binding protein (TBP)	physical	2	2	2	Affinity Capture-MS, Affinity Capture-Western
SWI1	YPL016W	Subunit of the SWI/SNF chromatin remodeling complex	genetic	2	2	2	Synthetic Growth Defect, Synthetic Lethality
SRB2	YHR041C	Subunit of the RNA polymerase II mediator complex	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
HDA1	YNL021W	Catalytic subunit of class II HDA1 histone deacetylase complex	genetic	2	2	2	Positive Genetic, Synthetic Rescue
SWR1	YDR334W	Swi2/Snf2-related ATPase	genetic	2	2	2	Synthetic Rescue, Negative Genetic
MED7	YOL135C	Subunit of the RNA polymerase II mediator complex	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
SRB6	YBR253W	Subunit of the RNA polymerase II mediator complex	physical	2	1	2	Affinity Capture-MS, Affinity Capture-MS
SPC25	YER018C	Component of the kinetochore-associated Ndc80 complex	physical	2	1	2	Two-hybrid, Two-hybrid
SWC5	YBR231C	Component of the SWR1 complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PAT1	YCR077C	Deadenylation-dependent mRNA-decapping factor	genetic	2	1	2	Negative Genetic, Negative Genetic
MAF1	YDR005C	Highly conserved negative regulator of RNA polymerase III	genetic	2	1	2	Negative Genetic, Negative Genetic
SLX8	YER116C	Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex	genetic	2	1	2	Negative Genetic, Negative Genetic
RTR1	YER139C	Dual specificity protein phosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
IES1	YFL013C	Subunit of the INO80 chromatin remodeling complex	genetic	2	1	2	Negative Genetic, Negative Genetic
KAP122	YGL016W	Karyopherin beta	genetic	2	1	2	Negative Genetic, Negative Genetic
DBF2	YGR092W	Ser/Thr kinase involved in transcription and stress response	genetic	2	1	2	Negative Genetic, Negative Genetic
DOA1	YKL213C	WD-repeat protein involved in ubiquitin-mediated protein degradation	genetic	2	1	2	Negative Genetic, Negative Genetic
KTI12	YKL110C	Protein that plays a role in modification of tRNA wobble nucleosides	genetic	2	1	2	Negative Genetic, Negative Genetic
BRE2	YLR015W	Subunit of COMPASS (Set1C) complex	genetic	2	1	2	Negative Genetic, Negative Genetic
CKI1	YLR133W	Choline kinase	genetic	2	1	2	Negative Genetic, Negative Genetic
NMD4	YLR363C	Protein that may be involved in nonsense-mediated mRNA decay	genetic	2	1	2	Negative Genetic, Negative Genetic
VID22	YLR373C	G-quadruplex (G4) DNA binding protein	genetic	2	1	2	Negative Genetic, Negative Genetic
VIP1	YLR410W	Bifunctional inositol pyrophosphate kinase and phosphatase	genetic	2	1	2	Negative Genetic, Negative Genetic
TSA1	YML028W	Thioredoxin peroxidase	genetic	2	1	2	Negative Genetic, Negative Genetic
UBC7	YMR022W	Ubiquitin conjugating enzyme	genetic	2	1	2	Negative Genetic, Negative Genetic
SSO2	YMR183C	Plasma membrane t-SNARE	genetic	2	1	2	Negative Genetic, Negative Genetic
DUF1	YOL087C	Ubiquitin-binding protein of unknown function	genetic	2	1	2	Negative Genetic, Negative Genetic
POC4	YPL144W	Component of a heterodimeric Poc4p-Irc25p chaperone	genetic	2	1	2	Negative Genetic, Negative Genetic
MAK3	YPR051W	Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT)	genetic	2	1	2	Negative Genetic, Negative Genetic
TKL1	YPR074C	Transketolase	genetic	2	1	2	Negative Genetic, Negative Genetic
MOG1	YJR074W	Conserved nuclear protein that interacts with GTP-Gsp1p	physical	2	2	1	Affinity Capture-Western, Affinity Capture-MS
SPT7	YBR081C	Subunit of the SAGA transcriptional regulatory complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HFI1	YPL254W	Adaptor protein required for structural integrity of the SAGA complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
HHT1	YBR010W	Histone H3	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SPT20	YOL148C	Subunit of the SAGA transcriptional regulatory complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SPT3	YDR392W	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
TAF9	YMR236W	Subunit (17 kDa) of TFIID and SAGA complexes	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
MED1	YPR070W	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
SIR2	YDL042C	Conserved NAD+ dependent histone deacetylase of the Sirtuin family	physical	2	1	1	Affinity Capture-Western, Affinity Capture-Western
BDF1	YLR399C	BET family transcriptional regulator	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
BUR2	YLR226W	Cyclin for the Sgv1p (Bur1p) protein kinase	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
CDH1	YGL003C	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
CSE2	YNR010W	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
DST1	YGL043W	General transcription elongation factor TFIIS	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
ELP4	YPL101W	Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
FET3	YMR058W	Ferro-O2-oxidoreductase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
FTR1	YER145C	High affinity iron permease	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
GRR1	YJR090C	F-box protein component of an SCF ubiquitin-ligase complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
IES3	YLR052W	Subunit of the INO80 chromatin remodeling complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
IPP1	YBR011C	Cytoplasmic inorganic pyrophosphatase (PPase)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ISW1	YBR245C	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ISW2	YOR304W	ATP-dependent DNA translocase involved in chromatin remodeling	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MED2	YDL005C	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
PAF1	YBR279W	Component of the Paf1p complex involved in transcription elongation	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
PEX32	YBR168W	Peroxisomal integral membrane protein	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
PHO2	YDL106C	Homeobox transcription factor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RAD6	YGL058W	Ubiquitin-conjugating enzyme (E2)	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RIC1	YLR039C	Protein involved in retrograde transport to the cis-Golgi network	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
RSC2	YLR357W	Component of the RSC chromatin remodeling complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SIN4	YNL236W	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SOH1	YGL127C	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SSN2	YDR443C	Subunit of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SSN3	YPL042C	Component of the RNA polymerase II mediator complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SSN8	YNL025C	Cyclin-like component of RNA polymerase II holoenzyme	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
STE14	YDR410C	Farnesyl cysteine-carboxyl methyltransferase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SWD3	YBR175W	Essential subunit of the COMPASS (Set1C) complex	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
SWI6	YLR182W	Transcription cofactor	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VMA1	YDL185W	Subunit A of the V1 peripheral membrane domain of V-ATPase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VMA2	YBR127C	Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VMA22	YHR060W	Protein that is required for vacuolar H+-ATPase (V-ATPase) function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VMA7	YGR020C	Subunit F of the V1 peripheral membrane domain of V-ATPase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VMA8	YEL051W	Subunit D of the V1 peripheral membrane domain of V-ATPase	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
VPH2	YKL119C	Integral membrane protein required for V-ATPase function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
WHI5	YOR083W	Repressor of G1 transcription	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
MYG1	YER156C	Protein involved in mitochondrial function	genetic	2	1	1	Synthetic Growth Defect, Synthetic Growth Defect
ACS2	YLR153C	Acetyl-coA synthetase isoform	genetic	2	1	1	Synthetic Lethality, Synthetic Lethality
FKH1	YIL131C	Forkhead family transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
FKH2	YNL068C	Forkhead family transcription factor	regulation	1	1	1	ChEC-Seq experiments
RGR1	YLR071C	Subunit of the RNA polymerase II mediator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YAP6	YDR259C	Basic leucine zipper (bZIP) transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TFC7	YOR110W	RNA pol III transcription initiation factor complex (TFIIIC) subunit	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
FHL1	YPR104C	Regulator of ribosomal protein (RP) transcription	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PDR1	YGL013C	Transcription factor that regulates the pleiotropic drug response	regulation	1	1	1	DNA to cDNA expression microarray evidence
PGK1	YCR012W	3-phosphoglycerate kinase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
BAP3	YDR046C	Amino acid permease	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YPP1	YGR198W	Cargo-transport protein involved in endocytosis	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YGP1	YNL160W	Cell wall-related secretory glycoprotein	regulation	1	1	1	DNA to cDNA expression microarray evidence
RTT105	YER104W	Chaperone for Replication Protein A complex (RPA)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HMO1	YDR174W	Chromatin associated high mobility group (HMG) family member	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CIT2	YCR005C	Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
EIS1	YMR031C	Component of the eisosome required for proper eisosome assembly	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CPR1	YDR155C	Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ALD6	YPL061W	Cytosolic aldehyde dehydrogenase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HMX1	YLR205C	ER localized heme oxygenase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PGA2	YNL149C	Essential protein required for maturation of Gas1p and Pho8p	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SWD3	YBR175W	Essential subunit of the COMPASS (Set1C) complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
FBA1	YKL060C	Fructose 1,6-bisphosphate aldolase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TDH2	YJR009C	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SUL2	YLR092W	High affinity sulfate permease	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ZRT1	YGL255W	High-affinity zinc transporter of the plasma membrane	regulation	1	1	1	DNA to cDNA expression microarray evidence
HHT2	YNL031C	Histone H3	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SSA2	YLL024C	HSP70 family ATP-binding protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
FES1	YBR101C	Hsp70 (Ssa1p) nucleotide exchange factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HSP82	YPL240C	Hsp90 chaperone	regulation	1	1	1	DNA to cDNA expression microarray evidence
FIT2	YOR382W	Mannoprotein that is incorporated into the cell wall	regulation	1	1	1	DNA to cDNA expression microarray evidence
UPS2	YLR168C	Mitochondrial intermembrane space protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CTH1	YDR151C	mRNA binding protein, member of the CCCH zinc finger family	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HSP30	YCR021C	Negative regulator of the H(+)-ATPase Pma1p	regulation	1	1	1	DNA to cDNA expression microarray evidence
DSK2	YMR276W	Nuclear-enriched ubiquitin-like polyubiquitin-binding protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
STE6	YKL209C	Plasma membrane ATP-binding cassette (ABC) transporter	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
NCW1	YMR122W-A	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YLR108C	YLR108C	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SNA2	YDR525W-A	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YMR262W	YMR262W	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
AIM26	YKL037W	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ATG41	YPL250C	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PMP2	YEL017C-A	Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RTS3	YGR161C	Putative component of the protein phosphatase type 2A complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YLR412C-A	YLR412C-A	Putative protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YGR146C-A	YGR146C-A	Putative protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YGR161W-C	YGR161W-C	Putative protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PYC1	YGL062W	Pyruvate carboxylase isoform	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YOP1	YPR028W	Reticulon-interacting protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HSP42	YDR171W	Small heat shock protein (sHSP) with chaperone activity	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ERG1	YGR175C	Squalene epoxidase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
GID8	YMR135C	Subunit of GID Complex, binds strongly to central component Vid30p	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PHB1	YGR132C	Subunit of the prohibitin complex (Phb1p-Phb2p)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TAD2	YJL035C	Subunit of tRNA-specific adenosine-34 deaminase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
GAT1	YFL021W	Transcriptional activator of nitrogen catabolite repression genes	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
IXR1	YKL032C	Transcriptional repressor that regulates hypoxic genes during normoxia	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
UBC4	YBR082C	Ubiquitin-conjugating enzyme (E2)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
BTN2	YGR142W	v-SNARE binding protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ASG1	YIL130W	Zinc cluster protein proposed to be a transcriptional regulator	regulation	1	1	1	DNA to cDNA expression microarray evidence
YRM1	YOR172W	Zinc finger transcription factor involved in multidrug resistance	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SPN1	YPR133C	Protein involved in RNA polymerase II transcription	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
NDT80	YHR124W	Meiosis-specific transcription factor	regulation	1	1	1	DNA to cDNA expression microarray evidence
AAH1	YNL141W	Adenine deaminase (adenine aminohydrolase)	genetic	1	1	1	Phenotypic Suppression
GCN5	YGR252W	Catalytic subunit of ADA and SAGA histone acetyltransferase complexes	genetic	1	1	1	Synthetic Rescue
PCF11	YDR228C	mRNA 3' end processing factor	physical	1	1	1	Two-hybrid
CDC31	YOR257W	Calcium-binding component of the spindle pole body (SPB) half-bridge	physical	1	1	1	Affinity Capture-MS
CDC36	YDL165W	Component of the CCR4-NOT core complex, involved in mRNA decapping	physical	1	1	1	Affinity Capture-Western
ADR1	YDR216W	Carbon source-responsive zinc-finger transcription factor	physical	1	1	1	Affinity Capture-Western
CTI6	YPL181W	Component of the Rpd3L histone deacetylase complex	physical	1	1	1	Affinity Capture-Western
IRE1	YHR079C	Serine-threonine kinase and endoribonuclease	physical	1	1	1	Reconstituted Complex
SWI5	YDR146C	Transcription factor that recruits Mediator and Swi/Snf complexes	physical	1	1	1	Co-localization
MYO4	YAL029C	Type V myosin motor involved in actin-based transport of cargos	physical	1	1	1	Co-localization
SNF2	YOR290C	Catalytic subunit of the SWI/SNF chromatin remodeling complex	physical	1	1	1	Co-localization
SNF2	YOR290C	Catalytic subunit of the SWI/SNF chromatin remodeling complex	genetic	1	1	1	Synthetic Growth Defect
CHD1	YER164W	Chromatin remodeler that regulates various aspects of transcription	physical	1	1	1	Affinity Capture-MS
YAP1	YML007W	Basic leucine zipper (bZIP) transcription factor	physical	1	1	1	Affinity Capture-MS
MED1	YPR070W	Subunit of the RNA polymerase II mediator complex	physical	1	1	1	Affinity Capture-MS
HOG1	YLR113W	Mitogen-activated protein kinase involved in osmoregulation	physical	1	1	1	Affinity Capture-Western
PRP45	YAL032C	Protein required for pre-mRNA splicing	physical	1	1	1	Two-hybrid
RBG1	YAL036C	Member of the DRG family of GTP-binding proteins	physical	1	1	1	Two-hybrid
TRX3	YCR083W	Mitochondrial thioredoxin	physical	1	1	1	Two-hybrid
RPC11	YDR045C	RNA polymerase III subunit C11	physical	1	1	1	Two-hybrid
HSP42	YDR171W	Small heat shock protein (sHSP) with chaperone activity	physical	1	1	1	Two-hybrid
BTN2	YGR142W	v-SNARE binding protein	physical	1	1	1	Two-hybrid
SKI6	YGR195W	Exosome non-catalytic core component	physical	1	1	1	Two-hybrid
APL6	YGR261C	Beta3-like subunit of the yeast AP-3 complex	physical	1	1	1	Two-hybrid
MRP4	YHL004W	Mitochondrial ribosomal protein of the small subunit	physical	1	1	1	Two-hybrid
YHR022C	YHR022C	Putative protein of unknown function	physical	1	1	1	Two-hybrid
RPC17	YJL011C	RNA polymerase III subunit C17	physical	1	1	1	Two-hybrid
BIT61	YJL058C	Subunit of TORC2 membrane-associated complex	physical	1	1	1	Two-hybrid
MRX12	YJR003C	Protein that associates with mitochondrial ribosome	physical	1	1	1	Two-hybrid
SPP382	YLR424W	Essential protein that forms a dimer with Ntr2p	physical	1	1	1	Two-hybrid
VPS71	YML041C	Nucleosome-binding component of the SWR1 complex	physical	1	1	1	Two-hybrid
PRE5	YMR314W	Alpha 6 subunit of the 20S proteasome	physical	1	1	1	Two-hybrid
YPL077C	YPL077C	Putative protein of unknown function	physical	1	1	1	Two-hybrid
TFB2	YPL122C	Subunit of TFIIH and nucleotide excision repair factor 3 complexes	physical	1	1	1	Two-hybrid
ISU1	YPL135W	Conserved protein of the mitochondrial matrix	physical	1	1	1	Two-hybrid
ISU1	YPL135W	Conserved protein of the mitochondrial matrix	genetic	1	1	1	Negative Genetic
VPS4	YPR173C	AAA-ATPase involved in multivesicular body (MVB) protein sorting	physical	1	1	1	Two-hybrid
MOT1	YPL082C	Essential protein involved in regulation of transcription	physical	1	1	1	Affinity Capture-Western
RPO21	YDL140C	RNA polymerase II largest subunit B220	physical	1	1	1	Affinity Capture-Western
IFH1	YLR223C	Coactivator, regulates transcription of ribosomal protein (RP) genes	physical	1	1	1	Reconstituted Complex
RCK1	YGL158W	Protein kinase involved in oxidative stress response	physical	1	1	1	Affinity Capture-MS
RTG3	YBL103C	bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways	physical	1	1	1	Affinity Capture-MS
RTG3	YBL103C	bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways	genetic	1	1	1	Negative Genetic
SLT2	YHR030C	Serine/threonine MAP kinase	physical	1	1	1	Affinity Capture-Western
RPO31	YOR116C	RNA polymerase III largest subunit C160	physical	1	1	1	Affinity Capture-MS
SAN1	YDR143C	Ubiquitin-protein ligase	physical	1	1	1	Affinity Capture-MS
TUB2	YFL037W	Beta-tubulin	physical	1	1	1	Affinity Capture-MS
SUB2	YDL084W	Component of the TREX complex required for nuclear mRNA export	physical	1	1	1	Affinity Capture-MS
PRS1	YKL181W	5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase	physical	1	1	1	Affinity Capture-MS
TEF4	YKL081W	Gamma subunit of translational elongation factor eEF1B	physical	1	1	1	Affinity Capture-MS
FAA4	YMR246W	Long chain fatty acyl-CoA synthetase	physical	1	1	1	Affinity Capture-MS
STE12	YHR084W	Transcription factor that is activated by a MAPK signaling cascade	physical	1	1	1	Affinity Capture-MS
MAE1	YKL029C	Mitochondrial malic enzyme	physical	1	1	1	Affinity Capture-MS
CDC48	YDL126C	AAA ATPase with protein-unfoldase activity	physical	1	1	1	Affinity Capture-MS
BMH2	YDR099W	14-3-3 protein, minor isoform	physical	1	1	1	Affinity Capture-MS
BMH1	YER177W	14-3-3 protein, major isoform	physical	1	1	1	Affinity Capture-MS
RPT2	YDL007W	ATPase of the 19S regulatory particle of the 26S proteasome	physical	1	1	1	Affinity Capture-MS
CCT8	YJL008C	Subunit of the cytosolic chaperonin Cct ring complex	physical	1	1	1	Affinity Capture-MS
RPL12A	YEL054C	Ribosomal 60S subunit protein L12A	physical	1	1	1	Affinity Capture-MS
TFB3	YDR460W	Subunit of TFIIH and nucleotide excision repair factor 3 complexes	physical	1	1	1	Affinity Capture-MS
HSP60	YLR259C	Tetradecameric mitochondrial chaperonin	physical	1	1	1	Affinity Capture-MS
DIT1	YDR403W	Sporulation-specific enzyme required for spore wall maturation	physical	1	1	1	Affinity Capture-MS
RPL2A	YFR031C-A	Ribosomal 60S subunit protein L2A	physical	1	1	1	Affinity Capture-MS
RVB2	YPL235W	ATP-dependent DNA helicase, also known as reptin	physical	1	1	1	Affinity Capture-MS
CLC1	YGR167W	Clathrin light chain	physical	1	1	1	Affinity Capture-MS
TIM13	YGR181W	Mitochondrial intermembrane space protein	physical	1	1	1	Affinity Capture-MS
SSC1	YJR045C	Hsp70 family ATPase	physical	1	1	1	Affinity Capture-MS
RPP2A	YOL039W	Ribosomal protein P2 alpha	physical	1	1	1	Affinity Capture-MS
RPS21A	YKR057W	Protein component of the small (40S) ribosomal subunit	physical	1	1	1	Affinity Capture-MS
TDH2	YJR009C	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2	physical	1	1	1	Affinity Capture-MS
SSA1	YAL005C	ATPase involved in protein folding and NLS-directed nuclear transport	physical	1	1	1	Affinity Capture-MS
SEM1	YDR363W-A	19S proteasome regulatory particle lid subcomplex component	physical	1	1	1	Affinity Capture-Western
SPT10	YJL127C	Histone H3 acetylase with a role in transcriptional regulation	physical	1	1	1	Affinity Capture-MS
VAM6	YDL077C	Guanine nucleotide exchange factor for the GTPase Gtr1p	physical	1	1	1	Affinity Capture-MS
CRM1	YGR218W	Nuclear export factor, exportin	physical	1	1	1	Affinity Capture-MS
RPC82	YPR190C	RNA polymerase III subunit C82	physical	1	1	1	Affinity Capture-MS
MID1	YNL291C	Stretch-activated Ca2+-permeable cation channel	physical	1	1	1	Affinity Capture-MS
NOT5	YPR072W	Component of the CCR4-NOT core complex, involved in mRNA decapping	genetic	1	1	1	Synthetic Growth Defect
ASF1	YJL115W	Nucleosome assembly factor	physical	1	1	1	Affinity Capture-MS
MPT5	YGL178W	mRNA-binding protein of the PUF family	physical	1	1	1	Affinity Capture-RNA
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	genetic	1	1	1	Synthetic Growth Defect
HHT2	YNL031C	Histone H3	physical	1	1	1	Affinity Capture-Western
TDH3	YGR192C	Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3	physical	1	1	1	Affinity Capture-MS
CDC39	YCR093W	Subunit of the CCR4-NOT1 core complex	physical	1	1	1	Affinity Capture-RNA
CAF20	YOR276W	Phosphoprotein of the mRNA cap-binding complex	physical	1	1	1	Affinity Capture-RNA
APJ1	YNL077W	Hsp40 chaperone with a role in SUMO-mediated protein degradation	physical	1	1	1	Affinity Capture-MS
SPT16	YGL207W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p)	physical	1	1	1	Affinity Capture-MS
MOT2	YER068W	Ubiquitin-protein ligase subunit of the CCR4-NOT complex	genetic	1	1	1	Synthetic Growth Defect
SRB5	YGR104C	Subunit of the RNA polymerase II mediator complex	genetic	1	1	1	Synthetic Growth Defect
RPB9	YGL070C	RNA polymerase II subunit B12.6	genetic	1	1	1	Synthetic Lethality
SPT2	YER161C	Protein involved in negative regulation of transcription	genetic	1	1	1	Synthetic Rescue
FMT1	YBL013W	Methionyl-tRNA formyltransferase	genetic	1	1	1	Negative Genetic
ARF1	YDL192W	ADP-ribosylation factor	genetic	1	1	1	Negative Genetic
SNF11	YDR073W	Subunit of the SWI/SNF chromatin remodeling complex	genetic	1	1	1	Negative Genetic
IPK1	YDR315C	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase	genetic	1	1	1	Negative Genetic
MSN5	YDR335W	Karyopherin	genetic	1	1	1	Negative Genetic
DEG1	YFL001W	tRNA:pseudouridine synthase	genetic	1	1	1	Negative Genetic
ARO2	YGL148W	Bifunctional chorismate synthase and flavin reductase	genetic	1	1	1	Negative Genetic
LRP1	YHR081W	Nuclear exosome-associated nucleic acid binding protein	genetic	1	1	1	Negative Genetic
LSM1	YJL124C	Lsm (Like Sm) protein	genetic	1	1	1	Negative Genetic
IRC25	YLR021W	Component of a heterodimeric Poc4p-Irc25p chaperone	genetic	1	1	1	Negative Genetic
FDO1	YMR144W	Protein involved in directionality of mating type switching	genetic	1	1	1	Negative Genetic
ATG41	YPL250C	Protein of unknown function	genetic	1	1	1	Negative Genetic
NAM2	YLR382C	Mitochondrial leucyl-tRNA synthetase	genetic	1	1	1	Synthetic Lethality
LEA1	YPL213W	Component of U2 snRNP complex	genetic	1	1	1	Synthetic Lethality
VMA21	YGR105W	Integral membrane protein required for V-ATPase function	genetic	1	1	1	Synthetic Growth Defect
HDA2	YDR295C	Subunit of HDA1 histone deacetylase complex	genetic	1	1	1	Synthetic Rescue
RPN10	YHR200W	Proteasome polyubiquitin receptor	genetic	1	1	1	Synthetic Rescue
COG4	YPR105C	Essential component of the conserved oligomeric Golgi complex	genetic	1	1	1	Synthetic Rescue
VPS72	YDR485C	Htz1p-binding component of the SWR1 complex	genetic	1	1	1	Synthetic Rescue
RSC4	YKR008W	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Synthetic Lethality
RLM1	YPL089C	MADS-box transcription factor	genetic	1	1	1	Positive Genetic
FKH2	YNL068C	Forkhead family transcription factor	genetic	1	1	1	Positive Genetic
CBF1	YJR060W	Basic helix-loop-helix (bHLH) protein	genetic	1	1	1	Negative Genetic
GLN3	YER040W	Transcriptional activator in nitrogen catabolite repression system	genetic	1	1	1	Negative Genetic
KCS1	YDR017C	Inositol hexakisphosphate and inositol heptakisphosphate kinase	genetic	1	1	1	Negative Genetic
PPZ1	YML016C	Serine/threonine protein phosphatase Z, isoform of Ppz2p	genetic	1	1	1	Negative Genetic
LTP1	YPR073C	Protein phosphotyrosine phosphatase of unknown cellular role	genetic	1	1	1	Negative Genetic
RTG1	YOL067C	Transcription factor (bHLH) involved in interorganelle communication	genetic	1	1	1	Negative Genetic
RPH1	YER169W	JmjC domain-containing histone demethylase	genetic	1	1	1	Negative Genetic
LCB5	YLR260W	Minor sphingoid long-chain base kinase	genetic	1	1	1	Negative Genetic
CLN2	YPL256C	G1 cyclin involved in regulation of the cell cycle	genetic	1	1	1	Negative Genetic
PRR2	YDL214C	Serine/threonine protein kinase	genetic	1	1	1	Negative Genetic
SIP3	YNL257C	Putative sterol transfer protein	genetic	1	1	1	Negative Genetic
RPN4	YDL020C	Transcription factor that stimulates expression of proteasome genes	genetic	1	1	1	Negative Genetic
KDX1	YKL161C	Protein kinase	genetic	1	1	1	Negative Genetic
KAR4	YCL055W	Transcription factor required for response to pheromones	genetic	1	1	1	Negative Genetic
TYE7	YOR344C	Serine-rich protein that contains a bHLH DNA binding motif	genetic	1	1	1	Negative Genetic
CMK1	YFR014C	Calmodulin-dependent protein kinase	genetic	1	1	1	Negative Genetic
YAP3	YHL009C	Basic leucine zipper (bZIP) transcription factor	genetic	1	1	1	Negative Genetic
FAR10	YLR238W	Protein involved in recovery from arrest in response to pheromone	genetic	1	1	1	Negative Genetic
BCK1	YJL095W	MAPKKK acting in the protein kinase C signaling pathway	genetic	1	1	1	Negative Genetic
SUP35	YDR172W	Translation termination factor eRF3	genetic	1	1	1	Phenotypic Suppression
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	genetic	1	1	1	Synthetic Growth Defect
HTB1	YDR224C	Histone H2B	genetic	1	1	1	Synthetic Rescue
HMT1	YBR034C	Nuclear SAM-dependent mono- and asymmetric methyltransferase	genetic	1	1	1	Negative Genetic
NPL3	YDR432W	RNA-binding protein	genetic	1	1	1	Synthetic Growth Defect
SAD1	YFR005C	Conserved zinc-finger domain protein involved in pre-mRNA splicing	genetic	1	1	1	Negative Genetic
EXO70	YJL085W	Subunit of the exocyst complex	genetic	1	1	1	Negative Genetic
MAK11	YKL021C	Protein involved in an early step of 60S ribosomal subunit biogenesis	genetic	1	1	1	Negative Genetic
PRI2	YKL045W	Subunit of DNA primase	genetic	1	1	1	Negative Genetic
CSE4	YKL049C	Centromeric histone H3-like protein	genetic	1	1	1	Negative Genetic
ASK1	YKL052C	Essential subunit of the Dam1 complex (aka DASH complex)	genetic	1	1	1	Negative Genetic
SNU114	YKL173W	GTPase component of U5 snRNP involved in mRNA splicing via spliceosome	genetic	1	1	1	Negative Genetic
RPF2	YKR081C	Essential protein involved in rRNA maturation and ribosomal assembly	genetic	1	1	1	Negative Genetic
GSP1	YLR293C	Ran GTPase	genetic	1	1	1	Negative Genetic
RPL19B	YBL027W	Ribosomal 60S subunit protein L19B	genetic	1	1	1	Negative Genetic
SEA4	YBL104C	Subunit of SEACAT, a subcomplex of the SEA complex	genetic	1	1	1	Negative Genetic
SLM3	YDL033C	tRNA-specific 2-thiouridylase	genetic	1	1	1	Negative Genetic
MRPL1	YDR116C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Negative Genetic
ARO1	YDR127W	Pentafunctional arom protein	genetic	1	1	1	Negative Genetic
UBP6	YFR010W	Ubiquitin-specific protease	genetic	1	1	1	Negative Genetic
CBP4	YGR174C	Mitochondrial protein required for assembly of cytochrome bc1 complex	genetic	1	1	1	Negative Genetic
PBP1	YGR178C	Component of glucose deprivation induced stress granules	genetic	1	1	1	Negative Genetic
DPH1	YIL103W	Protein required for synthesis of diphthamide	genetic	1	1	1	Negative Genetic
AIM26	YKL037W	Protein of unknown function	genetic	1	1	1	Negative Genetic
HAP4	YKL109W	Transcription factor	genetic	1	1	1	Negative Genetic
LST4	YKL176C	Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p	genetic	1	1	1	Negative Genetic
SAC1	YKL212W	Phosphatidylinositol phosphate phosphatase	genetic	1	1	1	Negative Genetic
YDJ1	YNL064C	Type I HSP40 co-chaperone	genetic	1	1	1	Negative Genetic
ADH1	YOL086C	Alcohol dehydrogenase	genetic	1	1	1	Negative Genetic
CYT1	YOR065W	Cytochrome c1	genetic	1	1	1	Negative Genetic
DIA2	YOR080W	Origin-binding F-box protein	genetic	1	1	1	Negative Genetic
MFM1	YPL060W	Mitochondrial inner membrane magnesium transporter	genetic	1	1	1	Negative Genetic
PEX35	YGR168C	Regulator of peroxisome abundance	genetic	1	1	1	Synthetic Growth Defect
CYC8	YBR112C	General transcriptional co-repressor	genetic	1	1	1	Phenotypic Suppression
ADO1	YJR105W	Adenosine kinase	genetic	1	1	1	Phenotypic Suppression
AUR1	YKL004W	Phosphatidylinositol:ceramide phosphoinositol transferase	genetic	1	1	1	Negative Genetic