Standard name Systematic name Name description Description
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; negatively regulates Fpk1p kinase that stimulates phospholipid flippases Dnf1p and Dnf2p; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication
Visualize the interactome of GIN4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 46

CYCLoPs localization & abundance

WT1 WT2 WT3
Budneck 0.183 0.056 0.208
Budsite 0.127 0.111 0.104
Cell Periphery 0.087 NaN NaN
Cytoplasm 0.491 0.611 0.521
Nucleolus 0.130 0.056 0.125
Nucleus 0.059 NaN 0.062
SpindlePole 0.112 NaN NaN
ER NaN 0.056 NaN
Mito NaN 0.056 0.083
Peroxisome NaN 0.056 NaN
Vac/Vac Memb NaN 0.056 NaN
Bud NaN NaN 0.073

GFP localization & abundance

GFP localization GFP abundance
ambiguous, bud neck, cytoplasm, bud 736

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GIN4 0 0 2 1 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 12 3 11 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, PCA, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SHS1 YDL225W Component of the septin ring that is required for cytokinesis physical 6 3 5 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Affinity Capture-MS
SWI6 YLR182W Transcription cofactor genetic 6 3 5 Dosage Rescue, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 5 3 5 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Two-hybrid
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 5 2 5 Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 5 3 4 Phenotypic Enhancement, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 4 3 4 Phenotypic Enhancement, Synthetic Lethality, Phenotypic Suppression, Phenotypic Enhancement
CDC10 YCR002C Component of the septin ring, required for cytokinesis physical 4 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
CDC12 YHR107C Component of the septin ring that is required for cytokinesis physical 4 2 4 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 4 2 4 Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic
MIH1 YMR036C Protein tyrosine phosphatase genetic 4 2 4 Negative Genetic, Phenotypic Suppression, Negative Genetic, Negative Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 4 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BNI1 YNL271C Formin genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 4 2 3 Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 4 2 3 Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 3 3 3 Affinity Capture-Western, PCA, Biochemical Activity
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint genetic 3 3 3 Synthetic Rescue, Synthetic Lethality, Phenotypic Enhancement
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 3 3 3 Synthetic Lethality, Synthetic Growth Defect, Dosage Growth Defect
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 3 3 3 Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Lethality
CDC11 YJR076C Component of the septin ring that is required for cytokinesis physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 3 2 3 Negative Genetic, Dosage Growth Defect, Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
BEM1 YBR200W Protein containing SH3-domains genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RIM11 YMR139W Protein kinase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YGR273C YGR273C Putative protein of unknown function genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YKL075C YKL075C Putative protein of unknown function genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YMR187C YMR187C Putative protein of unknown function genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 3 3 2 Dosage Rescue, Synthetic Lethality, Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 3 3 2 Synthetic Lethality, Phenotypic Enhancement, Dosage Rescue
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 3 2 1 PCA, PCA, Reconstituted Complex
BNR1 YIL159W Formin physical 3 2 1 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
CDC42 YLR229C Small rho-like GTPase genetic 2 2 2 Phenotypic Enhancement, Dosage Rescue
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 2 Dosage Growth Defect, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 2 2 2 Dosage Growth Defect, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 2 2 2 Dosage Growth Defect, Negative Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 2 2 2 Negative Genetic, Dosage Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
CMD1 YBR109C Calmodulin genetic 2 2 2 Dosage Growth Defect, Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 2 2 2 Phenotypic Enhancement, Dosage Growth Defect
HSL1 YKL101W Nim1p-related protein kinase physical 2 2 2 Affinity Capture-MS, PCA
PFY1 YOR122C Profilin genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 2 2 2 Synthetic Lethality, Dosage Growth Defect
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
ELM1 YKL048C Serine/threonine protein kinase physical 2 2 2 Biochemical Activity, Two-hybrid
FPK1 YNR047W Ser/Thr protein kinase genetic 2 2 2 Dosage Growth Defect, Phenotypic Suppression
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 2 2 2 Positive Genetic, Phenotypic Enhancement
BUD4 YJR092W Anillin-like protein involved in bud-site selection genetic 2 2 2 Phenotypic Enhancement, Dosage Growth Defect
BNI5 YNL166C Linker protein responsible for recruitment of myosin to the bud neck physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 2 Negative Genetic, Negative Genetic
FYV4 YHR059W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 2 1 2 Two-hybrid, Two-hybrid
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) physical 2 1 2 Two-hybrid, Two-hybrid
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 2 1 2 PCA, PCA
YBR238C YBR238C Mitochondrial membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SUL1 YBR294W High affinity sulfate permease of the SulP anion transporter family genetic 2 1 2 Negative Genetic, Negative Genetic
THR4 YCR053W Threonine synthase genetic 2 1 2 Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 2 1 2 Negative Genetic, Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 2 1 2 Negative Genetic, Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 2 1 2 Negative Genetic, Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 2 1 2 Negative Genetic, Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
CHS3 YBR023C Chitin synthase III genetic 2 1 2 Negative Genetic, Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 2 1 2 Negative Genetic, Negative Genetic
REI1 YBR267W Cytoplasmic pre-60S factor genetic 2 2 1 Phenotypic Enhancement, Synthetic Lethality
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
PTC1 YDL006W Type 2C protein phosphatase (PP2C) physical 2 1 1 PCA, PCA
PDS5 YMR076C Cohesion maintenance factor physical 2 1 1 Two-hybrid, Two-hybrid
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
FMP32 YFL046W Regulator of mitochondrial proline metabolism physical 2 1 1 Two-hybrid, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
ZAP1 YJL056C Zinc-regulated transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
INO2 YDR123C Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI6 YLR182W Transcription cofactor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MBP1 YDL056W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring regulation 1 1 1 protein kinase assay evidence
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Dosage Growth Defect
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing physical 1 1 1 Affinity Capture-MS
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Dosage Growth Defect
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B physical 1 1 1 Reconstituted Complex
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Dosage Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Reconstituted Complex
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Dosage Growth Defect
SAW1 YAL027W 5'- and 3'-flap DNA binding protein physical 1 1 1 Affinity Capture-MS
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-Western
YLL054C YLL054C Putative protein of unknown function with similarity to Pip2p physical 1 1 1 Affinity Capture-Western
NIS1 YNL078W Protein involved in axial bud site selection physical 1 1 1 Two-hybrid
REI1 YBR267W Cytoplasmic pre-60S factor physical 1 1 1 Reconstituted Complex
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Affinity Capture-Western
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Biochemical Activity
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Affinity Capture-MS
VPS75 YNL246W NAP family histone chaperone physical 1 1 1 Affinity Capture-MS
PRI1 YIR008C Subunit of DNA primase physical 1 1 1 Affinity Capture-MS
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) physical 1 1 1 Affinity Capture-MS
SEG1 YMR086W Component of eisosome required for proper eisosome assembly physical 1 1 1 Biochemical Activity
YLR345W YLR345W Similar to 6-phosphofructo-2-kinase enzymes physical 1 1 1 Biochemical Activity
MBR1 YKL093W Protein involved in mitochondrial functions and stress response physical 1 1 1 Biochemical Activity
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Affinity Capture-MS
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Growth Defect
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase physical 1 1 1 Reconstituted Complex
GSY2 YLR258W Glycogen synthase physical 1 1 1 Reconstituted Complex
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism physical 1 1 1 Reconstituted Complex
MAK10 YEL053C Non-catalytic subunit of the NatC N-terminal acetyltransferase physical 1 1 1 Reconstituted Complex
MDM36 YPR083W Mitochondrial protein physical 1 1 1 Reconstituted Complex
MPD1 YOR288C Member of the protein disulfide isomerase (PDI) family physical 1 1 1 Reconstituted Complex
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Reconstituted Complex
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis physical 1 1 1 Reconstituted Complex
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Reconstituted Complex
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit physical 1 1 1 Reconstituted Complex
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Reconstituted Complex
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Reconstituted Complex
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p physical 1 1 1 Reconstituted Complex
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis physical 1 1 1 Reconstituted Complex
YGR017W YGR017W Putative protein of unknown function physical 1 1 1 Reconstituted Complex
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p physical 1 1 1 Two-hybrid
YLR031W YLR031W Putative protein of unknown function physical 1 1 1 Two-hybrid
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family physical 1 1 1 Two-hybrid
NCA2 YPR155C Protein that regulates expression of Fo-F1 ATP synthase subunits physical 1 1 1 Two-hybrid
NDL1 YLR254C Homolog of nuclear distribution factor NudE physical 1 1 1 Two-hybrid
IMH1 YLR309C Protein involved in vesicular transport physical 1 1 1 Two-hybrid
MGE1 YOR232W Mitochondrial matrix cochaperone physical 1 1 1 Two-hybrid
NIP100 YPL174C Large subunit of the dynactin complex physical 1 1 1 Two-hybrid
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Dosage Growth Defect
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOB1 YIL106W Component of the mitotic exit network physical 1 1 1 Proximity Label-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Proximity Label-MS
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 1 1 1 Phenotypic Enhancement
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Synthetic Lethality
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Positive Genetic
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
PLC1 YPL268W Phospholipase C genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Synthetic Rescue
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
YOL131W YOL131W Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Dosage Growth Defect
SAP1 YER047C Putative ATPase of the AAA family genetic 1 1 1 Dosage Growth Defect
TDA11 YHR159W Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
SLK19 YOR195W Kinetochore-associated protein genetic 1 1 1 Dosage Growth Defect
ISR1 YPR106W Predicted protein kinase genetic 1 1 1 Dosage Growth Defect
PXP2 YJR111C Peroxisomal matrix protein with naturally active promoter genetic 1 1 1 Dosage Growth Defect
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 1 1 1 Dosage Growth Defect
MLF3 YNL074C Serine-rich protein of unknown function genetic 1 1 1 Dosage Growth Defect
KEL1 YHR158C Protein required for proper cell fusion and cell morphology genetic 1 1 1 Dosage Growth Defect
YPR015C YPR015C Putative zinc finger transcription factor genetic 1 1 1 Dosage Growth Defect
PIL1 YGR086C Eisosome core component genetic 1 1 1 Dosage Growth Defect
PRM2 YIL037C Pheromone-regulated protein genetic 1 1 1 Dosage Growth Defect
PAR32 YDL173W Low complexity protein genetic 1 1 1 Dosage Growth Defect
TRX3 YCR083W Mitochondrial thioredoxin genetic 1 1 1 Dosage Growth Defect
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
MLC1 YGL106W Essential light chain for Myo1p genetic 1 1 1 Dosage Growth Defect
SYH1 YPL105C Protein of unknown function that influences nuclear pore distribution genetic 1 1 1 Dosage Growth Defect
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 1 1 1 Dosage Growth Defect
TOS7 YOL019W Protein involved in secretion and cell wall organization genetic 1 1 1 Dosage Growth Defect
YER137C-A YER137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol genetic 1 1 1 Dosage Growth Defect
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Dosage Growth Defect
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Dosage Growth Defect
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Dosage Growth Defect
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Dosage Growth Defect
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane genetic 1 1 1 Dosage Growth Defect
MDJ1 YFL016C Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity genetic 1 1 1 Dosage Growth Defect
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions genetic 1 1 1 Dosage Growth Defect
MSB3 YNL293W Rab GTPase-activating protein genetic 1 1 1 Dosage Growth Defect
GLG1 YKR058W Glycogenin glucosyltransferase genetic 1 1 1 Dosage Growth Defect
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Dosage Growth Defect
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Dosage Growth Defect
NSG2 YNL156C Protein involved in regulation of sterol biosynthesis genetic 1 1 1 Dosage Growth Defect
YIL055C YIL055C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Dosage Growth Defect
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Dosage Growth Defect
NOP8 YOL144W Nucleolar protein required for 60S ribosomal subunit biogenesis genetic 1 1 1 Dosage Growth Defect
MCM6 YGL201C Protein involved in DNA replication genetic 1 1 1 Dosage Growth Defect
SGN1 YIR001C Cytoplasmic RNA-binding protein genetic 1 1 1 Dosage Growth Defect
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 1 1 1 Dosage Growth Defect
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Dosage Growth Defect
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Dosage Growth Defect
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 1 1 1 Dosage Growth Defect
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 1 1 1 Dosage Growth Defect
WTM2 YOR229W Transcriptional modulator genetic 1 1 1 Dosage Growth Defect
YNL108C YNL108C Protein phosphatase genetic 1 1 1 Dosage Growth Defect
SKG3 YLR187W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
PFK27 YOL136C 6-phosphofructo-2-kinase genetic 1 1 1 Dosage Growth Defect
SPS22 YCL048W Protein of unknown function genetic 1 1 1 Dosage Growth Defect
RSA1 YPL193W Protein involved in the assembly of 60S ribosomal subunits genetic 1 1 1 Dosage Growth Defect
YER085C YER085C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Dosage Growth Defect
MET4 YNL103W Leucine-zipper transcriptional activator genetic 1 1 1 Dosage Growth Defect
YPL278C YPL278C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Dosage Growth Defect
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Dosage Growth Defect
RRT5 YFR032C Putative protein of unknown function genetic 1 1 1 Dosage Growth Defect
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Dosage Growth Defect
TAD1 YGL243W tRNA-specific adenosine deaminase genetic 1 1 1 Dosage Growth Defect
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Dosage Growth Defect
ISD11 YER048W-A Cysteine desulfurase (Nfs1p) activator genetic 1 1 1 Dosage Growth Defect
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 1 1 1 Dosage Growth Defect
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Dosage Growth Defect
ZRG8 YER033C Protein of unknown function genetic 1 1 1 Dosage Growth Defect
YHP1 YDR451C Homeobox transcriptional repressor genetic 1 1 1 Dosage Growth Defect
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 1 1 1 Dosage Growth Defect
SKS1 YPL026C Putative serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Dosage Growth Defect
WHI4 YDL224C Putative RNA binding protein genetic 1 1 1 Dosage Growth Defect
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Dosage Growth Defect
POG1 YIL122W DNA-binding transcriptional activator genetic 1 1 1 Dosage Growth Defect
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Dosage Growth Defect
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
MAS2 YHR024C Alpha subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
MRPS17 YMR188C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
KIN82 YCR091W Putative serine/threonine protein kinase genetic 1 1 1 Phenotypic Suppression
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Reconstituted Complex
AVT4 YNL101W Vacuolar transporter genetic 1 1 1 Dosage Growth Defect
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
CMS1 YLR003C Putative subunit of the 90S preribosome processome complex physical 1 1 1 Reconstituted Complex
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes physical 1 1 1 Reconstituted Complex
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
FKH1 YIL131C Forkhead family transcription factor genetic 1 1 1 Dosage Growth Defect
FDO1 YMR144W Protein involved in directionality of mating type switching genetic 1 1 1 Dosage Growth Defect
CAF120 YNL278W Part of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Dosage Growth Defect
DMA1 YHR115C Ubiquitin-protein ligase (E3) genetic 1 1 1 Synthetic Lethality
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Dosage Growth Defect
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Dosage Rescue
FPK1 YNR047W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Dosage Growth Defect
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Phenotypic Enhancement
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Dosage Growth Defect
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Dosage Growth Defect
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Dosage Growth Defect
BIT61 YJL058C Subunit of TORC2 membrane-associated complex genetic 1 1 1 Dosage Growth Defect
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
ACF4 YJR083C Protein of unknown function physical 1 1 1 Affinity Capture-Western
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
BNI5 YNL166C Linker protein responsible for recruitment of myosin to the bud neck genetic 1 1 1 Dosage Growth Defect
ECO1 YFR027W Acetyltransferase required for sister chromatid cohesion physical 1 1 1 Affinity Capture-Western
BUD8 YLR353W Protein involved in bud-site selection genetic 1 1 1 Dosage Growth Defect
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Two-hybrid
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Dosage Growth Defect
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Negative Genetic
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Dosage Growth Defect
FUS1 YCL027W Membrane protein localized to the shmoo tip genetic 1 1 1 Dosage Growth Defect
CLB3 YDL155W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
AIM44 YPL158C Regulator of Cdc42p and Rho1p physical 1 1 1 Two-hybrid
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Negative Genetic
ANB1 YJR047C Translation elongation factor eIF-5A physical 1 1 1 Reconstituted Complex
ARV1 YLR242C Cortical ER protein physical 1 1 1 Biochemical Activity
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Negative Genetic
DOT5 YIL010W Nuclear thiol peroxidase physical 1 1 1 Reconstituted Complex
ECM13 YBL043W Non-essential protein of unknown function genetic 1 1 1 Dosage Growth Defect
DAN1 YJR150C Cell wall mannoprotein genetic 1 1 1 Dosage Growth Defect