| NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
physical |
20 |
5 |
13 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure, Affinity Capture-MS |
| NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
16 |
4 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
physical |
15 |
4 |
11 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
15 |
4 |
10 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
13 |
4 |
10 |
Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
physical |
13 |
5 |
9 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
physical |
6 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
6 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex |
| NUP157 |
YER105C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
6 |
2 |
3 |
Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
5 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
5 |
3 |
5 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic, Synthetic Lethality |
| NUP49 |
YGL172W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
5 |
2 |
5 |
FRET, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
4 |
3 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Phenotypic Suppression |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Rescue, Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| NIC96 |
YFR002W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Rescue |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NUP82 |
YJL061W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
3 |
1 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
3 |
2 |
2 |
Negative Genetic, Dosage Lethality, Dosage Lethality |
| ATG8 |
YBL078C |
Ub-like protein |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
2 |
2 |
Synthetic Haploinsufficiency, Positive Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
| NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
| RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
| RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Phenotypic Enhancement |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| POM152 |
YMR129W |
Glycoprotein subunit of transmembrane ring of nuclear pore complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NDC1 |
YML031W |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| NUP42 |
YDR192C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HEH2 |
YDR458C |
Inner nuclear membrane (INM) protein |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM22 |
YJR135C |
Outer kinetochore protein and component of the Ctf3 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HHF1 |
YBR009C |
Histone H4 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSM3 |
YBR272C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IOC3 |
YFR013W |
Subunit of the Isw1a complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH6 |
YDR097C |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
physical |
1 |
1 |
1 |
Two-hybrid |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Co-purification |
| PDS1 |
YDR113C |
Securin |
physical |
1 |
1 |
1 |
Two-hybrid |
| SAC3 |
YDR159W |
mRNA export factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP17 |
YDR412W |
5' exoribonuclease required for 5' end processing of pre-60S rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| UBI4 |
YLL039C |
Ubiquitin |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD24 |
YER173W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP3 |
YLR234W |
DNA Topoisomerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD17 |
YOR368W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIF1 |
YBR275C |
Protein involved in control of DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP2 |
YOR124C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC13 |
YDR092W |
E2 ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAS2 |
YMR127C |
Histone acetyltransferase (HAT) catalytic subunit of the SAS complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIZ1 |
YDR409W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAC2 |
YER007W |
Microtubule effector required for tubulin heterodimer formation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSO2 |
YMR137C |
Nuclease required for DNA single- and double-strand break repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSY4 |
YBL046W |
Regulatory subunit of protein phosphatase PP4 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO13 |
YDL236W |
Conserved phosphatase acting as a metabolite repair enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POM33 |
YLL023C |
Transmembrane nucleoporin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSF2 |
YJL072C |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC10 |
YBR265W |
3-ketosphinganine reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAM35 |
YHR083W |
Component of the sorting and assembly machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDD3 |
YOL098C |
Putative metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ULS1 |
YOR191W |
Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPO4 |
YOR273C |
Polyamine transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX25 |
YPL112C |
Peripheral peroxisomal membrane peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD7 |
YJR052W |
Nucleotide excision repair (NER) protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| FAR1 |
YJL157C |
CDK inhibitor and nuclear anchor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DDC1 |
YPL194W |
DNA damage checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
PCA |
| GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP2 |
YLR335W |
Nucleoporin involved in nucleocytoplasmic transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHZ1 |
YER030W |
Histone chaperone for Htz1p/H2A-H2B dimer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC43 |
YGL155W |
Beta subunit of geranylgeranyltransferase type I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAR4 |
YCL055W |
Transcription factor required for response to pheromones |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSN5 |
YDR335W |
Karyopherin |
physical |
1 |
1 |
1 |
FRET |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOP1 |
YIL072W |
Meiosis-specific protein required for chromosome synapsis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IOC2 |
YLR095C |
Subunit of the Isw1b complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTR2 |
YKL186C |
mRNA transport regulator |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MPS2 |
YGL075C |
Essential membrane protein localized at nuclear envelope and SPBs |
physical |
1 |
1 |
1 |
Two-hybrid |
| CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GNT1 |
YOR320C |
N-acetylglucosaminyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATC1 |
YDR184C |
Nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENV11 |
YGR071C |
Protein proposed to be involved in vacuolar functions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEI5 |
YPL121C |
Meiosis-specific protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
physical |
1 |
1 |
1 |
PCA |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB4 |
YLR210W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LNP1 |
YHR192W |
Lunapark family member involved in ER network formation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |