| PAB1 |
YER165W |
Poly(A) binding protein |
physical |
23 |
5 |
17 |
Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Co-purification |
| CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
22 |
6 |
17 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Far Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Co-purification |
| TIF1 |
YKR059W |
Translation initiation factor eIF4A |
physical |
15 |
4 |
11 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
physical |
13 |
4 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
9 |
4 |
6 |
Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-fractionation, Reconstituted Complex |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
7 |
4 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-RNA, Reconstituted Complex, Affinity Capture-Western |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
5 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
4 |
4 |
3 |
Synthetic Lethality, Dosage Rescue, Dosage Growth Defect, Phenotypic Suppression |
| CDC33 |
YOL139C |
Translation initiation factor eIF4E |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS |
| SUI1 |
YNL244C |
Translation initiation factor eIF1 |
physical |
4 |
2 |
3 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
4 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NPL3 |
YDR432W |
RNA-binding protein |
physical |
3 |
3 |
3 |
Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western |
| PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
physical |
3 |
3 |
3 |
Affinity Capture-MS, Two-hybrid, Reconstituted Complex |
| TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Synthetic Rescue |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
| SCD6 |
YPR129W |
Repressor of translation initiation |
physical |
3 |
2 |
3 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RBG1 |
YAL036C |
Member of the DRG family of GTP-binding proteins |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
genetic |
3 |
3 |
2 |
Synthetic Rescue, Dosage Rescue, Dosage Lethality |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-Western |
| LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
| TIF3 |
YPR163C |
Translation initiation factor eIF-4B |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| KAP123 |
YER110C |
Karyopherin beta |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PUS7 |
YOR243C |
Pseudouridine synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ZUO1 |
YGR285C |
Ribosome-associated chaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TIF5 |
YPR041W |
Translation initiation factor eIF5 |
physical |
2 |
1 |
2 |
Reconstituted Complex, Reconstituted Complex |
| TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LHP1 |
YDL051W |
RNA binding protein required for maturation of tRNA and U6 snRNA |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HHF2 |
YNL030W |
Histone H4 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MRP7 |
YNL005C |
Mitochondrial ribosomal protein of the large subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
regulation |
2 |
2 |
1 |
protein kinase assay evidence, qualitative western immunoblotting evidence |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-RNA |
| SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
| RTC3 |
YHR087W |
Protein of unknown function involved in RNA metabolism |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSM23 |
YGL129C |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIX7 |
YLL034C |
Putative ATPase of the AAA family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMB1 |
YER029C |
Core Sm protein Sm B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GAR1 |
YHR089C |
Protein component of the H/ACA snoRNP pseudouridylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOP1 |
YOL006C |
Topoisomerase I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UTP7 |
YER082C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TSR1 |
YDL060W |
Protein required for processing of 20S pre-rRNA in the cytoplasm |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM40 |
YMR203W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TPT1 |
YOL102C |
tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TUB1 |
YML085C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TUB3 |
YML124C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBL005W-A |
YBL005W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBL100W-B |
YBL100W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TYS1 |
YGR185C |
Cytoplasmic tyrosyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| URA3 |
YEL021W |
Orotidine-5'-phosphate (OMP) decarboxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| URA6 |
YKL024C |
Uridylate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UTP15 |
YMR093W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YBL113C |
YBL113C |
Helicase-like protein encoded within the telomeric Y' element |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDL086W |
YDL086W |
Putative carboxymethylenebutenolidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDL124W |
YDL124W |
NADPH-dependent alpha-keto amide reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR391C |
YDR391C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHB1 |
YGR234W |
Nitric oxide oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIL161W |
YIL161W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YKL033W-A |
YKL033W-A |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPL245W |
YPL245W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YVH1 |
YIR026C |
Dual specificity protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| URB1 |
YKL014C |
Protein required for the normal accumulation of 25S and 5.8S rRNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP43 |
YCR035C |
Exosome non-catalytic core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MUD1 |
YBR119W |
U1 snRNP A protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRE8 |
YML092C |
Alpha 2 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ADE13 |
YLR359W |
Adenylosuccinate lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CAP1 |
YKL007W |
Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCL1 |
YPR025C |
Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CYS4 |
YGR155W |
Cystathionine beta-synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FAP7 |
YDL166C |
Essential NTPase required for small ribosome subunit synthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAS1 |
YLR163C |
Beta subunit of the mitochondrial processing protease (MPP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRP1 |
YDR347W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRPS5 |
YBR251W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LYS12 |
YIL094C |
Homo-isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| HSP42 |
YDR171W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBP2 |
YBR233W |
RNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB6 |
YML117W |
Putative RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMP4 |
YNL075W |
Component of the SSU processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOC4 |
YPR144C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHE2 |
YKL130C |
RNA-binding protein that binds specific mRNAs and interacts with She3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPE3 |
YPR069C |
Spermidine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNU71 |
YGR013W |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
1 |
1 |
1 |
Co-purification |
| CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSZ1 |
YHR064C |
Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MDH1 |
YKL085W |
Mitochondrial malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNR2 |
YJL026W |
Ribonucleotide-diphosphate reductase (RNR), small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMD5 |
YJR132W |
Karyopherin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC53 |
YFL045C |
Phosphomannomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRS3 |
YHL011C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARG4 |
YHR018C |
Argininosuccinate lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBK1 |
YNL161W |
Serine/threonine protein kinase of the the RAM signaling network |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DLD3 |
YEL071W |
2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DMA1 |
YHR115C |
Ubiquitin-protein ligase (E3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNQ1 |
YCL028W |
[PIN(+)] prion |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAG2 |
YLR427W |
Cytoplasmic protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EMI2 |
YDR516C |
Hexokinase expressed during growth with low glucose levels |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAG1 |
YER142C |
3-methyl-adenine DNA glycosylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPB11 |
YJL090C |
DNA replication initiation protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSC1 |
YOR142W |
Alpha subunit of succinyl-CoA ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP13 |
YNL175C |
Nucleolar protein found in preribosomal complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RMT2 |
YDR465C |
Arginine N5 methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APA1 |
YCL050C |
AP4A phosphorylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MCM4 |
YPR019W |
Essential helicase component of heterohexameric MCM2-7 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BIO3 |
YNR058W |
7,8-diamino-pelargonic acid aminotransferase (DAPA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CPA1 |
YOR303W |
Small subunit of carbamoyl phosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARO9 |
YHR137W |
Aromatic aminotransferase II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRS1 |
YKL181W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS26A |
YGL189C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG34 |
YOL083W |
Receptor protein involved in selective autophagy during starvation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IBD2 |
YNL164C |
Component of the BUB2-dependent spindle checkpoint pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MTH1 |
YDR277C |
Negative regulator of the glucose-sensing signal transduction pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MYO5 |
YMR109W |
One of two type I myosin motors |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| NAM9 |
YNL137C |
Mitochondrial ribosomal component of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSA3 |
YBL075C |
ATPase involved in protein folding and the response to stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MTF2 |
YDL044C |
Mitochondrial protein that interacts with mitochondrial RNA polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARK1 |
YNL020C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAM2 |
YDR502C |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRI1 |
YIR008C |
Subunit of DNA primase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSL5 |
YLR116W |
Component of commitment complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF3 |
YPR163C |
Translation initiation factor eIF-4B |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ETT1 |
YOR051C |
Nuclear protein that inhibits replication of Brome mosaic virus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DYS1 |
YHR068W |
Deoxyhypusine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LEU1 |
YGL009C |
Isopropylmalate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LYS21 |
YDL131W |
Homocitrate synthase isozyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MEU1 |
YLR017W |
Methylthioadenosine phosphorylase (MTAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARO8 |
YGL202W |
Aromatic aminotransferase I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCC1 |
YLR220W |
Vacuolar Fe2+/Mn2+ transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP26 |
YBR072W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAP1 |
YLR244C |
Methionine aminopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRPL11 |
YDL202W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HXK1 |
YFR053C |
Hexokinase isoenzyme 1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FRD1 |
YEL047C |
Soluble fumarate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LAP3 |
YNL239W |
Cysteine aminopeptidase with homocysteine-thiolactonase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSA3 |
YLR221C |
Protein with a likely role in ribosomal maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GUA1 |
YMR217W |
GMP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEM1 |
YDR232W |
5-aminolevulinate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SSF2 |
YDR312W |
Protein required for ribosomal large subunit maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LOA1 |
YPR139C |
Lysophosphatidic acid acyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OTU2 |
YHL013C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ASP1 |
YDR321W |
Cytosolic L-asparaginase, involved in asparagine catabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIP1 |
YEL024W |
Ubiquinol-cytochrome-c reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SDD4 |
YPR022C |
Putative transcription factor, as suggested by computational analysis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTC1 |
YOL138C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAE1 |
YBR261C |
AdoMet-dependent proline methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CTT1 |
YGR088W |
Cytosolic catalase T |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCG1 |
YER163C |
Gamma-glutamyl cyclotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MET5 |
YJR137C |
Sulfite reductase beta subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MIC12 |
YBR262C |
Component of the MICOS complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FSH3 |
YOR280C |
Putative serine hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CPR8 |
YNR028W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOD5 |
YOR274W |
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALD3 |
YMR169C |
Cytoplasmic aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMP1 |
YCR024C-A |
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BIO4 |
YNR057C |
Dethiobiotin synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BCD1 |
YHR040W |
Essential protein required for the accumulation of box C/D snoRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCP1 |
YOR367W |
Component of yeast cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ODC2 |
YOR222W |
Mitochondrial inner membrane transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIT1 |
YMR283C |
Initiator methionine 2'-O-ribosyl phosphate transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIT1 |
YMR283C |
Initiator methionine 2'-O-ribosyl phosphate transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYT1 |
YPR095C |
Guanine nucleotide exchange factor (GEF) for Arf proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
