GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
genetic |
14 |
4 |
14 |
Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Synthetic Rescue, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
physical |
11 |
5 |
9 |
Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, PCA, PCA, Affinity Capture-Western, Affinity Capture-Western |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
5 |
4 |
5 |
Synthetic Rescue, Positive Genetic, Phenotypic Suppression, Synthetic Rescue, Dosage Rescue |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
physical |
5 |
1 |
4 |
Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
AZF1 |
YOR113W |
Zinc-finger transcription factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
regulation |
3 |
3 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-qPCR evidence, northern blot evidence |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
3 |
3 |
1 |
Affinity Capture-Western, Two-hybrid, Biochemical Activity |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
2 |
2 |
2 |
Reconstituted Complex, Two-hybrid |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Enhancement |
PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Suppression |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HAA1 |
YPR008W |
Transcriptional activator involved in adaptation to weak acid stress |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GZF3 |
YJL110C |
GATA zinc finger protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MSN1 |
YOL116W |
Transcriptional activator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YAK1 |
YJL141C |
Serine-threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
physical |
2 |
2 |
1 |
Co-localization, Affinity Capture-Western |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Phenotypic Enhancement |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
RNR1 |
YER070W |
Major isoform of large subunit of ribonucleotide-diphosphate reductase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
MET7 |
YOR241W |
Folylpolyglutamate synthetase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BPT1 |
YLL015W |
ABC type transmembrane transporter of MRP/CFTR family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAL5 |
YJR152W |
Allantoate permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAL2 |
YIR029W |
Allantoicase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAL1 |
YIR027C |
Allantoinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAL4 |
YIR028W |
Allantoin permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAR1 |
YPL111W |
Arginase, catabolizes arginine to ornithine and urea |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ARG4 |
YHR018C |
Argininosuccinate lyase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ARG1 |
YOL058W |
Arginosuccinate synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ASN1 |
YPR145W |
Asparagine synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PDR11 |
YIL013C |
ATP-binding cassette (ABC) transporter |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HMS1 |
YOR032C |
bHLH protein with similarity to myc-family transcription factors |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ASP3-1 |
YLR155C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ASP3-2 |
YLR157C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ASP3-4 |
YLR160C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DAN4 |
YJR151C |
Cell wall mannoprotein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LAA2 |
YBL010C |
Clathrin adaptor (adaptin) accessory protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ARP10 |
YDR106W |
Component of the dynactin complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPA2 |
YLL021W |
Component of the polarisome |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NOP16 |
YER002W |
Constituent of 66S pre-ribosomal particles |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PHO81 |
YGR233C |
Cyclin-dependent kinase (CDK) inhibitor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GRX2 |
YDR513W |
Cytoplasmic glutaredoxin |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
URA1 |
YKL216W |
Dihydroorotate dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
DUS1 |
YML080W |
Dihydrouridine synthase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ECT1 |
YGR007W |
Ethanolamine-phosphate cytidylyltransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FET3 |
YMR058W |
Ferro-O2-oxidoreductase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HXT11 |
YOL156W |
Hexose transporter |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MET2 |
YNL277W |
L-homoserine-O-acetyltransferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAR2 |
YLR438W |
L-ornithine transaminase (OTAse) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RNR1 |
YER070W |
Major isoform of large subunit of ribonucleotide-diphosphate reductase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
DAL7 |
YIR031C |
Malate synthase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RNR3 |
YIL066C |
Minor isoform of large subunit of ribonucleotide-diphosphate reductase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
regulation |
1 |
1 |
1 |
northern blot evidence |
AAC1 |
YMR056C |
Mitochondrial inner membrane ADP/ATP translocator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MPM1 |
YJL066C |
Mitochondrial intermembrane space protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MIX14 |
YDR031W |
Mitochondrial intermembrane space protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ARG7 |
YMR062C |
Mitochondrial ornithine acetyltransferase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MLO1 |
YMR252C |
Mitochondrial protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MRPL38 |
YKL170W |
Mitochondrial ribosomal protein of the large subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RSM19 |
YNR037C |
Mitochondrial ribosomal protein of the small subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HIS4 |
YCL030C |
Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ITR1 |
YDR497C |
Myo-inositol transporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GDH2 |
YDL215C |
NAD(+)-dependent glutamate dehydrogenase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YHB1 |
YGR234W |
Nitric oxide oxidoreductase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NOC4 |
YPR144C |
Nucleolar protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GPA2 |
YER020W |
Nucleotide binding alpha subunit of the heterotrimeric G protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CPR4 |
YCR069W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
INP2 |
YMR163C |
Peroxisome-specific receptor important for peroxisome inheritance |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
VAC17 |
YCL063W |
Phosphoprotein involved in vacuole inheritance |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AGP2 |
YBR132C |
Plasma membrane regulator of polyamine and carnitine transport |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DUR3 |
YHL016C |
Plasma membrane transporter for both urea and polyamines |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RED1 |
YLR263W |
Protein component of the synaptonemal complex axial elements |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PBA1 |
YLR199C |
Protein involved in 20S proteasome assembly |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAD28 |
YDR030C |
Protein involved in DNA repair |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MAM3 |
YOL060C |
Protein involved in magnesium homeostasis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BDF2 |
YDL070W |
Protein involved in transcription initiation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DCG1 |
YIR030C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YDL211C |
YDL211C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YHI9 |
YHR029C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GEP5 |
YLR091W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ABM1 |
YJR108W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NIF3 |
YGL221C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YMR316C-A |
YMR316C-A |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MCH4 |
YOL119C |
Protein with similarity to mammalian monocarboxylate permeases |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAR064W |
YAR064W |
Pseudogenic fragment with similarity to flocculins |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PBR1 |
YNL181W |
Putative oxidoreductase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YEL076C-A |
YEL076C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YHL015W-A |
YHL015W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YKR045C |
YKR045C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YCR043C |
YCR043C |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YJR151W-A |
YJR151W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YKL096C-B |
YKL096C-B |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YGL007C-A |
YGL007C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YGL006W-A |
YGL006W-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RNR2 |
YJL026W |
Ribonucleotide-diphosphate reductase (RNR), small subunit |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HUG1 |
YML058W-A |
Ribonucleotide reductase inhibitor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL33B |
YOR234C |
Ribosomal 60S subunit protein L33B |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HMLALPHA1 |
YCL066W |
Silenced copy of ALPHA1 at HML |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RFA3 |
YJL173C |
Subunit of heterotrimeric Replication Protein A (RPA) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RRI2 |
YOL117W |
Subunit of the COP9 signalosome (CSN) complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TSA1 |
YML028W |
Thioredoxin peroxidase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RDL1 |
YOR285W |
Thiosulfate sulfurtransferase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
NQM1 |
YGR043C |
Transaldolase of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
WTM1 |
YOR230W |
Transcriptional modulator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MCM1 |
YMR043W |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RPI1 |
YIL119C |
Transcription factor, allelic differences between S288C and Sigma1278b |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HSH155 |
YMR288W |
U2-snRNP associated splicing factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UBX7 |
YBR273C |
UBX (ubiquitin regulatory X) domain-containing protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
PMC1 |
YGL006W |
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CPS1 |
YJL172W |
Vacuolar carboxypeptidase S |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SNC1 |
YAL030W |
Vesicle membrane receptor protein (v-SNARE) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XYL2 |
YLR070C |
Xylitol dehydrogenase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUS1 |
YMR240C |
Protein required for assembly of U2 snRNP into the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPB3 |
YBR278W |
Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECM5 |
YMR176W |
Subunit of the Snt2C complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DPB4 |
YDR121W |
Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Positive Genetic |
GDT1 |
YBR187W |
Calcium and manganese transporter with higher affinity for Ca2+ |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCF1 |
YDR339C |
PINc domain endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GDH1 |
YOR375C |
NADP(+)-dependent glutamate dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHA4 |
YLR098C |
DNA binding transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Two-hybrid |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
1 |
1 |
1 |
Two-hybrid |
MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Co-localization |
RAD53 |
YPL153C |
DNA damage response kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RIM11 |
YMR139W |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SOK1 |
YDR006C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ULS1 |
YOR191W |
Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
WTM2 |
YOR229W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOS8 |
YGL096W |
Homeodomain-containing protein and putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPS18 |
YNL204C |
Protein of unknown function, contains a putative zinc-binding domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
OTU1 |
YFL044C |
Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RME1 |
YGR044C |
Zinc finger protein involved in control of meiosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPH1 |
YER169W |
JmjC domain-containing histone demethylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPR1 |
YNL183C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PLM2 |
YDR501W |
Putative transcription factor, contains Forkhead Associated domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD17 |
YOR368W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Synthetic Haploinsufficiency |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
genetic |
1 |
1 |
1 |
Synthetic Haploinsufficiency |
STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSE1 |
YML049C |
Protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEX2 |
YJL210W |
RING-finger peroxin and E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEX13 |
YLR191W |
Peroxisomal importomer complex component |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM2 |
YBL026W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPP381 |
YBR152W |
mRNA splicing factor, component of U4/U6.U5 tri-snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP6 |
YDR449C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUK1 |
YDR454C |
Guanylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP31 |
YGR091W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP3 |
YHR065C |
Protein involved in rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP8 |
YOL144W |
Nucleolar protein required for 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMP3 |
YOR149C |
Alpha 1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HMT1 |
YBR034C |
Nuclear SAM-dependent mono- and asymmetric methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL41B |
YDL133C-A |
Ribosomal 60S subunit protein L41B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWP82 |
YFL049W |
Member of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL036W |
YGL036W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM21 |
YGR033C |
Nonessential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSV2 |
YGR223C |
Phosphatidylinositol 3,5-bisphosphate-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR033W |
YHR033W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPM1 |
YIL110W |
AdoMet-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFH5 |
YJL145W |
Unusual phosphatidylinositol transfer protein (PITP) that binds heme |
genetic |
1 |
1 |
1 |
Negative Genetic |
IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
genetic |
1 |
1 |
1 |
Negative Genetic |
JJJ3 |
YJR097W |
Iron-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
URA8 |
YJR103W |
Minor CTP synthase isozyme (see also URA7) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Negative Genetic |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
IOC2 |
YLR095C |
Subunit of the Isw1b complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI7 |
YLR237W |
Plasma membrane transporter responsible for the uptake of thiamine |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL013W-A |
YOL013W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIR2 |
YOR010C |
Putative cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
MFM1 |
YPL060W |
Mitochondrial inner membrane magnesium transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
1 |
1 |
1 |
Negative Genetic |
POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL247C |
YPL247C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL264C |
YPL264C |
Endoplasmic reticulum protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDL2 |
YPL270W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIP41 |
YPR040W |
Tap42p-interacting protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
MSH6 |
YDR097C |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ILV2 |
YMR108W |
Acetolactate synthase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL80 |
YKR034W |
Negative regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
physical |
1 |
1 |
1 |
Co-localization |
ENV11 |
YGR071C |
Protein proposed to be involved in vacuolar functions |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASG1 |
YIL130W |
Zinc cluster protein proposed to be a transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIS1 |
YDR096W |
Histone demethylase and transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
AGA1 |
YNR044W |
Anchorage subunit of a-agglutinin of a-cells |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG41 |
YPL250C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
FSF1 |
YOR271C |
Putative protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |