Standard name Systematic name Name description Description
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I Nucleolar protein that mediates homolog segregation during meiosis I; forms a complex with Lrs4p and then Mam1p at kinetochores; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation
Visualize the interactome of CSM1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 68

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.058 0.058 0.070
Endosome 0.173 0.128 0.099
Mito 0.173 0.360 NaN
Nucleolus 0.250 0.233 0.070
Nucleus 0.173 0.116 0.211
SpindlePole 0.067 NaN 0.423
Vac/Vac Memb 0.317 0.337 0.239
Budneck NaN NaN 0.056

GFP localization & abundance

GFP localization GFP abundance
nucleolus 1920

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CSM1 0 4 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 18 6 13 Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure, Affinity Capture-MS, Co-localization, Co-localization
MAM1 YER106W Monopolin physical 9 5 7 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation physical 8 4 7 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 8 3 6 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SRC1 YML034W Inner nuclear membrane protein physical 8 3 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 7 4 5 Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex
NUR1 YDL089W Protein involved in regulation of mitotic exit physical 6 2 5 Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 6 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 6 2 4 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 6 2 4 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 6 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 6 4 3 Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
POL32 YJR043C Third subunit of DNA polymerase delta genetic 6 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 5 2 5 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic
DSE3 YOR264W Daughter cell-specific protein, may help establish daughter fate physical 5 2 5 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Co-crystal Structure
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I physical 5 3 4 Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure
ASF1 YJL115W Nucleosome assembly factor genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PRR1 YKL116C Serine/threonine protein kinase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 4 2 3 Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 4 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 4 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
NFI1 YOR156C SUMO E3 ligase genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SAC3 YDR159W mRNA export factor genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 3 3 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 3 2 3 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 3 3 2 Negative Genetic, Synthetic Growth Defect, Synthetic Lethality
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 3 2 2 Negative Genetic, Negative Genetic, Positive Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSN5 YDR335W Karyopherin genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HHT2 YNL031C Histone H3 genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PUF4 YGL014W Member of the PUF protein family genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OCA2 YNL056W Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YPR084W YPR084W Putative protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ATS1 YAL020C Protein required for modification of wobble nucleosides in tRNA genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 2 2 Positive Genetic, Phenotypic Enhancement
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 2 2 2 Phenotypic Suppression, Negative Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 2 2 2 Phenotypic Suppression, Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 2 2 Synthetic Lethality, Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 2 1 2 Negative Genetic, Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 2 1 2 Negative Genetic, Negative Genetic
SPO12 YHR152W Nucleolar protein of unknown function physical 2 1 2 Two-hybrid, Two-hybrid
SMC4 YLR086W Subunit of the condensin complex physical 2 1 2 Two-hybrid, Two-hybrid
PLP2 YOR281C Protein that interacts with the CCT complex to stimulate actin folding physical 2 1 2 Two-hybrid, Two-hybrid
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SLK19 YOR195W Kinetochore-associated protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport genetic 2 1 2 Negative Genetic, Negative Genetic
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 2 1 2 Negative Genetic, Negative Genetic
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 2 1 2 Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 2 1 2 Negative Genetic, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
YET1 YKL065C Endoplasmic reticulum transmembrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 2 1 2 Negative Genetic, Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 2 1 2 Positive Genetic, Positive Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 2 1 2 Negative Genetic, Negative Genetic
PFK27 YOL136C 6-phosphofructo-2-kinase genetic 2 1 2 Negative Genetic, Negative Genetic
SFG1 YOR315W Nuclear protein putative transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 2 1 2 Negative Genetic, Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
SMC2 YFR031C Subunit of the condensin complex genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 2 1 2 Positive Genetic, Positive Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex genetic 2 1 2 Negative Genetic, Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 2 Negative Genetic, Negative Genetic
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) genetic 2 1 2 Negative Genetic, Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 2 1 2 Negative Genetic, Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 2 1 2 Positive Genetic, Positive Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 2 1 2 Negative Genetic, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Positive Genetic, Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex physical 2 2 1 Two-hybrid, Affinity Capture-Western
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 2 2 1 Affinity Capture-Western, Co-localization
RAD52 YML032C Protein involved in homologous recombination genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 2 1 1 Negative Genetic, Negative Genetic
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
UBP14 YBR058C Ubiquitin-specific protease genetic 2 1 1 Positive Genetic, Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 2 1 1 Negative Genetic, Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 2 1 1 Negative Genetic, Negative Genetic
PCL6 YER059W Pho85p cyclin of the Pho80p subfamily genetic 2 1 1 Negative Genetic, Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 2 1 1 Negative Genetic, Negative Genetic
VSB1 YGR125W Vacuolar membrane protein required for uptake and storage of arginine genetic 2 1 1 Negative Genetic, Negative Genetic
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) genetic 2 1 1 Negative Genetic, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 2 1 1 Positive Genetic, Positive Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 2 1 1 Positive Genetic, Positive Genetic
CTF4 YPR135W Chromatin-associated protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD18 YCR066W E3 ubiquitin ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD57 YDR004W Protein that stimulates strand exchange genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD55 YDR076W Protein that stimulates strand exchange genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RAD51 YER095W Strand exchange protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DIA2 YOR080W Origin-binding F-box protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 1 1 Negative Genetic, Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 2 1 1 Negative Genetic, Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 2 1 1 Negative Genetic, Negative Genetic
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 1 1 Negative Genetic, Negative Genetic
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 2 1 1 Negative Genetic, Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 2 1 1 Negative Genetic, Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Positive Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) physical 1 1 1 Two-hybrid
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Phenotypic Suppression
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Positive Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Negative Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III physical 1 1 1 Two-hybrid
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Positive Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Positive Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Growth Defect
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Two-hybrid
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 Two-hybrid
RAD10 YML095C Single-stranded DNA endonuclease (with Rad1p) physical 1 1 1 Two-hybrid
SAE2 YGL175C Endonuclease required for telomere elongation physical 1 1 1 Two-hybrid
SPO12 YHR152W Nucleolar protein of unknown function genetic 1 1 1 Synthetic Rescue
TAT2 YOL020W High affinity tryptophan and tyrosine permease physical 1 1 1 Two-hybrid
YDR061W YDR061W Protein with similarity to ABC transporter family members physical 1 1 1 Two-hybrid
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Two-hybrid
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector physical 1 1 1 Two-hybrid
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Co-localization
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities physical 1 1 1 Two-hybrid
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities genetic 1 1 1 Phenotypic Suppression
NUR1 YDL089W Protein involved in regulation of mitotic exit genetic 1 1 1 Phenotypic Suppression
MCM3 YEL032W Protein involved in DNA replication physical 1 1 1 Affinity Capture-Western
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-Western
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Phenotypic Suppression
SMC1 YFL008W Subunit of the multiprotein cohesin complex physical 1 1 1 Two-hybrid
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Affinity Capture-MS
YGR126W YGR126W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription physical 1 1 1 Affinity Capture-MS
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
STN1 YDR082W Telomere end-binding and capping protein physical 1 1 1 Two-hybrid
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
MSN5 YDR335W Karyopherin physical 1 1 1 Two-hybrid
MCM10 YIL150C Essential chromatin-associated protein physical 1 1 1 Two-hybrid
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth physical 1 1 1 Two-hybrid
YOL036W YOL036W Protein of unknown function physical 1 1 1 Two-hybrid
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) physical 1 1 1 Two-hybrid
RPO26 YPR187W RNA polymerase subunit ABC23 physical 1 1 1 Two-hybrid
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation physical 1 1 1 Two-hybrid
GPX2 YBR244W Phospholipid hydroperoxide glutathione peroxidase physical 1 1 1 Two-hybrid
TRX3 YCR083W Mitochondrial thioredoxin physical 1 1 1 Two-hybrid
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways physical 1 1 1 Two-hybrid
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis physical 1 1 1 Two-hybrid
UBP5 YER144C Putative ubiquitin-specific protease physical 1 1 1 Two-hybrid
GZF3 YJL110C GATA zinc finger protein physical 1 1 1 Two-hybrid
YIL152W YIL152W Putative protein of unknown function physical 1 1 1 Two-hybrid
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Two-hybrid
SKP2 YNL311C F-box protein of unknown function physical 1 1 1 Two-hybrid
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
YCG1 YDR325W Subunit of the condensin complex physical 1 1 1 Two-hybrid
PRR2 YDL214C Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
MIF2 YKL089W Centromeric CDEIII region binding protein physical 1 1 1 Reconstituted Complex
MTW1 YAL034W-A Essential component of the MIND kinetochore complex physical 1 1 1 Affinity Capture-Western
NSL1 YPL233W Essential component of the MIND kinetochore complex physical 1 1 1 Affinity Capture-Western
NNF1 YJR112W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-Western
SIR3 YLR442C Silencing protein physical 1 1 1 Co-localization
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 1 1 1 Co-localization
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Enhancement
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site physical 1 1 1 Co-localization
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site genetic 1 1 1 Phenotypic Suppression
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Synthetic Lethality
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination genetic 1 1 1 Synthetic Rescue
THP1 YOL072W Nuclear pore-associated protein genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Negative Genetic
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Phenotypic Enhancement
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
URC2 YDR520C Putative Zn(II)2Cys6 motif containing transcription factor genetic 1 1 1 Negative Genetic
YGR017W YGR017W Putative protein of unknown function genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Positive Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Positive Genetic
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Positive Genetic
LSM4 YER112W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Synthetic Growth Defect
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Synthetic Growth Defect
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Synthetic Growth Defect
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Synthetic Growth Defect
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Synthetic Growth Defect
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Synthetic Growth Defect
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Synthetic Growth Defect
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Synthetic Growth Defect
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Synthetic Growth Defect
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Synthetic Growth Defect
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Synthetic Growth Defect
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Synthetic Growth Defect
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Synthetic Growth Defect
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Lethality
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Synthetic Lethality
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate genetic 1 1 1 Synthetic Lethality
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Synthetic Lethality
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Lethality
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Lethality
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
MTR4 YJL050W RNA duplex-sensing translocase genetic 1 1 1 Positive Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Positive Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Positive Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Positive Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Positive Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Positive Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Positive Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Positive Genetic
MUM2 YBR057C Protein essential for meiotic DNA replication and sporulation genetic 1 1 1 Positive Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Positive Genetic
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 1 1 1 Positive Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Positive Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Positive Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Positive Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Positive Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Positive Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Positive Genetic
FDO1 YMR144W Protein involved in directionality of mating type switching genetic 1 1 1 Positive Genetic
FAP1 YNL023C Protein that binds to Fpr1p genetic 1 1 1 Positive Genetic
YNL058C YNL058C Putative protein of unknown function genetic 1 1 1 Positive Genetic
MDM31 YHR194W Mitochondrial protein that may have a role in phospholipid metabolism genetic 1 1 1 Positive Genetic
RIB5 YBR256C Riboflavin synthase genetic 1 1 1 Negative Genetic
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
THG1 YGR024C tRNAHis guanylyltransferase genetic 1 1 1 Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
FUR1 YHR128W Uracil phosphoribosyltransferase genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I genetic 1 1 1 Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Negative Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 genetic 1 1 1 Negative Genetic
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity genetic 1 1 1 Negative Genetic
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
YOS9 YDR057W ER quality-control lectin genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
FIN1 YDR130C Spindle pole body-related intermediate filament protein genetic 1 1 1 Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SEG1 YMR086W Component of eisosome required for proper eisosome assembly genetic 1 1 1 Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
CUE1 YMR264W Ubiquitin-binding protein genetic 1 1 1 Negative Genetic
RCM1 YNL022C rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
DUF1 YOL087C Ubiquitin-binding protein of unknown function genetic 1 1 1 Negative Genetic
SFA1 YDL168W Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
MSS116 YDR194C Mitochondrial transcription elongation factor genetic 1 1 1 Negative Genetic
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Negative Genetic
FMP48 YGR052W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Negative Genetic
ECM29 YHL030W Scaffold protein genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Negative Genetic
NBL1 YHR199C-A Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
TIF2 YJL138C Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Negative Genetic
JHD2 YJR119C JmjC domain family histone demethylase genetic 1 1 1 Negative Genetic
EFM3 YJR129C S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
SDH1 YKL148C Flavoprotein subunit of succinate dehydrogenase genetic 1 1 1 Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
FRE6 YLL051C Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Negative Genetic
IOC2 YLR095C Subunit of the Isw1b complex genetic 1 1 1 Negative Genetic
SSP120 YLR250W Protein packaged into COPII vesicles for ER to Golgi trafficking genetic 1 1 1 Negative Genetic
YLR285C-A YLR285C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
YMR001C-A YMR001C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RSF1 YMR030W Protein required for respiratory growth genetic 1 1 1 Negative Genetic
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
VID27 YNL212W Cytoplasmic protein of unknown function genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p genetic 1 1 1 Negative Genetic
DCI1 YOR180C Peroxisomal protein genetic 1 1 1 Negative Genetic
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Negative Genetic
PUS7 YOR243C Pseudouridine synthase genetic 1 1 1 Negative Genetic
HRK1 YOR267C Protein kinase genetic 1 1 1 Negative Genetic
YOR385W YOR385W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Positive Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Positive Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Positive Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Positive Genetic
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic genetic 1 1 1 Positive Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Positive Genetic
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
NIS1 YNL078W Protein involved in axial bud site selection genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Positive Genetic
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Synthetic Growth Defect
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
CQD1 YPL109C UbiB family mitochondrial protein physical 1 1 1 Two-hybrid
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum physical 1 1 1 Affinity Capture-MS
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Synthetic Lethality