Standard name Systematic name Name description Description
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family; involved in mRNA export from the nucleus, remodeling messenger ribonucleoprotein particles (mRNPs), with ATPase activity stimulated by Gle1p, IP6 and Nup159p; involved in translation termination along with Sup45p (eRF1); role in the cellular response to heat stress
Visualize the interactome of DBP5
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
ER 0.060 0.125 0.062
Nuc Periphery 0.188 0.250 0.312
Nucleolus 0.101 0.125 0.062
Vac/Vac Memb 0.758 0.750 0.625
Cort. Patches NaN 0.062 NaN
Cytoplasm NaN 0.062 NaN
Mito NaN NaN 0.125

GFP localization & abundance

GFP localization GFP abundance
nuclear periphery 14900

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
DBP5 4 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex genetic 9 5 8 Synthetic Lethality, Synthetic Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export physical 9 5 6 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Biochemical Activity, Two-hybrid, Biochemical Activity, Co-crystal Structure, Two-hybrid
GFD1 YMR255W Coiled-coiled protein of unknown function genetic 8 5 5 Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Dosage Rescue, Synthetic Rescue, Synthetic Lethality, Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 7 4 7 Dosage Rescue, Synthetic Lethality, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Growth Defect, Negative Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 7 3 7 Dosage Rescue, Synthetic Lethality, Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 7 4 6 Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 7 5 5 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, PCA
LSM1 YJL124C Lsm (Like Sm) protein genetic 6 4 5 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Positive Genetic, Synthetic Growth Defect
SAC3 YDR159W mRNA export factor genetic 5 3 4 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 5 3 4 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Positive Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 5 3 4 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
SLX9 YGR081C Protein required for pre-rRNA processing genetic 5 3 4 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
LSM7 YNL147W Lsm (Like Sm) protein genetic 5 3 4 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 5 3 4 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 5 3 4 Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 5 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
CRM1 YGR218W Nuclear export factor, exportin genetic 4 2 4 Dosage Rescue, Dosage Rescue, Dosage Rescue, Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 4 3 3 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
GFD1 YMR255W Coiled-coiled protein of unknown function physical 4 3 3 Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 4 3 3 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 4 3 3 Co-fractionation, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
THP1 YOL072W Nuclear pore-associated protein genetic 4 3 3 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect
HTZ1 YOL012C Histone variant H2AZ genetic 3 3 3 Negative Genetic, Synthetic Lethality, Synthetic Growth Defect
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 3 2 3 Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect
THP2 YHR167W Subunit of the THO and TREX complexes genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 3 3 2 Synthetic Lethality, Negative Genetic, Positive Genetic
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
CIK1 YMR198W Kinesin-associated protein genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
BAS1 YKR099W Myb-related transcription factor genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
DST1 YGL043W General transcription elongation factor TFIIS genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Positive Genetic
HTA1 YDR225W Histone H2A genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
KAR3 YPR141C Minus-end-directed microtubule motor genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
SIT4 YDL047W Ceramide-activated, type 2A-related serine-threonine phosphatase genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
BRE5 YNR051C Ubiquitin protease cofactor genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SAC3 YDR159W mRNA export factor physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 2 2 2 Synthetic Lethality, Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 2 2 2 Synthetic Lethality, Negative Genetic
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 2 2 2 Synthetic Lethality, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 2 2 Synthetic Lethality, Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 2 2 2 Dosage Growth Defect, Negative Genetic
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 2 2 Synthetic Lethality, Positive Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SUP35 YDR172W Translation termination factor eRF3 genetic 2 2 2 Dosage Rescue, Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 2 2 2 Negative Genetic, Positive Genetic
RUD3 YOR216C Golgi matrix protein genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
POM33 YLL023C Transmembrane nucleoporin genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
OCA2 YNL056W Protein of unknown function genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
YNL140C YNL140C Protein of unknown function genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PAB1 YER165W Poly(A) binding protein physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
PUF4 YGL014W Member of the PUF protein family genetic 2 1 2 Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 1 2 Negative Genetic, Negative Genetic
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth physical 2 2 1 Two-hybrid, Reconstituted Complex
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 1 Affinity Capture-Western, PCA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RLI1 YDR091C Essential Fe-S protein physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SKI3 YPR189W Ski complex component and TPR protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SWC5 YBR231C Component of the SWR1 complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SSD1 YDR293C Translational repressor genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
UBP14 YBR058C Ubiquitin-specific protease genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RPL39 YJL189W Ribosomal 60S subunit protein L39 genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
CBS1 YDL069C Mitochondrial translational activator of the COB mRNA genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Positive Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Synthetic Growth Defect
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Synthetic Lethality
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Synthetic Growth Defect
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
ATP11 YNL315C Molecular chaperone genetic 1 1 1 Synthetic Growth Defect
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Affinity Capture-MS
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Synthetic Growth Defect
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Synthetic Rescue
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-Western
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Lethality
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Synthetic Growth Defect
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization genetic 1 1 1 Synthetic Growth Defect
BUD13 YGL174W Subunit of the RES complex genetic 1 1 1 Positive Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Synthetic Growth Defect
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Synthetic Growth Defect
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Synthetic Growth Defect
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Synthetic Growth Defect
CUE5 YOR042W Ubiquitin-binding protein genetic 1 1 1 Synthetic Growth Defect
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Positive Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
COG1 YGL223C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Synthetic Growth Defect
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
RAD3 YER171W 5' to 3' DNA helicase physical 1 1 1 Affinity Capture-Western
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes physical 1 1 1 Affinity Capture-Western
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes physical 1 1 1 Affinity Capture-Western
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Synthetic Lethality
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Dosage Rescue
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination genetic 1 1 1 Dosage Rescue
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Phenotypic Suppression
MPP6 YNR024W Nuclear exosome-associated RNA binding protein physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway physical 1 1 1 Affinity Capture-MS
MOB1 YIL106W Component of the mitotic exit network physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
NFI1 YOR156C SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-Western
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit physical 1 1 1 Affinity Capture-Western
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Affinity Capture-Western
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Reconstituted Complex
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Synthetic Lethality
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
MYG1 YER156C Protein involved in mitochondrial function physical 1 1 1 Proximity Label-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 Affinity Capture-Western
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
SRB4 YER022W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Rescue
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Synthetic Rescue
ZDS2 YML109W Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Synthetic Lethality
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Dosage Rescue
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Dosage Rescue
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
TRM10 YOL093W tRNA methyltransferase genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
EFB1 YAL003W Translation elongation factor 1 beta genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Negative Genetic
TSR3 YOR006C Protein required for 20S pre-rRNA processing genetic 1 1 1 Negative Genetic
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
NRP1 YDL167C Putative RNA binding protein of unknown function genetic 1 1 1 Positive Genetic
NUR1 YDL089W Protein involved in regulation of mitotic exit genetic 1 1 1 Positive Genetic
TRM1 YDR120C tRNA methyltransferase genetic 1 1 1 Positive Genetic
RNH70 YGR276C 3'-5' exoribonuclease genetic 1 1 1 Positive Genetic
TRM9 YML014W tRNA methyltransferase genetic 1 1 1 Positive Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Synthetic Lethality
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 1 1 1 Synthetic Lethality
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Synthetic Lethality
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Synthetic Lethality
EXO1 YOR033C 5'-3' exonuclease and flap-endonuclease genetic 1 1 1 Synthetic Lethality
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Synthetic Lethality
REF2 YDR195W RNA-binding protein genetic 1 1 1 Synthetic Lethality
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Synthetic Lethality
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Synthetic Lethality
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Synthetic Lethality
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Synthetic Lethality
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Synthetic Lethality
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Lethality
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Synthetic Lethality
RPL34B YIL052C Ribosomal 60S subunit protein L34B genetic 1 1 1 Synthetic Lethality
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 1 1 1 Synthetic Lethality
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B genetic 1 1 1 Synthetic Lethality
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Synthetic Lethality
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Synthetic Lethality
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Synthetic Lethality
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Synthetic Lethality
YBR259W YBR259W Protein of unknown function genetic 1 1 1 Synthetic Lethality
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Synthetic Lethality
EFG1 YGR271C-A Ribosome biogenesis factor required for maturation of 18S rRNA genetic 1 1 1 Synthetic Lethality
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Synthetic Lethality
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Synthetic Lethality
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance genetic 1 1 1 Synthetic Lethality
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Synthetic Lethality
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Synthetic Lethality
PEX6 YNL329C AAA-peroxin genetic 1 1 1 Synthetic Lethality
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Synthetic Lethality
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Lethality
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Synthetic Lethality
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Synthetic Lethality
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Synthetic Lethality
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Synthetic Lethality
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Synthetic Lethality
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Synthetic Lethality
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Synthetic Growth Defect
TOA2 YKL058W TFIIA small subunit genetic 1 1 1 Synthetic Growth Defect
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Positive Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
DSL1 YNL258C Peripheral membrane protein needed for Golgi-to-ER retrograde traffic genetic 1 1 1 Positive Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Positive Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Positive Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Positive Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Positive Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
RMD5 YDR255C Component of GID Complex that confers ubiquitin ligase (U3) activity genetic 1 1 1 Positive Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Positive Genetic
SPO74 YGL170C Component of the meiotic outer plaque of the spindle pole body genetic 1 1 1 Positive Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Positive Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
YKR015C YKR015C Putative protein of unknown function genetic 1 1 1 Positive Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
YLR287C YLR287C Putative protein of unknown function genetic 1 1 1 Positive Genetic
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Positive Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Positive Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Positive Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Positive Genetic
SDD4 YPR022C Putative transcription factor, as suggested by computational analysis genetic 1 1 1 Positive Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
RRP42 YDL111C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Negative Genetic
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
PDS1 YDR113C Securin genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
RRP45 YDR280W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SKI6 YGR195W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
MTR4 YJL050W RNA duplex-sensing translocase genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
PEX32 YBR168W Peroxisomal integral membrane protein genetic 1 1 1 Negative Genetic
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
TAH1 YCR060W Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
KIN82 YCR091W Putative serine/threonine protein kinase genetic 1 1 1 Negative Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Negative Genetic
RPL41B YDL133C-A Ribosomal 60S subunit protein L41B genetic 1 1 1 Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
OCA6 YDR067C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
SSF2 YDR312W Protein required for ribosomal large subunit maturation genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Negative Genetic
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p genetic 1 1 1 Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Negative Genetic
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 1 1 1 Negative Genetic
YGR079W YGR079W Protein of unknown function genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
YLL032C YLL032C Protein of unknown function genetic 1 1 1 Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Negative Genetic
RPS22B YLR367W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 1 1 1 Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Negative Genetic
UIP4 YPL186C Protein that interacts with Ulp1p genetic 1 1 1 Negative Genetic
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Synthetic Growth Defect
RSB1 YOR049C Sphingoid long-chain base (LCB) efflux transporter genetic 1 1 1 Synthetic Growth Defect
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus genetic 1 1 1 Synthetic Growth Defect
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Synthetic Growth Defect
PFA4 YOL003C Palmitoyltransferase with autoacylation activity genetic 1 1 1 Synthetic Growth Defect
TMC1 YOR052C AN1-type zinc finger protein, effector of proteotoxic stress response genetic 1 1 1 Synthetic Growth Defect
IRC23 YOR044W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Synthetic Growth Defect
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Synthetic Growth Defect
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Synthetic Growth Defect
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Synthetic Growth Defect
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors genetic 1 1 1 Synthetic Growth Defect
TOM6 YOR045W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Synthetic Growth Defect
FMP52 YER004W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
EXP1 YDL121C A cargo receptor protein for Pma1p genetic 1 1 1 Synthetic Growth Defect
YOR019W YOR019W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
THR1 YHR025W Homoserine kinase genetic 1 1 1 Synthetic Growth Defect
LPX1 YOR084W Peroxisomal matrix-localized lipase genetic 1 1 1 Synthetic Growth Defect
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Synthetic Growth Defect
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Synthetic Growth Defect
SET4 YJL105W Chromatin-associated protein involved in control of stress response genetic 1 1 1 Synthetic Growth Defect
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Synthetic Growth Defect
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
SFM1 YOR021C SPOUT methyltransferase genetic 1 1 1 Synthetic Growth Defect
GEP4 YHR100C Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) genetic 1 1 1 Synthetic Growth Defect
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Synthetic Growth Defect
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Synthetic Growth Defect
RPL27A YHR010W Ribosomal 60S subunit protein L27A genetic 1 1 1 Synthetic Growth Defect
MDM31 YHR194W Mitochondrial protein that may have a role in phospholipid metabolism genetic 1 1 1 Synthetic Growth Defect
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Synthetic Growth Defect
RCY1 YJL204C F-box protein involved in recycling endocytosed proteins genetic 1 1 1 Synthetic Growth Defect
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Synthetic Growth Defect
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 1 1 1 Synthetic Growth Defect
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Synthetic Growth Defect
LIP2 YLR239C Lipoyl ligase genetic 1 1 1 Synthetic Growth Defect
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Synthetic Growth Defect
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Synthetic Growth Defect
IRC10 YOL015W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
MCX1 YBR227C Non-proteolytic ATPase of the AAA family genetic 1 1 1 Synthetic Growth Defect
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Synthetic Growth Defect
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Synthetic Growth Defect
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Synthetic Growth Defect
RRG1 YDR065W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
FSH2 YMR222C Putative serine hydrolase that localizes to the cytoplasm genetic 1 1 1 Synthetic Growth Defect
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Synthetic Growth Defect
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Synthetic Growth Defect
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Synthetic Growth Defect
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Synthetic Growth Defect
DOC1 YGL240W Processivity factor genetic 1 1 1 Synthetic Growth Defect
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
TYR1 YBR166C Prephenate dehydrogenase involved in tyrosine biosynthesis genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Synthetic Growth Defect
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
TCB1 YOR086C Lipid-binding ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Synthetic Growth Defect
SNF7 YLR025W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Synthetic Growth Defect
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Synthetic Growth Defect
NRT1 YOR071C High-affinity nicotinamide riboside transporter genetic 1 1 1 Synthetic Growth Defect
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Synthetic Growth Defect
KTR7 YIL085C Putative mannosyltransferase involved in protein glycosylation genetic 1 1 1 Synthetic Growth Defect
RSM22 YKL155C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Synthetic Growth Defect
MSW1 YDR268W Mitochondrial tryptophanyl-tRNA synthetase genetic 1 1 1 Synthetic Growth Defect
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Synthetic Growth Defect
SNF8 YPL002C Component of the ESCRT-II complex genetic 1 1 1 Synthetic Growth Defect
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Synthetic Growth Defect
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Synthetic Growth Defect
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Synthetic Growth Defect
ESC1 YMR219W Protein involved in telomeric silencing genetic 1 1 1 Synthetic Growth Defect
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Synthetic Growth Defect
IAI11 YBL059W Putative mitochondrial protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PRM4 YPL156C Pheromone-regulated protein proposed to be involved in mating genetic 1 1 1 Synthetic Growth Defect
POG1 YIL122W DNA-binding transcriptional activator genetic 1 1 1 Synthetic Growth Defect
NGL1 YOL042W Putative endonuclease genetic 1 1 1 Synthetic Growth Defect
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Synthetic Growth Defect
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Synthetic Growth Defect
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Synthetic Growth Defect
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) genetic 1 1 1 Synthetic Growth Defect
SLZ1 YNL196C Sporulation-specific protein with a leucine zipper motif genetic 1 1 1 Synthetic Growth Defect
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Synthetic Growth Defect
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 1 1 1 Synthetic Growth Defect
TDA3 YHR009C Putative oxidoreductase involved in late endosome to Golgi transport genetic 1 1 1 Synthetic Growth Defect
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 1 1 1 Synthetic Growth Defect
HIS3 YOR202W Imidazoleglycerol-phosphate dehydratase genetic 1 1 1 Synthetic Growth Defect
RPL31A YDL075W Ribosomal 60S subunit protein L31A genetic 1 1 1 Synthetic Growth Defect
MRPL38 YKL170W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Synthetic Growth Defect
MRPL23 YOR150W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Synthetic Growth Defect
PET123 YOR158W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
SWC7 YLR385C Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Synthetic Growth Defect
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Synthetic Growth Defect
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
MRPS5 YBR251W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Synthetic Growth Defect
MDJ1 YFL016C Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity genetic 1 1 1 Synthetic Growth Defect
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Synthetic Growth Defect
MRS1 YIR021W Splicing protein genetic 1 1 1 Synthetic Growth Defect
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Synthetic Growth Defect
FYV7 YLR068W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Synthetic Growth Defect
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase genetic 1 1 1 Synthetic Growth Defect
MSN5 YDR335W Karyopherin genetic 1 1 1 Synthetic Growth Defect
LYS14 YDR034C Transcriptional activator involved in regulating lysine biosynthesis genetic 1 1 1 Synthetic Growth Defect
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Synthetic Growth Defect
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Synthetic Growth Defect
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Synthetic Growth Defect
SRF1 YDL133W Regulator of phospholipase D (Spo14p) genetic 1 1 1 Synthetic Growth Defect
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Synthetic Growth Defect
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Synthetic Growth Defect
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Synthetic Growth Defect
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Synthetic Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Synthetic Lethality
AUS1 YOR011W Plasma membrane sterol transporter of the ATP-binding cassette family genetic 1 1 1 Synthetic Growth Defect
AVT1 YJR001W Vacuolar transporter genetic 1 1 1 Synthetic Growth Defect
AIM22 YJL046W Lipoate-protein ligase genetic 1 1 1 Synthetic Growth Defect
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
CUE3 YGL110C Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Synthetic Growth Defect
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Synthetic Growth Defect
ADE12 YNL220W Adenylosuccinate synthase genetic 1 1 1 Synthetic Growth Defect
CMK2 YOL016C Calmodulin-dependent protein kinase genetic 1 1 1 Synthetic Growth Defect
CYC2 YOR037W Mitochondrial peripheral inner membrane protein genetic 1 1 1 Synthetic Growth Defect
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
AIM20 YIL158W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
ATX2 YOR079C Golgi membrane protein involved in manganese homeostasis genetic 1 1 1 Synthetic Growth Defect
ALG8 YOR067C Glucosyl transferase genetic 1 1 1 Synthetic Growth Defect
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Synthetic Growth Defect
AIF1 YNR074C Mitochondrial cell death effector genetic 1 1 1 Synthetic Growth Defect
BUD25 YER014C-A Protein involved in bud-site selection genetic 1 1 1 Synthetic Growth Defect