Standard name Systematic name Name description Description
PRE2 YPR103W Beta 5 subunit of the 20S proteasome Beta 5 subunit of the 20S proteasome; responsible for the chymotryptic activity of the proteasome
Visualize the interactome of PRE2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.887 0.969 0.962
Mito 0.126 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 8530

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PRE2 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 14 4 13 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRE1 YER012W Beta 4 subunit of the 20S proteasome genetic 11 5 9 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Rescue, Positive Genetic, Positive Genetic, Negative Genetic
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 8 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 7 3 7 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 7 3 6 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
PRE3 YJL001W Beta 1 subunit of the 20S proteasome physical 6 4 6 Affinity Capture-MS, Co-crystal Structure, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS
PUP3 YER094C Beta 3 subunit of the 20S proteasome physical 6 4 6 Co-crystal Structure, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 6 2 5 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRE8 YML092C Alpha 2 subunit of the 20S proteasome physical 6 2 5 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome physical 6 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 6 3 4 Synthetic Lethality, Positive Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 6 3 4 Dosage Rescue, Positive Genetic, Positive Genetic, Dosage Rescue, Negative Genetic, Negative Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome physical 5 3 5 Affinity Capture-MS, Co-crystal Structure, Co-purification, Affinity Capture-MS, Affinity Capture-MS
PRE7 YBL041W Beta 6 subunit of the 20S proteasome physical 5 2 5 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 5 2 5 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome physical 4 3 4 Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome physical 4 2 4 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
PRE4 YFR050C Beta 7 subunit of the 20S proteasome physical 4 2 4 Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 4 3 2 Synthetic Haploinsufficiency, Synthetic Haploinsufficiency, Positive Genetic, Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 4 2 2 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 4 2 2 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 4 2 2 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
BLM10 YFL007W Proteasome activator physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Protein-peptide
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 2 2 Negative Genetic, Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Negative Genetic, Positive Genetic
ECM29 YHL030W Scaffold protein physical 2 2 2 Co-purification, Affinity Capture-MS
DOA4 YDR069C Ubiquitin hydrolase genetic 2 2 2 Synthetic Rescue, Synthetic Growth Defect
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
HYP2 YEL034W Translation elongation factor eIF-5A genetic 2 2 2 Dosage Rescue, Negative Genetic
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 2 2 2 Positive Genetic, Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC63 YOR254C Essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 2 1 2 Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 2 Negative Genetic, Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 2 1 2 Negative Genetic, Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 2 1 2 Negative Genetic, Negative Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 2 Negative Genetic, Negative Genetic
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 2 1 2 Negative Genetic, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 2 2 1 Positive Genetic, Negative Genetic
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 2 2 1 Negative Genetic, Positive Genetic
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 2 2 1 Positive Genetic, Negative Genetic
YBR137W YBR137W Protein with a role in ER delivery of tail-anchored membrane proteins genetic 2 2 1 Positive Genetic, Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 2 2 1 Positive Genetic, Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 2 2 1 Positive Genetic, Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 2 2 1 Positive Genetic, Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 2 2 1 Positive Genetic, Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 2 2 1 Positive Genetic, Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 2 1 Positive Genetic, Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 2 2 1 Positive Genetic, Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 2 2 1 Positive Genetic, Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor genetic 2 2 1 Positive Genetic, Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 2 2 1 Positive Genetic, Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 2 2 1 Positive Genetic, Negative Genetic
DAN4 YJR151C Cell wall mannoprotein genetic 2 2 1 Positive Genetic, Negative Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 2 2 1 Positive Genetic, Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 2 1 1 Negative Genetic, Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 1 1 Negative Genetic, Negative Genetic
PRE3 YJL001W Beta 1 subunit of the 20S proteasome genetic 2 1 1 Positive Genetic, Positive Genetic
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome genetic 2 1 1 Positive Genetic, Positive Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
PRE8 YML092C Alpha 2 subunit of the 20S proteasome genetic 2 1 1 Positive Genetic, Positive Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 2 1 1 Negative Genetic, Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 2 1 1 Negative Genetic, Negative Genetic
RAD23 YEL037C Protein with ubiquitin-like N terminus physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 1 1 Positive Genetic, Positive Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 2 1 1 Positive Genetic, Positive Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 2 1 1 Positive Genetic, Positive Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 1 1 Negative Genetic, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 2 1 1 Negative Genetic, Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 2 1 1 Negative Genetic, Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 2 1 1 Negative Genetic, Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 2 1 1 Negative Genetic, Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 2 1 1 Negative Genetic, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 2 1 1 Negative Genetic, Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 2 1 1 Negative Genetic, Negative Genetic
URA6 YKL024C Uridylate kinase genetic 2 1 1 Negative Genetic, Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 2 1 1 Negative Genetic, Negative Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 2 1 1 Negative Genetic, Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 2 1 1 Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 1 1 Negative Genetic, Negative Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 2 1 1 Negative Genetic, Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 2 1 1 Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 2 1 1 Negative Genetic, Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 2 1 1 Negative Genetic, Negative Genetic
RPL9B YNL067W Ribosomal 60S subunit protein L9B genetic 2 1 1 Negative Genetic, Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 2 1 1 Negative Genetic, Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 2 1 1 Negative Genetic, Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
CDC53 YDL132W Cullin genetic 2 1 1 Negative Genetic, Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 2 1 1 Negative Genetic, Negative Genetic
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 2 1 1 Negative Genetic, Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 2 1 1 Negative Genetic, Negative Genetic
LDB17 YDL146W Protein involved in the regulation of endocytosis genetic 2 1 1 Negative Genetic, Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 1 1 Negative Genetic, Negative Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 1 1 Negative Genetic, Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 2 1 1 Negative Genetic, Negative Genetic
IRC8 YJL051W Bud tip localized protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 2 1 1 Negative Genetic, Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 1 1 1 Positive Genetic
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space genetic 1 1 1 Positive Genetic
PFK27 YOL136C 6-phosphofructo-2-kinase genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
KRE29 YER038C Subunit of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Co-purification
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Positive Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes physical 1 1 1 Co-purification
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Co-purification
UBC1 YDR177W Ubiquitin-conjugating enzyme physical 1 1 1 Co-purification
UBC1 YDR177W Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Co-purification
UBC5 YDR059C Ubiquitin-conjugating enzyme physical 1 1 1 Co-purification
UBR1 YGR184C E3 ubiquitin ligase (N-recognin) physical 1 1 1 Co-purification
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Co-purification
STD1 YOR047C Protein involved in control of glucose-regulated gene expression physical 1 1 1 Two-hybrid
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-Western
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Affinity Capture-MS
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Synthetic Lethality
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Synthetic Growth Defect
RAD18 YCR066W E3 ubiquitin ligase genetic 1 1 1 Phenotypic Suppression
RAD30 YDR419W DNA polymerase eta genetic 1 1 1 Phenotypic Suppression
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 1 1 1 Phenotypic Suppression
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Synthetic Growth Defect
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Positive Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Synthetic Lethality
SSA2 YLL024C HSP70 family ATP-binding protein genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
SEC61 YLR378C Conserved ER protein translocation channel genetic 1 1 1 Negative Genetic
TOS1 YBR162C Covalently-bound cell wall protein of unknown function genetic 1 1 1 Negative Genetic
SHE10 YGL228W Protein involved in outer spore wall assembly genetic 1 1 1 Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Negative Genetic
STE24 YJR117W Highly conserved zinc metalloprotease genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi genetic 1 1 1 Negative Genetic
SPT14 YPL175W UDP-glycosyltransferase subunit of the GPI-GnT complex genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 1 1 1 Negative Genetic
YPT35 YHR105W Endosomal protein of unknown function genetic 1 1 1 Negative Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Synthetic Growth Defect
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties genetic 1 1 1 Synthetic Rescue
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Dosage Rescue
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Positive Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
PWP2 YCR057C Conserved 90S pre-ribosomal component genetic 1 1 1 Positive Genetic
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor genetic 1 1 1 Positive Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Positive Genetic
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Positive Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Positive Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Positive Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Positive Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Positive Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Positive Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Positive Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Positive Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Positive Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Positive Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Positive Genetic
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Positive Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Positive Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Positive Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Positive Genetic
YML119W YML119W Putative protein of unknown function genetic 1 1 1 Positive Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Positive Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Positive Genetic
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Positive Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Positive Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Positive Genetic
RMR1 YGL250W Protein required for meiotic recombination and gene conversion genetic 1 1 1 Positive Genetic
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Positive Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Positive Genetic
YKR005C YKR005C Putative protein of unknown function genetic 1 1 1 Positive Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Positive Genetic
QRI5 YLR204W Mitochondrial inner membrane protein genetic 1 1 1 Positive Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Positive Genetic
TDA5 YLR426W Putative protein of unknown function genetic 1 1 1 Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Positive Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
RIB5 YBR256C Riboflavin synthase genetic 1 1 1 Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 1 1 1 Negative Genetic
RPC53 YDL150W RNA polymerase III subunit C53 genetic 1 1 1 Negative Genetic
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat genetic 1 1 1 Negative Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA genetic 1 1 1 Negative Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
YPP1 YGR198W Cargo-transport protein involved in endocytosis genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
UTP25 YIL091C Nucleolar protein genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Negative Genetic
TFA1 YKL028W TFIIE large subunit genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication genetic 1 1 1 Negative Genetic
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Negative Genetic
RRB1 YMR131C Specific assembly chaperone for ribosomal protein Rpl3p genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RKI1 YOR095C Ribose-5-phosphate ketol-isomerase genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
RRS1 YOR294W Essential protein that binds ribosomal protein L11 genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Negative Genetic
RRP3 YHR065C Protein involved in rRNA processing genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
SAM35 YHR083W Component of the sorting and assembly machinery (SAM) complex genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 1 1 1 Negative Genetic
THI3 YDL080C Regulatory protein that binds Pdc2p and Thi2p transcription factors genetic 1 1 1 Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Negative Genetic
TRM3 YDL112W 2'-O-ribose methyltransferase genetic 1 1 1 Negative Genetic
YDL129W YDL129W Protein of unknown function genetic 1 1 1 Negative Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Negative Genetic
SFA1 YDL168W Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase genetic 1 1 1 Negative Genetic
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
YER084W YER084W Protein of unknown function genetic 1 1 1 Negative Genetic
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
YHR078W YHR078W High osmolarity-regulated gene of unknown function genetic 1 1 1 Negative Genetic
SAE3 YHR079C-A Meiosis-specific protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Negative Genetic
RKR1 YMR247C RING domain E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
ROY1 YMR258C GTPase inhibitor with similarity to F-box proteins genetic 1 1 1 Negative Genetic
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Negative Genetic
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 1 1 1 Negative Genetic
YAL037C-A YAL037C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
YBL086C YBL086C Protein of unknown function genetic 1 1 1 Negative Genetic
RPL23A YBL087C Ribosomal 60S subunit protein L23A genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YBR062C YBR062C Protein of unknown function that interacts with Msb2p genetic 1 1 1 Negative Genetic
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck genetic 1 1 1 Negative Genetic
SLM4 YBR077C Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A genetic 1 1 1 Negative Genetic
YBR085C-A YBR085C-A Protein of unknown function genetic 1 1 1 Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
SSE2 YBR169C Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family genetic 1 1 1 Negative Genetic
SMY2 YBR172C GYF domain protein genetic 1 1 1 Negative Genetic
YBR184W YBR184W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBR221W-A YBR221W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VVS1 YBR241C Putative transporter, member of the sugar porter family genetic 1 1 1 Negative Genetic
TRX3 YCR083W Mitochondrial thioredoxin genetic 1 1 1 Negative Genetic
SLC1 YDL052C 1-acyl-sn-glycerol-3-phosphate acyltransferase genetic 1 1 1 Negative Genetic
YDL057W YDL057W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SYO1 YDL063C Transport adaptor or symportin genetic 1 1 1 Negative Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
TMA17 YDL110C Regulatory gamma subunit of fatty acid synthase (FAS) genetic 1 1 1 Negative Genetic
RPP1B YDL130W Ribosomal protein P1 beta genetic 1 1 1 Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
RRG1 YDR065W Protein of unknown function genetic 1 1 1 Negative Genetic
SHU2 YDR078C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
YDR169C-A YDR169C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
UGO1 YDR470C Outer membrane component of the mitochondrial fusion machinery genetic 1 1 1 Negative Genetic
RPL37B YDR500C Ribosomal 60S subunit protein L37B genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
RPL12A YEL054C Ribosomal 60S subunit protein L12A genetic 1 1 1 Negative Genetic
SIT1 YEL065W Ferrioxamine B transporter genetic 1 1 1 Negative Genetic
RPL34A YER056C-A Ribosomal 60S subunit protein L34A genetic 1 1 1 Negative Genetic
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
RPL23B YER117W Ribosomal 60S subunit protein L23B genetic 1 1 1 Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 1 1 1 Negative Genetic
YER175W-A YER175W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YFL041W-A YFL041W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
ROG1 YGL144C Lipase with specificity for monoacylglycerol genetic 1 1 1 Negative Genetic
TAD1 YGL243W tRNA-specific adenosine deaminase genetic 1 1 1 Negative Genetic
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Negative Genetic
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Negative Genetic
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Negative Genetic
RPL14B YHL001W Ribosomal 60S subunit protein L14B genetic 1 1 1 Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
SPO13 YHR014W Meiotic regulator genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
YHR212W-A YHR212W-A Pseudogenic fragment with similarity to flocculins genetic 1 1 1 Negative Genetic
YIL014C-A YIL014C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL16A YIL133C Ribosomal 60S subunit protein L16A genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
PRY1 YJL079C Lipid binding protein genetic 1 1 1 Negative Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Negative Genetic
SAG1 YJR004C Alpha-agglutinin of alpha-cells genetic 1 1 1 Negative Genetic
TDA4 YJR116W Protein distantly similar to ceramide synthases, Lag1p and Lac1p genetic 1 1 1 Negative Genetic
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YKL106C-A YKL106C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSH4 YKL124W Specificity factor required for Rsp5p-dependent ubiquitination genetic 1 1 1 Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
YKR070W YKR070W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPO75 YLL005C Meiosis-specific protein of unknown function genetic 1 1 1 Negative Genetic
YPS1 YLR120C Aspartic protease genetic 1 1 1 Negative Genetic
SPE4 YLR146C Spermine synthase genetic 1 1 1 Negative Genetic
YLR154C-H YLR154C-H Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Negative Genetic
RPL38 YLR325C Ribosomal 60S subunit protein L38 genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
TRM9 YML014W tRNA methyltransferase genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
YML100W-A YML100W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Negative Genetic
YML133C YML133C Putative Y' element ATP-dependent helicase genetic 1 1 1 Negative Genetic
VBA1 YMR088C Permease of basic amino acids in the vacuolar membrane genetic 1 1 1 Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
SPG4 YMR107W Protein required for high temperature survival during stationary phase genetic 1 1 1 Negative Genetic
YMR181C YMR181C Protein of unknown function genetic 1 1 1 Negative Genetic
SPG5 YMR191W Protein required for proteasome assembly during quiescence genetic 1 1 1 Negative Genetic
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Negative Genetic
YMR247W-A YMR247W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
SPS19 YNL202W Peroxisomal 2,4-dienoyl-CoA reductase genetic 1 1 1 Negative Genetic
RRG9 YNL213C Protein of unknown function genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 1 1 1 Negative Genetic
RPP2A YOL039W Ribosomal protein P2 alpha genetic 1 1 1 Negative Genetic
YOR032W-A YOR032W-A Protein of unknown function genetic 1 1 1 Negative Genetic
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 1 1 1 Negative Genetic
YOR365C YOR365C Putative protein involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
YOR376W-A YOR376W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR381W-A YOR381W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Negative Genetic
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 genetic 1 1 1 Negative Genetic
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I genetic 1 1 1 Negative Genetic
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Positive Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Negative Genetic
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 1 1 1 Affinity Capture-Western
ECM29 YHL030W Scaffold protein genetic 1 1 1 Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Negative Genetic
KRS1 YDR037W Lysyl-tRNA synthetase genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Positive Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance genetic 1 1 1 Negative Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Positive Genetic
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL20 YKR085C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Negative Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Positive Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Negative Genetic
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Positive Genetic
DOA4 YDR069C Ubiquitin hydrolase physical 1 1 1 Co-purification
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Positive Genetic
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Affinity Capture-MS
MRPL38 YKL170W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
NRP1 YDL167C Putative RNA binding protein of unknown function genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Rescue
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 1 1 1 Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Negative Genetic
FUN19 YAL034C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
FES1 YBR101C Hsp70 (Ssa1p) nucleotide exchange factor genetic 1 1 1 Negative Genetic
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Positive Genetic
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase genetic 1 1 1 Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 1 1 1 Negative Genetic
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 1 1 1 Co-purification
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Dosage Rescue
ATP4 YPL078C Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 1 1 1 Negative Genetic
ATP3 YBR039W Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
CAF120 YNL278W Part of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
PET112 YBL080C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Negative Genetic
HEF3 YNL014W Translational elongation factor EF-3 genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 1 1 1 Negative Genetic
LSB1 YGR136W Negative regulator of actin nucleation-promoting factor activity genetic 1 1 1 Negative Genetic
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Negative Genetic
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 1 1 1 Negative Genetic
ERG20 YJL167W Farnesyl pyrophosphate synthetase genetic 1 1 1 Negative Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
HUL5 YGL141W Multiubiquitin chain assembly factor (E4) genetic 1 1 1 Negative Genetic
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Positive Genetic
PBA1 YLR199C Protein involved in 20S proteasome assembly physical 1 1 1 Co-fractionation
ADD66 YKL206C Protein involved in 20S proteasome assembly physical 1 1 1 Co-fractionation
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Positive Genetic
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Negative Genetic
MAG2 YLR427W Cytoplasmic protein of unknown function genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Negative Genetic
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Negative Genetic
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Positive Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Positive Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Positive Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 1 1 1 Positive Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Rescue
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Negative Genetic
HXT5 YHR096C Hexose transporter with moderate affinity for glucose genetic 1 1 1 Negative Genetic
MFB1 YDR219C Mitochondria-associated F-box protein genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
FUB1 YCR076C Proteasome-binding protein physical 1 1 1 Affinity Capture-MS
FUB1 YCR076C Proteasome-binding protein genetic 1 1 1 Synthetic Growth Defect
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Negative Genetic
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 1 1 1 Negative Genetic
MRX1 YER077C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 1 1 1 Negative Genetic
NAS2 YIL007C Evolutionarily conserved 19S regulatory particle assembly-chaperone genetic 1 1 1 Negative Genetic
CPR2 YHR057C Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Positive Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Positive Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Positive Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Positive Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Positive Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
BDP1 YNL039W Essential subunit of RNA polymerase III transcription factor (TFIIIB) genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Synthetic Growth Defect
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Positive Genetic
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Negative Genetic
HAP1 YLR256W Zinc finger transcription factor genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
HAP4 YKL109W Transcription factor genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP) genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
CHS3 YBR023C Chitin synthase III genetic 1 1 1 Negative Genetic
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase genetic 1 1 1 Negative Genetic
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 1 1 1 Negative Genetic
HMRA1 YCR097W Silenced copy of a1 at HMR genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly genetic 1 1 1 Negative Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Positive Genetic
FAF1 YIL019W Protein required for pre-rRNA processing genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
LYS21 YDL131W Homocitrate synthase isozyme genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Negative Genetic
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Negative Genetic
INH1 YDL181W Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase genetic 1 1 1 Negative Genetic
IZH4 YOL101C Membrane protein involved in zinc ion homeostasis genetic 1 1 1 Negative Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Positive Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
NDJ1 YOL104C Protein that regulates meiotic SPB cohesion and telomere clustering genetic 1 1 1 Negative Genetic
MIG2 YGL209W Zinc finger transcriptional repressor genetic 1 1 1 Negative Genetic
AGP2 YBR132C Plasma membrane regulator of polyamine and carnitine transport genetic 1 1 1 Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 1 1 1 Positive Genetic
ATP14 YLR295C Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
HRD3 YLR207W ER membrane protein that plays a central role in ERAD genetic 1 1 1 Phenotypic Suppression
PHO11 YAR071W One of three repressible acid phosphatases genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
JIP4 YDR475C Protein of unknown function genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
CUL3 YGR003W Ubiquitin-protein ligase genetic 1 1 1 Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 1 1 1 Dosage Rescue
MEF1 YLR069C Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
ATG33 YLR356W Mitochondrial mitophagy-specific protein genetic 1 1 1 Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone physical 1 1 1 Co-fractionation
CUZ1 YNL155W Protein with a role in the ubiquitin-proteasome pathway genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
DNF1 YER166W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone physical 1 1 1 Co-fractionation
AIM23 YJL131C Mitochondrial translation initiation factor 3 (IF3, mIF3) genetic 1 1 1 Positive Genetic
IDP3 YNL009W Peroxisomal NADP-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
HEM12 YDR047W Uroporphyrinogen decarboxylase genetic 1 1 1 Negative Genetic
PEX32 YBR168W Peroxisomal integral membrane protein genetic 1 1 1 Negative Genetic
APD1 YBR151W 2Fe-2S cytosolic protein of unknown function genetic 1 1 1 Negative Genetic
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 1 1 1 Positive Genetic
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
AGE2 YIL044C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) genetic 1 1 1 Positive Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Positive Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Negative Genetic
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Negative Genetic
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Positive Genetic
DDP1 YOR163W Diadenosine and diphosphoinositol polyphosphate phosphatase genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
NRM1 YNR009W Transcriptional co-repressor of MBF-regulated gene expression genetic 1 1 1 Negative Genetic
KTR1 YOR099W Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
JJJ3 YJR097W Iron-binding protein genetic 1 1 1 Negative Genetic
PNP1 YLR209C Purine nucleoside phosphorylase genetic 1 1 1 Negative Genetic
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
HXT4 YHR092C High-affinity glucose transporter genetic 1 1 1 Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Positive Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
LSO2 YGR169C-A Ribosome-associated protein genetic 1 1 1 Negative Genetic
MSP1 YGR028W Highly-conserved N-terminally anchored AAA-ATPase genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
PEX22 YAL055W Putative peroxisomal membrane protein genetic 1 1 1 Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 1 1 1 Negative Genetic
NFU1 YKL040C Protein involved in Fe-S cluster transfer to mitochondrial clients genetic 1 1 1 Positive Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
ASP3-2 YLR157C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic
CTS1 YLR286C Endochitinase genetic 1 1 1 Positive Genetic
FLC3 YGL139W Putative FAD transporter, similar to Flc1p and Flc2p genetic 1 1 1 Negative Genetic
FEX2 YPL279C Protein involved in fluoride export genetic 1 1 1 Negative Genetic
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Positive Genetic
MHF2 YDL160C-A Component of the heterotetrameric MHF histone-fold complex genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Positive Genetic
MIC10 YCL057C-A Conserved component of the MICOS complex genetic 1 1 1 Positive Genetic
MRPL37 YBR268W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ERG8 YMR220W Phosphomevalonate kinase genetic 1 1 1 Positive Genetic
EGO2 YCR075W-A Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
HXT15 YDL245C Putative transmembrane polyol transporter genetic 1 1 1 Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
GAS4 YOL132W 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 1 1 1 Negative Genetic
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 1 1 1 Negative Genetic
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Positive Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
POF1 YCL047C Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT) genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Positive Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
LEU5 YHR002W Mitochondrial carrier protein genetic 1 1 1 Negative Genetic
DPA10 YLR307C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
PAU23 YLR037C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
NIT1 YIL164C Nitrilase genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Positive Genetic
MIN3 YMR182W-A Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
PAU20 YOL161C Protein of unknown function genetic 1 1 1 Negative Genetic