Standard name Systematic name Name description Description
SPB4 YFL002C Putative ATP-dependent RNA helicase Putative ATP-dependent RNA helicase; nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradients
Visualize the interactome of SPB4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.907 0.904 0.910
Nucleolus NaN 0.053 0.064

GFP localization & abundance

GFP localization GFP abundance
nucleolus, nucleus 5740

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SPB4 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NOP2 YNL061W rRNA m5C methyltransferase physical 6 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes physical 5 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
NOC2 YOR206W Protein involved in ribosome biogenesis physical 5 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CIC1 YHR052W Essential protein that interacts with proteasome components physical 5 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 5 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOP15 YNL110C Constituent of 66S pre-ribosomal particles physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BRX1 YOL077C Nucleolar protein physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
EBP2 YKL172W Required for 25S rRNA maturation and 60S ribosomal subunit assembly physical 3 2 3 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS
NOP4 YPL043W Nucleolar protein physical 3 2 3 Affinity Capture-MS, Two-hybrid, Two-hybrid
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
HAS1 YMR290C ATP-dependent RNA helicase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NSA1 YGL111W Constituent of 66S pre-ribosomal particles physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MAK5 YBR142W Essential nucleolar protein physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CDC73 YLR418C Component of the Paf1p complex genetic 2 2 2 Synthetic Lethality, Positive Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 2 2 2 Positive Genetic, Phenotypic Suppression
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Negative Genetic, Dosage Lethality
NOP16 YER002W Constituent of 66S pre-ribosomal particles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL3 YOR063W Ribosomal 60S subunit protein L3 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PUF6 YDR496C Pumilio-homology domain protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NSA2 YER126C Protein constituent of 66S pre-ribosomal particles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOG2 YNR053C Putative GTPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP13 YNL175C Nucleolar protein found in preribosomal complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPB1 YCL054W AdoMet-dependent methyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL1A YPL220W Ribosomal 60S subunit protein L1A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL20A YMR242C Ribosomal 60S subunit protein L20A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL8B YLL045C Ribosomal 60S subunit protein L8A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
RIX7 YLL034C Putative ATPase of the AAA family physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Positive Genetic
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Positive Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 1 1 1 Affinity Capture-MS
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Affinity Capture-MS
ERB1 YMR049C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
MAK16 YAL025C Essential nuclear protein physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
RPL27A YHR010W Ribosomal 60S subunit protein L27A physical 1 1 1 Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Affinity Capture-MS
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes physical 1 1 1 Affinity Capture-MS
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family physical 1 1 1 Affinity Capture-MS
SMB1 YER029C Core Sm protein Sm B physical 1 1 1 Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p genetic 1 1 1 Negative Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 1 1 1 Negative Genetic
RRP14 YKL082C Essential protein, constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
NAN1 YPL126W U3 snoRNP protein physical 1 1 1 Affinity Capture-MS
PWP2 YCR057C Conserved 90S pre-ribosomal component physical 1 1 1 Affinity Capture-Western
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis physical 1 1 1 Affinity Capture-MS
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Affinity Capture-MS
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Affinity Capture-MS
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 Affinity Capture-MS
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
FUN12 YAL035W Translation initiation factor eIF5B physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
ALB1 YJL122W Shuttling pre-60S factor physical 1 1 1 Affinity Capture-MS
MTR4 YJL050W RNA duplex-sensing translocase physical 1 1 1 Affinity Capture-Western
PUS7 YOR243C Pseudouridine synthase genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Positive Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
PRP3 YDR473C Splicing factor genetic 1 1 1 Negative Genetic
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Positive Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Synthetic Rescue
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Positive Genetic
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 genetic 1 1 1 Negative Genetic
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RPC19 YNL113W RNA polymerase subunit AC19 physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-MS
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Positive Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Positive Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Positive Genetic
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Positive Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-MS
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE3 YJL001W Beta 1 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
PRE8 YML092C Alpha 2 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-MS
PUS1 YPL212C tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
SDA1 YGR245C Protein required for actin organization and passage through Start genetic 1 1 1 Negative Genetic
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) physical 1 1 1 Affinity Capture-MS
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Positive Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Affinity Capture-MS
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase genetic 1 1 1 Negative Genetic
FAP1 YNL023C Protein that binds to Fpr1p genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
GCN3 YKR026C Alpha subunit of translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
GTR2 YGR163W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Positive Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Negative Genetic
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
KGD2 YDR148C Dihydrolipoyl transsuccinylase physical 1 1 1 Affinity Capture-MS
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Positive Genetic
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 1 1 1 Affinity Capture-MS
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
LST8 YNL006W Protein required for the transport of Gap1p physical 1 1 1 Affinity Capture-MS
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Positive Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
IMG1 YCR046C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MHR1 YDR296W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRM1 YOR201C Ribose methyltransferase physical 1 1 1 Affinity Capture-MS
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL16 YBL038W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL13 YKR006C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL20 YKR085C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL28 YDR462W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL4 YLR439W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL7 YDR237W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRH4 YGL064C Mitochondrial ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair physical 1 1 1 Affinity Capture-MS
MLC1 YGL106W Essential light chain for Myo1p physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ physical 1 1 1 Affinity Capture-MS
LYS12 YIL094C Homo-isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 1 1 1 Affinity Capture-MS
MRPL15 YLR312W-A Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL3 YMR024W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
PRE4 YFR050C Beta 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
PTC3 YBL056W Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
PAA1 YDR071C Polyamine acetyltransferase physical 1 1 1 Affinity Capture-MS
NRP1 YDL167C Putative RNA binding protein of unknown function genetic 1 1 1 Negative Genetic
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome genetic 1 1 1 Positive Genetic
DBP8 YHR169W ATPase, putative RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein genetic 1 1 1 Negative Genetic
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
MIR1 YJR077C Mitochondrial phosphate carrier physical 1 1 1 Affinity Capture-MS
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis physical 1 1 1 Affinity Capture-MS
RAD51 YER095W Strand exchange protein genetic 1 1 1 Synthetic Lethality
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Positive Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
RPB8 YOR224C RNA polymerase subunit ABC14.5 physical 1 1 1 Affinity Capture-MS
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A physical 1 1 1 Affinity Capture-MS
PUP3 YER094C Beta 3 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Negative Genetic
PCI8 YIL071C Possible shared subunit of Cop9 signalosome (CSN) and eIF3 genetic 1 1 1 Negative Genetic
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A physical 1 1 1 Affinity Capture-MS
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes genetic 1 1 1 Positive Genetic
SEC21 YNL287W Gamma subunit of coatomer physical 1 1 1 Affinity Capture-MS
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer physical 1 1 1 Affinity Capture-MS
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
BGL2 YGR282C Endo-beta-1,3-glucanase physical 1 1 1 Affinity Capture-MS
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Affinity Capture-MS
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
SMD1 YGR074W Core Sm protein Sm D1 physical 1 1 1 Affinity Capture-MS
SMD2 YLR275W Core Sm protein Sm D2 physical 1 1 1 Affinity Capture-MS
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Positive Genetic
MRPL23 YOR150W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Negative Genetic
SKN1 YGR143W Protein involved in sphingolipid biosynthesis genetic 1 1 1 Positive Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
DTD1 YDL219W D-Tyr-tRNA(Tyr) deacylase physical 1 1 1 Affinity Capture-MS
CMS1 YLR003C Putative subunit of the 90S preribosome processome complex physical 1 1 1 Affinity Capture-MS
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 1 1 1 Negative Genetic
ADH2 YMR303C Glucose-repressible alcohol dehydrogenase II physical 1 1 1 Affinity Capture-MS
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase physical 1 1 1 Affinity Capture-MS
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity physical 1 1 1 Affinity Capture-MS
SAC6 YDR129C Fimbrin, actin-bundling protein physical 1 1 1 Affinity Capture-MS
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
CNB1 YKL190W Calcineurin B physical 1 1 1 Affinity Capture-MS
GSP1 YLR293C Ran GTPase physical 1 1 1 Affinity Capture-MS
ARO4 YBR249C 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase physical 1 1 1 Affinity Capture-MS
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 1 1 1 Affinity Capture-MS
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
PDI1 YCL043C Protein disulfide isomerase physical 1 1 1 Affinity Capture-MS
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Negative Genetic
ATG42 YBR139W Vacuolar serine-type carboxypeptidase genetic 1 1 1 Negative Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
PRO3 YER023W Delta 1-pyrroline-5-carboxylate reductase physical 1 1 1 Affinity Capture-MS
DSS1 YMR287C 3'-5' exoribonuclease physical 1 1 1 Affinity Capture-MS
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
ACS2 YLR153C Acetyl-coA synthetase isoform physical 1 1 1 Affinity Capture-MS
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Affinity Capture-MS
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII physical 1 1 1 Affinity Capture-MS
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Affinity Capture-MS
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
ADD66 YKL206C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
MNP1 YGL068W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
GAL7 YBR018C Galactose-1-phosphate uridyl transferase physical 1 1 1 Affinity Capture-MS
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis physical 1 1 1 Affinity Capture-MS
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation physical 1 1 1 Affinity Capture-MS
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Lethality
MNN9 YPL050C Subunit of Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
NTG1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
ILV2 YMR108W Acetolactate synthase physical 1 1 1 Affinity Capture-MS
MSS116 YDR194C Mitochondrial transcription elongation factor physical 1 1 1 Affinity Capture-MS
NOP53 YPL146C Nucleolar protein physical 1 1 1 Affinity Capture-MS
NDE1 YMR145C Mitochondrial external NADH dehydrogenase physical 1 1 1 Affinity Capture-MS
APA1 YCL050C AP4A phosphorylase physical 1 1 1 Affinity Capture-MS
SAN1 YDR143C Ubiquitin-protein ligase genetic 1 1 1 Positive Genetic
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 1 1 1 Affinity Capture-MS
FUB1 YCR076C Proteasome-binding protein genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Positive Genetic
CIA1 YDR267C Component of cytosolic iron-sulfur protein assembly (CIA) machinery physical 1 1 1 Affinity Capture-MS
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p physical 1 1 1 Affinity Capture-MS
CBP2 YHL038C Required for splicing of the group I intron bI5 of the COB pre-mRNA physical 1 1 1 Affinity Capture-MS
FCF1 YDR339C PINc domain endonuclease physical 1 1 1 Affinity Capture-MS
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
APE3 YBR286W Vacuolar aminopeptidase Y genetic 1 1 1 Negative Genetic
RRP3 YHR065C Protein involved in rRNA processing physical 1 1 1 Affinity Capture-MS
RRP3 YHR065C Protein involved in rRNA processing genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
CRC1 YOR100C Mitochondrial inner membrane carnitine transporter genetic 1 1 1 Negative Genetic
APL4 YPR029C Gamma-adaptin physical 1 1 1 Affinity Capture-MS
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway physical 1 1 1 Affinity Capture-MS
SKA1 YKL023W SKI complex-associated protein physical 1 1 1 Affinity Capture-MS
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Positive Genetic
GDH1 YOR375C NADP(+)-dependent glutamate dehydrogenase physical 1 1 1 Affinity Capture-MS
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Positive Genetic
GDS1 YOR355W Protein involved in histone H4 acetylation at ribosomal protein genes physical 1 1 1 Affinity Capture-MS
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
RPS26B YER131W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Affinity Capture-MS
SKI8 YGL213C Ski complex component and WD-repeat protein physical 1 1 1 Affinity Capture-MS
LDB17 YDL146W Protein involved in the regulation of endocytosis genetic 1 1 1 Negative Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 1 1 1 Negative Genetic
HUA1 YGR268C Cytoplasmic protein containing a zinc finger domain genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
FMP40 YPL222W Mitochondrial AMPylator in the pseudokinase selenoprotein-O family physical 1 1 1 Affinity Capture-MS
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Affinity Capture-MS
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CDC21 YOR074C Thymidylate synthase genetic 1 1 1 Positive Genetic
RPL9B YNL067W Ribosomal 60S subunit protein L9B physical 1 1 1 Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
JIP5 YPR169W Protein required for biogenesis of the large ribosomal subunit physical 1 1 1 Affinity Capture-MS
SAC3 YDR159W mRNA export factor genetic 1 1 1 Positive Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Positive Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL22A YLR061W Ribosomal 60S subunit protein L22A physical 1 1 1 Affinity Capture-MS
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Negative Genetic
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 1 1 1 Negative Genetic
ATG8 YBL078C Ub-like protein genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
FRQ1 YDR373W N-myristoylated calcium-binding protein genetic 1 1 1 Negative Genetic
GCD10 YNL062C Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p physical 1 1 1 Affinity Capture-MS
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Positive Genetic
GAL10 YBR019C UDP-glucose-4-epimerase physical 1 1 1 Affinity Capture-MS
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Negative Genetic
GAP1 YKR039W General amino acid permease genetic 1 1 1 Positive Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
SNL1 YIL016W Ribosome-associated protein physical 1 1 1 Affinity Capture-MS
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA physical 1 1 1 Affinity Capture-MS
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Negative Genetic
GAL1 YBR020W Galactokinase physical 1 1 1 Affinity Capture-MS
FBP26 YJL155C Fructose-2,6-bisphosphatase, required for glucose metabolism physical 1 1 1 Affinity Capture-MS
PET309 YLR067C Specific translational activator for the COX1 mRNA physical 1 1 1 Affinity Capture-MS
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA physical 1 1 1 Affinity Capture-MS
RPL1B YGL135W Ribosomal 60S subunit protein L1B physical 1 1 1 Affinity Capture-MS
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
NIP100 YPL174C Large subunit of the dynactin complex genetic 1 1 1 Negative Genetic
ACF2 YLR144C Intracellular beta-1,3-endoglucanase genetic 1 1 1 Negative Genetic
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I physical 1 1 1 Affinity Capture-MS
ERT1 YBR239C Transcriptional regulator genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B physical 1 1 1 Affinity Capture-MS
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Negative Genetic
DBP6 YNR038W Essential protein involved in ribosome biogenesis genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
CBP1 YJL209W Mitochondrial protein, regulator of COB mRNA stability and translation physical 1 1 1 Affinity Capture-MS
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
ERG28 YER044C Endoplasmic reticulum membrane protein physical 1 1 1 Affinity Capture-MS
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RPL18A YOL120C Ribosomal 60S subunit protein L18A physical 1 1 1 Affinity Capture-MS
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPL7A YGL076C Ribosomal 60S subunit protein L7A physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A physical 1 1 1 Affinity Capture-MS
RPL19B YBL027W Ribosomal 60S subunit protein L19B physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Affinity Capture-MS
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
KIP1 YBL063W Kinesin-related motor protein genetic 1 1 1 Negative Genetic
HBS1 YKR084C GTPase with similarity to translation release factors genetic 1 1 1 Negative Genetic
RPL16B YNL069C Ribosomal 60S subunit protein L16B physical 1 1 1 Affinity Capture-MS
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
HLR1 YDR528W Protein involved in regulation of cell wall composition and integrity genetic 1 1 1 Negative Genetic
PSY3 YLR376C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 Affinity Capture-MS
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 1 1 1 Negative Genetic
MRPL11 YDL202W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
PBP4 YDL053C Pbp1p binding protein physical 1 1 1 Affinity Capture-MS
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Positive Genetic
FCY21 YER060W Putative purine-cytosine permease physical 1 1 1 Affinity Capture-MS
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
RRP15 YPR143W Nucleolar protein physical 1 1 1 Affinity Capture-MS
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase physical 1 1 1 Affinity Capture-MS
RPP1A YDL081C Ribosomal stalk protein P1 alpha physical 1 1 1 Affinity Capture-MS
RPL37A YLR185W Ribosomal 60S subunit protein L37A genetic 1 1 1 Positive Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Positive Genetic
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
CSH1 YBR161W Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
MRPL22 YNL177C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 1 1 1 Affinity Capture-MS
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
NVJ3 YDR179W-A Protein with a potential role in tethering ER and vacuoles genetic 1 1 1 Positive Genetic
RRG8 YPR116W Protein of unknown function physical 1 1 1 Affinity Capture-MS
RRG1 YDR065W Protein of unknown function physical 1 1 1 Affinity Capture-MS
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Positive Genetic
RPL24A YGL031C Ribosomal 60S subunit protein L24A physical 1 1 1 Affinity Capture-MS
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Negative Genetic
SDD3 YOL098C Putative metalloprotease genetic 1 1 1 Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes physical 1 1 1 Affinity Capture-MS
RPL4B YDR012W Ribosomal 60S subunit protein L4B physical 1 1 1 Affinity Capture-MS
RPL13B YMR142C Ribosomal 60S subunit protein L13B physical 1 1 1 Affinity Capture-MS
RPL7B YPL198W Ribosomal 60S subunit protein L7B physical 1 1 1 Affinity Capture-MS
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein physical 1 1 1 Affinity Capture-MS
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
UTP11 YKL099C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
UTP23 YOR004W Component of the small subunit processome physical 1 1 1 Affinity Capture-MS
SSF2 YDR312W Protein required for ribosomal large subunit maturation physical 1 1 1 Affinity Capture-MS
YBL028C YBL028C Protein of unknown function that may interact with ribosomes physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone physical 1 1 1 Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
URA1 YKL216W Dihydroorotate dehydrogenase physical 1 1 1 Affinity Capture-MS
URA7 YBL039C Major CTP synthase isozyme (see also URA8) physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Affinity Capture-MS
TUB2 YFL037W Beta-tubulin physical 1 1 1 Affinity Capture-MS
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 1 1 1 Affinity Capture-MS
TIF2 YJL138C Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
YHR020W YHR020W Prolyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor physical 1 1 1 Affinity Capture-MS
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
SRP14 YDL092W Signal recognition particle (SRP) subunit physical 1 1 1 Affinity Capture-MS
SRP21 YKL122C Subunit of the signal recognition particle (SRP) physical 1 1 1 Affinity Capture-MS
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Affinity Capture-MS
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex physical 1 1 1 Affinity Capture-MS
TRP2 YER090W Anthranilate synthase physical 1 1 1 Affinity Capture-MS
SUV3 YPL029W ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
YAT2 YER024W Carnitine acetyltransferase physical 1 1 1 Affinity Capture-MS
TUB1 YML085C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
TUB3 YML124C Alpha-tubulin physical 1 1 1 Affinity Capture-MS
UFD4 YKL010C Ubiquitin-protein ligase (E3) physical 1 1 1 Affinity Capture-MS
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting physical 1 1 1 Affinity Capture-MS
TMA19 YKL056C Protein that associates with ribosomes physical 1 1 1 Affinity Capture-MS
TRI1 YMR233W Non-essential sumoylated protein of unknown function physical 1 1 1 Affinity Capture-MS
YDR514C YDR514C Protein of unknown function that localizes to mitochondria physical 1 1 1 Affinity Capture-MS
YIL161W YIL161W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
YPR089W YPR089W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YPR089W YPR089W Protein of unknown function genetic 1 1 1 Negative Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-Western
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Positive Genetic
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
URB1 YKL014C Protein required for the normal accumulation of 25S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
UTP20 YBL004W Component of the small-subunit (SSU) processome physical 1 1 1 Affinity Capture-MS
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Positive Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Positive Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Positive Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Positive Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Positive Genetic
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex genetic 1 1 1 Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
TSR3 YOR006C Protein required for 20S pre-rRNA processing genetic 1 1 1 Positive Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
YBR016W YBR016W Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Negative Genetic
YBR225W YBR225W Putative protein of unknown function genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
TAD1 YGL243W tRNA-specific adenosine deaminase genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Negative Genetic
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
TPO5 YKL174C Protein involved in excretion of putrescine and spermidine genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
YLR108C YLR108C Protein of unknown function genetic 1 1 1 Negative Genetic
YPS3 YLR121C Aspartic protease genetic 1 1 1 Negative Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Negative Genetic
YET2 YMR040W Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
TVS1 YCR061W Protein of unknown function genetic 1 1 1 Negative Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRM3 YDL112W 2'-O-ribose methyltransferase genetic 1 1 1 Negative Genetic
YPR1 YDR368W NADPH-dependent aldo-keto reductase genetic 1 1 1 Negative Genetic
YGL036W YGL036W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS73 YGL104C Mitochondrial protein genetic 1 1 1 Negative Genetic
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Negative Genetic
YGR283C YGR283C Putative methyltransferase genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
YKL063C YKL063C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKR011C YKR011C Protein of unknown function genetic 1 1 1 Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
YMR244W YMR244W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YNL140C YNL140C Protein of unknown function genetic 1 1 1 Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Negative Genetic
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 1 1 1 Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL17B YJL177W Ribosomal 60S subunit protein L17B physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
RPL35A YDL191W Ribosomal 60S subunit protein L35A genetic 1 1 1 Positive Genetic
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Affinity Capture-MS
RPL33B YOR234C Ribosomal 60S subunit protein L33B physical 1 1 1 Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
RPP2A YOL039W Ribosomal protein P2 alpha physical 1 1 1 Affinity Capture-MS
IPT1 YDR072C Inositolphosphotransferase genetic 1 1 1 Positive Genetic
HEM1 YDR232W 5-aminolevulinate synthase physical 1 1 1 Affinity Capture-MS
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
RCM1 YNL022C rRNA m5C methyltransferase physical 1 1 1 Affinity Capture-MS
RGD3 YHR182W GTPase activating protein (GAP) for Rho3p, involved in cell polarity g genetic 1 1 1 Negative Genetic
DIA1 YMR316W Protein of unknown function genetic 1 1 1 Negative Genetic
IRC4 YDR540C Protein similar to bacterial secreted DfsB proteins genetic 1 1 1 Negative Genetic
RPS18B YML026C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
MRPL49 YJL096W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL14A YKL006W Ribosomal 60S subunit protein L14A physical 1 1 1 Affinity Capture-MS
RPL2B YIL018W Ribosomal 60S subunit protein L2B physical 1 1 1 Affinity Capture-MS
DNF2 YDR093W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
RPP1B YDL130W Ribosomal protein P1 beta physical 1 1 1 Affinity Capture-MS
RPL31B YLR406C Ribosomal 60S subunit protein L31B physical 1 1 1 Affinity Capture-MS
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA physical 1 1 1 Affinity Capture-MS
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 1 1 1 Negative Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 1 1 1 Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
DSC3 YOR223W Subunit of the DSC ubiquitin ligase complex genetic 1 1 1 Negative Genetic
GRX2 YDR513W Cytoplasmic glutaredoxin physical 1 1 1 Affinity Capture-MS
DLD1 YDL174C Major mitochondrial D-lactate dehydrogenase genetic 1 1 1 Positive Genetic
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone physical 1 1 1 Affinity Capture-MS
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex physical 1 1 1 Affinity Capture-MS
RPS25A YGR027C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Positive Genetic
REX4 YOL080C Putative RNA exonuclease physical 1 1 1 Affinity Capture-MS
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MRPL31 YKL138C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MIX23 YBL107C Mitochondrial intermembrane space protein of unknown function genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic
MAL31 YBR298C Maltose permease genetic 1 1 1 Negative Genetic
MAL33 YBR297W MAL-activator protein genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
HMX1 YLR205C ER localized heme oxygenase genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Positive Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B physical 1 1 1 Affinity Capture-MS
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Positive Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 1 1 1 Negative Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Negative Genetic
MPM1 YJL066C Mitochondrial intermembrane space protein of unknown function physical 1 1 1 Affinity Capture-MS
LEU2 YCL018W Beta-isopropylmalate dehydrogenase (IMDH) physical 1 1 1 Affinity Capture-MS
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ERJ5 YFR041C Type I membrane protein with a J domain physical 1 1 1 Affinity Capture-MS
ECM32 YER176W DNA dependent ATPase/DNA helicase physical 1 1 1 Affinity Capture-MS
CBT1 YKL208W Protein involved in 5' RNA end processing physical 1 1 1 Affinity Capture-MS
PET54 YGR222W Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
RRG9 YNL213C Protein of unknown function physical 1 1 1 Affinity Capture-MS
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Positive Genetic
SDH8 YBR269C Protein required for assembly of succinate dehydrogenase genetic 1 1 1 Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
RPS28A YOR167C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Positive Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Positive Genetic
IRC10 YOL015W Protein of unknown function genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Positive Genetic
HPM1 YIL110W AdoMet-dependent methyltransferase genetic 1 1 1 Positive Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
PES4 YFR023W Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation genetic 1 1 1 Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Positive Genetic
PTH4 YOL114C Protein similar to the human peptidyl-tRNA hydrolase gene ICT1 genetic 1 1 1 Negative Genetic