GET2 |
YER083C |
Subunit of the GET complex |
genetic |
10 |
3 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
10 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
9 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
9 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
9 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
8 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
8 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
8 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
7 |
2 |
6 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
7 |
2 |
5 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
7 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERV15 |
YBR210W |
Protein involved in export of proteins from the endoplasmic reticulum |
genetic |
7 |
4 |
4 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic, Dosage Rescue, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic |
PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
GRH1 |
YDR517W |
Acetylated cis-Golgi protein, homolog of human GRASP65 |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
6 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
6 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
5 |
3 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GOT1 |
YMR292W |
Homodimeric protein that is packaged into COPII vesicles |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RCE1 |
YMR274C |
Type II CAAX prenyl protease |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
4 |
2 |
3 |
Positive Genetic, Phenotypic Suppression, Phenotypic Suppression, Positive Genetic |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
4 |
2 |
3 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NHA1 |
YLR138W |
Na+/H+ antiporter |
physical |
4 |
3 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, PCA |
NHA1 |
YLR138W |
Na+/H+ antiporter |
genetic |
3 |
2 |
3 |
Phenotypic Suppression, Dosage Rescue, Dosage Rescue |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Enhancement, Negative Genetic |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Phenotypic Suppression, Phenotypic Suppression |
ELO3 |
YLR372W |
Elongase |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
3 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Positive Genetic |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
EMP24 |
YGL200C |
Component of the p24 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
UBP1 |
YDL122W |
Ubiquitin-specific protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MTC6 |
YHR151C |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
BOP2 |
YLR267W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRS31 |
YDR472W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS3 |
YDR495C |
Component of CORVET membrane tethering complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MTC2 |
YKL098W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEP12 |
YOR036W |
Target membrane receptor (t-SNARE) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
QDR2 |
YIL121W |
Plasma membrane transporter of the major facilitator superfamily |
physical |
2 |
2 |
1 |
PCA, Affinity Capture-Western |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
EMI2 |
YDR516C |
Hexokinase expressed during growth with low glucose levels |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VRG4 |
YGL225W |
Golgi GDP-mannose transporter |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IRC21 |
YMR073C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
PHO80 |
YOL001W |
Cyclin |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MRS6 |
YOR370C |
Rab escort protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
APS1 |
YLR170C |
Small subunit of the clathrin-associated adaptor complex AP-1 |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
EMP65 |
YER140W |
Integral membrane protein of the ER |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AXL2 |
YIL140W |
Integral plasma membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ECM2 |
YBR065C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEX1 |
YOR112W |
Component of nuclear aminoacylation-dependent tRNA export pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCA1 |
YER168C |
ATP (CTP):tRNA-specific tRNA nucleotidyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Co-fractionation |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM30 |
YLR436C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
DSL1 |
YNL258C |
Peripheral membrane protein needed for Golgi-to-ER retrograde traffic |
genetic |
1 |
1 |
1 |
Dosage Rescue |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELO3 |
YLR372W |
Elongase |
physical |
1 |
1 |
1 |
PCA |
BUD8 |
YLR353W |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHS3 |
YBR023C |
Chitin synthase III |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Positive Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
physical |
1 |
1 |
1 |
Co-purification |
RUD3 |
YOR216C |
Golgi matrix protein |
physical |
1 |
1 |
1 |
Co-localization |
GTT1 |
YIR038C |
ER associated glutathione S-transferase |
physical |
1 |
1 |
1 |
Two-hybrid |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
PCA |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
EXP1 |
YDL121C |
A cargo receptor protein for Pma1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOK1 |
YJL093C |
Outward-rectifier potassium channel of the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TOK1 |
YJL093C |
Outward-rectifier potassium channel of the plasma membrane |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TRK1 |
YJL129C |
Component of the Trk1p-Trk2p potassium transport system |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TRK1 |
YJL129C |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC3 |
YER008C |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS33 |
YOR115C |
Core component of TRAPP complexes I, II and IV |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIF1 |
YNL263C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Positive Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR097W |
YPR097W |
Protein that contains a PX domain and binds phosphoinositides |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HER2 |
YMR293C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Negative Genetic |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
LDH1 |
YBR204C |
Serine hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCD4 |
YKL165C |
Protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
YUR1 |
YJL139C |
Mannosyltransferase involved in protein N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
GTA1 |
YEL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT14 |
YPL175W |
UDP-glycosyltransferase subunit of the GPI-GnT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC13 |
YLR208W |
Structural component of 3 complexes |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
GNA1 |
YFL017C |
Glucosamine-6-phosphate acetyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
USV1 |
YPL230W |
Putative transcription factor containing a C2H2 zinc finger |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP25 |
YIL091C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCS4 |
YLR272C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP2 |
YNL088W |
Topoisomerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI18 |
YBR004C |
Functional ortholog of human PIG-V |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC53 |
YFL045C |
Phosphomannomutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDB7 |
YBL006C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEF1 |
YBL066C |
Putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL32 |
YCR003W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCR016W |
YCR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
genetic |
1 |
1 |
1 |
Negative Genetic |
SND1 |
YDR186C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK10 |
YEL053C |
Non-catalytic subunit of the NatC N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER039C-A |
YER039C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRX4 |
YER174C |
Glutathione-dependent oxidoreductase and glutathione S-transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER084W |
YER084W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC19 |
YFR011C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMO1 |
YKL044W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSC3 |
YLR219W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAY24 |
YPR153W |
Peripheral ER membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSP1 |
YHR184W |
Protein involved in the control of meiotic nuclear division |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP51 |
YIL002C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCE101 |
YJL205C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET5 |
YJR137C |
Sulfite reductase beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX17 |
YNL214W |
Membrane peroxin of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
JJJ1 |
YNL227C |
Co-chaperone that stimulates the ATPase activity of Ssa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR032W-A |
YOR032W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMT2 |
YPL224C |
Putative metal transporter involved in mitochondrial iron accumulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL51 |
YPR100W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RAD17 |
YOR368W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TEL1 |
YBL088C |
Protein kinase primarily involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Dosage Rescue |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC7 |
YDR170C |
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPL245W |
YPL245W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRG1 |
YHR209W |
S-AdoMet-dependent methyltransferase involved in lipid homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNF1 |
YER166W |
Aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHS7 |
YHR142W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX11 |
YPL132W |
Protein required for delivery of copper to Cox1p |
physical |
1 |
1 |
1 |
PCA |
AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG11 |
YNL048W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CNE1 |
YAL058W |
Calnexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |