Standard name Systematic name Name description Description
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope Myosin-like protein associated with the nuclear envelope; nuclear basket protein that connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length; MLP2 has a paralog, MLP1, that arose from the whole genome duplication
Visualize the interactome of MLP2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.610 NaN 0.836
Nuc Periphery 0.486 NaN 0.231
Nucleolus 0.219 NaN NaN
Nucleus 0.055 NaN 0.164
Vac/Vac Memb 0.151 NaN 0.060

GFP localization & abundance

GFP localization GFP abundance
nuclear periphery 2770

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MLP2 1 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 8 3 6 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 7 2 5 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 7 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 5 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 5 2 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 5 2 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 5 2 4 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 5 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Negative Genetic
CMD1 YBR109C Calmodulin physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
IST3 YIR005W Component of the U2 snRNP genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SAC3 YDR159W mRNA export factor physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 3 2 2 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
ESC1 YMR219W Protein involved in telomeric silencing physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Co-localization
BUD13 YGL174W Subunit of the RES complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KAP95 YLR347C Karyopherin beta physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 2 2 2 Dosage Rescue, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPC98 YNL126W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
PRP28 YDR243C Pre-mRNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 2 1 2 Negative Genetic, Negative Genetic
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 2 1 2 Positive Genetic, Positive Genetic
CNM67 YNL225C Component of the spindle pole body outer plaque physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BBP1 YPL255W Protein required for the spindle pole body (SPB) duplication physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Negative Genetic, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 2 2 1 Phenotypic Enhancement, Dosage Growth Defect
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 2 2 1 Negative Genetic, Positive Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
TMS1 YDR105C Vacuolar membrane protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Negative Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
CTF3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Positive Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
ADH1 YOL086C Alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
KAP123 YER110C Karyopherin beta physical 1 1 1 Affinity Capture-MS
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family physical 1 1 1 Affinity Capture-MS
LSM5 YER146W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
HPR1 YDR138W Subunit of THO/TREX complexes physical 1 1 1 Affinity Capture-Western
HPR1 YDR138W Subunit of THO/TREX complexes genetic 1 1 1 Synthetic Rescue
MFT1 YML062C Subunit of the THO complex physical 1 1 1 Affinity Capture-MS
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-MS
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 1 1 1 Affinity Capture-MS
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
CDC10 YCR002C Component of the septin ring, required for cytokinesis physical 1 1 1 Affinity Capture-MS
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Affinity Capture-MS
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Affinity Capture-MS
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Affinity Capture-MS
ENO1 YGR254W Enolase I, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) physical 1 1 1 Affinity Capture-MS
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Synthetic Growth Defect
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
KEL1 YHR158C Protein required for proper cell fusion and cell morphology physical 1 1 1 Affinity Capture-MS
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Synthetic Rescue
HTZ1 YOL012C Histone variant H2AZ physical 1 1 1 Affinity Capture-MS
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 1 1 1 Affinity Capture-MS
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex physical 1 1 1 Affinity Capture-MS
BUD21 YOR078W Component of small ribosomal subunit (SSU) processosome physical 1 1 1 Affinity Capture-MS
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 Affinity Capture-MS
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Positive Genetic
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis physical 1 1 1 Affinity Capture-MS
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
ACO1 YLR304C Aconitase genetic 1 1 1 Negative Genetic
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p physical 1 1 1 Affinity Capture-MS
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export physical 1 1 1 Affinity Capture-MS
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis physical 1 1 1 Affinity Capture-MS
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
TEP1 YNL128W PTEN homolog with no demonstrated inositol lipid phosphatase activity physical 1 1 1 Affinity Capture-MS
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) physical 1 1 1 Affinity Capture-Western
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Synthetic Rescue
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Synthetic Rescue
NOC4 YPR144C Nucleolar protein physical 1 1 1 Affinity Capture-MS
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs physical 1 1 1 Two-hybrid
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
RRP17 YDR412W 5' exoribonuclease required for 5' end processing of pre-60S rRNA physical 1 1 1 Affinity Capture-MS
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex physical 1 1 1 Affinity Capture-MS
TUB4 YLR212C Gamma-tubulin physical 1 1 1 Affinity Capture-MS
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein physical 1 1 1 Affinity Capture-MS
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein genetic 1 1 1 Synthetic Rescue
NBP1 YLR457C Spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
MPS1 YDL028C Dual-specificity kinase physical 1 1 1 Biochemical Activity
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
MTR2 YKL186C mRNA transport regulator physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein physical 1 1 1 Affinity Capture-MS
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family physical 1 1 1 Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 1 1 1 Affinity Capture-MS
THP2 YHR167W Subunit of the THO and TREX complexes physical 1 1 1 Affinity Capture-MS
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Synthetic Growth Defect
THP1 YOL072W Nuclear pore-associated protein physical 1 1 1 Affinity Capture-MS
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component physical 1 1 1 Affinity Capture-MS
NOP53 YPL146C Nucleolar protein physical 1 1 1 Affinity Capture-MS
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
SOF1 YLL011W Protein required for biogenesis of 40S (small) ribosomal subunit physical 1 1 1 Affinity Capture-MS
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 1 1 1 Affinity Capture-MS
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs physical 1 1 1 Affinity Capture-MS
PRE4 YFR050C Beta 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 1 1 1 Affinity Capture-MS
RSA3 YLR221C Protein with a likely role in ribosomal maturation physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone physical 1 1 1 Affinity Capture-MS
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
MSC3 YLR219W Protein of unknown function physical 1 1 1 Affinity Capture-MS
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
SMD1 YGR074W Core Sm protein Sm D1 physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 Affinity Capture-MS
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 1 1 1 Affinity Capture-MS
PRE7 YBL041W Beta 6 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
NOP16 YER002W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Positive Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
SLX9 YGR081C Protein required for pre-rRNA processing physical 1 1 1 Affinity Capture-MS
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex physical 1 1 1 Affinity Capture-MS
PRE3 YJL001W Beta 1 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Affinity Capture-MS
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
PBP4 YDL053C Pbp1p binding protein physical 1 1 1 Affinity Capture-MS
MNP1 YGL068W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPO26 YPR187W RNA polymerase subunit ABC23 physical 1 1 1 Affinity Capture-MS
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II physical 1 1 1 Affinity Capture-MS
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
SUB1 YMR039C Transcriptional regulator physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
NUP49 YGL172W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
MPP10 YJR002W Component of the SSU processome and 90S preribosome physical 1 1 1 Affinity Capture-MS
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor physical 1 1 1 Affinity Capture-MS
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Affinity Capture-MS
PUP3 YER094C Beta 3 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
SNU13 YEL026W RNA binding protein physical 1 1 1 Affinity Capture-MS
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex physical 1 1 1 Affinity Capture-MS
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
YHM2 YMR241W Citrate and oxoglutarate carrier protein physical 1 1 1 Affinity Capture-MS
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
NBA1 YOL070C Protein involved in axial bud site selection physical 1 1 1 Affinity Capture-MS
NSR1 YGR159C Nucleolin, nucleolar protein that binds nuclear localization sequences physical 1 1 1 Affinity Capture-MS
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
YHR127W YHR127W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YLR146W-A YLR146W-A Protein of unknown function physical 1 1 1 Affinity Capture-MS
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
NHP6A YPR052C High-mobility group (HMG) protein physical 1 1 1 Affinity Capture-MS
RBL2 YOR265W Protein involved in microtubule morphogenesis physical 1 1 1 Affinity Capture-MS
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
PRE8 YML092C Alpha 2 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs physical 1 1 1 Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
RPL2B YIL018W Ribosomal 60S subunit protein L2B physical 1 1 1 Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 1 1 1 Affinity Capture-MS
TDH1 YJL052W Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 physical 1 1 1 Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
TMA19 YKL056C Protein that associates with ribosomes physical 1 1 1 Affinity Capture-MS
NNK1 YKL171W Protein kinase physical 1 1 1 Affinity Capture-MS
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
PDR11 YIL013C ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SEG2 YKL105C Eisosome component physical 1 1 1 Affinity Capture-MS
YPR158C-C YPR158C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL7B YPL198W Ribosomal 60S subunit protein L7B physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TRM732 YMR259C Protein involved in 2'-O-methylation of C32 of substrate tRNAs physical 1 1 1 Affinity Capture-MS
TAO3 YIL129C Component of the RAM signaling network physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Affinity Capture-MS
RPL27B YDR471W Ribosomal 60S subunit protein L27B physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase physical 1 1 1 Affinity Capture-MS
WTM1 YOR230W Transcriptional modulator physical 1 1 1 Affinity Capture-MS
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 1 1 1 Affinity Capture-MS
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding physical 1 1 1 Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 1 1 1 Affinity Capture-MS
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) physical 1 1 1 Affinity Capture-MS
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Synthetic Lethality
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Synthetic Lethality
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Synthetic Rescue
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
UGA4 YDL210W GABA (gamma-aminobutyrate) permease genetic 1 1 1 Positive Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Synthetic Rescue
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Phenotypic Enhancement
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Synthetic Growth Defect
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Positive Genetic
RPL20A YMR242C Ribosomal 60S subunit protein L20A genetic 1 1 1 Positive Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 1 1 1 Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Negative Genetic
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
RNH1 YMR234W Ribonuclease H1 genetic 1 1 1 Phenotypic Suppression
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
UBP12 YJL197W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
GFD1 YMR255W Coiled-coiled protein of unknown function physical 1 1 1 Affinity Capture-MS
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
DET1 YDR051C Acid phosphatase physical 1 1 1 Affinity Capture-MS
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) physical 1 1 1 Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Affinity Capture-MS
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint physical 1 1 1 Co-localization
HRB1 YNL004W Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-MS
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase physical 1 1 1 Affinity Capture-MS
BPT1 YLL015W ABC type transmembrane transporter of MRP/CFTR family physical 1 1 1 Affinity Capture-MS
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
KAR1 YNL188W Protein involved in karyogamy and spindle pole body duplication physical 1 1 1 Affinity Capture-MS
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus physical 1 1 1 Affinity Capture-MS
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization genetic 1 1 1 Negative Genetic
ACP1 YKL192C Mitochondrial matrix acyl carrier protein physical 1 1 1 Affinity Capture-MS
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Positive Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Negative Genetic
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Phenotypic Enhancement
MET3 YJR010W ATP sulfurylase physical 1 1 1 Affinity Capture-MS
EFG1 YGR271C-A Ribosome biogenesis factor required for maturation of 18S rRNA physical 1 1 1 Affinity Capture-MS
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER physical 1 1 1 Affinity Capture-MS
CMI7 YIL002W-A Putative mitochondrial protein of unknown function physical 1 1 1 Affinity Capture-MS
MIM2 YLR099W-A Mitochondrial protein required for outer membrane protein import physical 1 1 1 Affinity Capture-MS
ALG11 YNL048W Alpha-1,2-mannosyltransferase physical 1 1 1 Affinity Capture-MS
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Positive Genetic