| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
physical |
16 |
3 |
16 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
| TPD3 |
YAL016W |
Regulatory subunit A of the heterotrimeric PP2A complex |
physical |
14 |
2 |
12 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| PPH22 |
YDL188C |
Catalytic subunit of protein phosphatase 2A, PP2A |
physical |
13 |
3 |
12 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
| ZDS2 |
YML109W |
Protein with a role in regulating Swe1p-dependent polarized growth |
physical |
11 |
3 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
physical |
9 |
2 |
9 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| NET1 |
YJL076W |
Core subunit of the RENT complex |
genetic |
7 |
2 |
6 |
Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression |
| IGO1 |
YNL157W |
Protein required for initiation of G0 program |
genetic |
6 |
3 |
6 |
Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression |
| IGO2 |
YHR132W-A |
Protein required for initiation of G0 program |
genetic |
6 |
3 |
6 |
Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
6 |
4 |
3 |
Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Dosage Rescue, Synthetic Growth Defect, Synthetic Rescue |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
5 |
4 |
5 |
Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression, Negative Genetic, Phenotypic Enhancement |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
5 |
3 |
5 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Dosage Lethality, Synthetic Rescue |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
5 |
4 |
3 |
Dosage Lethality, Synthetic Lethality, Dosage Lethality, Dosage Rescue, Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
4 |
3 |
4 |
Synthetic Growth Defect, Negative Genetic, Dosage Growth Defect, Negative Genetic |
| RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
4 |
2 |
4 |
Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression |
| ZDS2 |
YML109W |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
4 |
3 |
3 |
Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Growth Defect |
| IGO1 |
YNL157W |
Protein required for initiation of G0 program |
physical |
4 |
2 |
3 |
PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| CDC16 |
YKL022C |
Subunit of the anaphase-promoting complex/cyclosome (APC/C) |
genetic |
4 |
2 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression |
| NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
4 |
4 |
2 |
Two-hybrid, Biochemical Activity, Affinity Capture-Western, Reconstituted Complex |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
3 |
3 |
3 |
Synthetic Rescue, Phenotypic Suppression, Dosage Lethality |
| PPH22 |
YDL188C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
3 |
3 |
3 |
Synthetic Rescue, Synthetic Growth Defect, Dosage Rescue |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Negative Genetic, Synthetic Rescue |
| BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
3 |
2 |
3 |
Negative Genetic, Dosage Growth Defect, Negative Genetic |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| SGO1 |
YOR073W |
Component of the spindle checkpoint |
genetic |
3 |
2 |
3 |
Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Synthetic Rescue |
| GRR1 |
YJR090C |
F-box protein component of an SCF ubiquitin-ligase complex |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Dosage Rescue |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement |
| HHF1 |
YBR009C |
Histone H4 |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
3 |
3 |
1 |
Synthetic Lethality, Dosage Rescue, Phenotypic Suppression |
| CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
genetic |
3 |
2 |
1 |
Dosage Lethality, Dosage Lethality, Synthetic Rescue |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Biochemical Activity |
| MYO5 |
YMR109W |
One of two type I myosin motors |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Dosage Rescue |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
2 |
2 |
2 |
Dosage Growth Defect, Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Biochemical Activity |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Dosage Growth Defect |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Growth Defect |
| RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| GIP3 |
YPL137C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| DMA1 |
YHR115C |
Ubiquitin-protein ligase (E3) |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Lethality |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Rescue |
| PDS1 |
YDR113C |
Securin |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Lethality |
| CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
2 |
2 |
2 |
Dosage Lethality, Synthetic Lethality |
| SPO11 |
YHL022C |
Meiosis-specific protein required for meiotic recombination |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Synthetic Rescue |
| ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Rescue |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Rescue |
| CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RTS3 |
YGR161C |
Putative component of the protein phosphatase type 2A complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PPG1 |
YNR032W |
Serine protein phosphatase involved in formation of FAR complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MBP1 |
YDL056W |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
| CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Dosage Lethality |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Synthetic Lethality |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| AMN1 |
YBR158W |
Modulator of cell separation and mitotic exit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| AXL2 |
YIL140W |
Integral plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ATG14 |
YBR128C |
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
physical |
1 |
1 |
1 |
Two-hybrid |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| BOI2 |
YER114C |
Protein involved in polar growth |
physical |
1 |
1 |
1 |
Two-hybrid |
| BOI2 |
YER114C |
Protein involved in polar growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHR033W |
YHR033W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YRR1 |
YOR162C |
Zn2-Cys6 zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Protein-RNA |
| YSC84 |
YHR016C |
Actin-binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| MYO3 |
YKL129C |
One of two type I myosins |
physical |
1 |
1 |
1 |
Two-hybrid |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
| PEX13 |
YLR191W |
Peroxisomal importomer complex component |
physical |
1 |
1 |
1 |
Two-hybrid |
| PIN3 |
YPR154W |
Negative regulator of actin nucleation-promoting factor activity |
physical |
1 |
1 |
1 |
Two-hybrid |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PPG1 |
YNR032W |
Serine protein phosphatase involved in formation of FAR complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCN2 |
YDR283C |
Protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| GIS1 |
YDR096W |
Histone demethylase and transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IGO2 |
YHR132W-A |
Protein required for initiation of G0 program |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TGL1 |
YKL140W |
Steryl ester hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TOP2 |
YNL088W |
Topoisomerase II |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHS1 |
YDR247W |
Cytoplasmic serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSL1 |
YML100W |
Large subunit of trehalose 6-phosphate synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSK1 |
YAL017W |
PAS domain-containing serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOG2 |
YHR043C |
2-deoxyglucose-6-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TWF1 |
YGR080W |
Twinfilin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PIL1 |
YGR086C |
Eisosome core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GUT1 |
YHL032C |
Glycerol kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR1 |
YJR110W |
Phosphatidylinositol 3-phosphate (PI3P) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPO14 |
YKR031C |
Phospholipase D |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YSR3 |
YKR053C |
Dihydrosphingosine 1-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESC1 |
YMR219W |
Protein involved in telomeric silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSK2 |
YOL045W |
PAS-domain containing serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SKM1 |
YOL113W |
Member of the PAK family of serine/threonine protein kinases |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SKS1 |
YPL026C |
Putative serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CQD1 |
YPL109C |
UbiB family mitochondrial protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPQ1 |
YPL179W |
Protein phosphatase that regulates the mating response |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MAM1 |
YER106W |
Monopolin |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SEC3 |
YER008C |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PIG2 |
YIL045W |
Putative type-1 protein phosphatase targeting subunit |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| TGL3 |
YMR313C |
Bifunctional triacylglycerol lipase and LPE acyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| TGL4 |
YKR089C |
Multifunctional lipase/hydrolase/phospholipase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRB6 |
YBR253W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HNT1 |
YDL125C |
Adenosine 5'-monophosphoramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBE2 |
YDR351W |
Protein required for bud growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FDC1 |
YDR539W |
Ferulic acid decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR7 |
YFR008W |
Protein involved in recovery from pheromone-induced cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB6 |
YGR109C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEP1 |
YGR121C |
Ammonium permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCD1 |
YHR003C |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC6 |
YHR151C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAX4 |
YJL083W |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM27 |
YJR106W |
Protein involved in calcium homeostasis and exit from quiescence |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAC1 |
YKL008C |
Ceramide synthase component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP25 |
YLR077W |
Protein required for assembly of respiratory complex III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUN1 |
YLR414C |
Plasma membrane protein with a role in cell wall integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FDO1 |
YMR144W |
Protein involved in directionality of mating type switching |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRM1 |
YNR009W |
Transcriptional co-repressor of MBF-regulated gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SVL3 |
YPL032C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL162C |
YPL162C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCD6 |
YPR129W |
Repressor of translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM1 |
YGR070W |
Guanine nucleotide exchange factor (GEF) for Rho1p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NIT3 |
YLR351C |
Nit protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SPO12 |
YHR152W |
Nucleolar protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| EST2 |
YLR318W |
Reverse transcriptase subunit of the telomerase holoenzyme |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG18 |
YFR021W |
Phosphoinositide binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
Two-hybrid |
| CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BOI1 |
YBL085W |
Protein involved in polar growth, functionally redundant with Boi2p |
physical |
1 |
1 |
1 |
Two-hybrid |
| ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
physical |
1 |
1 |
1 |
Two-hybrid |
| ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CBK1 |
YNL161W |
Serine/threonine protein kinase of the the RAM signaling network |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APA1 |
YCL050C |
AP4A phosphorylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD4 |
YJR092W |
Anillin-like protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCH2 |
YKR027W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APA2 |
YDR530C |
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |