CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
18 |
5 |
13 |
Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Co-purification, Two-hybrid, Two-hybrid, Affinity Capture-Western |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
physical |
17 |
5 |
14 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, PCA, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-purification |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
16 |
4 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Two-hybrid, Two-hybrid |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
12 |
6 |
11 |
Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
9 |
2 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Affinity Capture-MS |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
physical |
8 |
1 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
UTP22 |
YGR090W |
Component of the small-subunit processome |
physical |
7 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
physical |
7 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Biochemical Activity |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
6 |
2 |
6 |
Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HOT1 |
YMR172W |
Transcription factor for glycerol biosynthetic genes |
physical |
6 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
physical |
5 |
2 |
3 |
Biochemical Activity, Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Biochemical Activity |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Biochemical Activity, Two-hybrid, Affinity Capture-MS |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity |
RRP7 |
YCL031C |
Essential protein involved in rRNA processing and ribosome biogenesis |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
HHF1 |
YBR009C |
Histone H4 |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Biochemical Activity |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
physical |
4 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
3 |
2 |
3 |
Dosage Rescue, Negative Genetic, Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity |
HHT1 |
YBR010W |
Histone H3 |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Biochemical Activity, Biochemical Activity |
HHF2 |
YNL030W |
Histone H4 |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
CAB3 |
YKL088W |
Subunit of PPCDC and CoA-SPC complexes involved in CoA biosynthesis |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
physical |
3 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity |
RRP36 |
YOR287C |
Component of 90S preribosomes |
physical |
3 |
3 |
2 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western |
UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Two-hybrid, Two-hybrid |
SVF1 |
YDR346C |
Protein with a potential role in cell survival pathways |
physical |
3 |
2 |
2 |
Biochemical Activity, Affinity Capture-Western, Biochemical Activity |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
physical |
3 |
2 |
1 |
Reconstituted Complex, Reconstituted Complex, Biochemical Activity |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Biochemical Activity |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Biochemical Activity |
NRG1 |
YDR043C |
Transcriptional repressor |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Biochemical Activity |
NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Biochemical Activity |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Biochemical Activity |
RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
YCF1 |
YDR135C |
Vacuolar glutathione S-conjugate transporter |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-Western |
IFH1 |
YLR223C |
Coactivator, regulates transcription of ribosomal protein (RP) genes |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
CDC73 |
YLR418C |
Component of the Paf1p complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HTB2 |
YBL002W |
Histone H2B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
RRP15 |
YPR143W |
Nucleolar protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAK1 |
YER129W |
Upstream serine/threonine kinase for the SNF1 complex |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Biochemical Activity |
SPT23 |
YKL020C |
ER membrane protein involved in regulation of OLE1 transcription |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
HCA4 |
YJL033W |
DEAD box RNA helicase |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
PXR1 |
YGR280C |
Essential protein involved in rRNA and snoRNA maturation |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
ATG32 |
YIL146C |
Mitochondrial outer membrane protein required to initiate mitophagy |
physical |
2 |
2 |
1 |
Biochemical Activity, Affinity Capture-Western |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HHT2 |
YNL031C |
Histone H3 |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
HHT1 |
YBR010W |
Histone H3 |
regulation |
1 |
1 |
1 |
qualitative western immunoblotting evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
co-immunoprecipitation evidence |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FKH1 |
YIL131C |
Forkhead family transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLD2 |
YKL108W |
Single-stranded DNA origin-binding and annealing protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDI1 |
YCL043C |
Protein disulfide isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENP2 |
YGR145W |
Component of the SSU |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GDE1 |
YPL110C |
Glycerophosphocholine (GroPCho) phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
WTM2 |
YOR229W |
Transcriptional modulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS73 |
YGL104C |
Mitochondrial protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMR1 |
YHL035C |
Vacuolar membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRL1 |
YJL087C |
tRNA ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP14 |
YKL082C |
Essential protein, constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP4 |
YPL043W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
physical |
1 |
1 |
1 |
Two-hybrid |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Biochemical Activity |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
physical |
1 |
1 |
1 |
Biochemical Activity |
FUN30 |
YAL019W |
Snf2p family member with ATP-dependent chromatin remodeling activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHR131C |
YHR131C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRB2 |
YIL063C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REH1 |
YLR387C |
Cytoplasmic 60S subunit biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOP2 |
YNL088W |
Topoisomerase II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPD2 |
YOL088C |
Member of the protein disulfide isomerase (PDI) family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWC5 |
YBR231C |
Component of the SWR1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMC1 |
YOR052C |
AN1-type zinc finger protein, effector of proteotoxic stress response |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
physical |
1 |
1 |
1 |
Biochemical Activity |
MBR1 |
YKL093W |
Protein involved in mitochondrial functions and stress response |
physical |
1 |
1 |
1 |
Biochemical Activity |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Biochemical Activity |
VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Biochemical Activity |
YJR096W |
YJR096W |
Xylose and arabinose reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
YJR096W |
YJR096W |
Xylose and arabinose reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DDR48 |
YMR173W |
DNA damage-responsive protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
1 |
1 |
1 |
Biochemical Activity |
RNH70 |
YGR276C |
3'-5' exoribonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
physical |
1 |
1 |
1 |
Biochemical Activity |
YLR345W |
YLR345W |
Similar to 6-phosphofructo-2-kinase enzymes |
physical |
1 |
1 |
1 |
Biochemical Activity |
YKR041W |
YKR041W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MIH1 |
YMR036C |
Protein tyrosine phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SGT1 |
YOR057W |
Cochaperone protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MNR2 |
YKL064W |
Vacuolar membrane protein required for magnesium homeostasis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIF1 |
YBR275C |
Protein involved in control of DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOF2 |
YKR010C |
Protein required for rDNA silencing and mitotic rDNA condensation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UAF30 |
YOR295W |
Subunit of UAF (upstream activation factor) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSR2 |
YLR019W |
Putative plasma membrane phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Biochemical Activity |
URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
1 |
1 |
1 |
Biochemical Activity |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
1 |
1 |
1 |
Reconstituted Complex |
TOM20 |
YGR082W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
MIM1 |
YOL026C |
Mitochondrial protein required for outer membrane protein import |
physical |
1 |
1 |
1 |
Biochemical Activity |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Biochemical Activity |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NPL3 |
YDR432W |
RNA-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
DGK1 |
YOR311C |
Diacylglycerol kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
physical |
1 |
1 |
1 |
PCA |
SGD1 |
YLR336C |
Essential nuclear protein |
physical |
1 |
1 |
1 |
Two-hybrid |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
UTP7 |
YER082C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Two-hybrid |
UTP7 |
YER082C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Two-hybrid |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Two-hybrid |
ESF2 |
YNR054C |
Essential nucleolar protein involved in pre-18S rRNA processing |
physical |
1 |
1 |
1 |
Two-hybrid |
IMP3 |
YHR148W |
Component of the SSU processome |
physical |
1 |
1 |
1 |
Two-hybrid |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
physical |
1 |
1 |
1 |
Two-hybrid |
UTP14 |
YML093W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIP1 |
YOR330C |
Mitochondrial DNA polymerase gamma |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL036C |
YBL036C |
Putative non-specific single-domain racemase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB3 |
YML124C |
Alpha-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFT2 |
YBL102W |
Tetra-spanning membrane protein found mostly in the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPS1 |
YLR120C |
Aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
TBS1 |
YBR150C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
MLS1 |
YNL117W |
Malate synthase, enzyme of the glyoxylate cycle |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YGR038C-B |
YGR038C-B |
Retrotransposon TYA Gag and TYB Pol genes |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
GIP2 |
YER054C |
Putative regulatory subunit of protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
YJL070C |
YJL070C |
Putative metallo-dependent hydrolase superfamily protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ICS2 |
YBR157C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPT1 |
YGR123C |
Protein serine/threonine phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX9 |
YDL067C |
Subunit VIIa of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRX14 |
YDR115W |
Putative mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Positive Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRG9 |
YNL213C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
FIT2 |
YOR382W |
Mannoprotein that is incorporated into the cell wall |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOP1 |
YDR141C |
Protein involved in vesicular transport at trans-Golgi network (TGN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBA50 |
YDR527W |
Protein involved in transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR3 |
YGR158C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET112 |
YBL080C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIG1 |
YBR040W |
Integral membrane protein required for efficient mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
TYR1 |
YBR166C |
Prephenate dehydrogenase involved in tyrosine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR298C-A |
YBR298C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP10 |
YDL045W-A |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT5 |
YDL093W |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGT2 |
YDL138W |
Plasma membrane high glucose sensor that regulates glucose transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNF2 |
YDR093W |
Aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP20 |
YDR405W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS26A |
YGL189C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR153W |
YGR153W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
COS6 |
YGR295C |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTG2 |
YHR168W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR210C |
YHR210C |
Putative aldose 1-epimerase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RDH54 |
YBR073W |
DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTC2 |
YBR147W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET12 |
YPL023C |
Protein with MTHFR activity in vitro |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
genetic |
1 |
1 |
1 |
Negative Genetic |
TVP38 |
YKR088C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR012C |
YLR012C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC12 |
YLR306W |
Enzyme that mediates the conjugation of Rub1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR412C-A |
YLR412C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML003W |
YML003W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMP1 |
YMR150C |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMT2 |
YPL224C |
Putative metal transporter involved in mitochondrial iron accumulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLD1 |
YPR109W |
Component of Dsc E3 ligase complex in Golgi and endosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
BDF1 |
YLR399C |
BET family transcriptional regulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CHC1 |
YGL206C |
Clathrin heavy chain |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Negative Genetic |
AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Biochemical Activity |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
CAT8 |
YMR280C |
Zinc cluster transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARR1 |
YPR199C |
Transcriptional activator of the basic leucine zipper (bZIP) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAX4 |
YGR036C |
Dolichyl pyrophosphate (Dol-P-P) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |