Standard name Systematic name Name description Description
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) Phosphatidylethanolamine methyltransferase (PEMT); catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis
Visualize the interactome of CHO2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.182 0.199 0.277
Cort. Patches 0.100 0.169 0.210
Cytoplasm 0.120 0.126 NaN
ER 0.797 0.712 0.747
Bud NaN 0.060 NaN
Golgi NaN NaN 0.092

GFP localization & abundance

GFP localization GFP abundance
ER 1810

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CHO2 5 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_2495 (PE methyltransferase (1-18:1, 2-18:1), ER membrane), r_2489 (PE methyltransferase (1-16:1, 2-16:1), ER membrane), r_2494 (PE methyltransferase (1-18:0, 2-18:1), ER membrane), r_2491 (PE methyltransferase (1-18:1, 2-16:1), ER membrane), r_2493 (PE methyltransferase (1-16:1, 2-18:1), ER membrane), r_2488 (PE methyltransferase (1-16:0, 2-16:1), ER membrane), r_2490 (PE methyltransferase (1-18:0, 2-16:1), ER membrane), r_2492 (PE methyltransferase (1-16:0, 2-18:1), ER membrane)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 11 6 10 Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 8 2 6 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 8 3 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Dosage Rescue, Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 7 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EMC4 YGL231C Member of conserved ER transmembrane complex genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CKI1 YLR133W Choline kinase genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 7 3 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 7 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 7 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 6 2 5 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EMC2 YJR088C Member of conserved ER transmembrane complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CUE1 YMR264W Ubiquitin-binding protein genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CNB1 YKL190W Calcineurin B genetic 5 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 5 2 4 Positive Genetic, Positive Genetic, Synthetic Growth Defect, Positive Genetic, Positive Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 5 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LPL1 YOR059C Phospholipase genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect
STE24 YJR117W Highly conserved zinc metalloprotease genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 5 3 3 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 5 2 3 Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 5 2 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Negative Genetic
YPR063C YPR063C ER-localized protein of unknown function genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR8 YMR029C Protein involved in recovery from arrest in response to pheromone genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YNR021W YNR021W Putative protein of unknown function genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARE1 YCR048W Acyl-CoA:sterol acyltransferase genetic 4 2 3 Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic
YBR287W YBR287W Protein of unknown function genetic 4 2 3 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 4 2 3 Positive Genetic, Dosage Lethality, Dosage Lethality, Positive Genetic
SBH2 YER019C-A Ssh1p-Sss1p-Sbh2p complex component genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
EMC1 YCL045C Member of conserved endoplasmic reticulum membrane complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PCT1 YGR202C Cholinephosphate cytidylyltransferase genetic 4 2 2 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
EMC5 YIL027C Member of conserved ER transmembrane complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IZH1 YDR492W Membrane protein involved in zinc ion homeostasis genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBP1 YDL122W Ubiquitin-specific protease genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 4 1 2 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 4 1 2 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PUB1 YNL016W Poly (A)+ RNA-binding protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CST9 YLR394W SUMO E3 ligase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 3 2 2 Positive Genetic, Positive Genetic, Negative Genetic
HMG2 YLR450W HMG-CoA reductase genetic 3 2 2 Positive Genetic, Positive Genetic, Dosage Growth Defect
ALE1 YOR175C Broad-specificity lysophospholipid acyltransferase genetic 3 2 2 Positive Genetic, Positive Genetic, Synthetic Growth Defect
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
APP1 YNL094W Phosphatidate phosphatase, converts phosphatidate to diacylglycerol genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IZH3 YLR023C Membrane protein involved in zinc ion homeostasis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HRD3 YLR207W ER membrane protein that plays a central role in ERAD genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SOP4 YJL192C ER-membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YDR124W YDR124W Mitochondrial protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PCL6 YER059W Pho85p cyclin of the Pho80p subfamily genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DPC29 YGR021W Putative mitochondrial protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CYB5 YNL111C Cytochrome b5 genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PNS1 YOR161C Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MCD4 YKL165C Protein involved in GPI anchor synthesis genetic 3 3 1 Synthetic Rescue, Dosage Growth Defect, Phenotypic Suppression
CMD1 YBR109C Calmodulin genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 2 2 Negative Genetic, Positive Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 2 2 2 Synthetic Rescue, Negative Genetic
NTE1 YML059C Serine esterase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 2 2 2 Positive Genetic, Synthetic Rescue
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 2 2 Dosage Growth Defect, Negative Genetic
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 2 2 2 Dosage Rescue, Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 2 2 2 Negative Genetic, Phenotypic Suppression
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 2 2 2 Phenotypic Enhancement, Positive Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 2 1 2 Negative Genetic, Negative Genetic
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
ARE2 YNR019W Acyl-CoA:sterol acyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 2 1 2 Negative Genetic, Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 2 1 2 Negative Genetic, Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 2 1 2 Negative Genetic, Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 2 1 2 Negative Genetic, Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
MTW1 YAL034W-A Essential component of the MIND kinetochore complex genetic 2 1 2 Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 2 1 2 Positive Genetic, Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 1 2 Positive Genetic, Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 2 1 2 Negative Genetic, Negative Genetic
SDT1 YGL224C Pyrimidine nucleotidase genetic 2 1 2 Negative Genetic, Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 1 2 Positive Genetic, Positive Genetic
PYC2 YBR218C Pyruvate carboxylase isoform genetic 2 1 2 Negative Genetic, Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
MTC3 YGL226W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly genetic 2 1 2 Negative Genetic, Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 2 1 2 Positive Genetic, Positive Genetic
MUB1 YMR100W MYND domain-containing protein genetic 2 1 2 Positive Genetic, Positive Genetic
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 2 1 2 Positive Genetic, Positive Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 2 1 2 Negative Genetic, Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 2 1 2 Negative Genetic, Negative Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 2 1 2 Negative Genetic, Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 2 1 2 Negative Genetic, Negative Genetic
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 2 1 2 Negative Genetic, Negative Genetic
HRK1 YOR267C Protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 2 1 2 Positive Genetic, Positive Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 2 1 2 Negative Genetic, Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 2 1 2 Negative Genetic, Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 2 1 2 Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 2 1 2 Negative Genetic, Negative Genetic
GTA1 YEL043W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 2 1 2 Positive Genetic, Positive Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 2 1 2 Negative Genetic, Negative Genetic
NPR1 YNL183C Protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 2 1 2 Negative Genetic, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 2 Negative Genetic, Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 2 1 2 Negative Genetic, Negative Genetic
CRG1 YHR209W S-AdoMet-dependent methyltransferase involved in lipid homeostasis genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 2 2 1 Positive Genetic, Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 2 2 1 Negative Genetic, Positive Genetic
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex genetic 2 2 1 Negative Genetic, Positive Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 2 2 1 Negative Genetic, Positive Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 2 2 1 Positive Genetic, Negative Genetic
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 2 1 1 Negative Genetic, Negative Genetic
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p genetic 2 1 1 Positive Genetic, Positive Genetic
BIT61 YJL058C Subunit of TORC2 membrane-associated complex genetic 2 1 1 Negative Genetic, Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
SAY1 YGR263C Sterol deacetylase genetic 2 1 1 Negative Genetic, Negative Genetic
SRP72 YPL210C Core component of the signal recognition particle (SRP) genetic 2 1 1 Negative Genetic, Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 2 1 1 Negative Genetic, Negative Genetic
EXP1 YDL121C A cargo receptor protein for Pma1p genetic 2 1 1 Negative Genetic, Negative Genetic
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 2 1 1 Negative Genetic, Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 2 1 1 Negative Genetic, Negative Genetic
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 2 1 1 Negative Genetic, Negative Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 2 1 1 Negative Genetic, Negative Genetic
GRH1 YDR517W Acetylated cis-Golgi protein, homolog of human GRASP65 genetic 2 1 1 Negative Genetic, Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 2 1 1 Negative Genetic, Negative Genetic
DSL1 YNL258C Peripheral membrane protein needed for Golgi-to-ER retrograde traffic genetic 2 1 1 Negative Genetic, Negative Genetic
RCE1 YMR274C Type II CAAX prenyl protease genetic 2 1 1 Negative Genetic, Negative Genetic
GTB1 YDR221W Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p genetic 2 1 1 Negative Genetic, Negative Genetic
YIP5 YGL161C Protein that interacts with Rab GTPases genetic 2 1 1 Negative Genetic, Negative Genetic
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 2 1 1 Negative Genetic, Negative Genetic
SGM1 YJR134C Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
YIM1 YMR152W Aldehyde reductase genetic 2 1 1 Positive Genetic, Positive Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 2 1 1 Positive Genetic, Positive Genetic
MSC7 YHR039C Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 2 1 1 Positive Genetic, Positive Genetic
NCE102 YPR149W Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane genetic 2 1 1 Positive Genetic, Positive Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 2 1 1 Positive Genetic, Positive Genetic
TGL1 YKL140W Steryl ester hydrolase genetic 2 1 1 Positive Genetic, Positive Genetic
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ genetic 2 1 1 Positive Genetic, Positive Genetic
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 2 1 1 Positive Genetic, Positive Genetic
SLC1 YDL052C 1-acyl-sn-glycerol-3-phosphate acyltransferase genetic 2 1 1 Positive Genetic, Positive Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 2 1 1 Positive Genetic, Positive Genetic
KTR3 YBR205W Putative alpha-1,2-mannosyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
UPC2 YDR213W Sterol regulatory element binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 2 1 1 Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 2 1 1 Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 2 1 1 Positive Genetic, Positive Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 2 1 1 Positive Genetic, Positive Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
PHO80 YOL001W Cyclin genetic 2 1 1 Negative Genetic, Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 2 1 1 Negative Genetic, Negative Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 2 1 1 Negative Genetic, Negative Genetic
SOV1 YMR066W Mitochondrial protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LCB2 YDR062W Component of serine palmitoyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 2 1 1 Negative Genetic, Negative Genetic
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 2 1 1 Negative Genetic, Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 2 1 1 Negative Genetic, Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 2 1 1 Positive Genetic, Positive Genetic
ATX2 YOR079C Golgi membrane protein involved in manganese homeostasis genetic 2 1 1 Positive Genetic, Positive Genetic
ALG8 YOR067C Glucosyl transferase genetic 2 1 1 Positive Genetic, Positive Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
INO4 YOL108C Transcription factor involved in phospholipid synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
OPI1 YHL020C Transcriptional regulator of a variety of genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RAD53 YPL153C DNA damage response kinase regulation 1 1 1 protein kinase assay evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Negative Genetic
CEX1 YOR112W Component of nuclear aminoacylation-dependent tRNA export pathway genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Positive Genetic
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
ABD1 YBR236C Methyltransferase genetic 1 1 1 Positive Genetic
ADE13 YLR359W Adenylosuccinate lyase genetic 1 1 1 Negative Genetic
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 1 1 1 Positive Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
AEP1 YMR064W Protein required for expression of the mitochondrial OLI1 gene genetic 1 1 1 Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 1 1 1 Positive Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
BNA3 YJL060W Kynurenine aminotransferase genetic 1 1 1 Negative Genetic
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor genetic 1 1 1 Negative Genetic
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Positive Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
ADD66 YKL206C Protein involved in 20S proteasome assembly genetic 1 1 1 Positive Genetic
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CDC43 YGL155W Beta subunit of geranylgeranyltransferase type I genetic 1 1 1 Negative Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Synthetic Growth Defect
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
CBS2 YDR197W Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Negative Genetic
ALG7 YBR243C UDP-N-acetyl-glucosamine-1-P transferase genetic 1 1 1 Synthetic Rescue
ASP3-4 YLR160C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 PCA
QDR3 YBR043C Multidrug transporter of the major facilitator superfamily physical 1 1 1 PCA
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Biochemical Activity
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
DGA1 YOR245C Diacylglycerol acyltransferase genetic 1 1 1 Synthetic Lethality
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Synthetic Lethality
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Negative Genetic
VBA4 YDR119W Protein of unknown function genetic 1 1 1 Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIF2 YJL138C Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Positive Genetic
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
HXT4 YHR092C High-affinity glucose transporter genetic 1 1 1 Negative Genetic
GUK1 YDR454C Guanylate kinase genetic 1 1 1 Synthetic Rescue
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Synthetic Rescue
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
YIF1 YNL263C Integral membrane protein genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Synthetic Growth Defect
ROT2 YBR229C Glucosidase II catalytic subunit genetic 1 1 1 Synthetic Growth Defect
YBT1 YLL048C Transporter of the ATP-binding cassette (ABC) family genetic 1 1 1 Synthetic Growth Defect
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Negative Genetic
LEU9 YOR108W Alpha-isopropylmalate synthase II (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
COQ4 YDR204W Protein with a role in ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
PDE1 YGL248W Low-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Positive Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Positive Genetic
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase genetic 1 1 1 Negative Genetic
PUT2 YHR037W Delta-1-pyrroline-5-carboxylate dehydrogenase genetic 1 1 1 Positive Genetic
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase genetic 1 1 1 Negative Genetic
GDE1 YPL110C Glycerophosphocholine (GroPCho) phosphodiesterase genetic 1 1 1 Negative Genetic
FBP26 YJL155C Fructose-2,6-bisphosphatase, required for glucose metabolism genetic 1 1 1 Positive Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Positive Genetic
OAC1 YKL120W Mitochondrial inner membrane transporter genetic 1 1 1 Negative Genetic
MET16 YPR167C 3'-phosphoadenylsulfate reductase genetic 1 1 1 Negative Genetic
MET5 YJR137C Sulfite reductase beta subunit genetic 1 1 1 Positive Genetic
URA1 YKL216W Dihydroorotate dehydrogenase genetic 1 1 1 Positive Genetic
SPE3 YPR069C Spermidine synthase genetic 1 1 1 Positive Genetic
URA4 YLR420W Dihydroorotase genetic 1 1 1 Positive Genetic
SPE4 YLR146C Spermine synthase genetic 1 1 1 Negative Genetic
NCP1 YHR042W NADP-cytochrome P450 reductase genetic 1 1 1 Positive Genetic
SUC2 YIL162W Invertase genetic 1 1 1 Negative Genetic
PRS4 YBL068W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP genetic 1 1 1 Positive Genetic
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Positive Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
GCV3 YAL044C H subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Positive Genetic
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Negative Genetic
MPH3 YJR160C Alpha-glucoside permease genetic 1 1 1 Negative Genetic
COQ9 YLR201C Protein required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
TRP3 YKL211C Indole-3-glycerol-phosphate synthase genetic 1 1 1 Negative Genetic
ISN1 YOR155C Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase genetic 1 1 1 Positive Genetic
PHO87 YCR037C Low-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Positive Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Positive Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
JSN1 YJR091C Member of the Puf family of RNA-binding proteins genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Positive Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Positive Genetic
ELO3 YLR372W Elongase genetic 1 1 1 Positive Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Positive Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Positive Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Positive Genetic
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
CNE1 YAL058W Calnexin genetic 1 1 1 Positive Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
VPS60 YDR486C Protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Positive Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RCK1 YGL158W Protein kinase involved in oxidative stress response genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Positive Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Positive Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Positive Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 1 1 1 Positive Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Positive Genetic
HCA4 YJL033W DEAD box RNA helicase genetic 1 1 1 Positive Genetic
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Positive Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Positive Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Positive Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Positive Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Positive Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Positive Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 1 1 1 Positive Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Positive Genetic
YAL064W YAL064W Protein of unknown function genetic 1 1 1 Positive Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
TKL2 YBR117C Transketolase genetic 1 1 1 Positive Genetic
YBR196C-A YBR196C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 1 1 1 Positive Genetic
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase genetic 1 1 1 Positive Genetic
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Positive Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Positive Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Positive Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Positive Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
MSH1 YHR120W DNA-binding protein of the mitochondria genetic 1 1 1 Positive Genetic
DFG10 YIL049W Probable polyprenol reductase genetic 1 1 1 Positive Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Positive Genetic
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Positive Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
PDR8 YLR266C Transcription factor genetic 1 1 1 Positive Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall genetic 1 1 1 Positive Genetic
YMR030W-A YMR030W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
SDD2 YMR074C Protein with homology to human PDCD5 genetic 1 1 1 Positive Genetic
CIN4 YMR138W GTP-binding protein involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Positive Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Positive Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Positive Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Positive Genetic
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Positive Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
CIA1 YDR267C Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Negative Genetic
SUA5 YGL169W Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
MAS2 YHR024C Alpha subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Negative Genetic
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Negative Genetic
UBA1 YKL210W Ubiquitin activating enzyme (E1) genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 1 1 1 Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
TOP2 YNL088W Topoisomerase II genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
HEM4 YOR278W Uroporphyrinogen III synthase genetic 1 1 1 Negative Genetic
RRP12 YPL012W Protein required for export of the ribosomal subunits genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
RPL33A YPL143W Ribosomal 60S subunit protein L33A genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
FMN1 YDR236C Riboflavin kinase, produces riboflavin monophosphate (FMN) genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
HSF1 YGL073W Trimeric heat shock transcription factor genetic 1 1 1 Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) genetic 1 1 1 Negative Genetic
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
FLC2 YAL053W Putative calcium channel involved in calcium release under hypotonic genetic 1 1 1 Negative Genetic
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
YCL049C YCL049C Protein of unknown function genetic 1 1 1 Negative Genetic
PET18 YCR020C Protein of unknown function genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Negative Genetic
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
YDR042C YDR042C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
YDR061W YDR061W Protein with similarity to ABC transporter family members genetic 1 1 1 Negative Genetic
TVP15 YDR100W Integral membrane protein genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
SPR28 YDR218C Sporulation-specific homolog of the CDC3/10/11/12 family of genes genetic 1 1 1 Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
PFU1 YDR306C F-box protein that regulates pheromone-dependent morphogenesis genetic 1 1 1 Negative Genetic
HXT6 YDR343C High-affinity glucose transporter genetic 1 1 1 Negative Genetic
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex genetic 1 1 1 Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Negative Genetic
YHP1 YDR451C Homeobox transcriptional repressor genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
PFA5 YDR459C Palmitoyltransferase with autoacylation activity genetic 1 1 1 Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
QCR7 YDR529C Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Negative Genetic
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping genetic 1 1 1 Negative Genetic
NPP2 YEL016C Nucleotide pyrophosphatase/phosphodiesterase genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Negative Genetic
MAK10 YEL053C Non-catalytic subunit of the NatC N-terminal acetyltransferase genetic 1 1 1 Negative Genetic
HPA3 YEL066W D-Amino acid N-acetyltransferase that detoxifies D-amino acids genetic 1 1 1 Negative Genetic
HXT13 YEL069C Putative transmembrane polyol transporter genetic 1 1 1 Negative Genetic
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex genetic 1 1 1 Negative Genetic
FCY22 YER060W-A Putative purine-cytosine permease genetic 1 1 1 Negative Genetic
YER085C YER085C Putative protein of unknown function genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
RMD8 YFR048W Cytosolic protein required for sporulation genetic 1 1 1 Negative Genetic
YPS5 YGL259W Protein with similarity to GPI-anchored aspartic proteases genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
YER084W YER084W Protein of unknown function genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Negative Genetic
PHO90 YJL198W Low-affinity phosphate transporter genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
EMP70 YLR083C Protein with a role in cellular adhesion and filamentous growth genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
COQ2 YNR041C Para hydroxybenzoate polyprenyl transferase genetic 1 1 1 Negative Genetic
UBP2 YOR124C Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MTC6 YHR151C Protein of unknown function genetic 1 1 1 Negative Genetic
SSP1 YHR184W Protein involved in the control of meiotic nuclear division genetic 1 1 1 Negative Genetic
YHR213W YHR213W Pseudogenic fragment with similarity to flocculins genetic 1 1 1 Negative Genetic
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
KGD1 YIL125W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex genetic 1 1 1 Negative Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 1 1 1 Negative Genetic
YJL043W YJL043W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SIP4 YJL089W C6 zinc cluster transcriptional activator genetic 1 1 1 Negative Genetic
GZF3 YJL110C GATA zinc finger protein genetic 1 1 1 Negative Genetic
TMA22 YJR014W Protein of unknown function genetic 1 1 1 Negative Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
PGU1 YJR153W Endo-polygalacturonase genetic 1 1 1 Negative Genetic
YKL033W-A YKL033W-A Protein of unknown function genetic 1 1 1 Negative Genetic
YET1 YKL065C Endoplasmic reticulum transmembrane protein genetic 1 1 1 Negative Genetic
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
CWP2 YKL096W-A Covalently linked cell wall mannoprotein genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface genetic 1 1 1 Negative Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription genetic 1 1 1 Negative Genetic
YLL032C YLL032C Protein of unknown function genetic 1 1 1 Negative Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Negative Genetic
DCS1 YLR270W Non-essential hydrolase involved in mRNA decapping genetic 1 1 1 Negative Genetic
TMA10 YLR327C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Negative Genetic
CMP2 YML057W Calcineurin A genetic 1 1 1 Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
PET111 YMR257C Mitochondrial translational activator specific for the COX2 mRNA genetic 1 1 1 Negative Genetic
YMR272W-B YMR272W-B Protein of unknown function genetic 1 1 1 Negative Genetic
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein genetic 1 1 1 Negative Genetic
NGL2 YMR285C Protein involved in 5.8S rRNA processing genetic 1 1 1 Negative Genetic
YMR315W YMR315W Protein with NADP(H) oxidoreductase activity genetic 1 1 1 Negative Genetic
DIA1 YMR316W Protein of unknown function genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
SUN4 YNL066W Cell wall protein related to glucanases localized in birth scars genetic 1 1 1 Negative Genetic
YNL194C YNL194C Integral membrane protein genetic 1 1 1 Negative Genetic
SLZ1 YNL196C Sporulation-specific protein with a leucine zipper motif genetic 1 1 1 Negative Genetic
LAP3 YNL239W Cysteine aminopeptidase with homocysteine-thiolactonase activity genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
TOS6 YNL300W Glycosylphosphatidylinositol-dependent cell wall protein genetic 1 1 1 Negative Genetic
SKP2 YNL311C F-box protein of unknown function genetic 1 1 1 Negative Genetic
PUL4 YNR063W Putative zinc-cluster transcription factor genetic 1 1 1 Negative Genetic
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Negative Genetic
YAP7 YOL028C Transcriptional repressor of nitric oxide oxidase genetic 1 1 1 Negative Genetic
MAM3 YOL060C Protein involved in magnesium homeostasis genetic 1 1 1 Negative Genetic
REX4 YOL080C Putative RNA exonuclease genetic 1 1 1 Negative Genetic
TRM13 YOL125W 2'-O-methyltransferase genetic 1 1 1 Negative Genetic
IMA2 YOL157C Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) genetic 1 1 1 Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
TEA1 YOR337W Ty1 enhancer activator involved in Ty enhancer-mediated transcription genetic 1 1 1 Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Negative Genetic
MFM1 YPL060W Mitochondrial inner membrane magnesium transporter genetic 1 1 1 Negative Genetic
RPL1A YPL220W Ribosomal 60S subunit protein L1A genetic 1 1 1 Negative Genetic
CMR3 YPR013C Putative zinc finger protein genetic 1 1 1 Negative Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
ERV2 YPR037C Flavin-linked sulfhydryl oxidase localized to the ER lumen genetic 1 1 1 Negative Genetic
MAK3 YPR051W Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) genetic 1 1 1 Negative Genetic
YPR114W YPR114W Protein distantly similar to ceramide synthases, Lag1p and Lac1p genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Phenotypic Suppression
SAM2 YDR502C S-adenosylmethionine synthetase genetic 1 1 1 Phenotypic Suppression
SAH1 YER043C S-adenosyl-L-homocysteine hydrolase genetic 1 1 1 Synthetic Rescue
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Phenotypic Enhancement
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes genetic 1 1 1 Phenotypic Enhancement
EPS1 YIL005W ER protein with chaperone and co-chaperone activity genetic 1 1 1 Negative Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
ECM38 YLR299W Gamma-glutamyltranspeptidase genetic 1 1 1 Negative Genetic
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 1 1 1 Negative Genetic
ULA1 YPL003W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Negative Genetic
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Positive Genetic
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 1 1 1 Positive Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
SAM35 YHR083W Component of the sorting and assembly machinery (SAM) complex genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
PBA1 YLR199C Protein involved in 20S proteasome assembly genetic 1 1 1 Positive Genetic
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 1 1 1 Negative Genetic
REC102 YLR329W Protein involved in early stages of meiotic recombination genetic 1 1 1 Negative Genetic
STB4 YMR019W Putative transcription factor genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
RNH1 YMR234W Ribonuclease H1 genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Positive Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Positive Genetic
ROX1 YPR065W Heme-dependent repressor of hypoxic genes genetic 1 1 1 Negative Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 1 1 1 Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Positive Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 1 1 1 Positive Genetic
UCC1 YLR224W F-box protein and component of SCF ubiquitin ligase complexes genetic 1 1 1 Negative Genetic
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Positive Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Positive Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Positive Genetic
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p genetic 1 1 1 Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Phenotypic Suppression
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Phenotypic Suppression
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
ASP3-2 YLR157C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic
BSC4 YNL269W Protein of unknown function genetic 1 1 1 Negative Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Positive Genetic
ALG11 YNL048W Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Positive Genetic