| LAS17 |
YOR181W |
Actin assembly factor |
physical |
16 |
6 |
13 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Co-localization, PCA, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS |
| MYO5 |
YMR109W |
One of two type I myosin motors |
physical |
15 |
5 |
11 |
Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Co-localization, PCA, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Two-hybrid |
| MYO3 |
YKL129C |
One of two type I myosins |
physical |
10 |
3 |
6 |
Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
7 |
2 |
5 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
6 |
2 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
5 |
3 |
5 |
Dosage Rescue, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Positive Genetic |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
genetic |
5 |
2 |
4 |
Synthetic Rescue, Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
5 |
3 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid, Far Western, Reconstituted Complex |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
4 |
2 |
4 |
Dosage Rescue, Dosage Rescue, Negative Genetic, Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
4 |
2 |
4 |
Two-hybrid, PCA, Two-hybrid, PCA |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
physical |
4 |
2 |
3 |
Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Synthetic Lethality |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
3 |
2 |
3 |
Positive Genetic, Dosage Rescue, Positive Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
3 |
3 |
2 |
Synthetic Lethality, Phenotypic Suppression, Negative Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Positive Genetic, Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PRK1 |
YIL095W |
Ser/Thr protein kinase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UBP1 |
YDL122W |
Ubiquitin-specific protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MTC6 |
YHR151C |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CLC1 |
YGR167W |
Clathrin light chain |
genetic |
3 |
3 |
1 |
Positive Genetic, Synthetic Rescue, Phenotypic Suppression |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Rescue |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BNI1 |
YNL271C |
Formin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPR097W |
YPR097W |
Protein that contains a PX domain and binds phosphoinositides |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BEM3 |
YPL115C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
physical |
2 |
1 |
2 |
PCA, PCA |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TCM62 |
YBR044C |
Protein involved in assembly of the succinate dehydrogenase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| AVT3 |
YKL146W |
Vacuolar transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KIN82 |
YCR091W |
Putative serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PKH3 |
YDR466W |
Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PMP2 |
YEL017C-A |
Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTK1 |
YKL198C |
Putative serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SOL4 |
YGR248W |
6-phosphogluconolactonase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MTC4 |
YBR255W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| YIL102C |
YIL102C |
Putative protein of unknown function |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Phenotypic Suppression |
| TKL1 |
YPR074C |
Transketolase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| KIN1 |
YDR122W |
S/T protein kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ADD66 |
YKL206C |
Protein involved in 20S proteasome assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| MYO5 |
YMR109W |
One of two type I myosin motors |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MTC2 |
YKL098W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MAY24 |
YPR153W |
Peripheral ER membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CEF1 |
YMR213W |
Essential splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LTO1 |
YNL260C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMW1 |
YNL313C |
Essential conserved protein with a role in cell wall integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUS1 |
YPL212C |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM3 |
YDL112W |
2'-O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC19 |
YKL013C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX4 |
YGL187C |
Subunit IV of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FET5 |
YFL041W |
Multicopper oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HTB2 |
YBL002W |
Histone H2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
PCA |
| LSM4 |
YER112W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| INP2 |
YMR163C |
Peroxisome-specific receptor important for peroxisome inheritance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLH1 |
YMR167W |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MRPL39 |
YML009C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO1 |
YHR023W |
Type II myosin heavy chain |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BLM10 |
YFL007W |
Proteasome activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD16 |
YBR114W |
Nucleotide excision repair (NER) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RKM1 |
YPL208W |
SET-domain lysine-N-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRI1 |
YDL216C |
Catalytic subunit of the COP9 signalosome (CSN) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
PCA |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
physical |
1 |
1 |
1 |
PCA |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Protein-RNA |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YMC2 |
YBR104W |
Putative mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YUR1 |
YJL139C |
Mannosyltransferase involved in protein N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMD8 |
YML038C |
Putative nucleotide sugar transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YET2 |
YMR040W |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YSY6 |
YBR162W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPL225W |
YPL225W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YOL164W-A |
YOL164W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YBR138C |
YBR138C |
Cytoplasmic protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR090C |
YCR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCR102C |
YCR102C |
Putative quinone oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFH7 |
YFR007W |
Putative kinase with similarity to the PRK/URK/PANK kinase subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBP2 |
YGL060W |
Central kinetochore associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR152C |
YLR152C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBL055C |
YBL055C |
3'-->5' exonuclease and endonuclease with a possible role in apoptosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR197C |
YBR197C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL242C |
YGL242C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHL008C |
YHL008C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR078W |
YHR078W |
High osmolarity-regulated gene of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL206C |
YJL206C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL075C |
YKL075C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME2 |
YMR302C |
Integral inner mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL134C |
YNL134C |
NADH-dependent aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR029C |
YNR029C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YSP3 |
YOR003W |
Putative precursor of the subtilisin-like protease III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR365C |
YOR365C |
Putative protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML002W |
YML002W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR381W-A |
YOR381W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR114W |
YPR114W |
Protein distantly similar to ceramide synthases, Lag1p and Lac1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YOR268C |
YOR268C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIP5 |
YGL161C |
Protein that interacts with Rab GTPases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD10 |
YML095C |
Single-stranded DNA endonuclease (with Rad1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA20 |
YER007C-A |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDH1 |
YKL085W |
Mitochondrial malate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG31 |
YDR022C |
Autophagy-specific protein required for autophagosome formation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMP2 |
YML057W |
Calcineurin A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSH49 |
YOR319W |
U2-snRNP associated splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC12 |
YLR306W |
Enzyme that mediates the conjugation of Rub1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG42 |
YBR139W |
Vacuolar serine-type carboxypeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIP1 |
YMR092C |
Actin cortical patch component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ADH4 |
YGL256W |
Alcohol dehydrogenase isoenzyme type IV |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LRO1 |
YNR008W |
Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KIN2 |
YLR096W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
PCA |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EPT1 |
YHR123W |
sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP53 |
YPL146C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDE1 |
YMR145C |
Mitochondrial external NADH dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CBR1 |
YIL043C |
Cytochrome b reductase and NADH-dependent reductase for Dph3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADH6 |
YMR318C |
NADPH-dependent medium chain alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARO9 |
YHR137W |
Aromatic aminotransferase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ATG13 |
YPR185W |
Regulatory subunit of the Atg1p signaling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACA1 |
YER045C |
ATF/CREB family basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT4 |
YOR348C |
Proline permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCO14 |
YHL018W |
Putative 4a-hydroxytetrahydrobiopterin dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAP4 |
YGL229C |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMD1 |
YDL001W |
Cytoplasmic protein required for sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISY1 |
YJR050W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB17 |
YDL146W |
Protein involved in the regulation of endocytosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX13 |
YLR191W |
Peroxisomal importomer complex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRF1 |
YGR246C |
TFIIIB B-related factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SFH1 |
YLR321C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AMD1 |
YML035C |
AMP deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOP1 |
YIL072W |
Meiosis-specific protein required for chromosome synapsis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MYO3 |
YKL129C |
One of two type I myosins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRK1 |
YIL095W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSM19 |
YNR037C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL10 |
YBR019C |
UDP-glucose-4-epimerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAP1 |
YKR039W |
General amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIC1 |
YHR061C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSO1 |
YNR049C |
Lipid-interacting protein in SNARE complex assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARK1 |
YNL020C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIP3 |
YNL257C |
Putative sterol transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AZF1 |
YOR113W |
Zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPR6 |
YER115C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HMS1 |
YOR032C |
bHLH protein with similarity to myc-family transcription factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PXA1 |
YPL147W |
Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VPS28 |
YPL065W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ENT1 |
YDL161W |
Epsin-like protein involved in endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBP1 |
YJL209W |
Mitochondrial protein, regulator of COB mRNA stability and translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYP1 |
YCR030C |
Negative regulator of WASP-Arp23 complex |
physical |
1 |
1 |
1 |
PCA |
| SYP1 |
YCR030C |
Negative regulator of WASP-Arp23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB5 |
YDR079C-A |
Component of RNA polymerase II general transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASG1 |
YIL130W |
Zinc cluster protein proposed to be a transcriptional regulator |
physical |
1 |
1 |
1 |
Two-hybrid |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAR32 |
YDL173W |
Low complexity protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGU1 |
YJR153W |
Endo-polygalacturonase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP31 |
YDR533C |
Methylglyoxalase that converts methylglyoxal to D-lactate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUL4 |
YJR036C |
Protein with similarity to hect domain E3 ubiquitin-protein ligases |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| BSC6 |
YOL137W |
Protein of unknown function with 8 putative transmembrane segments |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUF4 |
YGL014W |
Member of the PUF protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICL1 |
YER065C |
Isocitrate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC22 |
YEL001C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNN1 |
YNL086W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA2 |
YER071C |
Subunit of a complex that associates with actin filaments |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLG1 |
YKR058W |
Glycogenin glucosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIG2 |
YCR089W |
Cell wall adhesin, expressed specifically during mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRT5 |
YFR032C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LOT6 |
YLR011W |
FMN-dependent NAD(P)H:quinone reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USA1 |
YML029W |
Scaffold subunit of the Hrd1p ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NQM1 |
YGR043C |
Transaldolase of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADE12 |
YNL220W |
Adenylosuccinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PGS1 |
YCL004W |
Phosphatidylglycerolphosphate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| JID1 |
YPR061C |
Probable Hsp40p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS24 |
YBR214W |
Protein involved in cell separation during budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDD2 |
YMR074C |
Protein with homology to human PDCD5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS6 |
YJL099W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| UFD4 |
YKL010C |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM11 |
YER093C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHO90 |
YJL198W |
Low-affinity phosphate transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| AGE1 |
YDR524C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DAP2 |
YHR028C |
Dipeptidyl aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RKM4 |
YDR257C |
Ribosomal lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET5 |
YHR207C |
Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCL1 |
YPL056C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PCK1 |
YKR097W |
Phosphoenolpyruvate carboxykinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA3 |
YHR009C |
Putative oxidoreductase involved in late endosome to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NRM1 |
YNR009W |
Transcriptional co-repressor of MBF-regulated gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPO14 |
YKR031C |
Phospholipase D |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX31 |
YGR004W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| EAR1 |
YMR171C |
Specificity factor required for Rsp5p-dependent ubiquitination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARF3 |
YOR094W |
Glucose-repressible ADP-ribosylation factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COM2 |
YER130C |
Transcription factor that binds IME1 Upstream Activation Signal (UAS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSY1 |
YDR160W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ITR1 |
YDR497C |
Myo-inositol transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERP4 |
YOR016C |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERS1 |
YCR075C |
Protein involved in cystine transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCD1 |
YHR003C |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK31 |
YCR020C-A |
Non-catalytic subunit of N-terminal acetyltransferase of the NatC type |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPT1 |
YDR399W |
Dimeric hypoxanthine-guanine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPE1 |
YJL121C |
D-ribulose-5-phosphate 3-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFA4 |
YOL003C |
Palmitoyltransferase with autoacylation activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIT3 |
YOR383C |
Mannoprotein that is incorporated into the cell wall |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELO1 |
YJL196C |
Elongase I, medium-chain acyl elongase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AVT5 |
YBL089W |
Putative transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX8 |
YGR077C |
Intraperoxisomal organizer of the peroxisomal import machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSB1 |
YOR049C |
Sphingoid long-chain base (LCB) efflux transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APA2 |
YDR530C |
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBL1 |
YHR199C-A |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAT4 |
YMR069W |
N alpha-acetyl-transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MPC1 |
YGL080W |
Highly conserved subunit of mitochondrial pyruvate carrier (MPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CMC2 |
YBL059C-A |
Protein involved in respiratory chain complex assembly or maintenance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LMO1 |
YLL007C |
Homolog of mammalian ELMO (Engulfment and celL MOtility) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM20 |
YIL158W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COX16 |
YJL003W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DLT1 |
YMR126C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM19 |
YIL087C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HEM25 |
YDL119C |
Mitochondrial glycine transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALD3 |
YMR169C |
Cytoplasmic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTR86 |
YCR054C |
Essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROT2 |
YBR229C |
Glucosidase II catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI1 |
YGR216C |
Membrane protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIN10 |
YDR387C |
Putative transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRM7 |
YDL039C |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NCA2 |
YPR155C |
Protein that regulates expression of Fo-F1 ATP synthase subunits |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBT1 |
YKL208W |
Protein involved in 5' RNA end processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OPI10 |
YOL032W |
Protein with a possible role in phospholipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET100 |
YDR079W |
Chaperone that facilitates the assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UTP30 |
YKR060W |
Subunit of U3-containing 90S preribosome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIF1 |
YNR074C |
Mitochondrial cell death effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LRE1 |
YCL051W |
Protein involved in control of cell wall structure and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCE101 |
YJL205C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MME1 |
YMR166C |
Transporter of the mitochondrial inner membrane that exports magnesium |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOL3 |
YHR163W |
6-phosphogluconolactonase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMD9 |
YGL107C |
Mitochondrial protein that controls mitochondrial gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC10 |
YBR265W |
3-ketosphinganine reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRX15 |
YNR040W |
Membrane-associated mitoribosome receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRF1 |
YDL133W |
Regulator of phospholipase D (Spo14p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPS2 |
YDR522C |
Protein expressed during sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOP4 |
YJL192C |
ER-membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM10 |
YOL093W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA6 |
YDR067C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDD1 |
YEL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SVS1 |
YPL163C |
Cell wall and vacuolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TOS1 |
YBR162C |
Covalently-bound cell wall protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TYW3 |
YGL050W |
tRNA methyltransferase required for synthesis of wybutosine |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
