| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
11 |
3 |
10 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
9 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
8 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex |
| CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
8 |
1 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
8 |
1 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
7 |
3 |
6 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Positive Genetic, Phenotypic Enhancement, Positive Genetic, Positive Genetic |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
physical |
7 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
6 |
3 |
6 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic |
| HHF1 |
YBR009C |
Histone H4 |
physical |
6 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
6 |
2 |
5 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
5 |
1 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
5 |
1 |
5 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| HHT1 |
YBR010W |
Histone H3 |
physical |
5 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Protein-peptide |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
physical |
5 |
3 |
3 |
Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-RNA |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
4 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
4 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
4 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic |
| IOC4 |
YMR044W |
Member of a complex (Isw1b) with Isw1p and Ioc2p |
genetic |
4 |
2 |
3 |
Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
4 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| AIR1 |
YIL079C |
Zinc knuckle protein |
genetic |
3 |
3 |
3 |
Phenotypic Enhancement, Negative Genetic, Synthetic Lethality |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
3 |
2 |
3 |
Phenotypic Suppression, Positive Genetic, Positive Genetic |
| RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
| SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Lethality |
| ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Phenotypic Enhancement |
| NOP16 |
YER002W |
Constituent of 66S pre-ribosomal particles |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Rescue |
| AIR2 |
YDL175C |
RNA-binding subunit of the TRAMP nuclear RNA surveillance complex |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
| HHF2 |
YNL030W |
Histone H4 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IOC2 |
YLR095C |
Subunit of the Isw1b complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STP3 |
YLR375W |
Zinc-finger protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MCM2 |
YBL023C |
Protein involved in DNA replication |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| JEM1 |
YJL073W |
DnaJ-like chaperone required for nuclear membrane fusion during mating |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YJR120W |
YJR120W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RRT2 |
YBR246W |
Methylesterase performing penultimate step of diphthamide biosynthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| INO2 |
YDR123C |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MET16 |
YPR167C |
3'-phosphoadenylsulfate reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
2 |
1 |
1 |
PCA, PCA |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PSF2 |
YJL072C |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHF2 |
YNL030W |
Histone H4 |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSH49 |
YOR319W |
U2-snRNP associated splicing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NPL3 |
YDR432W |
RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
physical |
1 |
1 |
1 |
Two-hybrid |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHT1 |
YBR010W |
Histone H3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHT2 |
YNL031C |
Histone H3 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDP3 |
YLR455W |
Component of the NuA3b histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDI1 |
YDL135C |
Rho GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN14 |
YGL004C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RMD5 |
YDR255C |
Component of GID Complex that confers ubiquitin ligase (U3) activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MEF1 |
YLR069C |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP13 |
YNL175C |
Nucleolar protein found in preribosomal complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSA1 |
YPR174C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIR2 |
YDR152W |
Highly-acidic RWD domain-containing cytoplasmic protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM9 |
YML014W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP1 |
YPL119C |
ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LIN1 |
YHR156C |
Non-essential component of U5 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GFD1 |
YMR255W |
Coiled-coiled protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MPP6 |
YNR024W |
Nuclear exosome-associated RNA binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIF3 |
YPR163C |
Translation initiation factor eIF-4B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFH1 |
YDL120W |
Mitochondrial matrix iron chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NSI1 |
YDR026C |
RNA polymerase I termination factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET28 |
YIR017C |
bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IOC3 |
YFR013W |
Subunit of the Isw1a complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP43 |
YCR035C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM6 |
YGL201C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF11 |
YMR260C |
Translation initiation factor eIF1A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOG1 |
YPL093W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLD3 |
YGL113W |
Protein involved in the initiation of DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP23 |
YBR047W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPB4 |
YDR121W |
Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STL1 |
YDR536W |
Glycerol proton symporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL068C |
YJL068C |
Esterase that can function as an S-formylglutathione hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRY3 |
YJL078C |
GPI-anchored cell wall protein involved in export of sterols |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRT3 |
YKL175W |
Vacuolar membrane zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR068C |
YNR068C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSB1 |
YOR049C |
Sphingoid long-chain base (LCB) efflux transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPS16 |
YPL013C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SND1 |
YDR186C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYM1 |
YDR430C |
Lysine-specific metalloprotease of the pitrilysin family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP3 |
YDR473C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX4 |
YGR133W |
Peroxisomal ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC17 |
YJL011C |
RNA polymerase III subunit C17 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF6 |
YJR082C |
Subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIR2 |
YOR010C |
Putative cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO4 |
YOR040W |
Mitochondrial glyoxalase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUS1 |
YPL212C |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR363W-A |
YLR363W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAE2 |
YGL175C |
Endonuclease required for telomere elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIP20 |
YGL145W |
Peripheral membrane protein required for COPI vesicle fusion to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DDC1 |
YPL194W |
DNA damage checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YEN1 |
YER041W |
Holliday junction resolvase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRX1 |
YOL077C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADA2 |
YDR448W |
Transcription coactivator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABF2 |
YMR072W |
Mitochondrial DNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BOI1 |
YBL085W |
Protein involved in polar growth, functionally redundant with Boi2p |
physical |
1 |
1 |
1 |
Two-hybrid |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AAT2 |
YLR027C |
Cytosolic aspartate aminotransferase involved in nitrogen metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BRN1 |
YBL097W |
Subunit of the condensin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAF16 |
YFL028C |
Part of evolutionarily-conserved CCR4-NOT regulatory complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AUA1 |
YFL010W-A |
Protein required for the negative regulation by ammonia of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ADE12 |
YNL220W |
Adenylosuccinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AZR1 |
YGR224W |
Plasma membrane transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APA2 |
YDR530C |
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
