| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
11 |
4 |
9 |
Affinity Capture-MS, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Reconstituted Complex |
| CYR1 |
YJL005W |
Adenylate cyclase |
physical |
10 |
4 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
physical |
8 |
5 |
8 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Protein-peptide, Protein-peptide, Two-hybrid, Co-fractionation |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
physical |
7 |
4 |
6 |
Two-hybrid, Two-hybrid, Affinity Capture-Western, PCA, Reconstituted Complex, PCA, Reconstituted Complex |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
7 |
5 |
5 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Rescue, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Positive Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
4 |
4 |
4 |
Dosage Rescue, Synthetic Rescue, Synthetic Lethality, Negative Genetic |
| AIP1 |
YMR092C |
Actin cortical patch component |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Lethality |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
4 |
3 |
2 |
Synthetic Haploinsufficiency, Positive Genetic, Negative Genetic, Negative Genetic |
| TWF1 |
YGR080W |
Twinfilin |
physical |
3 |
3 |
3 |
PCA, Affinity Capture-MS, Reconstituted Complex |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
3 |
3 |
3 |
Phenotypic Enhancement, Negative Genetic, Synthetic Lethality |
| TWF1 |
YGR080W |
Twinfilin |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Synthetic Lethality |
| CDC43 |
YGL155W |
Beta subunit of geranylgeranyltransferase type I |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
3 |
2 |
2 |
Negative Genetic, Positive Genetic, Negative Genetic |
| BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
3 |
2 |
2 |
Negative Genetic, Positive Genetic, Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
| TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| KEX1 |
YGL203C |
Cell death protease essential for hypochlorite-induced apoptosis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ROT2 |
YBR229C |
Glucosidase II catalytic subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Positive Genetic |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-Western |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Dosage Lethality |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BIL1 |
YOR304C-A |
Protein that binds Bud6p and has a role in actin cable assembly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OCA6 |
YDR067C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| NBL1 |
YHR199C-A |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CAP1 |
YKL007W |
Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| AIM21 |
YIR003W |
Subunit of a complex that associates with actin filaments |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CYR1 |
YJL005W |
Adenylate cyclase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MLC2 |
YPR188C |
Regulatory light chain for the type II myosin Myo1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPA2 |
YLL021W |
Component of the polarisome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DFG5 |
YMR238W |
Putative mannosidase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| APS1 |
YLR170C |
Small subunit of the clathrin-associated adaptor complex AP-1 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CHS6 |
YJL099W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SRL1 |
YOR247W |
Mannoprotein that exhibits a tight association with the cell wall |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MTC6 |
YHR151C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RAD53 |
YPL153C |
DNA damage response kinase |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS22 |
YKL193C |
Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCA4 |
YJL033W |
DEAD box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC37 |
YKR025W |
RNA polymerase III subunit C37 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARC19 |
YKL013C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
PCA |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTO1 |
YCR015C |
Protein required for cold tolerance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ATP22 |
YDR350C |
Specific translational activator for the mitochondrial ATP6 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML3 |
YBR107C |
Outer kinetochore protein and component of the Ctf19 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST1 |
YNL265C |
Protein with positive role in the multivesicular body sorting pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KGD1 |
YIL125W |
Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM2 |
YBL026W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM6 |
YGL201C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST1 |
YJL002C |
Alpha subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA14 |
YMR061W |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC13 |
YLR208W |
Structural component of 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
PCA |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLC1 |
YDL052C |
1-acyl-sn-glycerol-3-phosphate acyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP38 |
YGR075C |
Unique component of the U4/U6.U5 tri-snRNP particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CRN1 |
YLR429W |
Coronin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP4 |
YPL078C |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
physical |
1 |
1 |
1 |
PCA |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSH49 |
YOR319W |
U2-snRNP associated splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC53 |
YFL045C |
Phosphomannomutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO81 |
YGR233C |
Cyclin-dependent kinase (CDK) inhibitor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DYN2 |
YDR424C |
Cytoplasmic light chain dynein, microtubule motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIP1 |
YMR092C |
Actin cortical patch component |
physical |
1 |
1 |
1 |
Two-hybrid |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO12 |
YHR152W |
Nucleolar protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET6 |
YER091C |
Cobalamin-independent methionine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC7 |
YHR076W |
Type 2C serine/threonine protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIS4 |
YML006C |
CAAX box containing protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIP5 |
YFR016C |
Protein that positively regulates actin assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGI1 |
YER067W |
Protein involved in energy metabolism under respiratory conditions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDP1 |
YIL113W |
Stress-inducible dual-specificity MAP kinase phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAA1 |
YJL207C |
AP-1 accessory protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD53 |
YPL153C |
DNA damage response kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFU1 |
YDR306C |
F-box protein that regulates pheromone-dependent morphogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRS2 |
YER099C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CMG1 |
YLR271W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX15 |
YOL044W |
Tail-anchored type II integral peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QCR7 |
YDR529C |
Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH203 |
YLR154C |
Ribonuclease H2 subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APL4 |
YPR029C |
Gamma-adaptin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP13 |
YLR222C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRM5 |
YHR070W |
tRNA(m(1)G37)methyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Co-fractionation |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Co-fractionation |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YVC1 |
YOR087W |
Vacuolar cation channel |
physical |
1 |
1 |
1 |
PCA |
| URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIP20 |
YGL145W |
Peripheral membrane protein required for COPI vesicle fusion to the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YDR042C |
YDR042C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIM21 |
YGR033C |
Nonessential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR154C-H |
YLR154C-H |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRM9 |
YML014W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC1 |
YDR177W |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPI1 |
YFR003C |
Regulatory subunit of the type I protein phosphatase (PP1) Glc7p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URB2 |
YJR041C |
Protein required for normal metabolism of the rRNA primary transcript |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI80 |
YOR143C |
Thiamine pyrophosphokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB2 |
YPL122C |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB4 |
YPR056W |
Subunit of TFIIH complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR016W |
YBR016W |
Tail-anchored plasma membrane protein with a conserved CYSTM module |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UGA2 |
YBR006W |
Succinate semialdehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOS1 |
YBR162C |
Covalently-bound cell wall protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA2 |
YER071C |
Subunit of a complex that associates with actin filaments |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL036W |
YGL036W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUT1 |
YGL162W |
Zn(II)2Cys6 family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL176C |
YGL176C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL054W |
YIL054W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL092W |
YIL092W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUM1 |
YOR251C |
Rhodanese domain sulfur transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THP3 |
YPR045C |
Protein that may have a role in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TKL2 |
YBR117C |
Transketolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCL068C |
YCL068C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YSP2 |
YDR326C |
Sterol-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR476C |
YDR476C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP5 |
YER144C |
Putative ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR016W |
YGR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR078W |
YHR078W |
High osmolarity-regulated gene of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR086W-A |
YHR086W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL193W |
YJL193W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR115W |
YJR115W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YEH1 |
YLL012W |
Steryl ester hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR084W |
YMR084W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR099C |
YMR099C |
Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THI12 |
YNL332W |
Protein involved in synthesis of the thiamine precursor HMP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMC1 |
YOR052C |
AN1-type zinc finger protein, effector of proteotoxic stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR089W |
YPR089W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPO3 |
YPR156C |
Polyamine transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWT1 |
YOR166C |
RNA endoribonuclease involved in perinuclear mRNP quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL046W-A |
YIL046W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR363W-A |
YLR363W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPL245W |
YPL245W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| XBP1 |
YIL101C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR315W |
YMR315W |
Protein with NADP(H) oxidoreductase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UFD4 |
YKL010C |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EBS1 |
YDR206W |
Protein involved in translation inhibition and nonsense-mediated decay |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP5 |
YBR237W |
RNA helicase in the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBA1 |
YOL070C |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTC20 |
YBR188C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX14 |
YGL153W |
Central component of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC6 |
YFR043C |
Clathrin coat accessory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SER33 |
YIL074C |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUB1 |
YPL260W |
Conserved fungal gene linked to DNA repair and proteasome function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX13 |
YLR191W |
Peroxisomal importomer complex component |
physical |
1 |
1 |
1 |
Two-hybrid |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRF1 |
YGR246C |
TFIIIB B-related factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MYO5 |
YMR109W |
One of two type I myosin motors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC6 |
YIL068C |
Essential 88kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFI1 |
YLL003W |
Centrin (Cdc31p)-binding protein required for SPB duplication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMP46 |
YLR080W |
Integral membrane component of ER-derived COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUS2 |
YMR232W |
Cell fusion regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PPR1 |
YLR014C |
Zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCO1 |
YBR037C |
Copper-binding protein of mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNR1 |
YIL159W |
Formin |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RAD2 |
YGR258C |
Single-stranded DNA endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRI2 |
YOL117W |
Subunit of the COP9 signalosome (CSN) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HFA1 |
YMR207C |
Mitochondrial acetyl-coenzyme A carboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ1 |
YBR003W |
Hexaprenyl pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX25 |
YPL112C |
Peripheral peroxisomal membrane peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC114 |
YMR133W |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX27 |
YOR193W |
Peripheral peroxisomal membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUS1 |
YCL027W |
Membrane protein localized to the shmoo tip |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCH1 |
YGR217W |
Voltage-gated high-affinity calcium channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
physical |
1 |
1 |
1 |
PCA |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EIS1 |
YMR031C |
Component of the eisosome required for proper eisosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNU13 |
YEL026W |
RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIT1 |
YEL007W |
Transcriptional regulator of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOT13 |
YKL084W |
Zinc-binding mitochondrial intermembrane space (IMS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBN1 |
YCL052C |
Component of glycosylphosphatidylinositol-mannosyltransferase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPS1 |
YJL172W |
Vacuolar carboxypeptidase S |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP31 |
YDR533C |
Methylglyoxalase that converts methylglyoxal to D-lactate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNS1 |
YGR230W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX15 |
YER141W |
Heme a synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIG3 |
YER028C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCE102 |
YPR149W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET17 |
YLR303W |
O-acetyl homoserine-O-acetyl serine sulfhydrylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRN1 |
YGR093W |
Splicing factor that modulates turnover of branched RNAs by Dbr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOK1 |
YDR006C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AEP3 |
YPL005W |
Peripheral mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTG1 |
YMR097C |
Putative GTPase peripheral to the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IAI11 |
YBL059W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR10 |
YOR328W |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANY1 |
YMR010W |
Protein involved in phospholipid flippase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIN7 |
YDR263C |
Mitochondrial nuclease functioning in DNA repair and replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIP4 |
YAL031C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APD1 |
YBR151W |
2Fe-2S cytosolic protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSA1 |
YPR174C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGE1 |
YDR524C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNY1 |
YPL123C |
Vacuolar RNase of the T(2) family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM7 |
YLR443W |
Putative integral membrane protein with a role in calcium uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RKI1 |
YOR095C |
Ribose-5-phosphate ketol-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GIS1 |
YDR096W |
Histone demethylase and transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOR1 |
YDR366C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECL1 |
YGR146C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APE4 |
YHR113W |
Cytoplasmic aspartyl aminopeptidase with possible vacuole function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO11 |
YHL022C |
Meiosis-specific protein required for meiotic recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COM2 |
YER130C |
Transcription factor that binds IME1 Upstream Activation Signal (UAS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO1 |
YJL153C |
Inositol-3-phosphate synthase |
physical |
1 |
1 |
1 |
PCA |
| LSO2 |
YGR169C-A |
Ribosome-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KRE9 |
YJL174W |
Glycoprotein involved in cell wall beta-glucan assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC2 |
YML055W |
Subunit of signal peptidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLM4 |
YBR077C |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC2 |
YKL098W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD16 |
YEL029C |
Putative pyridoxal kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFA4 |
YOL003C |
Palmitoyltransferase with autoacylation activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAT1 |
YML113W |
DNA binding protein that recognizes oligo(dA).oligo(dT) tracts |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE4 |
YDL231C |
Zinc finger protein containing five transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX4 |
YGR133W |
Peroxisomal ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIR3 |
YKL163W |
O-glycosylated covalently-bound cell wall protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPL1 |
YDR294C |
Dihydrosphingosine phosphate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTS1 |
YPR033C |
Cytoplasmic and mitochondrial histidine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLD1 |
YPR109W |
Component of Dsc E3 ligase complex in Golgi and endosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMP2 |
YMR035W |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HBN1 |
YCL026C-B |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMA2 |
YOL157C |
Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC3 |
YKL207W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DLT1 |
YMR126C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BER1 |
YLR412W |
Protein involved in microtubule-related processes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUP2 |
YPL189W |
Probable membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMF2 |
YHR050W |
Divalent metal ion transporter involved in manganese homeostasis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX35 |
YGR168C |
Regulator of peroxisome abundance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTS2 |
YDR371W |
Putative chitinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBT1 |
YKL208W |
Protein involved in 5' RNA end processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILT1 |
YDR090C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REE1 |
YJL217W |
Cytoplasmic protein involved in the regulation of enolase (ENO1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET100 |
YDR079W |
Chaperone that facilitates the assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEI1 |
YLR404W |
Seipin involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RQC1 |
YDR333C |
Component of the ribosome quality control complex (RQC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM38 |
YLR299W |
Gamma-glutamyltranspeptidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIM1 |
YIL123W |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
1 |
1 |
1 |
Positive Genetic |
| REX3 |
YLR107W |
RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCF3 |
YBR255C-A |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLH1 |
YGR271W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLO1 |
YER180C-A |
Protein interacting with Arl3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAY24 |
YPR153W |
Peripheral ER membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE10 |
YGL228W |
Protein involved in outer spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIN4 |
YML007C-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
