| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
9 |
4 |
6 |
Dosage Lethality, Phenotypic Enhancement, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PTK1 |
YKL198C |
Putative serine/threonine protein kinase |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CYC2 |
YOR037W |
Mitochondrial peripheral inner membrane protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
3 |
2 |
3 |
Negative Genetic, Dosage Growth Defect, Negative Genetic |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HER1 |
YOR227W |
Protein of unknown function |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MRX8 |
YDR336W |
Protein that associates with mitochondrial ribosome |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
2 |
2 |
2 |
PCA, Biochemical Activity |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-RNA |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
| SIP5 |
YMR140W |
Protein of unknown function |
physical |
2 |
2 |
2 |
Biochemical Activity, Reconstituted Complex |
| SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
2 |
2 |
2 |
Positive Genetic, Dosage Rescue |
| URA6 |
YKL024C |
Uridylate kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATP11 |
YNL315C |
Molecular chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MRPL44 |
YMR225C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| EST3 |
YIL009C-A |
Component of the telomerase holoenzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSM2 |
YIL132C |
Subunit of the Shu complex (aka PCSS complex) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| GDS1 |
YOR355W |
Protein involved in histone H4 acetylation at ribosomal protein genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| APC9 |
YLR102C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CQD1 |
YPL109C |
UbiB family mitochondrial protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DUS3 |
YLR401C |
Dihydrouridine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRH1 |
YDR033W |
Protein that localizes primarily to the plasma membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FMS1 |
YMR020W |
Polyamine oxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RMD1 |
YDL001W |
Cytoplasmic protein required for sporulation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIP1 |
YEL024W |
Ubiquinol-cytochrome-c reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPT31 |
YER031C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STP1 |
YDR463W |
Transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VHR1 |
YIL056W |
Transcriptional activator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YHP1 |
YDR451C |
Homeobox transcriptional repressor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTK1 |
YDL025C |
Putative protein kinase, potentially phosphorylated by Cdc28p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YCL002C |
YCL002C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPE3 |
YPR069C |
Spermidine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YDR415C |
YDR415C |
Putative aminopeptidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MDM38 |
YOL027C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MNN5 |
YJL186W |
Alpha-1,2-mannosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AIM34 |
YMR003W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COX8 |
YLR395C |
Subunit VIII of cytochrome c oxidase (Complex IV) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MIC27 |
YNL100W |
Component of the MICOS complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEX9 |
YMR018W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAU10 |
YDR542W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TRK1 |
YJL129C |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
2 |
2 |
1 |
Dosage Lethality, Dosage Rescue |
| TRK2 |
YKR050W |
Component of the Trk1p-Trk2p potassium transport system |
genetic |
2 |
2 |
1 |
Dosage Lethality, Dosage Rescue |
| MRP13 |
YGR084C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MRPL39 |
YML009C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC40 |
YDR364C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOL1 |
YNR055C |
Putative transporter in the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AXL2 |
YIL140W |
Integral plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC19 |
YKL013C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDF2 |
YDL070W |
Protein involved in transcription initiation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATP22 |
YDR350C |
Specific translational activator for the mitochondrial ATP6 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSH155 |
YMR288W |
U2-snRNP associated splicing factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARB1 |
YER036C |
ATPase of the ATP-binding cassette (ABC) family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP10 |
YDL045W-A |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOA4 |
YDR069C |
Ubiquitin hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP6 |
YBR055C |
Splicing factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MLH2 |
YLR035C |
Protein involved in mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOS4 |
YIL112W |
Subunit of the Set3 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AVT4 |
YNL101W |
Vacuolar transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HRK1 |
YOR267C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTR3 |
YLR411W |
High-affinity copper transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDH2 |
YAL061W |
Putative medium-chain alcohol dehydrogenase with similarity to BDH1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FES1 |
YBR101C |
Hsp70 (Ssa1p) nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AIM17 |
YHL021C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LAP2 |
YNL045W |
Leucyl aminopeptidase yscIV with epoxide hydrolase activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GPH1 |
YPR160W |
Glycogen phosphorylase required for the mobilization of glycogen |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FAR7 |
YFR008W |
Protein involved in recovery from pheromone-induced cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACH1 |
YBL015W |
Protein with CoA transferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEL2 |
YDR266C |
RING finger ubiquitin ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS2 |
YGL087C |
Ubiquitin-conjugating enzyme variant |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FOL2 |
YGR267C |
GTP-cyclohydrolase I, catalyzes first step in folic acid biosynthesis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLH3 |
YPL164C |
Protein involved in DNA mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAF1 |
YMR102C |
Sterol-binding beta-propeller protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DUG2 |
YBR281C |
Component of glutamine amidotransferase (GATase II) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDS1 |
YDR113C |
Securin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| LTP1 |
YPR073C |
Protein phosphotyrosine phosphatase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HUL5 |
YGL141W |
Multiubiquitin chain assembly factor (E4) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOG1 |
YHR044C |
2-deoxyglucose-6-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMI2 |
YDR516C |
Hexokinase expressed during growth with low glucose levels |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FPK1 |
YNR047W |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ICP55 |
YER078C |
Mitochondrial aminopeptidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| FMP10 |
YER182W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKI1 |
YLR133W |
Choline kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MDH3 |
YDL078C |
Peroxisomal malate dehydrogenase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MET16 |
YPR167C |
3'-phosphoadenylsulfate reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PKH1 |
YDR490C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KKQ8 |
YKL168C |
Putative serine/threonine protein kinase with unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BIT2 |
YBR270C |
Subunit of TORC2 membrane-associated complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PRS1 |
YKL181W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LAC1 |
YKL008C |
Ceramide synthase component |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ADE2 |
YOR128C |
Phosphoribosylaminoimidazole carboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| ARG81 |
YML099C |
Zinc finger transcription factor involved in arginine-responsive genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GZF3 |
YJL110C |
GATA zinc finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG19 |
YOL082W |
Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDC1 |
YML031W |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NIF3 |
YGL221C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PDR8 |
YLR266C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTL1 |
YMR180C |
RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP16 |
YDR070C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRR1 |
YKL116C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AVO2 |
YMR068W |
Component of a complex containing the Tor2p kinase and other proteins |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BLI1 |
YKL061W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MDR1 |
YGR100W |
Cytoplasmic GTPase-activating protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC31 |
YOR257W |
Calcium-binding component of the spindle pole body (SPB) half-bridge |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BNI5 |
YNL166C |
Linker protein responsible for recruitment of myosin to the bud neck |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM3 |
YEL032W |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MTR2 |
YKL186C |
mRNA transport regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BIK1 |
YCL029C |
Microtubule-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET111 |
YMR257C |
Mitochondrial translational activator specific for the COX2 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKC7 |
YDR144C |
GPI-anchored aspartyl protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
physical |
1 |
1 |
1 |
Biochemical Activity |
| BNR1 |
YIL159W |
Formin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMC5 |
YIL027C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DAL80 |
YKR034W |
Negative regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSY2 |
YLR258W |
Glycogen synthase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALY1 |
YKR021W |
Alpha arrestin, substrate of calcineurin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX11 |
YOL147C |
Peroxisomal protein required for medium-chain fatty acid oxidation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HRI1 |
YLR301W |
Protein of unknown function that interacts with Sec72p and Hrr25p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MGA1 |
YGR249W |
Protein similar to heat shock transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AZF1 |
YOR113W |
Zinc-finger transcription factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MRF1 |
YGL143C |
Mitochondrial translation release factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSB3 |
YNL293W |
Rab GTPase-activating protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MSB3 |
YNL293W |
Rab GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSB4 |
YOL112W |
GTPase-activating protein of the Ras superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPA2 |
YPR193C |
Tetrameric histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BCS1 |
YDR375C |
Protein translocase and chaperone required for Complex III assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBI2 |
YNL015W |
Cytosolic inhibitor of vacuolar proteinase B (PRB1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG10 |
YLL042C |
Conserved E2-like conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HBT1 |
YDL223C |
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX14 |
YML129C |
Mitochondrial cytochrome c oxidase (complex IV) assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ADI1 |
YMR009W |
Acireductone dioxygenease involved in methionine salvage pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDS2 |
YJL146W |
Protein involved in modulation of Ime2p activity during meiosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EMC6 |
YLL014W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP27 |
YLR454W |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIT1 |
YNR001C |
Mitochondrial citrate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP31 |
YDR533C |
Methylglyoxalase that converts methylglyoxal to D-lactate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRA1 |
YLL029W |
Protein involved in negative regulation of iron regulon transcription |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ESBP6 |
YNL125C |
Protein with similarity to monocarboxylate permeases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DSF2 |
YBR007C |
Deletion suppressor of mpt5 mutation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS5 |
YOL030W |
1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LYS20 |
YDL182W |
Homocitrate synthase isozyme and functions in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ10 |
YOL008W |
Coenzyme Q (ubiquinone) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTH1 |
YDR001C |
Neutral trehalase, degrades trehalose |
physical |
1 |
1 |
1 |
Biochemical Activity |
| KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AVT1 |
YJR001W |
Vacuolar transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PAM1 |
YDR251W |
Essential protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MTG1 |
YMR097C |
Putative GTPase peripheral to the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPY1 |
YGL067W |
NADH diphosphatase (pyrophosphatase) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NPY1 |
YGL067W |
NADH diphosphatase (pyrophosphatase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOB2 |
YPR117W |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC8 |
YJL051W |
Bud tip localized protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MBR1 |
YKL093W |
Protein involved in mitochondrial functions and stress response |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AQY3 |
YFL054C |
Putative channel-like protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CBS1 |
YDL069C |
Mitochondrial translational activator of the COB mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHO13 |
YDL236W |
Conserved phosphatase acting as a metabolite repair enzyme |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GEP5 |
YLR091W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB4 |
YLR210W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IGD1 |
YFR017C |
Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ALR2 |
YFL050C |
Probable Mg(2+) transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ATG21 |
YPL100W |
Phosphoinositide binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AVT3 |
YKL146W |
Vacuolar transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CCW22 |
YDR134C |
Cell wall protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ADD37 |
YMR184W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHO90 |
YJL198W |
Low-affinity phosphate transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PDX3 |
YBR035C |
Pyridoxine (pyridoxamine) phosphate oxidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VTC3 |
YPL019C |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TOM71 |
YHR117W |
Mitochondrial outer membrane protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STF2 |
YGR008C |
Protein involved in resistance to desiccation stress |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YMR099C |
YMR099C |
Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VMA5 |
YKL080W |
Subunit C of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SLM2 |
YNL047C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PXL1 |
YKR090W |
Protein that localizes to sites of polarized growth |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YNL284C-A |
YNL284C-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YAP1802 |
YGR241C |
Protein of the AP180 family, involved in clathrin cage assembly |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RTS3 |
YGR161C |
Putative component of the protein phosphatase type 2A complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SDL1 |
YIL167W |
Blocked reading frame otherwise encoding L-serine dehydratase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YHR112C |
YHR112C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TKL1 |
YPR074C |
Transketolase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPK3 |
YBR028C |
AGC kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPK3 |
YBR028C |
AGC kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SET5 |
YHR207C |
Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SKG1 |
YKR100C |
Transmembrane protein with a role in cell wall polymer composition |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TGL1 |
YKL140W |
Steryl ester hydrolase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPT35 |
YHR105W |
Endosomal protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SER33 |
YIL074C |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YJR056C |
YJR056C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UTR1 |
YJR049C |
ATP-NADH kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YUH1 |
YJR099W |
Ubiquitin C-terminal hydrolase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YMR196W |
YMR196W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YAK1 |
YJL141C |
Serine-threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YER010C |
YER010C |
Bifunctional HMG aldolase/oxaloacetate decarboxylase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ZRG17 |
YNR039C |
Endoplasmic reticulum zinc transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RKM4 |
YDR257C |
Ribosomal lysine methyltransferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TIP41 |
YPR040W |
Tap42p-interacting protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UBP7 |
YIL156W |
Ubiquitin-specific protease that cleaves ubiquitin-protein fusions |
physical |
1 |
1 |
1 |
Biochemical Activity |
| WHI5 |
YOR083W |
Repressor of G1 transcription |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHS2 |
YIL135C |
Regulator of septin dynamics |
physical |
1 |
1 |
1 |
Biochemical Activity |
| WTM2 |
YOR229W |
Transcriptional modulator |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YJL070C |
YJL070C |
Putative metallo-dependent hydrolase superfamily protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML037C |
YML037C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR210C |
YGR210C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YHR022C |
YHR022C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| WTM1 |
YOR230W |
Transcriptional modulator |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YLR257W |
YLR257W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RNH70 |
YGR276C |
3'-5' exoribonuclease |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YPL077C |
YPL077C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YJU3 |
YKL094W |
Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML096W |
YML096W |
Putative protein with similarity to asparagine synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SSP1 |
YHR184W |
Protein involved in the control of meiotic nuclear division |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCR023C |
YCR023C |
Vacuolar membrane protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGR266W |
YGR266W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RMD8 |
YFR048W |
Cytosolic protein required for sporulation |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SPO16 |
YHR153C |
Meiosis-specific protein involved in synaptonemal complex assembly |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YGK3 |
YOL128C |
Protein kinase related to mammalian GSK-3 glycogen synthase kinases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YKR041W |
YKR041W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZDS2 |
YML109W |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ZDS1 |
YMR273C |
Protein with a role in regulating Swe1p-dependent polarized growth |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBS1 |
YBR165W |
Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUS9 |
YDL036C |
Mitochondrial tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIP1 |
YDR422C |
One of three alternate beta-subunits of the Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDD1 |
YEL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKR104W |
YKR104W |
Putative transporter of the MRP subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNN1 |
YNL086W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIP3 |
YNL257C |
Putative sterol transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMF2 |
YHR050W |
Divalent metal ion transporter involved in manganese homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YVC1 |
YOR087W |
Vacuolar cation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPH1 |
YLR313C |
Protein involved in shmoo formation and bipolar bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL029C |
YOL029C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPK1 |
YKL126W |
S/T protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| SRB7 |
YDR308C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TFA1 |
YKL028W |
TFIIE large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TVS1 |
YCR061W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YCR090C |
YCR090C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGR237C |
YGR237C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHT1 |
YGR065C |
High-affinity plasma membrane H+-biotin (vitamin H) symporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP2 |
YNL088W |
Topoisomerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCO1 |
YBR037C |
Copper-binding protein of mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCP4 |
YCR004C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSK22 |
YCR073C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCR2 |
YDR003W |
Vacuolar ubiquitin ligase-substrate adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRG1 |
YDR065W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB5 |
YDR079C-A |
Component of RNA polymerase II general transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TVP15 |
YDR100W |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM1 |
YDR120C |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHS1 |
YDR247W |
Cytoplasmic serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URC2 |
YDR520C |
Putative Zn(II)2Cys6 motif containing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRP2 |
YER090W |
Anthranilate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFL051C |
YFL051C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RMD9 |
YGL107C |
Mitochondrial protein that controls mitochondrial gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL185C |
YGL185C |
Putative protein with sequence similar to hydroxyacid dehydrogenases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR035C |
YGR035C |
Putative protein of unknown function, potential Cdc28p substrate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYF2 |
YGR129W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QCR9 |
YGR183C |
Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TNA1 |
YGR260W |
High affinity nicotinic acid plasma membrane permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID28 |
YIL017C |
GID Complex subunit, serves as adaptor for regulatory subunit Vid24p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIR042C |
YIR042C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL206C |
YJL206C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKE4 |
YIL023C |
Zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHE2 |
YKL130C |
RNA-binding protein that binds specific mRNAs and interacts with She3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYM1 |
YLR251W |
Protein required for ethanol metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYC1 |
YOR179C |
Subunit of the APT subcomplex of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA16 |
YOR252W |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TVP38 |
YKR088C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSA3 |
YLR221C |
Protein with a likely role in ribosomal maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM9 |
YML014W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML018C |
YML018C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCH1 |
YMR034C |
Negative regulator of cytosolic calcium homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA10 |
YMR271C |
Minor orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNO4 |
YMR322C |
Possible chaperone and cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDH5 |
YOL071W |
Protein required for flavinylation of Sdh1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT4 |
YOR348C |
Proline permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUV3 |
YPL029W |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAM4 |
YPL273W |
S-adenosylmethionine-homocysteine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR268C |
YOR268C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR315W |
YMR315W |
Protein with NADP(H) oxidoreductase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGL3 |
YML118W |
3'-5' exonuclease specific for poly-A RNAs |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ENT4 |
YLL038C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ICS2 |
YBR157C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ORM1 |
YGR038W |
Protein that mediates sphingolipid homeostasis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NMT1 |
YLR195C |
N-myristoyl transferase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ISF1 |
YMR081C |
Serine-rich, hydrophilic protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DIF1 |
YLR437C |
Protein that regulates nuclear import of Rnr2p and Rnr4p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| POX1 |
YGL205W |
Fatty-acyl coenzyme A oxidase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NVJ2 |
YPR091C |
Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DGR2 |
YKL121W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DGR2 |
YKL121W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNR2 |
YKL064W |
Vacuolar membrane protein required for magnesium homeostasis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MLF3 |
YNL074C |
Serine-rich protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKP2 |
YGL059W |
Mitochondrial protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POT1 |
YIL160C |
3-ketoacyl-CoA thiolase with broad chain length specificity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KTR1 |
YOR099W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPA3 |
YEL066W |
D-Amino acid N-acetyltransferase that detoxifies D-amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COA1 |
YIL157C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COA2 |
YPL189C-A |
Cytochrome oxidase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPT1 |
YDR399W |
Dimeric hypoxanthine-guanine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIT1 |
YDR403W |
Sporulation-specific enzyme required for spore wall maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMA19 |
YLR050C |
Integral ER membrane protein involved in protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX12 |
YLR038C |
Subunit VIb of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX9 |
YDL067C |
Subunit VIIa of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OPT1 |
YJL212C |
Proton-coupled oligopeptide transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KHA1 |
YJL094C |
Putative K+/H+ antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCS6 |
YGL211W |
Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX14 |
YDR115W |
Putative mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG40 |
YOR152C |
Autophagy receptor with a role in endoplasmic reticulum degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDL2 |
YPL270W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| IZH2 |
YOL002C |
Plasma membrane receptor for plant antifungal osmotin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BER1 |
YLR412W |
Protein involved in microtubule-related processes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCV1 |
YDR019C |
T subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM33 |
YML087C |
Protein of unknown function, highly conserved across species |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFF1 |
YBR074W |
Multi-spanning vacuolar membrane protease |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MNT3 |
YIL014W |
Alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCT1 |
YKL134C |
Mitochondrial intermediate peptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET117 |
YER058W |
Assembly factor that couples heme a synthesis to complex IV assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEM4 |
YOR278W |
Uroporphyrinogen III synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXT13 |
YEL069C |
Putative transmembrane polyol transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADF1 |
YCL058W-A |
Transcriptional repressor encoded by the FYV5 antisense strand |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAU21 |
YOR394W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| PAU1 |
YJL223C |
Member of the seripauperin multigene family |
genetic |
1 |
1 |
1 |
Negative Genetic |
