| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
32 |
5 |
23 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western |
| HTA1 |
YDR225W |
Histone H2A |
physical |
13 |
3 |
11 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| HTB1 |
YDR224C |
Histone H2B |
physical |
11 |
3 |
9 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS |
| HHT1 |
YBR010W |
Histone H3 |
physical |
10 |
4 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Co-localization, Affinity Capture-Western |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
10 |
2 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
physical |
10 |
1 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
physical |
10 |
1 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
physical |
10 |
1 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
physical |
10 |
2 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| HHT2 |
YNL031C |
Histone H3 |
physical |
10 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
| CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
9 |
2 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Affinity Capture-MS |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
physical |
9 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
| PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
physical |
8 |
1 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
8 |
1 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
8 |
1 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
physical |
8 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
8 |
5 |
5 |
Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Rescue, Negative Genetic, Negative Genetic, Phenotypic Enhancement |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
physical |
8 |
3 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| HHF1 |
YBR009C |
Histone H4 |
physical |
7 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS |
| HTB2 |
YBL002W |
Histone H2B |
physical |
7 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
6 |
4 |
5 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Rescue, Phenotypic Suppression |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
6 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-localization |
| HTA2 |
YBL003C |
Histone H2A |
physical |
6 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS |
| SAN1 |
YDR143C |
Ubiquitin-protein ligase |
genetic |
6 |
3 |
4 |
Dosage Lethality, Dosage Lethality, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Synthetic Rescue |
| NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
6 |
3 |
4 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
5 |
5 |
5 |
Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue, Dosage Growth Defect, Phenotypic Enhancement |
| HHF2 |
YNL030W |
Histone H4 |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
genetic |
5 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect |
| MCM4 |
YPR019W |
Essential helicase component of heterohexameric MCM2-7 complexes |
physical |
5 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| MCM2 |
YBL023C |
Protein involved in DNA replication |
physical |
5 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| HTB1 |
YDR224C |
Histone H2B |
genetic |
4 |
4 |
4 |
Synthetic Growth Defect, Dosage Rescue, Dosage Growth Defect, Phenotypic Enhancement |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Dosage Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
4 |
3 |
2 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Dosage Lethality |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
4 |
3 |
2 |
Dosage Lethality, Dosage Lethality, Synthetic Growth Defect, Dosage Rescue |
| HHT1 |
YBR010W |
Histone H3 |
genetic |
3 |
3 |
3 |
Dosage Lethality, Synthetic Rescue, Synthetic Lethality |
| SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
| YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality |
| HHT2 |
YNL031C |
Histone H3 |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect |
| SLD5 |
YDR489W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
3 |
1 |
3 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
| SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
physical |
3 |
1 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SAN1 |
YDR143C |
Ubiquitin-protein ligase |
physical |
3 |
3 |
2 |
Two-hybrid, Affinity Capture-Western, Reconstituted Complex |
| RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
physical |
3 |
3 |
2 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS |
| CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
3 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
3 |
3 |
1 |
Synthetic Lethality, Synthetic Growth Defect, Dosage Rescue |
| YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
physical |
3 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Luminescence, Affinity Capture-Luminescence |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
physical |
3 |
2 |
1 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Lethality |
| RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
physical |
2 |
2 |
2 |
PCA, Affinity Capture-MS |
| SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Lethality |
| HHF1 |
YBR009C |
Histone H4 |
genetic |
2 |
2 |
2 |
Dosage Lethality, Synthetic Growth Defect |
| HTB2 |
YBL002W |
Histone H2B |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Dosage Rescue |
| HTA2 |
YBL003C |
Histone H2A |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression |
| CSM3 |
YMR048W |
Replication fork associated factor |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Synthetic Growth Defect |
| PHO80 |
YOL001W |
Cyclin |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Dosage Rescue |
| PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TOP1 |
YOL006C |
Topoisomerase I |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SPT6 |
YGR116W |
Nucleosome remodeling protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| TOP2 |
YNL088W |
Topoisomerase II |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| SWI6 |
YLR182W |
Transcription cofactor |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RTT106 |
YNL206C |
Histone chaperone |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
| RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| NPL3 |
YDR432W |
RNA-binding protein |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Phenotypic Enhancement |
| TFA1 |
YKL028W |
TFIIE large subunit |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
| TOA2 |
YKL058W |
TFIIA small subunit |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Lethality |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
2 |
2 |
1 |
Reconstituted Complex, Affinity Capture-Western |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Lethality |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
2 |
2 |
1 |
Dosage Lethality, Synthetic Growth Defect |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
| NFI1 |
YOR156C |
SUMO E3 ligase |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
| SIZ1 |
YDR409W |
SUMO E3 ligase |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
| POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
| NHP6A |
YPR052C |
High-mobility group (HMG) protein |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| RTT106 |
YNL206C |
Histone chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MAK16 |
YAL025C |
Essential nuclear protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIX7 |
YLL034C |
Putative ATPase of the AAA family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
physical |
1 |
1 |
1 |
PCA |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VHS1 |
YDR247W |
Cytoplasmic serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SPT6 |
YGR116W |
Nucleosome remodeling protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| TFA1 |
YKL028W |
TFIIE large subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TFA2 |
YKR062W |
TFIIE small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMC1 |
YOR052C |
AN1-type zinc finger protein, effector of proteotoxic stress response |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
physical |
1 |
1 |
1 |
Biochemical Activity |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SVF1 |
YDR346C |
Protein with a potential role in cell survival pathways |
physical |
1 |
1 |
1 |
PCA |
| YNR065C |
YNR065C |
Protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| YGK3 |
YOL128C |
Protein kinase related to mammalian GSK-3 glycogen synthase kinases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ZIP1 |
YDR285W |
Transverse filament protein of the synaptonemal complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT1 |
YFL038C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VTC2 |
YFL004W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOS4 |
YLR183C |
Putative transcription factor, contains Forkhead Associated domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS34 |
YLR240W |
Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YDR316W-B |
YDR316W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UGA2 |
YBR006W |
Succinate semialdehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TCB1 |
YOR086C |
Lipid-binding ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIM44 |
YIL022W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TUB1 |
YML085C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YMR196W |
YMR196W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YNR048W |
YNR048W |
Potential noncatalytic subunit for phospholipid translocase Dnf3p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPL150W |
YPL150W |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YHK8 |
YHR048W |
Presumed antiporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YND1 |
YER005W |
Apyrase with wide substrate specificity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT31 |
YER031C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| STB1 |
YNL309W |
Protein with role in regulation of MBF-specific transcription at Start |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAR029W |
YAR029W |
Member of DUP240 gene family but contains no transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMD2 |
YHR216W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BOI2 |
YER114C |
Protein involved in polar growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HHF2 |
YNL030W |
Histone H4 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HIF1 |
YLL022C |
Non-essential component of the HAT-B histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MCM6 |
YGL201C |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| ADA2 |
YDR448W |
Transcription coactivator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP7 |
YNL005C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MSH6 |
YDR097C |
Protein required for mismatch repair in mitosis and meiosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDS3 |
YGL197W |
Putative component of the TOR regulatory pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNH1 |
YMR234W |
Ribonuclease H1 |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT15 |
YER148W |
TATA-binding protein (TBP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUR2 |
YLR226W |
Cyclin for the Sgv1p (Bur1p) protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SPP1 |
YPL138C |
Subunit of COMPASS (Set1C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ARO4 |
YBR249C |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKH2 |
YOL100W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAS1 |
YOR101W |
GTPase involved in G-protein signaling in adenylate cyclase activation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE6 |
YPR159W |
Glucosyl hydrolase required for beta-1,6-glucan biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SGD1 |
YLR336C |
Essential nuclear protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| OPY1 |
YBR129C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NOP53 |
YPL146C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM8 |
YJR022W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIR1 |
YKR101W |
Protein involved in silencing at mating-type loci HML and HMR |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
| DCK1 |
YLR422W |
Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MPD2 |
YOL088C |
Member of the protein disulfide isomerase (PDI) family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MND2 |
YIR025W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUR1 |
YDL089W |
Protein involved in regulation of mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUT3 |
YKL015W |
Transcriptional activator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IRC6 |
YFR043C |
Clathrin coat accessory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRF1 |
YGR246C |
TFIIIB B-related factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPC10 |
YHR143W-A |
RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8B |
YER102W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO5 |
YMR109W |
One of two type I myosin motors |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MGM1 |
YOR211C |
Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IQG1 |
YPL242C |
Actin filament binding protein that enhances actin ring formation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SCO2 |
YBR024W |
Protein anchored to mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDV1 |
YJL112W |
Peripheral protein of cytosolic face of mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC107 |
YJR021C |
Protein involved in early stages of meiotic recombination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GYL1 |
YMR192W |
Putative GTPase activating protein (GAP) with a role in exocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRI1 |
YPR118W |
5'-methylthioribose-1-phosphate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| OAF1 |
YAL051W |
Oleate-activated transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL7A |
YGL076C |
Ribosomal 60S subunit protein L7A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CIT1 |
YNR001C |
Mitochondrial citrate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDP3 |
YLR455W |
Component of the NuA3b histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| JHD2 |
YJR119C |
JmjC domain family histone demethylase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| PSG1 |
YKL077W |
Protein that promotes the transport and maturation of Pma1 with Exp1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AIM45 |
YPR004C |
Putative ortholog of mammalian ETF-alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERV15 |
YBR210W |
Protein involved in export of proteins from the endoplasmic reticulum |
physical |
1 |
1 |
1 |
PCA |
| SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SPO75 |
YLL005C |
Meiosis-specific protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEL1 |
YHR035W |
Activator of Sar1p GTPase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ARA2 |
YMR041C |
NAD-dependent arabinose dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MUK1 |
YPL070W |
Guanine nucleotide exchange factor (GEF) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AQY3 |
YFL054C |
Putative channel-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RDH54 |
YBR073W |
DNA-dependent ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MSS51 |
YLR203C |
Specific translational activator for the mitochondrial COX1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG33 |
YLR356W |
Mitochondrial mitophagy-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL42A |
YNL162W |
Ribosomal 60S subunit protein L42A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GIP4 |
YAL031C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AHC2 |
YCR082W |
Component of the ADA histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEM12 |
YDR047W |
Uroporphyrinogen decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL13B |
YMR142C |
Ribosomal 60S subunit protein L13B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTR1 |
YER139C |
Dual specificity protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COQ8 |
YGL119W |
ATPase required for ubiquinone biosynthesis and respiratory growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL2B |
YIL018W |
Ribosomal 60S subunit protein L2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SPO14 |
YKR031C |
Phospholipase D |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GOT1 |
YMR292W |
Homodimeric protein that is packaged into COPII vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ERG29 |
YMR134W |
Protein of unknown function involved in ergosterol biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FAD1 |
YDL045C |
Flavin adenine dinucleotide (FAD) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATH1 |
YPR026W |
Acid trehalase required for utilization of extracellular trehalose |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HIS1 |
YER055C |
ATP phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPI8 |
YJL133C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS4 |
YOL132W |
1,3-beta-glucanosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEG2 |
YKL105C |
Eisosome component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RKR1 |
YMR247C |
RING domain E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPA10 |
YLR307C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNE1 |
YOR350C |
Protein involved in splicing Group I aI5-beta intron from COX1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUS2 |
YGL063W |
Mitochondrial tRNA:pseudouridine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MIN3 |
YMR182W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
