Standard name Systematic name Name description Description
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance
Visualize the interactome of SRB2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm NaN 0.619 0.835
Mito NaN 0.476 NaN
Vac/Vac Memb NaN 0.143 0.063

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 1720

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SRB2 4 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SRB4 YER022W Subunit of the RNA polymerase II mediator complex physical 16 4 15 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex physical 14 5 12 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Co-purification, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 7 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 7 2 4 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex physical 6 4 6 Affinity Capture-MS, Co-purification, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex physical 5 3 5 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS
MED7 YOL135C Subunit of the RNA polymerase II mediator complex physical 5 2 5 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 5 3 4 Negative Genetic, Negative Genetic, Synthetic Rescue, Synthetic Growth Defect, Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 5 2 4 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 4 4 4 Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Growth Defect
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex physical 4 3 4 Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
SWC5 YBR231C Component of the SWR1 complex genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 4 2 3 Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 4 2 3 Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 3 3 3 Synthetic Rescue, Phenotypic Enhancement, Negative Genetic
RPB4 YJL140W RNA polymerase II subunit B32 genetic 3 2 3 Positive Genetic, Synthetic Lethality, Synthetic Lethality
MED2 YDL005C Subunit of the RNA polymerase II mediator complex physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
MED6 YHR058C Subunit of the RNA polymerase II mediator complex physical 3 2 3 Affinity Capture-Western, Co-purification, Co-purification
ELP3 YPL086C Subunit of Elongator complex genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Positive Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Positive Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
VPS21 YOR089C Endosomal Rab family GTPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 3 1 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HPR1 YDR138W Subunit of THO/TREX complexes genetic 3 2 2 Phenotypic Enhancement, Synthetic Rescue, Synthetic Rescue
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 3 2 2 Positive Genetic, Negative Genetic, Negative Genetic
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality
LSM6 YDR378C Lsm (Like Sm) protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YLL058W YLL058W Putative protein of unknown function with similarity to Str2p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
EGD1 YPL037C Subunit beta1 of the nascent polypeptide-associated complex (NAC) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
REX2 YLR059C 3'-5' RNA exonuclease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ATC1 YDR184C Nuclear protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MCY1 YGR012W Putative cysteine synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 2 2 2 Affinity Capture-Western, Co-purification
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 2 2 2 Negative Genetic, Positive Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 2 2 2 Positive Genetic, Phenotypic Suppression
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 2 2 2 Positive Genetic, Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 2 2 2 Negative Genetic, Positive Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
ADA2 YDR448W Transcription coactivator genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 2 2 2 Positive Genetic, Negative Genetic
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Phenotypic Suppression
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) physical 2 2 2 Co-purification, Affinity Capture-Western
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 2 2 2 Negative Genetic, Positive Genetic
CTF4 YPR135W Chromatin-associated protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 2 1 2 Positive Genetic, Positive Genetic
SRB4 YER022W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 1 2 Negative Genetic, Negative Genetic
SSD1 YDR293C Translational repressor genetic 2 1 2 Negative Genetic, Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Positive Genetic, Positive Genetic
UTR4 YEL038W Protein with sequence similarity to acireductone synthases genetic 2 1 2 Negative Genetic, Negative Genetic
YND1 YER005W Apyrase with wide substrate specificity genetic 2 1 2 Negative Genetic, Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 2 1 2 Negative Genetic, Negative Genetic
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 2 1 2 Negative Genetic, Negative Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 2 1 2 Negative Genetic, Negative Genetic
TAT2 YOL020W High affinity tryptophan and tyrosine permease genetic 2 1 2 Negative Genetic, Negative Genetic
TKL1 YPR074C Transketolase genetic 2 1 2 Negative Genetic, Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 2 1 2 Negative Genetic, Negative Genetic
TEX1 YNL253W Protein involved in mRNA export genetic 2 1 2 Negative Genetic, Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 2 1 2 Negative Genetic, Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 2 1 2 Positive Genetic, Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 1 2 Negative Genetic, Negative Genetic
BDF2 YDL070W Protein involved in transcription initiation genetic 2 1 2 Negative Genetic, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 2 1 2 Positive Genetic, Positive Genetic
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 2 1 2 Co-purification, Co-purification
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 1 2 Negative Genetic, Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 1 2 Negative Genetic, Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 2 1 2 Negative Genetic, Negative Genetic
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway genetic 2 1 2 Positive Genetic, Positive Genetic
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 2 1 2 Negative Genetic, Negative Genetic
DEF1 YKL054C RNAPII degradation factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 2 1 2 Negative Genetic, Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 2 1 2 Negative Genetic, Negative Genetic
SAC3 YDR159W mRNA export factor genetic 2 1 2 Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
PDR17 YNL264C Phosphatidylinositol transfer protein (PITP) genetic 2 1 2 Negative Genetic, Negative Genetic
SCO2 YBR024W Protein anchored to mitochondrial inner membrane genetic 2 1 2 Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 2 1 2 Negative Genetic, Negative Genetic
LCB5 YLR260W Minor sphingoid long-chain base kinase genetic 2 1 2 Negative Genetic, Negative Genetic
NPR1 YNL183C Protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) genetic 2 1 2 Negative Genetic, Negative Genetic
AAD16 YFL057C Putative aryl alcohol dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 2 1 2 Positive Genetic, Positive Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 2 1 2 Negative Genetic, Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 2 2 1 Positive Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 2 2 1 Dosage Rescue, Synthetic Rescue
YJL213W YJL213W Protein of unknown function that may interact with ribosomes genetic 2 1 1 Negative Genetic, Negative Genetic
YKR018C YKR018C Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
HHT1 YBR010W Histone H3 genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RPA14 YDR156W RNA polymerase I subunit A14 genetic 2 1 1 Negative Genetic, Negative Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 1 1 Negative Genetic, Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 2 1 1 Negative Genetic, Negative Genetic
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 2 1 1 Negative Genetic, Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 2 1 1 Negative Genetic, Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SER3 YER081W 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
MSA1 YOR066W Activator of G1-specific transcription factors MBF and SBF regulation 1 1 1 DNA to cDNA expression microarray evidence
TMC1 YOR052C AN1-type zinc finger protein, effector of proteotoxic stress response regulation 1 1 1 DNA to cDNA expression microarray evidence
AKR2 YOR034C Ankyrin repeat-containing protein regulation 1 1 1 DNA to cDNA expression microarray evidence
ARG1 YOL058W Arginosuccinate synthetase regulation 1 1 1 DNA to cDNA expression microarray evidence
CLB1 YGR108W B-type cyclin involved in cell cycle progression regulation 1 1 1 DNA to cDNA expression microarray evidence
CHA1 YCL064C Catabolic L-serine (L-threonine) deaminase regulation 1 1 1 DNA to cDNA expression microarray evidence
ASP3-1 YLR155C Cell-wall L-asparaginase II involved in asparagine catabolism regulation 1 1 1 DNA to cDNA expression microarray evidence
ASP3-2 YLR157C Cell-wall L-asparaginase II involved in asparagine catabolism regulation 1 1 1 DNA to cDNA expression microarray evidence
ASP3-3 YLR158C Cell-wall L-asparaginase II involved in asparagine catabolism regulation 1 1 1 DNA to cDNA expression microarray evidence
ASP3-4 YLR160C Cell-wall L-asparaginase II involved in asparagine catabolism regulation 1 1 1 DNA to cDNA expression microarray evidence
TIR3 YIL011W Cell wall mannoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
YGP1 YNL160W Cell wall-related secretory glycoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex regulation 1 1 1 DNA to cDNA expression microarray evidence
DSE2 YHR143W Daughter cell-specific secreted protein with similarity to glucanases regulation 1 1 1 DNA to cDNA expression microarray evidence
YDL023C YDL023C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR041W YLR041W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR232W YLR232W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
COS10 YNR075W Endosomal protein involved in turnover of plasma membrane proteins regulation 1 1 1 DNA to cDNA expression microarray evidence
EGT2 YNL327W Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase regulation 1 1 1 DNA to cDNA expression microarray evidence
YRF1-6 YNL339C Helicase encoded by the Y' element of subtelomeric regions regulation 1 1 1 DNA to cDNA expression microarray evidence
PTR2 YKR093W Integral membrane peptide transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
TIP1 YBR067C Major cell wall mannoprotein with possible lipase activity regulation 1 1 1 DNA to cDNA expression microarray evidence
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall regulation 1 1 1 DNA to cDNA expression microarray evidence
FIT3 YOR383C Mannoprotein that is incorporated into the cell wall regulation 1 1 1 DNA to cDNA expression microarray evidence
CUP1-1 YHR053C Metallothionein regulation 1 1 1 DNA to cDNA expression microarray evidence
MMF1 YIL051C Mitochondrial protein required for transamination of isoleucine regulation 1 1 1 DNA to cDNA expression microarray evidence
YHB1 YGR234W Nitric oxide oxidoreductase regulation 1 1 1 DNA to cDNA expression microarray evidence
TRF5 YNL299W Non-canonical poly(A) polymerase regulation 1 1 1 DNA to cDNA expression microarray evidence
MAK31 YCR020C-A Non-catalytic subunit of N-terminal acetyltransferase of the NatC type regulation 1 1 1 DNA to cDNA expression microarray evidence
PHO11 YAR071W One of three repressible acid phosphatases regulation 1 1 1 DNA to cDNA expression microarray evidence
PHO12 YHR215W One of three repressible acid phosphatases regulation 1 1 1 DNA to cDNA expression microarray evidence
MCH5 YOR306C Plasma membrane riboflavin transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
STP4 YDL048C Protein containing a Kruppel-type zinc-finger domain regulation 1 1 1 DNA to cDNA expression microarray evidence
DIA1 YMR316W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
RRG9 YNL213C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR162W YLR162W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
COX19 YLL018C-A Protein required for cytochrome c oxidase assembly regulation 1 1 1 DNA to cDNA expression microarray evidence
YER189W YER189W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR385W YOR385W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YNL146W YNL146W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
RRT15 YLR162W-A Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOL014W YOL014W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR159W YLR159W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p regulation 1 1 1 DNA to cDNA expression microarray evidence
RPL28 YGL103W Ribosomal 60S subunit protein L28 regulation 1 1 1 DNA to cDNA expression microarray evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Positive Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Co-purification
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Reconstituted Complex
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Synthetic Lethality
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Positive Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Negative Genetic
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
NOP16 YER002W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Positive Genetic
RPL38 YLR325C Ribosomal 60S subunit protein L38 genetic 1 1 1 Positive Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
SAP1 YER047C Putative ATPase of the AAA family genetic 1 1 1 Negative Genetic
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 1 1 1 Negative Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) genetic 1 1 1 Positive Genetic
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs genetic 1 1 1 Negative Genetic
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Positive Genetic
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Positive Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Positive Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
RRP43 YCR035C Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
RSC58 YLR033W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes physical 1 1 1 Affinity Capture-MS
TFB4 YPR056W Subunit of TFIIH complex physical 1 1 1 Co-purification
TFA2 YKR062W TFIIE small subunit physical 1 1 1 Co-purification
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit physical 1 1 1 Co-purification
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 Co-purification
YPL216W YPL216W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Co-purification
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Growth Defect
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Negative Genetic
UBC11 YOR339C Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Positive Genetic
YPL113C YPL113C Glyoxylate reductase genetic 1 1 1 Positive Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Positive Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Positive Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Positive Genetic
VPS75 YNL246W NAP family histone chaperone genetic 1 1 1 Positive Genetic
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
VID24 YBR105C GID Complex regulatory subunit genetic 1 1 1 Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Positive Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Negative Genetic
YOR062C YOR062C Protein of unknown function genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Positive Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 1 1 1 Positive Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Positive Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Positive Genetic
YAL064W YAL064W Protein of unknown function genetic 1 1 1 Positive Genetic
YBL008W-A YBL008W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Positive Genetic
YDL114W YDL114W Putative short-chain dehydrogenase/reductase genetic 1 1 1 Positive Genetic
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
YDR169C-A YDR169C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
TYW3 YGL050W tRNA methyltransferase required for synthesis of wybutosine genetic 1 1 1 Positive Genetic
YJL047C-A YJL047C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
YLR159C-A YLR159C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
YLR363W-A YLR363W-A Protein of unknown function genetic 1 1 1 Positive Genetic
YMR155W YMR155W Putative protein of unknown function genetic 1 1 1 Positive Genetic
YMR160W YMR160W Protein of unknown function genetic 1 1 1 Positive Genetic
YMR175W-A YMR175W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
URK1 YNR012W Uridine/cytidine kinase genetic 1 1 1 Positive Genetic
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Positive Genetic
SSO1 YPL232W Plasma membrane t-SNARE genetic 1 1 1 Positive Genetic
THI21 YPL258C Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase genetic 1 1 1 Positive Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
TEF1 YPR080W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
SRB7 YDR308C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
UTR5 YEL035C Protein of unknown function genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
TFA1 YKL028W TFIIE large subunit genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Negative Genetic
YAL037C-A YAL037C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
YAR035C-A YAR035C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YPK3 YBR028C AGC kinase genetic 1 1 1 Negative Genetic
YBR182C-A YBR182C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDL124W YDL124W NADPH-dependent alpha-keto amide reductase genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
TMN2 YDR107C Protein with a role in cellular adhesion and filamentous growth genetic 1 1 1 Negative Genetic
SSF2 YDR312W Protein required for ribosomal large subunit maturation genetic 1 1 1 Negative Genetic
THI74 YDR438W Mitochondrial transporter repressible by thiamine genetic 1 1 1 Negative Genetic
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
YER078W-A YER078W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TPN1 YGL186C Plasma membrane pyridoxine (vitamin B6) transporter genetic 1 1 1 Negative Genetic
YGR161W-C YGR161W-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Negative Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
YIL046W-A YIL046W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YJR124C YJR124C Putative protein of unknown function genetic 1 1 1 Negative Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 1 1 1 Negative Genetic
UCC1 YLR224W F-box protein and component of SCF ubiquitin ligase complexes genetic 1 1 1 Negative Genetic
YLR464W YLR464W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YML002W YML002W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) genetic 1 1 1 Negative Genetic
YNL040W YNL040W Protein of unknown function genetic 1 1 1 Negative Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
YOL159C-A YOL159C-A Protein of unknown function genetic 1 1 1 Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIR2 YOR010C Putative cell wall mannoprotein genetic 1 1 1 Negative Genetic
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
YPL068C YPL068C Protein of unknown function genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Positive Genetic
PRP40 YKL012W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Synthetic Growth Defect
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Positive Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
PRE8 YML092C Alpha 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Lethality
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
HGH1 YGR187C Chaperone protein for translation factor eEF2 genetic 1 1 1 Negative Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Positive Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Synthetic Growth Defect
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
CAR1 YPL111W Arginase, catabolizes arginine to ornithine and urea genetic 1 1 1 Negative Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p genetic 1 1 1 Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Rescue
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Positive Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Positive Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Positive Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 1 1 1 Reconstituted Complex
HHF1 YBR009C Histone H4 genetic 1 1 1 Positive Genetic
HHF2 YNL030W Histone H4 physical 1 1 1 Reconstituted Complex
HTB2 YBL002W Histone H2B genetic 1 1 1 Negative Genetic
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 1 1 1 Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
LSM2 YBL026W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LUC7 YDL087C Essential protein associated with the U1 snRNP complex genetic 1 1 1 Negative Genetic
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) genetic 1 1 1 Negative Genetic
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
MED11 YMR112C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Negative Genetic
MRPL19 YNL185C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Rescue
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Growth Defect
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities genetic 1 1 1 Negative Genetic
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Lethality
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Lethality
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
PRP28 YDR243C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
PRP31 YGR091W Splicing factor genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Positive Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NUT2 YPR168W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Negative Genetic
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Phenotypic Enhancement
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 1 1 1 Synthetic Lethality
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
DUG1 YFR044C Cys-Gly metallo-di-peptidase genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E physical 1 1 1 Affinity Capture-MS
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
PRP42 YDR235W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex genetic 1 1 1 Negative Genetic
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes physical 1 1 1 Affinity Capture-Western
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Positive Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Positive Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Positive Genetic
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Lethality
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
PNO1 YOR145C Essential nucleolar protein required for pre-18S rRNA processing genetic 1 1 1 Negative Genetic
RRP12 YPL012W Protein required for export of the ribosomal subunits genetic 1 1 1 Negative Genetic
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Positive Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Negative Genetic
HTB1 YDR224C Histone H2B physical 1 1 1 Reconstituted Complex
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
SEC53 YFL045C Phosphomannomutase genetic 1 1 1 Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Negative Genetic
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway genetic 1 1 1 Positive Genetic
LIA1 YJR070C Deoxyhypusine hydroxylase genetic 1 1 1 Synthetic Growth Defect
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III genetic 1 1 1 Negative Genetic
RNQ1 YCL028W [PIN(+)] prion physical 1 1 1 Affinity Capture-Western
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Positive Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
RAD18 YCR066W E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Positive Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Synthetic Growth Defect
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Synthetic Lethality
RAD24 YER173W Checkpoint protein genetic 1 1 1 Negative Genetic
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome genetic 1 1 1 Positive Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Positive Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly physical 1 1 1 Co-purification
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Positive Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
NOP53 YPL146C Nucleolar protein genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Phenotypic Suppression
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Positive Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Positive Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Dosage Rescue
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
RNH203 YLR154C Ribonuclease H2 subunit genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Lethality
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
GLG2 YJL137C Glycogenin glucosyltransferase genetic 1 1 1 Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Positive Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Positive Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Positive Genetic
MSN5 YDR335W Karyopherin genetic 1 1 1 Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Positive Genetic
PCL9 YDL179W Cyclin genetic 1 1 1 Negative Genetic
IKS1 YJL057C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation genetic 1 1 1 Negative Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Phenotypic Suppression
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Positive Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 1 1 1 Negative Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Positive Genetic
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Positive Genetic
NFI1 YOR156C SUMO E3 ligase genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Positive Genetic
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Positive Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Positive Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Positive Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Negative Genetic
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
FIG4 YNL325C Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase genetic 1 1 1 Negative Genetic
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes physical 1 1 1 Affinity Capture-Western
HAP4 YKL109W Transcription factor genetic 1 1 1 Negative Genetic
PRM8 YGL053W Pheromone-regulated protein genetic 1 1 1 Negative Genetic
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Negative Genetic
SIL1 YOL031C Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p genetic 1 1 1 Negative Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
SML1 YML058W Ribonucleotide reductase inhibitor genetic 1 1 1 Negative Genetic
SCO1 YBR037C Copper-binding protein of mitochondrial inner membrane genetic 1 1 1 Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Positive Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
REC114 YMR133W Protein involved in early stages of meiotic recombination genetic 1 1 1 Positive Genetic
LSB5 YCL034W Protein involved in membrane-trafficking events at plasma membrane genetic 1 1 1 Negative Genetic
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
SNZ1 YMR096W Subunit of a two-component pyridoxal-5'-phosphate synthase genetic 1 1 1 Negative Genetic
ORC5 YNL261W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
CCH1 YGR217W Voltage-gated high-affinity calcium channel genetic 1 1 1 Negative Genetic
GGA1 YDR358W Golgi-localized protein with homology to gamma-adaptin genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
ENV11 YGR071C Protein proposed to be involved in vacuolar functions genetic 1 1 1 Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Positive Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Positive Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SNU13 YEL026W RNA binding protein genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Positive Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Positive Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
ILV6 YCL009C Regulatory subunit of acetolactate synthase genetic 1 1 1 Negative Genetic
CRG1 YHR209W S-AdoMet-dependent methyltransferase involved in lipid homeostasis genetic 1 1 1 Synthetic Growth Defect
QDR3 YBR043C Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Negative Genetic
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p genetic 1 1 1 Negative Genetic
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Negative Genetic
CIT1 YNR001C Mitochondrial citrate synthase genetic 1 1 1 Negative Genetic
ASF2 YDL197C Anti-silencing protein genetic 1 1 1 Negative Genetic
RUP1 YOR138C Protein that regulates ubiquitination of Rsp5p genetic 1 1 1 Negative Genetic
BSC6 YOL137W Protein of unknown function with 8 putative transmembrane segments genetic 1 1 1 Positive Genetic
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Positive Genetic
CUE1 YMR264W Ubiquitin-binding protein genetic 1 1 1 Negative Genetic
PBP4 YDL053C Pbp1p binding protein genetic 1 1 1 Negative Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 1 1 1 Negative Genetic
IRC22 YEL001C Protein of unknown function genetic 1 1 1 Negative Genetic
ISD11 YER048W-A Cysteine desulfurase (Nfs1p) activator genetic 1 1 1 Positive Genetic
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes genetic 1 1 1 Negative Genetic
BAR1 YIL015W Aspartyl protease secreted to periplasmic space of mating type a cell genetic 1 1 1 Negative Genetic
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Positive Genetic
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
LOT6 YLR011W FMN-dependent NAD(P)H:quinone reductase genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Positive Genetic
GTT3 YEL017W Protein of unknown function may be involved in glutathione metabolism genetic 1 1 1 Positive Genetic
MRPS12 YNR036C Mitochondrial protein genetic 1 1 1 Negative Genetic
CSS1 YIL169C Protein of unknown function, secreted when constitutively expressed genetic 1 1 1 Negative Genetic
ISM1 YPL040C Mitochondrial isoleucyl-tRNA synthetase genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
CUP9 YPL177C Homeodomain-containing transcriptional repressor genetic 1 1 1 Negative Genetic
PFK26 YIL107C 6-phosphofructo-2-kinase genetic 1 1 1 Negative Genetic
RPL12A YEL054C Ribosomal 60S subunit protein L12A genetic 1 1 1 Positive Genetic
BSC2 YDR275W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Positive Genetic
NVJ3 YDR179W-A Protein with a potential role in tethering ER and vacuoles genetic 1 1 1 Negative Genetic
RPL4B YDR012W Ribosomal 60S subunit protein L4B genetic 1 1 1 Negative Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
RPL35B YDL136W Ribosomal 60S subunit protein L35B genetic 1 1 1 Positive Genetic
RPL26A YLR344W Ribosomal 60S subunit protein L26A genetic 1 1 1 Positive Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation genetic 1 1 1 Negative Genetic
CAB1 YDR531W Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase genetic 1 1 1 Negative Genetic
CMR3 YPR013C Putative zinc finger protein genetic 1 1 1 Negative Genetic
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Positive Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
DGR2 YKL121W Protein of unknown function genetic 1 1 1 Positive Genetic
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 1 1 1 Synthetic Lethality
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
SMF1 YOL122C Divalent metal ion transporter genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Positive Genetic
ALO1 YML086C D-Arabinono-1,4-lactone oxidase genetic 1 1 1 Negative Genetic
PSR2 YLR019W Putative plasma membrane phosphatase genetic 1 1 1 Negative Genetic
COA1 YIL157C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
ITR1 YDR497C Myo-inositol transporter genetic 1 1 1 Negative Genetic
COS1 YNL336W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
PIN2 YOR104W Exomer-dependent cargo protein genetic 1 1 1 Positive Genetic
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Positive Genetic
MSN1 YOL116W Transcriptional activator genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Positive Genetic
GPC1 YGR149W Glycerophosphocholine acyltransferase (GPCAT) genetic 1 1 1 Negative Genetic
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
FCY22 YER060W-A Putative purine-cytosine permease genetic 1 1 1 Negative Genetic
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
RMD8 YFR048W Cytosolic protein required for sporulation genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
RCE1 YMR274C Type II CAAX prenyl protease genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Positive Genetic
PBI1 YPL272C Putative protein of unknown function genetic 1 1 1 Positive Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Positive Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
MAM3 YOL060C Protein involved in magnesium homeostasis genetic 1 1 1 Negative Genetic
CMI7 YIL002W-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Positive Genetic
COX5B YIL111W Subunit Vb of cytochrome c oxidase genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
CYT2 YKL087C Cytochrome c1 heme lyase genetic 1 1 1 Negative Genetic
ERG12 YMR208W Mevalonate kinase genetic 1 1 1 Negative Genetic
MCO32 YGR053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Negative Genetic
AVT7 YIL088C Vacuolar amino acid transporter genetic 1 1 1 Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
GUP2 YPL189W Probable membrane protein genetic 1 1 1 Negative Genetic
SEO1 YAL067C Putative permease genetic 1 1 1 Negative Genetic
ATX2 YOR079C Golgi membrane protein involved in manganese homeostasis genetic 1 1 1 Negative Genetic
PKP1 YIL042C Mitochondrial protein kinase genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Positive Genetic
COA6 YMR244C-A Protein involved in cytochrome c oxidase (Complex IV) assembly genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic
RRG9 YNL213C Protein of unknown function genetic 1 1 1 Negative Genetic
AIM24 YJR080C Protein with a role in determining mitochondrial architecture genetic 1 1 1 Negative Genetic
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Negative Genetic
NGL1 YOL042W Putative endonuclease genetic 1 1 1 Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Positive Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
MRX10 YDR282C Mitochondrial inner membrane protein of unknown function genetic 1 1 1 Negative Genetic
IDP2 YLR174W Cytosolic NADP-specific isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
MRX20 YFR045W Putative mitochondrial transport protein genetic 1 1 1 Negative Genetic
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Negative Genetic
SPE4 YLR146C Spermine synthase genetic 1 1 1 Negative Genetic
SAM4 YPL273W S-adenosylmethionine-homocysteine methyltransferase genetic 1 1 1 Negative Genetic
RCF3 YBR255C-A Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Negative Genetic
PET20 YPL159C Mitochondrial protein genetic 1 1 1 Negative Genetic
RSM26 YJR101W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
FRE7 YOL152W Putative ferric reductase with similarity to Fre2p genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Positive Genetic
SPO24 YPR036W-A Small (67 amino acids) protein involved in sporulation genetic 1 1 1 Positive Genetic
SPS22 YCL048W Protein of unknown function genetic 1 1 1 Negative Genetic
SPO23 YBR250W Protein of unknown function genetic 1 1 1 Positive Genetic