| MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
5 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
4 |
3 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality |
| HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BLI1 |
YKL061W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
4 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
4 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SNN1 |
YNL086W |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| DCR2 |
YLR361C |
Protein phosphatase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
3 |
1 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GDT1 |
YBR187W |
Calcium and manganese transporter with higher affinity for Ca2+ |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CNL1 |
YDR357C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ERP5 |
YHR110W |
Protein with similarity to Emp24p and Erv25p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SVF1 |
YDR346C |
Protein with a potential role in cell survival pathways |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MYG1 |
YER156C |
Protein involved in mitochondrial function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| VPS68 |
YOL129W |
Vacuolar membrane protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
| CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
| RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ADH3 |
YMR083W |
Mitochondrial alcohol dehydrogenase isozyme III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ECM21 |
YBL101C |
Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BLS1 |
YLR408C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YND1 |
YER005W |
Apyrase with wide substrate specificity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPI1 |
YFR003C |
Regulatory subunit of the type I protein phosphatase (PP1) Glc7p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TMA22 |
YJR014W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPT7 |
YML001W |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MME1 |
YMR166C |
Transporter of the mitochondrial inner membrane that exports magnesium |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RCN2 |
YOR220W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAX1 |
YOR301W |
Protein involved in establishing bud site selection |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TIP41 |
YPR040W |
Tap42p-interacting protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PMC1 |
YGL006W |
Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDS22 |
YKL193C |
Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BIT61 |
YJL058C |
Subunit of TORC2 membrane-associated complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| VHC1 |
YBR235W |
Vacuolar membrane cation-chloride cotransporter (CCC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YMD8 |
YML038C |
Putative nucleotide sugar transporter |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YPQ1 |
YOL092W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TOS1 |
YBR162C |
Covalently-bound cell wall protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| AIM32 |
YML050W |
2Fe-2S mitochondrial protein involved in redox quality control |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHL4 |
YDR254W |
Outer kinetochore protein required for chromosome stability |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AMN1 |
YBR158W |
Modulator of cell separation and mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAR1 |
YHR089C |
Protein component of the H/ACA snoRNP pseudouridylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCA4 |
YJL033W |
DEAD box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG18 |
YFR021W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASR1 |
YPR093C |
Ubiquitin ligase that modifies and regulates RNA Pol II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXG1 |
YLR300W |
Major exo-1,3-beta-glucanase of the cell wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG39 |
YLR312C |
Transmembrane receptor with a role in nucleophagy |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVO2 |
YMR068W |
Component of a complex containing the Tor2p kinase and other proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC9 |
YLR102C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CQD1 |
YPL109C |
UbiB family mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENT1 |
YDL161W |
Epsin-like protein involved in endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACM1 |
YPL267W |
Pseudosubstrate inhibitor of the APC/C |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GDH3 |
YAL062W |
NADP(+)-dependent glutamate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCC1 |
YLR220W |
Vacuolar Fe2+/Mn2+ transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CNN1 |
YFR046C |
Kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATX1 |
YNL259C |
Cytosolic copper metallochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSH1 |
YBR161W |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAA1 |
YLR088W |
Subunit of the GPI:protein transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP33 |
YOR391C |
Possible chaperone and cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DGR2 |
YKL121W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAP2 |
YHR028C |
Dipeptidyl aminopeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD2 |
YKL018W |
Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDI1 |
YDL135C |
Rho GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIP1 |
YOR330C |
Mitochondrial DNA polymerase gamma |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX32 |
YBR168W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMF1 |
YOL122C |
Divalent metal ion transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCE101 |
YJL205C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC3 |
YLL004W |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCS4 |
YLR272C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCD5 |
YOR329C |
Protein required for normal actin organization and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YBR220C |
YBR220C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PCL6 |
YER059W |
Pho85p cyclin of the Pho80p subfamily |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RCE1 |
YMR274C |
Type II CAAX prenyl protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB7 |
YDR308C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS21 |
YEL019C |
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPP1 |
YGR198W |
Cargo-transport protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QNS1 |
YHR074W |
Glutamine-dependent NAD(+) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHS1 |
YJL097W |
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA6 |
YKL024C |
Uridylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRI2 |
YKL045W |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF11 |
YMR260C |
Translation initiation factor eIF1A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RKI1 |
YOR095C |
Ribose-5-phosphate ketol-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SME1 |
YOR159C |
Core Sm protein Sm E |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMP1 |
YBR182C |
MADS-box transcription factor involved in osmotic stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIC12 |
YBR262C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR298C-A |
YBR298C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB17 |
YDL146W |
Protein involved in the regulation of endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB5 |
YDR079C-A |
Component of RNA polymerase II general transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMS1 |
YDR105C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR2 |
YDR297W |
Sphinganine C4-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNX41 |
YDR425W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE2 |
YDR483W |
Alpha1,2-mannosyltransferase of the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM28 |
YDR494W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ITR1 |
YDR497C |
Myo-inositol transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN1 |
YER001W |
Alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER152C |
YER152C |
Protein with 2-aminoadipate transaminase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YFL012W |
YFL012W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN5 |
YJL186W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR149W |
YJR149W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTA1 |
YLR181C |
Multivesicular body (MVB) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR407W |
YLR407W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR210C |
YGR210C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHL008C |
YHL008C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR054C |
YHR054C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIM1 |
YIL123W |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB3 |
YJL134W |
Long-chain base-1-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JSN1 |
YJR091C |
Member of the Puf family of RNA-binding proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMT4 |
YJR143C |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL075C |
YKL075C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LMO1 |
YLL007C |
Homolog of mammalian ELMO (Engulfment and celL MOtility) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL056C |
YLL056C |
NADH-dependent aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRL2 |
YLR082C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR264C-A |
YLR264C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML037C |
YML037C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YNL042W-B |
YNL042W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIS1 |
YNL078W |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR17 |
YNL264C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIN2 |
YOR104W |
Exomer-dependent cargo protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTC5 |
YOR118W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR365C |
YOR365C |
Putative protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR381W-A |
YOR381W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX25 |
YPL112C |
Peripheral peroxisomal membrane peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ODC1 |
YPL134C |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MLH3 |
YPL164C |
Protein involved in DNA mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRE1 |
YPL176C |
Transferrin receptor-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAU22 |
YPL282C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NVJ2 |
YPR091C |
Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM3 |
YDL112W |
2'-O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA6 |
YDR067C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OXR1 |
YPL196W |
Protein involved in regulation of vacuolar V-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS1 |
YDR096W |
Histone demethylase and transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPD1 |
YGR247W |
Cyclic nucleotide phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS3 |
YLR094C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPC25 |
YPL107W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG8 |
YMR220W |
Phosphomevalonate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AQY1 |
YPR192W |
Spore-specific water channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FSH1 |
YHR049W |
Lysophospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNA4 |
YBL098W |
Kynurenine 3-monooxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV12 |
YOR183W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
