Standard name Systematic name Name description Description
PHO85 YPL031C Cyclin-dependent kinase Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation
Visualize the interactome of PHO85
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.357 0.605 0.277
Nucleus 0.116 0.161 0.330
Vac/Vac Memb 0.688 0.605 0.573

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 6160

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PHO85 8 5 0 1 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 15 2 14 Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor physical 15 5 12 Affinity Capture-MS, Two-hybrid, Two-hybrid, Biochemical Activity, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Reconstituted Complex, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Biochemical Activity
PHO80 YOL001W Cyclin physical 11 6 10 Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
PCL7 YIL050W Pho85p cyclin of the Pho80p subfamily physical 11 4 8 Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS
PCL10 YGL134W Pho85p cyclin physical 9 5 7 Two-hybrid, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Co-crystal Structure
PCL8 YPL219W Cyclin physical 9 3 7 Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS
PCL6 YER059W Pho85p cyclin of the Pho80p subfamily physical 8 3 7 Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase physical 7 1 7 Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p physical 7 5 6 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Reconstituted Complex
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 6 4 6 Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Dosage Lethality, Synthetic Growth Defect, Dosage Lethality
GSY2 YLR258W Glycogen synthase physical 6 4 5 Biochemical Activity, Biochemical Activity, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Reconstituted Complex
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p physical 6 4 4 Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-MS
PCL9 YDL179W Cyclin physical 5 3 4 Two-hybrid, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-MS
BNI1 YNL271C Formin genetic 4 3 4 Synthetic Lethality, Synthetic Growth Defect, Dosage Lethality, Synthetic Lethality
SLT2 YHR030C Serine/threonine MAP kinase genetic 4 2 4 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) physical 4 2 4 Affinity Capture-MS, Biochemical Activity, Biochemical Activity, Biochemical Activity
PCL5 YHR071W Cyclin physical 4 4 3 Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Biochemical Activity
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 4 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
WHI5 YOR083W Repressor of G1 transcription genetic 4 4 2 Dosage Growth Defect, Phenotypic Enhancement, Dosage Rescue, Dosage Lethality
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 3 2 3 Synthetic Lethality, Dosage Lethality, Synthetic Lethality
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Dosage Lethality
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
SNF1 YDR477W AMP-activated S/T protein kinase genetic 3 2 3 Synthetic Lethality, Synthetic Rescue, Synthetic Rescue
DMA1 YHR115C Ubiquitin-protein ligase (E3) physical 3 2 3 Biochemical Activity, Biochemical Activity, Affinity Capture-Western
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
EFR3 YMR212C Protein required for Stt4-containing PI kinase complex localization genetic 3 1 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 3 3 2 Dosage Lethality, Phenotypic Enhancement, Synthetic Lethality
PAP1 YKR002W Poly(A) polymerase physical 3 2 2 Affinity Capture-Western, Two-hybrid, Two-hybrid
GSP1 YLR293C Ran GTPase physical 3 2 2 Biochemical Activity, Biochemical Activity, Reconstituted Complex
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p physical 3 2 2 Two-hybrid, Reconstituted Complex, Two-hybrid
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 3 1 2 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality
OPI1 YHL020C Transcriptional regulator of a variety of genes physical 3 2 1 Reconstituted Complex, Two-hybrid, Two-hybrid
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint physical 2 2 2 Biochemical Activity, PCA
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients physical 2 2 2 Affinity Capture-MS, Biochemical Activity
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) physical 2 2 2 Affinity Capture-MS, Biochemical Activity
RPN10 YHR200W Proteasome polyubiquitin receptor physical 2 2 2 Affinity Capture-MS, Biochemical Activity
PRR1 YKL116C Serine/threonine protein kinase physical 2 2 2 Affinity Capture-MS, Biochemical Activity
SCH9 YHR205W AGC family protein kinase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 2 2 2 Dosage Rescue, Positive Genetic
AGX1 YFL030W Alanine:glyoxylate aminotransferase (AGT) physical 2 2 2 Affinity Capture-MS, Biochemical Activity
ELM1 YKL048C Serine/threonine protein kinase genetic 2 2 2 Dosage Lethality, Dosage Growth Defect
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 2 2 2 Positive Genetic, Phenotypic Suppression
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 2 2 2 Synthetic Lethality, Dosage Lethality
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 2 2 2 Dosage Lethality, Synthetic Growth Defect
BRE1 YDL074C E3 ubiquitin ligase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
ASF1 YJL115W Nucleosome assembly factor genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
NUM1 YDR150W Protein required for nuclear migration genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes physical 2 1 2 Biochemical Activity, Biochemical Activity
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 2 1 2 Dosage Lethality, Dosage Lethality
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme physical 2 1 2 Two-hybrid, Two-hybrid
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 2 1 2 Biochemical Activity, Biochemical Activity
SHS1 YDL225W Component of the septin ring that is required for cytokinesis physical 2 1 2 Biochemical Activity, Biochemical Activity
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 2 1 2 Biochemical Activity, Biochemical Activity
SSD1 YDR293C Translational repressor physical 2 1 2 Biochemical Activity, Biochemical Activity
WHI5 YOR083W Repressor of G1 transcription physical 2 1 2 Biochemical Activity, Biochemical Activity
SHC1 YER096W Sporulation-specific activator of Chs3p (chitin synthase III) genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SFL1 YOR140W Transcriptional repressor and activator genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SMF1 YOL122C Divalent metal ion transporter genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
TAT2 YOL020W High affinity tryptophan and tyrosine permease genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
TPM1 YNL079C Major isoform of tropomyosin genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
VAN1 YML115C Component of the mannan polymerase I genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
WSC4 YHL028W Endoplasmic reticulum (ER) membrane protein genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
TPA1 YER049W Prolyl hydroxylase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
RTS3 YGR161C Putative component of the protein phosphatase type 2A complex genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
YJR142W YJR142W 8-oxo-dGTP diphosphatase of the Nudix hydrolase family genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
BIL2 YGL015C Formin inhibitor genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p physical 2 1 2 Biochemical Activity, Biochemical Activity
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ELO3 YLR372W Elongase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
PHO80 YOL001W Cyclin genetic 2 1 2 Dosage Rescue, Dosage Rescue
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex physical 2 1 2 Biochemical Activity, Biochemical Activity
INP51 YIL002C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
IGD1 YFR017C Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity physical 2 1 2 Biochemical Activity, Biochemical Activity
PAN5 YHR063C 2-dehydropantoate 2-reductase genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
FKS3 YMR306W Protein involved in spore wall assembly genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p physical 2 2 1 Reconstituted Complex, Two-hybrid
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 2 1 Phenotypic Enhancement, Synthetic Lethality
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 2 2 1 Phenotypic Suppression, Synthetic Growth Defect
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle physical 2 2 1 Reconstituted Complex, Two-hybrid
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 2 2 1 Phenotypic Suppression, Synthetic Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Dosage Lethality
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing physical 1 1 1 Biochemical Activity
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 1 1 1 Biochemical Activity
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing physical 1 1 1 Biochemical Activity
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function physical 1 1 1 Biochemical Activity
HAS1 YMR290C ATP-dependent RNA helicase physical 1 1 1 Biochemical Activity
HAS1 YMR290C ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Dosage Lethality
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic physical 1 1 1 Biochemical Activity
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Biochemical Activity
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Dosage Lethality
NPL3 YDR432W RNA-binding protein physical 1 1 1 Biochemical Activity
DIS3 YOL021C Exosome core complex catalytic subunit physical 1 1 1 Biochemical Activity
FMP52 YER004W Protein of unknown function genetic 1 1 1 Negative Genetic
MFT1 YML062C Subunit of the THO complex physical 1 1 1 Biochemical Activity
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing physical 1 1 1 Biochemical Activity
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Biochemical Activity
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p physical 1 1 1 Biochemical Activity
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 1 1 1 Biochemical Activity
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Positive Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments physical 1 1 1 Biochemical Activity
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Phenotypic Enhancement
CDC11 YJR076C Component of the septin ring that is required for cytokinesis physical 1 1 1 Biochemical Activity
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Phenotypic Enhancement
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Dosage Lethality
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex physical 1 1 1 Biochemical Activity
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) physical 1 1 1 Biochemical Activity
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
CNS1 YBR155W TPR-containing co-chaperone physical 1 1 1 Biochemical Activity
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Affinity Capture-MS
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites physical 1 1 1 Biochemical Activity
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Biochemical Activity
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Biochemical Activity
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Biochemical Activity
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase physical 1 1 1 Biochemical Activity
HRP1 YOL123W Subunit of cleavage factor I physical 1 1 1 Biochemical Activity
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex physical 1 1 1 Biochemical Activity
ACK1 YDL203C Protein that functions in the cell wall integrity pathway physical 1 1 1 Biochemical Activity
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family physical 1 1 1 Biochemical Activity
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Dosage Lethality
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Biochemical Activity
MAL12 YGR292W Maltase (alpha-D-glucosidase) physical 1 1 1 Biochemical Activity
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) physical 1 1 1 Biochemical Activity
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Biochemical Activity
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Biochemical Activity
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase physical 1 1 1 Biochemical Activity
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 1 1 1 Biochemical Activity
MRP51 YPL118W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Biochemical Activity
ATG3 YNR007C E2-like enzyme physical 1 1 1 Biochemical Activity
MLC2 YPR188C Regulatory light chain for the type II myosin Myo1p physical 1 1 1 Biochemical Activity
CMD1 YBR109C Calmodulin physical 1 1 1 Biochemical Activity
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Dosage Growth Defect
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein physical 1 1 1 Biochemical Activity
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase physical 1 1 1 Biochemical Activity
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Biochemical Activity
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Synthetic Growth Defect
ATG18 YFR021W Phosphoinositide binding protein physical 1 1 1 Biochemical Activity
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Dosage Lethality
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Two-hybrid
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Dosage Lethality
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) physical 1 1 1 Biochemical Activity
NAB6 YML117W Putative RNA-binding protein physical 1 1 1 Biochemical Activity
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway physical 1 1 1 Biochemical Activity
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Biochemical Activity
HOS4 YIL112W Subunit of the Set3 complex physical 1 1 1 Biochemical Activity
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Biochemical Activity
GAL83 YER027C One of three alternate beta-subunits of the Snf1 kinase complex physical 1 1 1 Biochemical Activity
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Biochemical Activity
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Biochemical Activity
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) physical 1 1 1 Biochemical Activity
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Synthetic Rescue
GLN1 YPR035W Glutamine synthetase (GS) physical 1 1 1 Biochemical Activity
MCM2 YBL023C Protein involved in DNA replication physical 1 1 1 Biochemical Activity
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis physical 1 1 1 Biochemical Activity
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Biochemical Activity
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) physical 1 1 1 Biochemical Activity
CMS1 YLR003C Putative subunit of the 90S preribosome processome complex physical 1 1 1 Biochemical Activity
BNA3 YJL060W Kynurenine aminotransferase physical 1 1 1 Biochemical Activity
LAP2 YNL045W Leucyl aminopeptidase yscIV with epoxide hydrolase activity physical 1 1 1 Biochemical Activity
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis physical 1 1 1 Biochemical Activity
EDC3 YEL015W Non-essential conserved protein with a role in mRNA decapping physical 1 1 1 Biochemical Activity
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen physical 1 1 1 Biochemical Activity
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Synthetic Growth Defect
CAR2 YLR438W L-ornithine transaminase (OTAse) physical 1 1 1 Biochemical Activity
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Biochemical Activity
FAR8 YMR029C Protein involved in recovery from arrest in response to pheromone physical 1 1 1 Biochemical Activity
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Phenotypic Suppression
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) physical 1 1 1 Biochemical Activity
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Positive Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response physical 1 1 1 Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 1 1 1 Affinity Capture-MS
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Phenotypic Suppression
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase physical 1 1 1 Affinity Capture-MS
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Phenotypic Enhancement
SOR1 YJR159W Sorbitol dehydrogenase physical 1 1 1 Two-hybrid
SOR2 YDL246C Sorbitol dehydrogenase physical 1 1 1 Two-hybrid
PSY2 YNL201C Subunit of protein phosphatase PP4 complex physical 1 1 1 Two-hybrid
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 1 1 1 Biochemical Activity
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Synthetic Lethality
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) physical 1 1 1 Biochemical Activity
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p physical 1 1 1 Biochemical Activity
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 1 1 1 Biochemical Activity
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Biochemical Activity
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Biochemical Activity
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase physical 1 1 1 Biochemical Activity
SAP185 YJL098W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Dosage Lethality
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 1 1 1 Biochemical Activity
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase physical 1 1 1 Biochemical Activity
PIB2 YGL023C Phosphatidylinositol 3-phosphate binding protein physical 1 1 1 Biochemical Activity
YIF1 YNL263C Integral membrane protein physical 1 1 1 Biochemical Activity
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
RDR1 YOR380W Transcriptional repressor involved in regulating multidrug resistance physical 1 1 1 Two-hybrid
POG1 YIL122W DNA-binding transcriptional activator physical 1 1 1 Two-hybrid
URK1 YNR012W Uridine/cytidine kinase physical 1 1 1 Two-hybrid
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor physical 1 1 1 Biochemical Activity
RBH1 YJL181W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 1 1 1 Affinity Capture-MS
RCK1 YGL158W Protein kinase involved in oxidative stress response genetic 1 1 1 Dosage Lethality
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Biochemical Activity
TDA3 YHR009C Putative oxidoreductase involved in late endosome to Golgi transport physical 1 1 1 Biochemical Activity
RGD3 YHR182W GTPase activating protein (GAP) for Rho3p, involved in cell polarity g physical 1 1 1 Biochemical Activity
YDR170W-A YDR170W-A Retrotransposon TYA Gag gene physical 1 1 1 Biochemical Activity
PXL1 YKR090W Protein that localizes to sites of polarized growth physical 1 1 1 Biochemical Activity
YGR038C-A YGR038C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RAI1 YGL246C Nuclear decapping endonuclease physical 1 1 1 Biochemical Activity
PRE2 YPR103W Beta 5 subunit of the 20S proteasome physical 1 1 1 Biochemical Activity
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth physical 1 1 1 Biochemical Activity
YGR111W YGR111W Putative protein of unknown function physical 1 1 1 Biochemical Activity
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor physical 1 1 1 Biochemical Activity
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Biochemical Activity
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Biochemical Activity
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 1 1 1 Biochemical Activity
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 Biochemical Activity
TGL3 YMR313C Bifunctional triacylglycerol lipase and LPE acyltransferase physical 1 1 1 Biochemical Activity
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Biochemical Activity
YPR158W-A YPR158W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YNL165W YNL165W Putative protein of unknown function physical 1 1 1 Biochemical Activity
RGM1 YMR182C Putative zinc finger DNA binding transcription factor physical 1 1 1 Biochemical Activity
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor physical 1 1 1 Biochemical Activity
YLR410W-A YLR410W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Biochemical Activity
UTP7 YER082C Nucleolar protein physical 1 1 1 Biochemical Activity
UBP6 YFR010W Ubiquitin-specific protease physical 1 1 1 Biochemical Activity
YPT11 YNL304W Rab GTPase physical 1 1 1 Biochemical Activity
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 Biochemical Activity
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p genetic 1 1 1 Dosage Lethality
YAT2 YER024W Carnitine acetyltransferase physical 1 1 1 Biochemical Activity
SET4 YJL105W Chromatin-associated protein involved in control of stress response physical 1 1 1 Biochemical Activity
YMR262W YMR262W Protein of unknown function physical 1 1 1 Biochemical Activity
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein physical 1 1 1 Biochemical Activity
YGR026W YGR026W Putative protein of unknown function physical 1 1 1 Biochemical Activity
SYG1 YIL047C Plasma membrane protein of unknown function physical 1 1 1 Biochemical Activity
RIM4 YHL024W Putative RNA-binding protein physical 1 1 1 Biochemical Activity
YDR034C-C YDR034C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YGR027W-A YGR027W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RAX1 YOR301W Protein involved in establishing bud site selection physical 1 1 1 Biochemical Activity
YOL103W-A YOL103W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase physical 1 1 1 Biochemical Activity
YMR046C YMR046C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
TOS4 YLR183C Putative transcription factor, contains Forkhead Associated domain physical 1 1 1 Biochemical Activity
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
YLR125W YLR125W Putative protein of unknown function physical 1 1 1 Biochemical Activity
YBL086C YBL086C Protein of unknown function physical 1 1 1 Biochemical Activity
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Biochemical Activity
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Biochemical Activity
YMR155W YMR155W Putative protein of unknown function physical 1 1 1 Biochemical Activity
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B physical 1 1 1 Biochemical Activity
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 1 1 1 Positive Genetic
TRM1 YDR120C tRNA methyltransferase physical 1 1 1 Biochemical Activity
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 1 1 1 Biochemical Activity
YGL185C YGL185C Putative protein with sequence similar to hydroxyacid dehydrogenases physical 1 1 1 Biochemical Activity
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Biochemical Activity
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
SGN1 YIR001C Cytoplasmic RNA-binding protein physical 1 1 1 Biochemical Activity
SVF1 YDR346C Protein with a potential role in cell survival pathways physical 1 1 1 Biochemical Activity
YML045W-A YML045W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YNL054W-A YNL054W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YPL257W-A YPL257W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit physical 1 1 1 Biochemical Activity
PHO91 YNR013C Low-affinity vacuolar phosphate transporter physical 1 1 1 Biochemical Activity
PHO91 YNR013C Low-affinity vacuolar phosphate transporter genetic 1 1 1 Phenotypic Enhancement
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component physical 1 1 1 Biochemical Activity
SHC1 YER096W Sporulation-specific activator of Chs3p (chitin synthase III) physical 1 1 1 Biochemical Activity
THP1 YOL072W Nuclear pore-associated protein physical 1 1 1 Biochemical Activity
SER1 YOR184W 3-phosphoserine aminotransferase physical 1 1 1 Biochemical Activity
PML1 YLR016C Subunit of the RES complex physical 1 1 1 Biochemical Activity
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase physical 1 1 1 Biochemical Activity
RSA1 YPL193W Protein involved in the assembly of 60S ribosomal subunits physical 1 1 1 Biochemical Activity
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase physical 1 1 1 Biochemical Activity
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 1 1 1 Biochemical Activity
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis physical 1 1 1 Biochemical Activity
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis genetic 1 1 1 Dosage Lethality
RPS26B YER131W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Biochemical Activity
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex physical 1 1 1 Biochemical Activity
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking physical 1 1 1 Biochemical Activity
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Biochemical Activity
RGI1 YER067W Protein involved in energy metabolism under respiratory conditions physical 1 1 1 Biochemical Activity
YKR018C YKR018C Protein of unknown function physical 1 1 1 Biochemical Activity
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex physical 1 1 1 Biochemical Activity
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Biochemical Activity
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Biochemical Activity
YML119W YML119W Putative protein of unknown function physical 1 1 1 Biochemical Activity
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 1 1 1 Biochemical Activity
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p physical 1 1 1 Biochemical Activity
SPE4 YLR146C Spermine synthase physical 1 1 1 Biochemical Activity
YIG1 YPL201C Protein that interacts with glycerol 3-phosphatase physical 1 1 1 Biochemical Activity
YNR064C YNR064C Epoxide hydrolase physical 1 1 1 Biochemical Activity
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 1 1 1 Biochemical Activity
SCH9 YHR205W AGC family protein kinase physical 1 1 1 Biochemical Activity
RKM4 YDR257C Ribosomal lysine methyltransferase physical 1 1 1 Biochemical Activity
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA physical 1 1 1 Biochemical Activity
SUB1 YMR039C Transcriptional regulator physical 1 1 1 Biochemical Activity
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation physical 1 1 1 Biochemical Activity
YGL039W YGL039W Aldehyde reductase physical 1 1 1 Biochemical Activity
YPR147C YPR147C Bifunctional triacylglycerol lipase and short chain ester hydrolase physical 1 1 1 Biochemical Activity
PRC1 YMR297W Vacuolar carboxypeptidase Y (proteinase C, CPY) physical 1 1 1 Biochemical Activity
YPR089W YPR089W Protein of unknown function physical 1 1 1 Biochemical Activity
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance physical 1 1 1 Biochemical Activity
YPT7 YML001W Rab family GTPase physical 1 1 1 Biochemical Activity
YJR154W YJR154W Putative protein of unknown function physical 1 1 1 Biochemical Activity
YBR287W YBR287W Protein of unknown function physical 1 1 1 Biochemical Activity
PYC1 YGL062W Pyruvate carboxylase isoform physical 1 1 1 Biochemical Activity
SDS23 YGL056C Protein involved in cell separation during budding physical 1 1 1 Biochemical Activity
YJL218W YJL218W Mitochondrial protein, putative acetyltransferase physical 1 1 1 Biochemical Activity
TRP4 YDR354W Anthranilate phosphoribosyl transferase physical 1 1 1 Biochemical Activity
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Biochemical Activity
TCA17 YEL048C Component of transport protein particle (TRAPP) complex II physical 1 1 1 Biochemical Activity
RPL29 YFR032C-A Ribosomal 60S subunit protein L29 physical 1 1 1 Biochemical Activity
ROG3 YFR022W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 1 1 1 Biochemical Activity
URA7 YBL039C Major CTP synthase isozyme (see also URA8) physical 1 1 1 Biochemical Activity
YHR112C YHR112C Protein of unknown function physical 1 1 1 Biochemical Activity
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Biochemical Activity
YKR041W YKR041W Protein of unknown function physical 1 1 1 Biochemical Activity
SER33 YIL074C 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 1 1 1 Biochemical Activity
YDL186W YDL186W Putative protein of unknown function physical 1 1 1 Biochemical Activity
YAP3 YHL009C Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Biochemical Activity
PTC1 YDL006W Type 2C protein phosphatase (PP2C) physical 1 1 1 Biochemical Activity
YIP5 YGL161C Protein that interacts with Rab GTPases physical 1 1 1 Biochemical Activity
REC104 YHR157W Protein involved in early stages of meiotic recombination physical 1 1 1 Biochemical Activity
YPT6 YLR262C Rab family GTPase physical 1 1 1 Biochemical Activity
RAM2 YKL019W Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I physical 1 1 1 Biochemical Activity
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p physical 1 1 1 Biochemical Activity
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 1 1 1 Biochemical Activity
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) physical 1 1 1 Biochemical Activity
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity physical 1 1 1 Biochemical Activity
ZRG8 YER033C Protein of unknown function physical 1 1 1 Biochemical Activity
RCI37 YIL077C Protein that associates with the large mitoribosomal subunit physical 1 1 1 Biochemical Activity
RNH202 YDR279W Ribonuclease H2 subunit physical 1 1 1 Biochemical Activity
RNH202 YDR279W Ribonuclease H2 subunit genetic 1 1 1 Dosage Lethality
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase physical 1 1 1 Biochemical Activity
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 1 1 1 Biochemical Activity
YFR035C YFR035C Putative protein of unknown function physical 1 1 1 Biochemical Activity
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p physical 1 1 1 Biochemical Activity
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Biochemical Activity
YER034W YER034W Protein of unknown function physical 1 1 1 Biochemical Activity
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Biochemical Activity
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Biochemical Activity
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex physical 1 1 1 Biochemical Activity
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome physical 1 1 1 Biochemical Activity
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes physical 1 1 1 Biochemical Activity
RAD51 YER095W Strand exchange protein physical 1 1 1 Biochemical Activity
TRM8 YDL201W Catalytic subunit of a tRNA methyltransferase complex physical 1 1 1 Biochemical Activity
PTC2 YER089C Type 2C protein phosphatase (PP2C) physical 1 1 1 Biochemical Activity
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Dosage Lethality
STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein physical 1 1 1 Biochemical Activity
STB3 YDR169C Ribosomal RNA processing element (RRPE)-binding protein genetic 1 1 1 Dosage Lethality
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 1 1 1 Biochemical Activity
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p genetic 1 1 1 Dosage Lethality
REX2 YLR059C 3'-5' RNA exonuclease physical 1 1 1 Biochemical Activity
VPS29 YHR012W Subunit of the membrane-associated retromer complex physical 1 1 1 Biochemical Activity
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Biochemical Activity
TMA19 YKL056C Protein that associates with ribosomes physical 1 1 1 Biochemical Activity
SLZ1 YNL196C Sporulation-specific protein with a leucine zipper motif physical 1 1 1 Biochemical Activity
YLR030W YLR030W Putative protein of unknown function physical 1 1 1 Biochemical Activity
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein physical 1 1 1 Biochemical Activity
TUM1 YOR251C Rhodanese domain sulfur transferase physical 1 1 1 Biochemical Activity
SML1 YML058W Ribonucleotide reductase inhibitor physical 1 1 1 Biochemical Activity
YLR460C YLR460C Member of the quinone oxidoreductase family physical 1 1 1 Biochemical Activity
SPO13 YHR014W Meiotic regulator physical 1 1 1 Biochemical Activity
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Biochemical Activity
THI4 YGR144W Thiazole synthase physical 1 1 1 Biochemical Activity
YMR31 YFR049W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase physical 1 1 1 Biochemical Activity
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 1 1 1 Biochemical Activity
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
URA8 YJR103W Minor CTP synthase isozyme (see also URA7) physical 1 1 1 Biochemical Activity
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 Biochemical Activity
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Dosage Lethality
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 1 1 1 Biochemical Activity
RGI2 YIL057C Protein of unknown function physical 1 1 1 Biochemical Activity
RGI2 YIL057C Protein of unknown function genetic 1 1 1 Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting physical 1 1 1 Biochemical Activity
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex physical 1 1 1 Biochemical Activity
VAC7 YNL054W Integral vacuolar membrane protein physical 1 1 1 Biochemical Activity
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 1 1 1 Biochemical Activity
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Synthetic Lethality
SPO12 YHR152W Nucleolar protein of unknown function genetic 1 1 1 Phenotypic Enhancement
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Synthetic Growth Defect
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Synthetic Growth Defect
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Synthetic Growth Defect
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Growth Defect
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Synthetic Growth Defect
PHO87 YCR037C Low-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Phenotypic Enhancement
PHO90 YJL198W Low-affinity phosphate transporter genetic 1 1 1 Phenotypic Enhancement
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Synthetic Growth Defect
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Synthetic Growth Defect
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Synthetic Growth Defect
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Synthetic Growth Defect
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
PMP2 YEL017C-A Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) genetic 1 1 1 Dosage Lethality
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Dosage Lethality
PMT3 YOR321W Protein O-mannosyltransferase genetic 1 1 1 Dosage Lethality
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Dosage Lethality
PPH22 YDL188C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Dosage Lethality
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Dosage Lethality
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress genetic 1 1 1 Dosage Lethality
RDI1 YDL135C Rho GDP dissociation inhibitor genetic 1 1 1 Dosage Lethality
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Dosage Lethality
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p genetic 1 1 1 Dosage Lethality
RPI1 YIL119C Transcription factor, allelic differences between S288C and Sigma1278b genetic 1 1 1 Dosage Lethality
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Dosage Lethality
SKS1 YPL026C Putative serine/threonine protein kinase genetic 1 1 1 Dosage Lethality
SNL1 YIL016W Ribosome-associated protein genetic 1 1 1 Dosage Lethality
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Lethality
TIF3 YPR163C Translation initiation factor eIF-4B genetic 1 1 1 Dosage Lethality
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase genetic 1 1 1 Dosage Lethality
VPS68 YOL129W Vacuolar membrane protein of unknown function genetic 1 1 1 Dosage Lethality
VTC2 YFL004W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Dosage Lethality
YPQ1 YOL092W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Dosage Lethality
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Dosage Lethality
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Phenotypic Suppression
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Phenotypic Suppression
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
STB5 YHR178W Transcription factor genetic 1 1 1 Positive Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Positive Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
RRS1 YOR294W Essential protein that binds ribosomal protein L11 genetic 1 1 1 Negative Genetic
SIP4 YJL089W C6 zinc cluster transcriptional activator genetic 1 1 1 Dosage Lethality
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Dosage Lethality
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif genetic 1 1 1 Dosage Lethality
USV1 YPL230W Putative transcription factor containing a C2H2 zinc finger genetic 1 1 1 Dosage Lethality
TDA9 YML081W Transcription factor that regulates acetate production genetic 1 1 1 Dosage Lethality
TOS8 YGL096W Homeodomain-containing protein and putative transcription factor genetic 1 1 1 Dosage Lethality
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Negative Genetic
PSR2 YLR019W Putative plasma membrane phosphatase genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Positive Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase physical 1 1 1 Biochemical Activity
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein physical 1 1 1 Biochemical Activity
MPC54 YOR177C Component of the meiotic outer plaque physical 1 1 1 Biochemical Activity
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism physical 1 1 1 Biochemical Activity
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Synthetic Lethality
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Positive Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism physical 1 1 1 Affinity Capture-MS
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor genetic 1 1 1 Phenotypic Suppression
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Synthetic Lethality
KDX1 YKL161C Protein kinase physical 1 1 1 PCA
LIA1 YJR070C Deoxyhypusine hydroxylase physical 1 1 1 Biochemical Activity
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Synthetic Growth Defect
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 1 1 1 Dosage Lethality
PDS1 YDR113C Securin physical 1 1 1 Biochemical Activity
ARE2 YNR019W Acyl-CoA:sterol acyltransferase physical 1 1 1 Biochemical Activity
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein physical 1 1 1 Biochemical Activity
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone physical 1 1 1 Biochemical Activity
HSL7 YBR133C Protein arginine N-methyltransferase physical 1 1 1 Biochemical Activity
PDC5 YLR134W Minor isoform of pyruvate decarboxylase physical 1 1 1 Biochemical Activity
ERG20 YJL167W Farnesyl pyrophosphate synthetase physical 1 1 1 Biochemical Activity
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members physical 1 1 1 Biochemical Activity
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members genetic 1 1 1 Dosage Lethality
DSS4 YPR017C Guanine nucleotide dissociation stimulator for Sec4p physical 1 1 1 Biochemical Activity
NTF2 YER009W Nuclear envelope protein physical 1 1 1 Biochemical Activity
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Dosage Lethality
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Biochemical Activity
NPA3 YJR072C Member of the conserved GPN-loop GTPase family physical 1 1 1 Biochemical Activity
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Dosage Lethality
MAG2 YLR427W Cytoplasmic protein of unknown function physical 1 1 1 Biochemical Activity
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Positive Genetic
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
CTF4 YPR135W Chromatin-associated protein physical 1 1 1 Biochemical Activity
IRA1 YBR140C GTPase-activating protein genetic 1 1 1 Positive Genetic
MNN9 YPL050C Subunit of Golgi mannosyltransferase complex physical 1 1 1 Biochemical Activity
PGM1 YKL127W Phosphoglucomutase, minor isoform physical 1 1 1 Biochemical Activity
LUG1 YLR352W Protein of unknown function with similarity to F-box proteins genetic 1 1 1 Dosage Lethality
FPK1 YNR047W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
ARF2 YDL137W ADP-ribosylation factor physical 1 1 1 Biochemical Activity
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-MS
NOP53 YPL146C Nucleolar protein physical 1 1 1 Biochemical Activity
GSY1 YFR015C Glycogen synthase physical 1 1 1 Affinity Capture-MS
GSY1 YFR015C Glycogen synthase genetic 1 1 1 Dosage Lethality
HMG2 YLR450W HMG-CoA reductase physical 1 1 1 Biochemical Activity
APA1 YCL050C AP4A phosphorylase physical 1 1 1 Biochemical Activity
LIF1 YGL090W Component of the DNA ligase IV complex genetic 1 1 1 Positive Genetic
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 1 1 1 Biochemical Activity
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Dosage Lethality
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Synthetic Lethality
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Biochemical Activity
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Dosage Lethality
MRX1 YER077C Protein that associates with mitochondrial ribosome physical 1 1 1 Biochemical Activity
BNA5 YLR231C Kynureninase physical 1 1 1 Biochemical Activity
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p physical 1 1 1 Biochemical Activity
ARO9 YHR137W Aromatic aminotransferase II physical 1 1 1 Biochemical Activity
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 1 1 1 Dosage Lethality
FZF1 YGL254W Transcription factor involved in sulfite metabolism physical 1 1 1 Biochemical Activity
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Dosage Lethality
GLG2 YJL137C Glycogenin glucosyltransferase physical 1 1 1 Biochemical Activity
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
CLN3 YAL040C G1 cyclin involved in cell cycle progression physical 1 1 1 Biochemical Activity
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 1 1 1 Synthetic Lethality
DAL82 YNL314W Positive regulator of allophanate inducible genes physical 1 1 1 Biochemical Activity
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Dosage Lethality
CUP2 YGL166W Copper-binding transcription factor genetic 1 1 1 Dosage Lethality
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Dosage Lethality
ACO2 YJL200C Putative mitochondrial aconitase isozyme physical 1 1 1 Biochemical Activity
ATG19 YOL082W Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway physical 1 1 1 Biochemical Activity
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) physical 1 1 1 Biochemical Activity
LPP1 YDR503C Lipid phosphate phosphatase genetic 1 1 1 Negative Genetic
CSM3 YMR048W Replication fork associated factor physical 1 1 1 Biochemical Activity
PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies physical 1 1 1 Biochemical Activity
MRX16 YDR132C Protein that associates with the large mitoribosomal subunit physical 1 1 1 Biochemical Activity
NBA1 YOL070C Protein involved in axial bud site selection physical 1 1 1 Biochemical Activity
NTC20 YBR188C Member of the NineTeen Complex (NTC) physical 1 1 1 Biochemical Activity
PEX14 YGL153W Central component of the peroxisomal importomer complex physical 1 1 1 Biochemical Activity
MVP1 YMR004W Protein required for sorting proteins to the vacuole physical 1 1 1 Biochemical Activity
IMA3 YIL172C Alpha-glucosidase physical 1 1 1 Biochemical Activity
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Positive Genetic
FMP40 YPL222W Mitochondrial AMPylator in the pseudokinase selenoprotein-O family physical 1 1 1 Biochemical Activity
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Biochemical Activity
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Biochemical Activity
CDC26 YFR036W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) physical 1 1 1 Biochemical Activity
COG7 YGL005C Component of the conserved oligomeric Golgi complex physical 1 1 1 Biochemical Activity
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase physical 1 1 1 Biochemical Activity
AMD1 YML035C AMP deaminase physical 1 1 1 Biochemical Activity
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) genetic 1 1 1 Synthetic Rescue
MIF2 YKL089W Centromeric CDEIII region binding protein genetic 1 1 1 Negative Genetic
ATG8 YBL078C Ub-like protein physical 1 1 1 Biochemical Activity
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
BUD4 YJR092W Anillin-like protein involved in bud-site selection physical 1 1 1 Biochemical Activity
CLC1 YGR167W Clathrin light chain physical 1 1 1 Biochemical Activity
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Lethality
BNI5 YNL166C Linker protein responsible for recruitment of myosin to the bud neck physical 1 1 1 Biochemical Activity
IOC2 YLR095C Subunit of the Isw1b complex genetic 1 1 1 Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Synthetic Lethality
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex physical 1 1 1 Biochemical Activity
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting physical 1 1 1 Biochemical Activity
CNM67 YNL225C Component of the spindle pole body outer plaque physical 1 1 1 Biochemical Activity
JNM1 YMR294W Component of the yeast dynactin complex physical 1 1 1 Biochemical Activity
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Synthetic Growth Defect
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Dosage Lethality
MBF1 YOR298C-A Transcriptional coactivator physical 1 1 1 Biochemical Activity
GAL10 YBR019C UDP-glucose-4-epimerase physical 1 1 1 Biochemical Activity
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Dosage Lethality
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Synthetic Growth Defect
CAF16 YFL028C Part of evolutionarily-conserved CCR4-NOT regulatory complex physical 1 1 1 Biochemical Activity
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator genetic 1 1 1 Dosage Lethality
GSY2 YLR258W Glycogen synthase genetic 1 1 1 Dosage Lethality
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation physical 1 1 1 Biochemical Activity
GAD1 YMR250W Glutamate decarboxylase physical 1 1 1 Biochemical Activity
ALY1 YKR021W Alpha arrestin, substrate of calcineurin physical 1 1 1 Biochemical Activity
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Biochemical Activity
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Dosage Lethality
PEX11 YOL147C Peroxisomal protein required for medium-chain fatty acid oxidation physical 1 1 1 Biochemical Activity
GYL1 YMR192W Putative GTPase activating protein (GAP) with a role in exocytosis physical 1 1 1 Biochemical Activity
IVY1 YDR229W Phospholipid-binding protein that interacts with both Ypt7p and Vps33p physical 1 1 1 Biochemical Activity
BAT2 YJR148W Cytosolic branched-chain amino acid (BCAA) aminotransferase physical 1 1 1 Biochemical Activity
MGA1 YGR249W Protein similar to heat shock transcription factor physical 1 1 1 Biochemical Activity
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
HRD1 YOL013C Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) genetic 1 1 1 Dosage Lethality
HOC1 YJR075W Alpha-1,6-mannosyltransferase physical 1 1 1 Biochemical Activity
CAP2 YIL034C Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) physical 1 1 1 Biochemical Activity
GSM1 YJL103C Putative zinc cluster protein of unknown function physical 1 1 1 Biochemical Activity
PAN3 YKL025C Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex physical 1 1 1 Biochemical Activity
DYS1 YHR068W Deoxyhypusine synthase physical 1 1 1 Biochemical Activity
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response physical 1 1 1 PCA
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex physical 1 1 1 Biochemical Activity
COX19 YLL018C-A Protein required for cytochrome c oxidase assembly physical 1 1 1 Biochemical Activity
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 1 1 1 Biochemical Activity
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase physical 1 1 1 Biochemical Activity
ABZ1 YNR033W Para-aminobenzoate (PABA) synthase physical 1 1 1 Biochemical Activity
PAR32 YDL173W Low complexity protein physical 1 1 1 Biochemical Activity
FOX2 YKR009C 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase physical 1 1 1 Biochemical Activity
LYS21 YDL131W Homocitrate synthase isozyme physical 1 1 1 Biochemical Activity
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis physical 1 1 1 Biochemical Activity
MRC1 YCL061C S-phase checkpoint protein required for DNA replication physical 1 1 1 Biochemical Activity
INH1 YDL181W Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase physical 1 1 1 Biochemical Activity
FUR1 YHR128W Uracil phosphoribosyltransferase physical 1 1 1 Biochemical Activity
CST26 YBR042C Acyltransferase physical 1 1 1 Biochemical Activity
MIG2 YGL209W Zinc finger transcriptional repressor physical 1 1 1 Biochemical Activity
AVT6 YER119C Vacuolar aspartate and glutamate exporter physical 1 1 1 Biochemical Activity
BSC6 YOL137W Protein of unknown function with 8 putative transmembrane segments genetic 1 1 1 Dosage Lethality
GDA1 YEL042W Guanosine diphosphatase located in the Golgi physical 1 1 1 Biochemical Activity
PEX1 YKL197C AAA-peroxin physical 1 1 1 Biochemical Activity
EXP1 YDL121C A cargo receptor protein for Pma1p genetic 1 1 1 Dosage Lethality
BDH1 YAL060W NAD-dependent (R,R)-butanediol dehydrogenase physical 1 1 1 Biochemical Activity
HYR1 YIR037W Glutathione peroxidase physical 1 1 1 Biochemical Activity
AVT1 YJR001W Vacuolar transporter physical 1 1 1 Biochemical Activity
PAM1 YDR251W Essential protein of unknown function physical 1 1 1 Biochemical Activity
KXD1 YGL079W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Biochemical Activity
DDR48 YMR173W DNA damage-responsive protein physical 1 1 1 Biochemical Activity
MET12 YPL023C Protein with MTHFR activity in vitro physical 1 1 1 Biochemical Activity
NDT80 YHR124W Meiosis-specific transcription factor genetic 1 1 1 Dosage Lethality
HIS6 YIL020C Enzyme that catalyzes the fourth step in the histidine pathway physical 1 1 1 Biochemical Activity
AQY3 YFL054C Putative channel-like protein physical 1 1 1 Biochemical Activity
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Synthetic Growth Defect
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family physical 1 1 1 Biochemical Activity
FRD1 YEL047C Soluble fumarate reductase physical 1 1 1 Biochemical Activity
GTT3 YEL017W Protein of unknown function may be involved in glutathione metabolism physical 1 1 1 Biochemical Activity
APD1 YBR151W 2Fe-2S cytosolic protein of unknown function physical 1 1 1 Biochemical Activity
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b physical 1 1 1 Biochemical Activity
MIL1 YFL034W Predicted lipase physical 1 1 1 Biochemical Activity
ISR1 YPR106W Predicted protein kinase physical 1 1 1 Biochemical Activity
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase physical 1 1 1 Biochemical Activity
ABP140 YOR239W AdoMet-dependent tRNA methyltransferase and actin binding protein genetic 1 1 1 Dosage Lethality
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Biochemical Activity
ATG21 YPL100W Phosphoinositide binding protein physical 1 1 1 Biochemical Activity
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
DEG1 YFL001W tRNA:pseudouridine synthase physical 1 1 1 Biochemical Activity
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) physical 1 1 1 Biochemical Activity
INP54 YOL065C Phosphatidylinositol 4,5-bisphosphate 5-phosphatase genetic 1 1 1 Dosage Lethality
NVJ2 YPR091C Lipid-binding ER protein, enriched at nucleus-vacuolar junctions (NVJ) physical 1 1 1 Biochemical Activity
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis physical 1 1 1 Biochemical Activity
AIM39 YOL053W Protein of unknown function physical 1 1 1 Biochemical Activity
COQ8 YGL119W ATPase required for ubiquinone biosynthesis and respiratory growth physical 1 1 1 Biochemical Activity
MET2 YNL277W L-homoserine-O-acetyltransferase physical 1 1 1 Biochemical Activity
LOA1 YPR139C Lysophosphatidic acid acyltransferase physical 1 1 1 Biochemical Activity
DAP2 YHR028C Dipeptidyl aminopeptidase physical 1 1 1 Biochemical Activity
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p physical 1 1 1 Biochemical Activity
DIA1 YMR316W Protein of unknown function physical 1 1 1 Biochemical Activity
MTG2 YHR168W Putative GTPase physical 1 1 1 Biochemical Activity
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Synthetic Growth Defect
DOT5 YIL010W Nuclear thiol peroxidase physical 1 1 1 Biochemical Activity
ERR2 YPL281C Enolase, a phosphopyruvate hydratase physical 1 1 1 Biochemical Activity
ALO1 YML086C D-Arabinono-1,4-lactone oxidase physical 1 1 1 Biochemical Activity
PFA3 YNL326C Palmitoyltransferase for Vac8p physical 1 1 1 Biochemical Activity
CTA1 YDR256C Catalase A physical 1 1 1 Biochemical Activity
JJJ3 YJR097W Iron-binding protein physical 1 1 1 Biochemical Activity
EAR1 YMR171C Specificity factor required for Rsp5p-dependent ubiquitination physical 1 1 1 Biochemical Activity
AST2 YER101C Lipid raft associated protein physical 1 1 1 Biochemical Activity
CEM1 YER061C Mitochondrial beta-keto-acyl synthase physical 1 1 1 Biochemical Activity
MSP1 YGR028W Highly-conserved N-terminally anchored AAA-ATPase physical 1 1 1 Biochemical Activity
HUG1 YML058W-A Ribonucleotide reductase inhibitor physical 1 1 1 Biochemical Activity
GRX2 YDR513W Cytoplasmic glutaredoxin physical 1 1 1 Biochemical Activity
FEX2 YPL279C Protein involved in fluoride export physical 1 1 1 Biochemical Activity
EMA19 YLR050C Integral ER membrane protein involved in protein sorting physical 1 1 1 Biochemical Activity
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase physical 1 1 1 Biochemical Activity
GLO1 YML004C Monomeric glyoxalase I physical 1 1 1 Biochemical Activity
ATH1 YPR026W Acid trehalase required for utilization of extracellular trehalose physical 1 1 1 Biochemical Activity
EFM5 YGR001C S-adenosylmethionine-dependent lysine methyltransferase physical 1 1 1 Biochemical Activity
JAC1 YGL018C Specialized J-protein that functions in Fe-S cluster biogenesis physical 1 1 1 Biochemical Activity
MAM3 YOL060C Protein involved in magnesium homeostasis physical 1 1 1 Biochemical Activity
ARN1 YHL040C ARN family transporter for siderophore-iron chelates physical 1 1 1 Biochemical Activity
GSH2 YOL049W Glutathione synthetase physical 1 1 1 Biochemical Activity
MAL32 YBR299W Maltase (alpha-D-glucosidase) physical 1 1 1 Biochemical Activity
LEU2 YCL018W Beta-isopropylmalate dehydrogenase (IMDH) physical 1 1 1 Biochemical Activity
EFM3 YJR129C S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Biochemical Activity
NAT2 YGR147C Protein of unknown function genetic 1 1 1 Dosage Lethality
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
LRE1 YCL051W Protein involved in control of cell wall structure and stress response genetic 1 1 1 Dosage Lethality
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Negative Genetic
PHM8 YER037W Lysophosphatidic acid (LPA) phosphatase, nucleotidase genetic 1 1 1 Dosage Lethality