Standard name Systematic name Name description Description
ELP2 YGR200C Subunit of Elongator complex Subunit of Elongator complex; binds to microtubules via conserved alkaline residues; has two seven-bladed WD40 β propellers; Elongator complex is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin
Visualize the interactome of ELP2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.988 0.966 0.971
Cell Periphery NaN NaN 0.051

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 6090

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ELP2 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
IKI3 YLR384C Subunit of Elongator complex physical 26 5 20 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Far Western, Affinity Capture-Western, Co-purification, Reconstituted Complex, Affinity Capture-Western, Co-purification, Affinity Capture-Western
ELP3 YPL086C Subunit of Elongator complex physical 20 4 16 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex physical 18 4 12 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex physical 9 3 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, PCA, PCA
GET1 YGL020C Subunit of the GET complex genetic 7 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 7 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 7 1 5 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides physical 6 2 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 6 3 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 6 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 6 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 6 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 6 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex physical 5 3 5 Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-Western, Co-purification
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 5 3 5 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 5 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 5 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 5 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 5 3 4 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 5 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 5 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 4 3 4 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 physical 4 3 4 Affinity Capture-Western, PCA, Affinity Capture-Western, Affinity Capture-MS
BNI1 YNL271C Formin genetic 4 2 4 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 4 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 4 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 4 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ADA2 YDR448W Transcription coactivator genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HTA1 YDR225W Histone H2A genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 3 3 3 Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 3 2 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 3 3 2 Synthetic Growth Defect, Synthetic Lethality, Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Co-purification
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 3 2 2 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
PFY1 YOR122C Profilin genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 3 2 2 Negative Genetic, Negative Genetic, Positive Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
MSA2 YKR077W Putative transcriptional activator genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RMD1 YDL001W Cytoplasmic protein required for sporulation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CDC42 YLR229C Small rho-like GTPase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 2 2 2 Phenotypic Suppression, Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
HHT1 YBR010W Histone H3 genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MED2 YDL005C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 2 1 2 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 2 Negative Genetic, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 2 1 2 Negative Genetic, Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 1 2 Positive Genetic, Positive Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 2 1 2 Negative Genetic, Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 2 1 2 Negative Genetic, Negative Genetic
MUD1 YBR119W U1 snRNP A protein genetic 2 1 2 Negative Genetic, Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 2 1 2 Positive Genetic, Positive Genetic
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 2 1 2 Negative Genetic, Negative Genetic
TEF1 YPR080W Translational elongation factor EF-1 alpha genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 2 1 2 Negative Genetic, Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 2 1 2 Negative Genetic, Negative Genetic
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 2 1 2 Negative Genetic, Negative Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 2 1 2 Negative Genetic, Negative Genetic
MAL33 YBR297W MAL-activator protein genetic 2 1 2 Negative Genetic, Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 2 1 2 Negative Genetic, Negative Genetic
TCD1 YHR003C tRNA threonylcarbamoyladenosine dehydratase genetic 2 1 2 Negative Genetic, Negative Genetic
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events genetic 2 1 2 Negative Genetic, Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 2 1 2 Negative Genetic, Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 2 1 2 Negative Genetic, Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
MFA2 YNL145W Mating pheromone a-factor genetic 2 1 2 Negative Genetic, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 2 1 2 Negative Genetic, Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 2 1 2 Negative Genetic, Negative Genetic
FPK1 YNR047W Ser/Thr protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 1 2 Negative Genetic, Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 2 1 2 Negative Genetic, Negative Genetic
BBC1 YJL020C Protein possibly involved in assembly of actin patches genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 2 1 2 Negative Genetic, Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 2 2 1 Affinity Capture-Western, Co-purification
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 2 2 1 Affinity Capture-Western, Co-purification
RPB4 YJL140W RNA polymerase II subunit B32 physical 2 2 1 Affinity Capture-Western, Co-purification
RPB5 YBR154C RNA polymerase subunit ABC27 physical 2 2 1 Affinity Capture-Western, Co-purification
TUB1 YML085C Alpha-tubulin physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
TUB2 YFL037W Beta-tubulin physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 2 2 1 Positive Genetic, Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Negative Genetic, Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 2 1 1 Negative Genetic, Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 1 1 Positive Genetic, Positive Genetic
THR4 YCR053W Threonine synthase genetic 2 1 1 Negative Genetic, Negative Genetic
TRM1 YDR120C tRNA methyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 2 1 1 Negative Genetic, Negative Genetic
PSP1 YDR505C Asn and gln rich protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 2 1 1 Negative Genetic, Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 2 1 1 Negative Genetic, Negative Genetic
MET16 YPR167C 3'-phosphoadenylsulfate reductase genetic 2 1 1 Negative Genetic, Negative Genetic
PIK1 YNL267W Phosphatidylinositol 4-kinase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SOV1 YMR066W Mitochondrial protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 2 1 1 Negative Genetic, Negative Genetic
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 genetic 2 1 1 Negative Genetic, Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 2 1 1 Negative Genetic, Negative Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 2 1 1 Negative Genetic, Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 2 1 1 Negative Genetic, Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 2 1 1 Negative Genetic, Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 2 1 1 Negative Genetic, Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 1 1 Negative Genetic, Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 2 1 1 Negative Genetic, Negative Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 1 Negative Genetic, Negative Genetic
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 1 1 Negative Genetic, Negative Genetic
AVT5 YBL089W Putative transporter genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Positive Genetic
AXL2 YIL140W Integral plasma membrane protein genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Negative Genetic
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 1 1 1 Positive Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 1 1 1 Positive Genetic
RSF2 YJR127C Zinc-finger protein physical 1 1 1 Affinity Capture-MS
NIS1 YNL078W Protein involved in axial bud site selection physical 1 1 1 Affinity Capture-MS
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
RPB4 YJL140W RNA polymerase II subunit B32 genetic 1 1 1 Positive Genetic
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Positive Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Reconstituted Complex
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
MRK1 YDL079C Glycogen synthase kinase 3 (GSK-3) homolog physical 1 1 1 Reconstituted Complex
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Reconstituted Complex
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Reconstituted Complex
SKS1 YPL026C Putative serine/threonine protein kinase physical 1 1 1 Reconstituted Complex
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Reconstituted Complex
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Protein-peptide
PRP40 YKL012W U1 snRNP protein involved in splicing physical 1 1 1 Protein-peptide
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ENT3 YJR125C Protein containing an N-terminal epsin-like domain physical 1 1 1 Reconstituted Complex
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 1 1 1 Synthetic Growth Defect
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Lethality
NPL6 YMR091C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Negative Genetic
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 1 1 1 Negative Genetic
VPS70 YJR126C Protein of unknown function involved in vacuolar protein sorting genetic 1 1 1 Negative Genetic
MND2 YIR025W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Positive Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Positive Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Positive Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Positive Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Positive Genetic
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Synthetic Growth Defect
JNM1 YMR294W Component of the yeast dynactin complex genetic 1 1 1 Synthetic Lethality
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Synthetic Rescue
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
PUS6 YGR169C tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
RBG2 YGR173W Protein with a role in translation genetic 1 1 1 Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Negative Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Positive Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Positive Genetic
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 1 1 1 Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Positive Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Positive Genetic
PCL7 YIL050W Pho85p cyclin of the Pho80p subfamily genetic 1 1 1 Negative Genetic
THI6 YPL214C Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase genetic 1 1 1 Positive Genetic
MSB2 YGR014W Mucin family member involved in various signaling pathways genetic 1 1 1 Dosage Rescue
KRS1 YDR037W Lysyl-tRNA synthetase genetic 1 1 1 Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
PHM8 YER037W Lysophosphatidic acid (LPA) phosphatase, nucleotidase genetic 1 1 1 Negative Genetic
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
YDR248C YDR248C Putative gluconokinase genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
FLO8 YER109C Transcription factor genetic 1 1 1 Negative Genetic
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 1 1 1 Negative Genetic
YFL051C YFL051C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ESL1 YIL151C hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YNL092W YNL092W S-adenosylmethionine-dependent protein methyltransferase genetic 1 1 1 Negative Genetic
REV1 YOR346W Deoxycytidyl transferase genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
NGG1 YDR176W Subunit of chromatin modifying histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
HHF1 YBR009C Histone H4 genetic 1 1 1 Positive Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Positive Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 1 1 1 Synthetic Lethality
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Positive Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Positive Genetic
RPL4B YDR012W Ribosomal 60S subunit protein L4B genetic 1 1 1 Positive Genetic
SOM1 YEL059C-A Subunit of the mitochondrial inner membrane peptidase (IMP) genetic 1 1 1 Positive Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Positive Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Positive Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Positive Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
POP5 YAL033W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Negative Genetic
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins genetic 1 1 1 Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 1 1 1 Negative Genetic
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Negative Genetic
YDR341C YDR341C Arginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
NSA1 YGL111W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
PHS1 YJL097W Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane genetic 1 1 1 Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
KAE1 YKR038C Highly conserved ATPase of HSP70/DnaK family genetic 1 1 1 Negative Genetic
TFA2 YKR062W TFIIE small subunit genetic 1 1 1 Negative Genetic
LAS1 YKR063C Endonuclease involved in pre-rRNA processing at both ends of ITS2 genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
TIM50 YPL063W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase genetic 1 1 1 Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
SPC110 YDR356W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PTH2 YBL057C One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi genetic 1 1 1 Negative Genetic
YPK3 YBR028C AGC kinase genetic 1 1 1 Negative Genetic
YSY6 YBR162W-A Protein of unknown function genetic 1 1 1 Negative Genetic
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p genetic 1 1 1 Negative Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 1 1 1 Negative Genetic
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein genetic 1 1 1 Negative Genetic
MFG1 YDL233W Regulator of filamentous growth genetic 1 1 1 Negative Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
MRX10 YDR282C Mitochondrial inner membrane protein of unknown function genetic 1 1 1 Negative Genetic
MSN5 YDR335W Karyopherin genetic 1 1 1 Negative Genetic
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Negative Genetic
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis genetic 1 1 1 Negative Genetic
YAT2 YER024W Carnitine acetyltransferase genetic 1 1 1 Negative Genetic
YFH7 YFR007W Putative kinase with similarity to the PRK/URK/PANK kinase subfamily genetic 1 1 1 Negative Genetic
YFR018C YFR018C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGL114W YGL114W Putative protein of unknown function genetic 1 1 1 Negative Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Negative Genetic
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
VVS1 YBR241C Putative transporter, member of the sugar porter family genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 1 1 1 Negative Genetic
MCH2 YKL221W Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 1 1 1 Negative Genetic
YNL108C YNL108C Protein phosphatase genetic 1 1 1 Negative Genetic
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
NEL1 YHR035W Activator of Sar1p GTPase activity genetic 1 1 1 Negative Genetic
PCL5 YHR071W Cyclin genetic 1 1 1 Negative Genetic
NOP10 YHR072W-A Subunit of box H/ACA snoRNP complex genetic 1 1 1 Negative Genetic
TDA11 YHR159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
YKL033W-A YKL033W-A Protein of unknown function genetic 1 1 1 Negative Genetic
ZRT3 YKL175W Vacuolar membrane zinc transporter genetic 1 1 1 Negative Genetic
YLL006W-A YLL006W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
MEU1 YLR017W Methylthioadenosine phosphorylase (MTAP) genetic 1 1 1 Negative Genetic
MLH2 YLR035C Protein involved in mismatch repair and meiotic recombination genetic 1 1 1 Negative Genetic
UPS2 YLR168C Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 1 1 1 Negative Genetic
SHH3 YMR118C Putative mitochondrial inner membrane protein of unknown function genetic 1 1 1 Negative Genetic
GID8 YMR135C Subunit of GID Complex, binds strongly to central component Vid30p genetic 1 1 1 Negative Genetic
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Negative Genetic
YMR206W YMR206W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR209C YMR209C Putative S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Negative Genetic
YNL190W YNL190W Hydrophilin essential in desiccation-rehydration process genetic 1 1 1 Negative Genetic
YTP1 YNL237W Probable type-III integral membrane protein of unknown function genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Negative Genetic
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Negative Genetic
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
YPL191C YPL191C K48-specific deubiquitinating (DUB) enzyme genetic 1 1 1 Negative Genetic
OXR1 YPL196W Protein involved in regulation of vacuolar V-ATPase genetic 1 1 1 Negative Genetic
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
YPR159C-A YPR159C-A Protein of unknown function genetic 1 1 1 Negative Genetic
SNL1 YIL016W Ribosome-associated protein genetic 1 1 1 Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs genetic 1 1 1 Positive Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
PRP8 YHR165C Component of U4/U6-U5 snRNP complex genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase genetic 1 1 1 Synthetic Lethality
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 1 1 1 Reconstituted Complex
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Positive Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
ECM10 YEL030W Heat shock protein of the Hsp70 family genetic 1 1 1 Negative Genetic
APT1 YML022W Adenine phosphoribosyltransferase genetic 1 1 1 Negative Genetic
ADD66 YKL206C Protein involved in 20S proteasome assembly genetic 1 1 1 Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Positive Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
DUT1 YBR252W Deoxyuridine triphosphate diphosphatase (dUTPase) genetic 1 1 1 Positive Genetic
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Reconstituted Complex
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ACA1 YER045C ATF/CREB family basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BMT5 YIL096C Methyltransferase required for m3U2634 methylation of the 25S rRNA physical 1 1 1 Affinity Capture-MS
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Lethality
BUD8 YLR353W Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Reconstituted Complex
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Negative Genetic
ACM1 YPL267W Pseudosubstrate inhibitor of the APC/C genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
ARR3 YPR201W Plasma membrane metalloid/H+ antiporter genetic 1 1 1 Negative Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Positive Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 1 1 1 Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 1 1 1 Negative Genetic
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Negative Genetic
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Negative Genetic
ALG13 YGL047W Catalytic component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
AST2 YER101C Lipid raft associated protein genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 1 1 1 Negative Genetic
ADY2 YCR010C Acetate transporter required for normal sporulation genetic 1 1 1 Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Positive Genetic