Standard name Systematic name Name description Description
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes Transcriptional repressor that regulates middle-sporulation genes; required for mitotic repression of middle sporulation-specific genes; also acts as general replication initiation factor; involved in telomere maintenance, chromatin silencing; regulated by pachytene checkpoint
Visualize the interactome of SUM1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 16

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.218 0.171 0.189
Nucleus 0.866 0.882 0.884
Mito NaN 0.254 0.549

GFP localization & abundance

GFP localization GFP abundance
nucleus 149

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SUM1 2 0 0 0 7

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 9 4 9 Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 8 2 5 Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HST1 YOL068C NAD(+)-dependent histone deacetylase physical 6 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 6 2 4 Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 6 2 4 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 6 2 4 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 5 2 5 Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression, Dosage Rescue, Phenotypic Suppression
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 5 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SIR3 YLR442C Silencing protein genetic 5 2 5 Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 5 3 4 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 5 3 4 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 5 2 4 Synthetic Haploinsufficiency, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 5 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 4 3 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Positive Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 4 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 4 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 4 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
SWC3 YAL011W Protein of unknown function genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 4 2 3 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 3 3 3 Synthetic Lethality, Phenotypic Suppression, Phenotypic Enhancement
ORC1 YML065W Largest subunit of the origin recognition complex genetic 3 2 3 Synthetic Rescue, Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
STB5 YHR178W Transcription factor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
YGL230C YGL230C Putative protein of unknown function regulation 3 3 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence, northern blot evidence
LEO1 YOR123C Component of the Paf1 complex genetic 3 2 2 Positive Genetic, Negative Genetic, Positive Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 3 2 2 Positive Genetic, Negative Genetic, Positive Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SNX4 YJL036W Sorting nexin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BNA1 YJR025C 3-hydroxyanthranilic acid dioxygenase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
DAL1 YIR027C Allantoinase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
PES4 YFR023W Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
OSW1 YOR255W Protein involved in sporulation regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SSP1 YHR184W Protein involved in the control of meiotic nuclear division regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
PHM6 YDR281C Protein of unknown function regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SPS22 YCL048W Protein of unknown function regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
HXT14 YNL318C Protein with similarity to hexose transporter family members regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
DTR1 YBR180W Putative dityrosine transporter of the major facilitator superfamily regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
YOR365C YOR365C Putative protein involved in sphingolipid biosynthesis regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
YDR042C YDR042C Putative protein of unknown function regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
YGL138C YGL138C Putative protein of unknown function regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
RRT5 YFR032C Putative protein of unknown function regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
YFL040W YFL040W Putative transporter regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
PFS1 YHR185C Sporulation protein required for prospore membrane formation regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
BNA2 YJR078W Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
CDC42 YLR229C Small rho-like GTPase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Negative Genetic, Dosage Lethality
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 2 2 Negative Genetic, Positive Genetic
HHF1 YBR009C Histone H4 genetic 2 2 2 Synthetic Rescue, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 2 2 2 Negative Genetic, Positive Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 2 2 2 Synthetic Lethality, Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Positive Genetic, Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
RFM1 YOR279C Component of the Sum1p-Rfm1p-Hst1p complex physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 2 2 Synthetic Lethality, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 2 2 2 Negative Genetic, Phenotypic Enhancement
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 2 Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 2 Negative Genetic, Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 1 2 Negative Genetic, Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 1 2 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 2 Negative Genetic, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 2 1 2 Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 2 1 2 Negative Genetic, Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 2 1 2 Negative Genetic, Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 2 1 2 Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 1 2 Positive Genetic, Positive Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 2 1 2 Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 1 2 Positive Genetic, Positive Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 2 1 2 Negative Genetic, Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 2 1 2 Negative Genetic, Negative Genetic
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion genetic 2 1 2 Negative Genetic, Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 2 1 2 Negative Genetic, Negative Genetic
MSO1 YNR049C Lipid-interacting protein in SNARE complex assembly machinery genetic 2 1 2 Negative Genetic, Negative Genetic
ORC5 YNL261W Subunit of the origin recognition complex (ORC) physical 2 1 2 Two-hybrid, Two-hybrid
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 2 Negative Genetic, Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 2 1 2 Positive Genetic, Positive Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 2 1 2 Negative Genetic, Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 2 1 2 Negative Genetic, Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 2 1 2 Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 2 1 2 Negative Genetic, Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
YCS4 YLR272C Subunit of the condensin complex genetic 2 1 2 Positive Genetic, Positive Genetic
SVL3 YPL032C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
TUB1 YML085C Alpha-tubulin genetic 2 1 2 Dosage Rescue, Dosage Rescue
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 2 1 2 Positive Genetic, Positive Genetic
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 2 1 2 Negative Genetic, Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 2 1 2 Negative Genetic, Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 2 1 2 Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 2 1 2 Positive Genetic, Positive Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 2 1 2 Negative Genetic, Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 2 1 2 Negative Genetic, Negative Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 2 1 2 Negative Genetic, Negative Genetic
RPI1 YIL119C Transcription factor, allelic differences between S288C and Sigma1278b regulation 2 2 1 chromatin immunoprecipitation-chip evidence, northern blot evidence
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 2 2 1 Negative Genetic, Positive Genetic
NPL3 YDR432W RNA-binding protein genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 2 1 Negative Genetic, Positive Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 2 1 Negative Genetic, Positive Genetic
SIZ1 YDR409W SUMO E3 ligase physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
ERV14 YGL054C COPII-coated vesicle protein genetic 2 2 1 Negative Genetic, Positive Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 2 2 1 Negative Genetic, Positive Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 2 2 1 Negative Genetic, Positive Genetic
PSF2 YJL072C Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 2 1 1 Negative Genetic, Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NOP2 YNL061W rRNA m5C methyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 2 1 1 Negative Genetic, Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 2 1 1 Negative Genetic, Negative Genetic
NOG2 YNR053C Putative GTPase genetic 2 1 1 Negative Genetic, Negative Genetic
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ERP2 YAL007C Member of the p24 family involved in ER to Golgi transport genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SLA1 YBL007C Cytoskeletal protein binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
PEP8 YJL053W Vacuolar protein component of the retromer genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
OST5 YGL226C-A Zeta subunit of the oligosaccharyltransferase complex of the ER lumen genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SIL1 YOL031C Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
PFY1 YOR122C Profilin genetic 2 1 1 Negative Genetic, Negative Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
GTB1 YDR221W Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
CWH41 YGL027C Processing alpha glucosidase I genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
YHR078W YHR078W High osmolarity-regulated gene of unknown function genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SVP26 YHR181W ER exit adaptor for Golgi mannosyltransferases genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
TED1 YIL039W GPI-glycan remodelase genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
TDA5 YLR426W Putative protein of unknown function genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
GOT1 YMR292W Homodimeric protein that is packaged into COPII vesicles genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
NEO1 YIL048W Phospholipid translocase (flippase) genetic 2 1 1 Negative Genetic, Negative Genetic
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
DIE2 YGR227W Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase genetic 2 1 1 Negative Genetic, Negative Genetic
ROT2 YBR229C Glucosidase II catalytic subunit genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
EMP65 YER140W Integral membrane protein of the ER genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SLP1 YOR154W Glycosylated integral ER membrane protein of unknown function genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GAS4 YOL132W 1,3-beta-glucanosyltransferase regulation 1 1 1 DNA to cDNA expression microarray evidence
GAS2 YLR343W 1,3-beta-glucanosyltransferase regulation 1 1 1 DNA to cDNA expression microarray evidence
GND2 YGR256W 6-phosphogluconate dehydrogenase (decarboxylating) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DAL4 YIR028W Allantoin permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TMC1 YOR052C AN1-type zinc finger protein, effector of proteotoxic stress response regulation 1 1 1 DNA to cDNA expression microarray evidence
ARG1 YOL058W Arginosuccinate synthetase regulation 1 1 1 DNA to cDNA expression microarray evidence
YPS1 YLR120C Aspartic protease regulation 1 1 1 DNA to cDNA expression microarray evidence
CMK2 YOL016C Calmodulin-dependent protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells regulation 1 1 1 DNA to cDNA expression microarray evidence
CDA2 YLR308W Chitin deacetylase regulation 1 1 1 DNA to cDNA expression microarray evidence
CDA1 YLR307W Chitin deacetylase regulation 1 1 1 DNA to cDNA expression microarray evidence
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPO74 YGL170C Component of the meiotic outer plaque of the spindle pole body regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body regulation 1 1 1 DNA to cDNA expression microarray evidence
SCP1 YOR367W Component of yeast cortical actin cytoskeleton regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIP1 YPL014W Cyclin-dependent kinase inhibitor regulation 1 1 1 DNA to cDNA expression microarray evidence
YPR077C YPR077C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YDL023C YDL023C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YGR259C YGR259C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR041W YLR041W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR364W YOR364W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR232W YLR232W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YNL319W YNL319W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YKL177W YKL177W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YNR064C YNR064C Epoxide hydrolase regulation 1 1 1 DNA to cDNA expression microarray evidence
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SEC63 YOR254C Essential subunit of Sec63 complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BIL2 YGL015C Formin inhibitor regulation 1 1 1 DNA to cDNA expression microarray evidence
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling regulation 1 1 1 DNA to cDNA expression microarray evidence
GYP6 YJL044C GTPase-activating protein (GAP) for yeast Rab family member Ypt6p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NRT1 YOR071C High-affinity nicotinamide riboside transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
PFS2 YNL317W Integral subunit of the pre-mRNA CPF complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BNA5 YLR231C Kynureninase regulation 1 1 1 DNA to cDNA expression microarray evidence
BNA4 YBL098W Kynurenine 3-monooxygenase regulation 1 1 1 DNA to cDNA expression microarray evidence
LSM2 YBL026W Lsm (Like Sm) protein regulation 1 1 1 northern blot evidence
FIT1 YDR534C Mannoprotein that is incorporated into the cell wall regulation 1 1 1 DNA to cDNA expression microarray evidence
AFB1 YLR040C MATalpha-specific a-factor blocker regulation 1 1 1 DNA to cDNA expression microarray evidence
MFA1 YDR461W Mating pheromone a-factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SMA2 YML066C Meiosis-specific prospore membrane protein regulation 1 1 1 DNA to cDNA expression microarray evidence
SPO19 YPL130W Meiosis-specific prospore protein regulation 1 1 1 DNA to cDNA expression microarray evidence
SPO77 YLR341W Meiosis-specific protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
SPO75 YLL005C Meiosis-specific protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
GIP1 YBR045C Meiosis-specific regulatory subunit of the Glc7p protein phosphatase regulation 1 1 1 DNA to cDNA expression microarray evidence
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) regulation 1 1 1 DNA to cDNA expression microarray evidence
MIR1 YJR077C Mitochondrial phosphate carrier regulation 1 1 1 chromatin immunoprecipitation-chip evidence
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) regulation 1 1 1 DNA to cDNA expression microarray evidence
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MAM1 YER106W Monopolin regulation 1 1 1 DNA to cDNA expression microarray evidence
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p regulation 1 1 1 DNA to cDNA expression microarray evidence
PHO11 YAR071W One of three repressible acid phosphatases regulation 1 1 1 DNA to cDNA expression microarray evidence
PHO12 YHR215W One of three repressible acid phosphatases regulation 1 1 1 DNA to cDNA expression microarray evidence
YAT1 YAR035W Outer mitochondrial carnitine acetyltransferase regulation 1 1 1 DNA to cDNA expression microarray evidence
PRM1 YNL279W Pheromone-regulated multispanning membrane protein regulation 1 1 1 DNA to cDNA expression microarray evidence
RCR1 YBR005W Plasma membrane (PM) ubiquitin ligase-substrate adaptor regulation 1 1 1 DNA to cDNA expression microarray evidence
PRM6 YML047C Potassium transporter that mediates K+ influx regulation 1 1 1 DNA to cDNA expression microarray evidence
LOH1 YJL038C Protein involved in outer spore wall assembly regulation 1 1 1 DNA to cDNA expression microarray evidence
LDS2 YOL047C Protein Involved in spore wall assembly regulation 1 1 1 DNA to cDNA expression microarray evidence
LDS1 YAL018C Protein Involved in spore wall assembly regulation 1 1 1 DNA to cDNA expression microarray evidence
SUA5 YGL169W Protein involved in threonylcarbamoyl adenosine biosynthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPO23 YBR250W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
DCV1 YFR012W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
DCG1 YIR030C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCN2 YOR220W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR272W-B YMR272W-B Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DIA1 YMR316W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
SRL4 YPL033C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YCL049C YCL049C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YHR127W YHR127W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR162W YLR162W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
SRL2 YLR082C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR257W YLR257W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR316C-A YMR316C-A Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
AIM17 YHL021C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YET3 YDL072C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
SPS18 YNL204C Protein of unknown function, contains a putative zinc-binding domain regulation 1 1 1 DNA to cDNA expression microarray evidence
SMA1 YPL027W Protein of unknown function involved in prospore membrane assembly regulation 1 1 1 DNA to cDNA expression microarray evidence
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YSW1 YBR148W Protein required for normal prospore membrane formation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AUA1 YFL010W-A Protein required for the negative regulation by ammonia of Gap1p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CRR1 YLR213C Putative glycoside hydrolase of the spore wall envelope regulation 1 1 1 DNA to cDNA expression microarray evidence
ANS1 YHR126C Putative GPI protein regulation 1 1 1 DNA to cDNA expression microarray evidence
YER085C YER085C Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR385W YOR385W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOL014W YOL014W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YJR079W YJR079W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOL024W YOL024W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR244W YMR244W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
FMP48 YGR052W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YFL012W YFL012W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YJL043W YJL043W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPR2 YOR214C Putative spore wall protein regulation 1 1 1 DNA to cDNA expression microarray evidence
YJR027W YJR027W Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YJR026W YJR026W Retrotransposon TYA Gag gene co-transcribed with TYB Pol regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAD2 YGR258C Single-stranded DNA endonuclease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SCS7 YMR272C Sphingolipid alpha-hydroxylase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPR1 YOR190W Sporulation-specific exo-1,3-beta-glucanase regulation 1 1 1 DNA to cDNA expression microarray evidence
SNZ1 YMR096W Subunit of a two-component pyridoxal-5'-phosphate synthase regulation 1 1 1 DNA to cDNA expression microarray evidence
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SAS5 YOR213C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MBF1 YOR298C-A Transcriptional coactivator regulation 1 1 1 DNA to cDNA expression microarray evidence
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCE1 YMR274C Type II CAAX prenyl protease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FRM2 YCL026C-A Type II nitroreductase, using NADH as reductant regulation 1 1 1 DNA to cDNA expression microarray evidence
UBC11 YOR339C Ubiquitin-conjugating enzyme regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
CHA4 YLR098C DNA binding transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Positive Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Positive Genetic
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex genetic 1 1 1 Dosage Rescue
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Positive Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Negative Genetic
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
RPC17 YJL011C RNA polymerase III subunit C17 genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Positive Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Positive Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
PUS1 YPL212C tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 1 1 1 Negative Genetic
ABD1 YBR236C Methyltransferase genetic 1 1 1 Negative Genetic
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Synthetic Lethality
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Positive Genetic
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Phenotypic Suppression
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Positive Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-Western
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Positive Genetic
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Synthetic Lethality
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Positive Genetic
SEC13 YLR208W Structural component of 3 complexes genetic 1 1 1 Negative Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Positive Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Positive Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 1 1 1 Affinity Capture-Western
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Two-hybrid
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Lethality
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Positive Genetic
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Positive Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Synthetic Rescue
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Positive Genetic
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase physical 1 1 1 Two-hybrid
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Positive Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Positive Genetic
ACO1 YLR304C Aconitase genetic 1 1 1 Negative Genetic
HEL2 YDR266C RING finger ubiquitin ligase (E3) genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ARF1 YDL192W ADP-ribosylation factor genetic 1 1 1 Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Negative Genetic
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Phenotypic Suppression
PKH2 YOL100W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
DMC1 YER179W Meiosis-specific recombinase required for double-strand break repair genetic 1 1 1 Phenotypic Enhancement
MRS6 YOR370C Rab escort protein genetic 1 1 1 Positive Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 1 1 1 Two-hybrid
SPO12 YHR152W Nucleolar protein of unknown function physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Positive Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
BEM3 YPL115C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Positive Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Positive Genetic
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 1 1 1 Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 1 1 1 Negative Genetic
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation genetic 1 1 1 Dosage Rescue
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Negative Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 1 1 1 Positive Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Positive Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Positive Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
DAP1 YPL170W Heme-binding protein genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Synthetic Lethality
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 1 1 1 Two-hybrid
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis physical 1 1 1 Biochemical Activity
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Positive Genetic
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Positive Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Positive Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 1 1 1 Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Positive Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
ALF1 YNL148C Alpha-tubulin folding protein genetic 1 1 1 Dosage Rescue
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Positive Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Positive Genetic
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway genetic 1 1 1 Negative Genetic
CBF2 YGR140W Essential kinetochore protein genetic 1 1 1 Positive Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-Western
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Phenotypic Enhancement
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Positive Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 1 1 1 Two-hybrid
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 1 1 1 Dosage Rescue
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Negative Genetic
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Positive Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Synthetic Growth Defect
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Dosage Rescue
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Positive Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Negative Genetic
NRT1 YOR071C High-affinity nicotinamide riboside transporter genetic 1 1 1 Synthetic Rescue
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Positive Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p genetic 1 1 1 Negative Genetic
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Positive Genetic
ORC5 YNL261W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Synthetic Lethality
SSO2 YMR183C Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
OAF1 YAL051W Oleate-activated transcription factor genetic 1 1 1 Phenotypic Suppression
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Positive Genetic
MATALPHA1 YCR040W Transcriptional co-activator that regulates mating-type-specific genes genetic 1 1 1 Phenotypic Suppression
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Positive Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Dosage Rescue
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Positive Genetic
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Negative Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Synthetic Rescue
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
SPC105 YGL093W Subunit of a kinetochore-microtubule binding complex genetic 1 1 1 Positive Genetic
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Negative Genetic
BPH1 YCR032W Protein homologous to Chediak-Higashi syndrome and Beige proteins genetic 1 1 1 Negative Genetic
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor genetic 1 1 1 Phenotypic Suppression
SPO75 YLL005C Meiosis-specific protein of unknown function genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
IPF1 YDL176W Protein of unknown function involved in actin patch formation genetic 1 1 1 Negative Genetic
NDT80 YHR124W Meiosis-specific transcription factor genetic 1 1 1 Phenotypic Enhancement
BAR1 YIL015W Aspartyl protease secreted to periplasmic space of mating type a cell genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Positive Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Negative Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Positive Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Positive Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Positive Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Positive Genetic
LCL1 YPL056C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Positive Genetic
NPR1 YNL183C Protein kinase genetic 1 1 1 Negative Genetic
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 1 1 1 Positive Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
PRY1 YJL079C Lipid binding protein genetic 1 1 1 Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Two-hybrid
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Positive Genetic
TPA1 YER049W Prolyl hydroxylase genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Synthetic Lethality
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Positive Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
YJL206C YJL206C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity genetic 1 1 1 Positive Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Positive Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 1 1 1 Negative Genetic
UTP9 YHR196W Nucleolar protein genetic 1 1 1 Negative Genetic
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
UBX6 YJL048C UBX (ubiquitin regulatory X) domain-containing protein genetic 1 1 1 Negative Genetic
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
YME2 YMR302C Integral inner mitochondrial membrane protein genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
YER010C YER010C Bifunctional HMG aldolase/oxaloacetate decarboxylase genetic 1 1 1 Negative Genetic
YFL012W YFL012W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Positive Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 1 1 1 Positive Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Positive Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Negative Genetic
YIP3 YNL044W Protein localized to COPII vesicles genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
RTC1 YOL138C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Positive Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Positive Genetic
MRL1 YPR079W Membrane protein genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Positive Genetic
SLM4 YBR077C Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Phenotypic Enhancement
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
RPL33A YPL143W Ribosomal 60S subunit protein L33A genetic 1 1 1 Positive Genetic
MXR2 YCL033C Methionine-R-sulfoxide reductase genetic 1 1 1 Positive Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
APS3 YJL024C Small subunit of the clathrin-associated adaptor complex AP-3 genetic 1 1 1 Negative Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Negative Genetic
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Negative Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
LCL3 YGL085W Putative protein of unknown function genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic