Standard name Systematic name Name description Description
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis
Visualize the interactome of FUS3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.230 0.214 0.179
Nucleus 0.204 0.227 0.294
Vac/Vac Memb 0.673 0.750 0.602

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 8480

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FUS3 0 0 0 4 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
STE7 YDL159W Signal transducing MAP kinase kinase physical 23 7 19 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, FRET, FRET, Biochemical Activity, Affinity Capture-MS, PCA, PCA, Two-hybrid, Biochemical Activity
STE5 YDR103W Pheromone-responsive MAPK scaffold protein physical 22 7 20 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Co-crystal Structure, FRET, FRET, Reconstituted Complex, FRET, Two-hybrid
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 12 5 9 Reconstituted Complex, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 9 3 9 Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 9 5 6 Reconstituted Complex, Two-hybrid, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Biochemical Activity, Biochemical Activity, Two-hybrid, Affinity Capture-MS
MSG5 YNL053W Dual-specificity protein phosphatase physical 6 5 6 Affinity Capture-MS, Co-localization, Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Two-hybrid
STE11 YLR362W Signal transducing MEK kinase physical 6 5 6 Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Co-fractionation, FRET, Two-hybrid
FAR1 YJL157C CDK inhibitor and nuclear anchor physical 5 3 4 Biochemical Activity, Biochemical Activity, Biochemical Activity, Reconstituted Complex, Co-crystal Structure
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression physical 5 3 4 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Affinity Capture-MS
GPA1 YHR005C Subunit of G protein involved in pheromone response physical 5 3 3 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Co-localization, Affinity Capture-Western
PTP3 YER075C Phosphotyrosine-specific protein phosphatase physical 5 4 2 Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Biochemical Activity, Biochemical Activity
GPA1 YHR005C Subunit of G protein involved in pheromone response genetic 4 3 4 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 3 3 3 Phenotypic Enhancement, Positive Genetic, Phenotypic Suppression
RAS2 YNL098C GTP-binding protein genetic 3 3 3 Phenotypic Enhancement, Positive Genetic, Phenotypic Suppression
STE4 YOR212W G protein beta subunit genetic 3 3 3 Phenotypic Enhancement, Synthetic Rescue, Phenotypic Suppression
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 3 3 3 Phenotypic Enhancement, Phenotypic Suppression, Negative Genetic
CLN3 YAL040C G1 cyclin involved in cell cycle progression genetic 3 3 3 Phenotypic Suppression, Phenotypic Enhancement, Positive Genetic
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade physical 3 2 3 Biochemical Activity, Biochemical Activity, Affinity Capture-MS
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 3 2 3 Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 3 2 3 Biochemical Activity, FRET, Biochemical Activity
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 3 2 3 Negative Genetic, Phenotypic Enhancement, Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
FPK1 YNR047W Ser/Thr protein kinase genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
STE11 YLR362W Signal transducing MEK kinase genetic 3 1 3 Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor physical 3 3 1 Affinity Capture-Western, Reconstituted Complex, Biochemical Activity
MPT5 YGL178W mRNA-binding protein of the PUF family physical 3 2 1 Affinity Capture-Western, Two-hybrid, Two-hybrid
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 2 2 2 Phenotypic Enhancement, Positive Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Rescue, Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 2 2 2 Biochemical Activity, Affinity Capture-MS
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 2 2 2 Synthetic Lethality, Phenotypic Suppression
ELM1 YKL048C Serine/threonine protein kinase genetic 2 2 2 Negative Genetic, Phenotypic Enhancement
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 2 2 2 Biochemical Activity, Affinity Capture-MS
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 2 2 2 Positive Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 2 2 Positive Genetic, Phenotypic Suppression
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 2 2 2 Negative Genetic, Positive Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 2 2 2 Negative Genetic, Positive Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 2 2 2 Phenotypic Suppression, Positive Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 2 2 2 Positive Genetic, Phenotypic Enhancement
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
ALR1 YOL130W Plasma membrane Mg(2+) transporter physical 2 2 2 Biochemical Activity, Affinity Capture-MS
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 2 1 2 Positive Genetic, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 2 1 2 Positive Genetic, Positive Genetic
RCK1 YGL158W Protein kinase involved in oxidative stress response physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
STE5 YDR103W Pheromone-responsive MAPK scaffold protein genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 2 1 2 Biochemical Activity, Biochemical Activity
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 2 1 2 Negative Genetic, Negative Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 2 1 2 Negative Genetic, Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 2 1 2 Negative Genetic, Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 2 1 2 Positive Genetic, Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 1 2 Positive Genetic, Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 2 Positive Genetic, Positive Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 1 2 Positive Genetic, Positive Genetic
YVH1 YIR026C Dual specificity protein phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 1 2 Positive Genetic, Positive Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 2 1 2 Positive Genetic, Positive Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Positive Genetic, Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 1 2 Positive Genetic, Positive Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 2 1 2 Positive Genetic, Positive Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 2 1 2 Positive Genetic, Positive Genetic
BAS1 YKR099W Myb-related transcription factor genetic 2 1 2 Positive Genetic, Positive Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 1 2 Positive Genetic, Positive Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Positive Genetic, Positive Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 2 1 2 Positive Genetic, Positive Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 2 2 1 Reconstituted Complex, Biochemical Activity
MIH1 YMR036C Protein tyrosine phosphatase genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase physical 2 1 1 Reconstituted Complex, Reconstituted Complex
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family regulation 1 1 1 RNA-sequencing evidence
SIR3 YLR442C Silencing protein regulation 1 1 1 RNA-sequencing evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains regulation 1 1 1 RNA-sequencing evidence
PUT3 YKL015W Transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FUS2 YMR232W Cell fusion regulator regulation 1 1 1 protein kinase assay evidence
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p regulation 1 1 1 electrophoretic mobility shift assay evidence
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating regulation 1 1 1 protein kinase assay evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Synthetic Rescue
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Positive Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Haploinsufficiency
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Positive Genetic
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme genetic 1 1 1 Positive Genetic
BEM1 YBR200W Protein containing SH3-domains physical 1 1 1 Affinity Capture-Western
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Dosage Rescue
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Positive Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Phenotypic Suppression
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Synthetic Growth Defect
BNI1 YNL271C Formin physical 1 1 1 Biochemical Activity
BNI1 YNL271C Formin genetic 1 1 1 Dosage Rescue
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Synthetic Growth Defect
ELP2 YGR200C Subunit of Elongator complex physical 1 1 1 Reconstituted Complex
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Positive Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 Biochemical Activity
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 1 1 1 Affinity Capture-MS
BDF2 YDL070W Protein involved in transcription initiation physical 1 1 1 Biochemical Activity
BDF2 YDL070W Protein involved in transcription initiation genetic 1 1 1 Positive Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Biochemical Activity
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
FUN19 YAL034C Non-essential protein of unknown function physical 1 1 1 Biochemical Activity
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 Affinity Capture-MS
CMS1 YLR003C Putative subunit of the 90S preribosome processome complex physical 1 1 1 Biochemical Activity
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor physical 1 1 1 Affinity Capture-MS
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 1 1 1 Positive Genetic
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Positive Genetic
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization genetic 1 1 1 Negative Genetic
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Synthetic Rescue
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
ERG1 YGR175C Squalene epoxidase genetic 1 1 1 Negative Genetic
ARE2 YNR019W Acyl-CoA:sterol acyltransferase physical 1 1 1 Biochemical Activity
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 1 1 1 Negative Genetic
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis physical 1 1 1 Reconstituted Complex
FAA2 YER015W Medium chain fatty acyl-CoA synthetase genetic 1 1 1 Negative Genetic
AHC1 YOR023C Subunit of the Ada histone acetyltransferase complex genetic 1 1 1 Positive Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Positive Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Positive Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Synthetic Rescue
STE7 YDL159W Signal transducing MAP kinase kinase genetic 1 1 1 Phenotypic Suppression
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 Affinity Capture-Western
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
HSP60 YLR259C Tetradecameric mitochondrial chaperonin physical 1 1 1 Affinity Capture-MS
VPS75 YNL246W NAP family histone chaperone physical 1 1 1 Affinity Capture-MS
MCM2 YBL023C Protein involved in DNA replication physical 1 1 1 Biochemical Activity
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 Biochemical Activity
OLE1 YGL055W Delta(9) fatty acid desaturase physical 1 1 1 Biochemical Activity
UTP7 YER082C Nucleolar protein physical 1 1 1 Biochemical Activity
TOM71 YHR117W Mitochondrial outer membrane protein physical 1 1 1 Biochemical Activity
NOP53 YPL146C Nucleolar protein physical 1 1 1 Biochemical Activity
YMR262W YMR262W Protein of unknown function physical 1 1 1 Biochemical Activity
YGR237C YGR237C Putative protein of unknown function physical 1 1 1 Biochemical Activity
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis physical 1 1 1 Biochemical Activity
YOL103W-A YOL103W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator physical 1 1 1 Biochemical Activity
LOA1 YPR139C Lysophosphatidic acid acyltransferase physical 1 1 1 Biochemical Activity
PTH2 YBL057C One of two mitochondrially-localized peptidyl-tRNA hydrolases physical 1 1 1 Biochemical Activity
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Biochemical Activity
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 1 1 1 Biochemical Activity
YHR214C-C YHR214C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
RDS2 YPL133C Transcription factor involved in regulating gluconeogenesis physical 1 1 1 Biochemical Activity
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 1 1 1 Biochemical Activity
UBP9 YER098W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Biochemical Activity
TRM1 YDR120C tRNA methyltransferase physical 1 1 1 Biochemical Activity
YPR158C-C YPR158C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p physical 1 1 1 Biochemical Activity
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Positive Genetic
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis physical 1 1 1 Biochemical Activity
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties physical 1 1 1 Biochemical Activity
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YHR131C YHR131C Putative protein of unknown function physical 1 1 1 Biochemical Activity
YBL055C YBL055C 3'-->5' exonuclease and endonuclease with a possible role in apoptosis physical 1 1 1 Biochemical Activity
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase physical 1 1 1 Biochemical Activity
YNL054W-A YNL054W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YPL257W-A YPL257W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) physical 1 1 1 Biochemical Activity
YPR158W-A YPR158W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Biochemical Activity
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 1 1 1 Biochemical Activity
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Biochemical Activity
YNL284C-A YNL284C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
YDR034C-C YDR034C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
MAK10 YEL053C Non-catalytic subunit of the NatC N-terminal acetyltransferase physical 1 1 1 Biochemical Activity
HEL2 YDR266C RING finger ubiquitin ligase (E3) physical 1 1 1 Biochemical Activity
YML045W-A YML045W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
MCM3 YEL032W Protein involved in DNA replication physical 1 1 1 Biochemical Activity
PRP6 YBR055C Splicing factor physical 1 1 1 Biochemical Activity
PAR32 YDL173W Low complexity protein physical 1 1 1 Biochemical Activity
MSB3 YNL293W Rab GTPase-activating protein physical 1 1 1 Biochemical Activity
YGR027W-A YGR027W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Biochemical Activity
TMA22 YJR014W Protein of unknown function physical 1 1 1 Biochemical Activity
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein physical 1 1 1 Biochemical Activity
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Biochemical Activity
YGL082W YGL082W Putative protein of unknown function physical 1 1 1 Biochemical Activity
IFM1 YOL023W Mitochondrial translation initiation factor 2 physical 1 1 1 Biochemical Activity
GIR2 YDR152W Highly-acidic RWD domain-containing cytoplasmic protein physical 1 1 1 Biochemical Activity
OSW7 YFR039C Protein involved in outer spore wall assembly physical 1 1 1 Biochemical Activity
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) physical 1 1 1 Biochemical Activity
YBR259W YBR259W Protein of unknown function physical 1 1 1 Biochemical Activity
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Biochemical Activity
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Negative Genetic
LYS9 YNR050C Saccharopine dehydrogenase (NADP+, L-glutamate-forming) physical 1 1 1 Biochemical Activity
HTA1 YDR225W Histone H2A physical 1 1 1 Biochemical Activity
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Biochemical Activity
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Two-hybrid
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Positive Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-Western
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-Western
NAB6 YML117W Putative RNA-binding protein physical 1 1 1 Affinity Capture-MS
NET1 YJL076W Core subunit of the RENT complex physical 1 1 1 Affinity Capture-MS
YMR295C YMR295C Protein of unknown function that associates with ribosomes physical 1 1 1 Affinity Capture-MS
GAL10 YBR019C UDP-glucose-4-epimerase physical 1 1 1 Reconstituted Complex
MTD1 YKR080W NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase physical 1 1 1 Reconstituted Complex
TRP3 YKL211C Indole-3-glycerol-phosphate synthase physical 1 1 1 Reconstituted Complex
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 1 1 1 Affinity Capture-RNA
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-RNA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SST2 YLR452C GTPase-activating protein for Gpa1p physical 1 1 1 Biochemical Activity
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 Biochemical Activity
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Negative Genetic
SPA2 YLL021W Component of the polarisome physical 1 1 1 Affinity Capture-Western
HHF1 YBR009C Histone H4 physical 1 1 1 Biochemical Activity
PTA1 YAL043C Subunit of holo-CPF genetic 1 1 1 Negative Genetic
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Negative Genetic
HOP2 YGL033W Meiosis-specific protein that localizes to chromosomes genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 genetic 1 1 1 Negative Genetic
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 genetic 1 1 1 Negative Genetic
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 1 1 1 Negative Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Negative Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Negative Genetic
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 1 1 1 Negative Genetic
RAD24 YER173W Checkpoint protein genetic 1 1 1 Negative Genetic
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
MGS1 YNL218W Protein with DNA-dependent ATPase and ssDNA annealing activities genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Positive Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Positive Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Positive Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Positive Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Positive Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Growth Defect
YAK1 YJL141C Serine-threonine protein kinase genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Positive Genetic
GAL1 YBR020W Galactokinase genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
GCN2 YDR283C Protein kinase genetic 1 1 1 Negative Genetic
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Negative Genetic
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Negative Genetic
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Synthetic Rescue
PGK1 YCR012W 3-phosphoglycerate kinase genetic 1 1 1 Dosage Rescue
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Positive Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Positive Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Positive Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif genetic 1 1 1 Positive Genetic
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family genetic 1 1 1 Positive Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Positive Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Positive Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Negative Genetic
GAT2 YMR136W Protein containing GATA family zinc finger motifs genetic 1 1 1 Negative Genetic
NRG2 YBR066C Transcriptional repressor genetic 1 1 1 Negative Genetic
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
PTC3 YBL056W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
PUT3 YKL015W Transcriptional activator genetic 1 1 1 Negative Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
UPC2 YDR213W Sterol regulatory element binding protein genetic 1 1 1 Positive Genetic
PPN2 YNL217W Zn2+-dependent endopolyphosphatase genetic 1 1 1 Positive Genetic
SPS18 YNL204C Protein of unknown function, contains a putative zinc-binding domain genetic 1 1 1 Positive Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Positive Genetic
PSY4 YBL046W Regulatory subunit of protein phosphatase PP4 genetic 1 1 1 Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
RIM11 YMR139W Protein kinase genetic 1 1 1 Negative Genetic
GZF3 YJL110C GATA zinc finger protein genetic 1 1 1 Negative Genetic
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Positive Genetic
PMD1 YER132C Protein with an N-terminal kelch-like domain genetic 1 1 1 Dosage Growth Defect
MSW1 YDR268W Mitochondrial tryptophanyl-tRNA synthetase genetic 1 1 1 Dosage Growth Defect
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Dosage Growth Defect
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Phenotypic Enhancement
STE18 YJR086W G protein gamma subunit genetic 1 1 1 Phenotypic Suppression
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Suppression
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Synthetic Growth Defect
KIN2 YLR096W S/T protein kinase genetic 1 1 1 Positive Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Positive Genetic
NMA111 YNL123W Serine protease and general molecular chaperone genetic 1 1 1 Positive Genetic
GAP1 YKR039W General amino acid permease genetic 1 1 1 Negative Genetic
URA10 YMR271C Minor orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Positive Genetic
TSC10 YBR265W 3-ketosphinganine reductase genetic 1 1 1 Positive Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
PHO5 YBR093C Repressible acid phosphatase genetic 1 1 1 Negative Genetic
YAT1 YAR035W Outer mitochondrial carnitine acetyltransferase genetic 1 1 1 Positive Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Negative Genetic
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Positive Genetic
YPK9 YOR291W Vacuolar protein with a possible role in sequestering heavy metals genetic 1 1 1 Positive Genetic
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase genetic 1 1 1 Negative Genetic
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting genetic 1 1 1 Positive Genetic
RIM2 YBR192W Mitochondrial pyrimidine nucleotide transporter genetic 1 1 1 Negative Genetic
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Positive Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Positive Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Positive Genetic
SAH1 YER043C S-adenosyl-L-homocysteine hydrolase genetic 1 1 1 Negative Genetic
NOG1 YPL093W Putative GTPase genetic 1 1 1 Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 1 1 1 Negative Genetic
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform genetic 1 1 1 Negative Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Negative Genetic
PRK1 YIL095W Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Positive Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
MAP1 YLR244C Methionine aminopeptidase genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
RAM2 YKL019W Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I genetic 1 1 1 Positive Genetic
TUM1 YOR251C Rhodanese domain sulfur transferase genetic 1 1 1 Positive Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
YMC1 YPR058W Secondary mitochondrial inner membrane glycine transporter genetic 1 1 1 Positive Genetic
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 1 1 1 Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 1 1 1 Positive Genetic
RPC40 YPR110C RNA polymerase subunit AC40 genetic 1 1 1 Positive Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Positive Genetic
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
HRK1 YOR267C Protein kinase genetic 1 1 1 Positive Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Negative Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
YIM1 YMR152W Aldehyde reductase genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Positive Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Positive Genetic
HEM25 YDL119C Mitochondrial glycine transporter genetic 1 1 1 Positive Genetic
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Negative Genetic
TAT2 YOL020W High affinity tryptophan and tyrosine permease genetic 1 1 1 Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Positive Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin genetic 1 1 1 Negative Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Positive Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Positive Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Negative Genetic
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Positive Genetic
PTR2 YKR093W Integral membrane peptide transporter genetic 1 1 1 Negative Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Positive Genetic
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Positive Genetic
RAD23 YEL037C Protein with ubiquitin-like N terminus genetic 1 1 1 Positive Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Positive Genetic
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 1 1 1 Positive Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Positive Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Positive Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Negative Genetic
IRA1 YBR140C GTPase-activating protein genetic 1 1 1 Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Positive Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
TFB3 YDR460W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SHH3 YMR118C Putative mitochondrial inner membrane protein of unknown function genetic 1 1 1 Positive Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Positive Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Positive Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Biochemical Activity
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Phenotypic Suppression
FAR3 YMR052W Protein of unknown function genetic 1 1 1 Phenotypic Enhancement
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Positive Genetic
CHA4 YLR098C DNA binding transcriptional activator genetic 1 1 1 Negative Genetic
ESL1 YIL151C hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Synthetic Growth Defect
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Positive Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Positive Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
ELO3 YLR372W Elongase genetic 1 1 1 Positive Genetic
CST9 YLR394W SUMO E3 ligase physical 1 1 1 Biochemical Activity
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Negative Genetic
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Synthetic Rescue
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase physical 1 1 1 Biochemical Activity
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Enhancement
ENT5 YDR153C Protein containing an N-terminal epsin-like domain physical 1 1 1 Biochemical Activity
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Negative Genetic
FLO8 YER109C Transcription factor genetic 1 1 1 Phenotypic Suppression
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 1 1 1 Biochemical Activity
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Positive Genetic
APM2 YHL019C Protein of unknown function physical 1 1 1 Biochemical Activity
CAT2 YML042W Carnitine acetyl-CoA transferase genetic 1 1 1 Positive Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Negative Genetic
CRS1 YNL247W Cysteinyl-tRNA synthetase genetic 1 1 1 Positive Genetic
FIG2 YCR089W Cell wall adhesin, expressed specifically during mating genetic 1 1 1 Phenotypic Suppression
COA4 YLR218C Twin Cx(9)C protein involved in cytochrome c oxidase organization genetic 1 1 1 Negative Genetic
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 1 1 1 Negative Genetic
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 1 1 1 Positive Genetic
CUP9 YPL177C Homeodomain-containing transcriptional repressor genetic 1 1 1 Negative Genetic
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
CMR3 YPR013C Putative zinc finger protein genetic 1 1 1 Positive Genetic
ERG12 YMR208W Mevalonate kinase genetic 1 1 1 Negative Genetic
DLT1 YMR126C Protein of unknown function genetic 1 1 1 Positive Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 1 1 1 Positive Genetic
AIM33 YML087C Protein of unknown function, highly conserved across species genetic 1 1 1 Positive Genetic
CAX4 YGR036C Dolichyl pyrophosphate (Dol-P-P) phosphatase genetic 1 1 1 Positive Genetic