Standard name Systematic name Name description Description
CDC14 YFR028C Protein phosphatase required for mitotic exit Protein phosphatase required for mitotic exit; required for rDNA segregation, cytokinesis, meiosis I spindle disassembly, environmental stress response; held in nucleolus by Cdc55p in early meiosis, liberated by FEAR and Mitotic Exit Network in anaphase, enabling it to effect a decrease in CDK/B-cyclin activity and mitotic exit; sequestered in metaphase II, released upon entry into anaphase II; human homolog CDC14A can complement thermosensitivity of yeast cdc14-1 mutant
Visualize the interactome of CDC14
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 146

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.133 NaN NaN
Nucleolus 0.727 0.727 0.678
Nucleus 0.186 0.202 0.121
SpindlePole 0.216 0.270 0.441
Vac/Vac Memb NaN 0.057 NaN

GFP localization & abundance

GFP localization GFP abundance
nucleolus 8550

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CDC14 3 3 3 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
NET1 YJL076W Core subunit of the RENT complex physical 29 5 19 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 17 6 13 Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Dosage Rescue, Dosage Rescue, Negative Genetic, Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect, Dosage Rescue, Dosage Rescue, Phenotypic Suppression, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 11 6 9 Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Growth Defect, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 11 5 9 Dosage Rescue, Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 8 6 6 Dosage Lethality, Synthetic Lethality, Negative Genetic, Phenotypic Enhancement, Synthetic Rescue, Phenotypic Suppression, Negative Genetic, Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 8 3 6 Dosage Rescue, Dosage Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Dosage Rescue, Negative Genetic, Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 6 4 6 Dosage Rescue, Synthetic Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Rescue
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 6 4 5 Dosage Rescue, Synthetic Rescue, Synthetic Lethality, Negative Genetic, Synthetic Rescue, Synthetic Rescue
SLK19 YOR195W Kinetochore-associated protein genetic 6 4 5 Synthetic Rescue, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) physical 6 5 4 Affinity Capture-Western, Two-hybrid, Co-localization, Reconstituted Complex, Affinity Capture-MS, Two-hybrid
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 6 4 4 Affinity Capture-Western, Co-crystal Structure, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Reconstituted Complex
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 6 4 4 Synthetic Growth Defect, Dosage Lethality, Synthetic Growth Defect, Dosage Rescue, Negative Genetic, Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p physical 6 5 3 Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Biochemical Activity, Two-hybrid, Affinity Capture-MS
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 6 4 3 Affinity Capture-MS, Affinity Capture-Western, Co-crystal Structure, Protein-peptide, Affinity Capture-Western, Affinity Capture-Western
ACM1 YPL267W Pseudosubstrate inhibitor of the APC/C physical 6 2 3 Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Biochemical Activity
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 5 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 5 4 4 Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation physical 5 4 4 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 5 3 4 Synthetic Lethality, Synthetic Lethality, Dosage Lethality, Negative Genetic, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) physical 5 5 3 Reconstituted Complex, Biochemical Activity, Affinity Capture-MS, Co-crystal Structure, Protein-peptide
ORC6 YHR118C Subunit of the origin recognition complex (ORC) physical 5 3 3 Affinity Capture-Western, Two-hybrid, Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western
INN1 YNL152W Essential protein that associates with contractile actomyosin ring physical 5 4 2 Two-hybrid, Two-hybrid, Reconstituted Complex, Biochemical Activity, PCA
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 4 3 4 Co-localization, Biochemical Activity, Affinity Capture-MS, Biochemical Activity
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 4 3 3 Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
SPO12 YHR152W Nucleolar protein of unknown function genetic 4 3 3 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 4 2 3 Negative Genetic, Phenotypic Suppression, Negative Genetic, Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 4 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 4 2 3 Dosage Lethality, Dosage Lethality, Negative Genetic, Negative Genetic
YEN1 YER041W Holliday junction resolvase physical 4 2 2 Biochemical Activity, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 3 3 3 Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 3 3 3 Dosage Lethality, Synthetic Growth Defect, Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 3 3 3 Synthetic Lethality, Phenotypic Suppression, Negative Genetic
BUB2 YMR055C Mitotic exit network regulator physical 3 3 3 Affinity Capture-Western, Co-localization, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
NET1 YJL076W Core subunit of the RENT complex genetic 3 2 3 Dosage Rescue, Synthetic Rescue, Dosage Rescue
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I physical 3 2 3 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 3 2 3 Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement
RPA12 YJR063W RNA polymerase I subunit A12.2 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
KAR9 YPL269W Spindle positioning factor physical 3 3 2 Affinity Capture-MS, Reconstituted Complex, Protein-peptide
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication physical 3 3 2 Affinity Capture-MS, Two-hybrid, Biochemical Activity
BUD3 YCL014W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 3 3 2 Affinity Capture-MS, Reconstituted Complex, Biochemical Activity
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 3 2 2 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
CDC6 YJL194W Essential ATP-binding protein required for DNA replication physical 3 2 2 Affinity Capture-Western, Biochemical Activity, Biochemical Activity
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 3 2 2 Phenotypic Suppression, Negative Genetic, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 3 3 1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid
ORC2 YBR060C Subunit of the origin recognition complex (ORC) physical 3 3 1 Affinity Capture-Western, Two-hybrid, Biochemical Activity
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
SWI6 YLR182W Transcription cofactor physical 2 2 2 Biochemical Activity, Co-crystal Structure
LTE1 YAL024C Protein similar to GDP/GTP exchange factors physical 2 2 2 Biochemical Activity, Affinity Capture-MS
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 2 2 2 Co-localization, Affinity Capture-MS
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
YDL129W YDL129W Protein of unknown function physical 2 2 2 Two-hybrid, Affinity Capture-MS
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA physical 2 2 2 Two-hybrid, Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 2 2 2 Two-hybrid, Biochemical Activity
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Synthetic Rescue, Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
CLB3 YDL155W B-type cyclin involved in cell cycle progression genetic 2 2 2 Phenotypic Enhancement, Synthetic Lethality
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity genetic 2 2 2 Phenotypic Enhancement, Positive Genetic
MCM3 YEL032W Protein involved in DNA replication genetic 2 2 2 Dosage Lethality, Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 2 2 2 Phenotypic Suppression, Negative Genetic
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
NUR1 YDL089W Protein involved in regulation of mitotic exit physical 2 2 2 Biochemical Activity, Two-hybrid
ORC5 YNL261W Subunit of the origin recognition complex (ORC) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 2 2 2 Synthetic Lethality, Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 2 2 2 Dosage Lethality, Phenotypic Suppression
CHL1 YPL008W Probable DNA helicase genetic 2 2 2 Negative Genetic, Synthetic Lethality
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 2 2 2 Phenotypic Suppression, Synthetic Lethality
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
BUB2 YMR055C Mitotic exit network regulator genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 2 2 Synthetic Lethality, Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RIF1 YBR275C Protein involved in control of DNA replication physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SAC3 YDR159W mRNA export factor genetic 2 1 2 Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
INO2 YDR123C Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector physical 2 2 1 Reconstituted Complex, Two-hybrid
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
STE7 YDL159W Signal transducing MAP kinase kinase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
CLB3 YDL155W B-type cyclin involved in cell cycle progression physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
FMP48 YGR052W Putative protein of unknown function physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
MET14 YKL001C Adenylylsulfate kinase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
SNF1 YDR477W AMP-activated S/T protein kinase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
MCM3 YEL032W Protein involved in DNA replication physical 2 2 1 Affinity Capture-Western, Biochemical Activity
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint physical 2 2 1 Affinity Capture-MS, Reconstituted Complex
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 2 2 1 Affinity Capture-MS, Reconstituted Complex
LRE1 YCL051W Protein involved in control of cell wall structure and stress response physical 2 2 1 Two-hybrid, Biochemical Activity
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation physical 2 2 1 Affinity Capture-Western, Biochemical Activity
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 2 2 1 Co-crystal Structure, Reconstituted Complex
HSP82 YPL240C Hsp90 chaperone physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
SEC4 YFL005W Rab family GTPase physical 2 2 1 Affinity Capture-MS, Two-hybrid
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 2 2 1 Synthetic Lethality, Phenotypic Suppression
YJR120W YJR120W Protein of unknown function genetic 2 2 1 Positive Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 2 2 1 Positive Genetic, Negative Genetic
RSA1 YPL193W Protein involved in the assembly of 60S ribosomal subunits genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
HIT1 YJR055W Protein involved in C/D snoRNP assembly genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
BNI1 YNL271C Formin physical 2 2 1 Affinity Capture-MS, Reconstituted Complex
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
BNR1 YIL159W Formin physical 2 2 1 Affinity Capture-MS, Reconstituted Complex
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein physical 2 2 1 Two-hybrid, Biochemical Activity
HSL1 YKL101W Nim1p-related protein kinase genetic 2 1 1 Negative Genetic, Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
MCM2 YBL023C Protein involved in DNA replication genetic 2 1 1 Negative Genetic, Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 1 Negative Genetic, Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 2 1 1 Negative Genetic, Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 1 1 Negative Genetic, Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 1 1 Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 2 1 1 Negative Genetic, Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 2 1 1 Negative Genetic, Negative Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 2 1 1 Negative Genetic, Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 2 1 1 Negative Genetic, Negative Genetic
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 1 1 Negative Genetic, Negative Genetic
PFY1 YOR122C Profilin genetic 2 1 1 Negative Genetic, Negative Genetic
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes genetic 2 1 1 Negative Genetic, Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
BRN1 YBL097W Subunit of the condensin complex genetic 2 1 1 Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
IQG1 YPL242C Actin filament binding protein that enhances actin ring formation regulation 1 1 1 qualitative western immunoblotting evidence
SFI1 YLL003W Centrin (Cdc31p)-binding protein required for SPB duplication regulation 1 1 1 phosphatase assay evidence
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex regulation 1 1 1 qualitative western immunoblotting evidence
FIN1 YDR130C Spindle pole body-related intermediate filament protein regulation 1 1 1 phosphatase assay evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
APC2 YLR127C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p genetic 1 1 1 Negative Genetic
FUR1 YHR128W Uracil phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
HMS1 YOR032C bHLH protein with similarity to myc-family transcription factors physical 1 1 1 Affinity Capture-MS
SPE3 YPR069C Spermidine synthase physical 1 1 1 Affinity Capture-MS
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex physical 1 1 1 Affinity Capture-MS
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
HEF3 YNL014W Translational elongation factor EF-3 physical 1 1 1 Affinity Capture-MS
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 1 1 1 Affinity Capture-MS
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 1 1 1 Affinity Capture-MS
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase physical 1 1 1 Affinity Capture-MS
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane physical 1 1 1 Affinity Capture-MS
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex physical 1 1 1 Affinity Capture-MS
TSA2 YDR453C Stress inducible cytoplasmic thioredoxin peroxidase physical 1 1 1 Affinity Capture-MS
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site genetic 1 1 1 Phenotypic Enhancement
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 1 1 1 Co-localization
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Enhancement
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 1 1 1 Biochemical Activity
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 Affinity Capture-MS
SLD2 YKL108W Single-stranded DNA origin-binding and annealing protein physical 1 1 1 Biochemical Activity
TPD3 YAL016W Regulatory subunit A of the heterotrimeric PP2A complex physical 1 1 1 Two-hybrid
PUP3 YER094C Beta 3 subunit of the 20S proteasome physical 1 1 1 Two-hybrid
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
YER158C YER158C Protein of unknown function physical 1 1 1 Two-hybrid
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p physical 1 1 1 Two-hybrid
UTP7 YER082C Nucleolar protein physical 1 1 1 Affinity Capture-Western
UTP7 YER082C Nucleolar protein genetic 1 1 1 Synthetic Rescue
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Dosage Rescue
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-MS
RBL2 YOR265W Protein involved in microtubule morphogenesis physical 1 1 1 Affinity Capture-MS
RRN10 YBL025W Protein involved in promoting high level transcription of rDNA physical 1 1 1 Affinity Capture-MS
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-MS
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-MS
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
YDR239C YDR239C Protein of unknown function physical 1 1 1 Affinity Capture-MS
CMR2 YOR093C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase physical 1 1 1 Affinity Capture-MS
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation physical 1 1 1 Affinity Capture-MS
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Affinity Capture-MS
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint physical 1 1 1 Affinity Capture-MS
KIN2 YLR096W S/T protein kinase physical 1 1 1 Affinity Capture-MS
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway physical 1 1 1 Affinity Capture-MS
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Synthetic Rescue
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
PSR2 YLR019W Putative plasma membrane phosphatase physical 1 1 1 Affinity Capture-MS
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase physical 1 1 1 Affinity Capture-MS
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Phenotypic Suppression
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Affinity Capture-MS
YCH1 YGR203W Phosphatase with sequence similarity to Mih1p physical 1 1 1 Affinity Capture-MS
YVH1 YIR026C Dual specificity protein phosphatase physical 1 1 1 Affinity Capture-MS
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) physical 1 1 1 Affinity Capture-Western
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex physical 1 1 1 Affinity Capture-MS
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CTF18 YMR078C Subunit of a complex with Ctf8p physical 1 1 1 Affinity Capture-MS
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Phenotypic Enhancement
SGO1 YOR073W Component of the spindle checkpoint physical 1 1 1 Affinity Capture-MS
SGO1 YOR073W Component of the spindle checkpoint genetic 1 1 1 Phenotypic Suppression
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p physical 1 1 1 Affinity Capture-MS
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 1 1 1 Affinity Capture-MS
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein genetic 1 1 1 Dosage Rescue
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 1 1 1 Affinity Capture-MS
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) physical 1 1 1 Affinity Capture-MS
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR physical 1 1 1 Affinity Capture-MS
CDC53 YDL132W Cullin physical 1 1 1 Affinity Capture-MS
RPN2 YIL075C Subunit of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) physical 1 1 1 Affinity Capture-MS
SPO14 YKR031C Phospholipase D physical 1 1 1 Affinity Capture-MS
EMC10 YDR056C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Affinity Capture-MS
KEL1 YHR158C Protein required for proper cell fusion and cell morphology physical 1 1 1 Affinity Capture-MS
NIS1 YNL078W Protein involved in axial bud site selection physical 1 1 1 Affinity Capture-MS
RAD9 YDR217C DNA damage-dependent checkpoint protein physical 1 1 1 Affinity Capture-MS
CNM67 YNL225C Component of the spindle pole body outer plaque physical 1 1 1 Affinity Capture-MS
RSC1 YGR056W Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex physical 1 1 1 Affinity Capture-MS
DCN1 YLR128W Scaffold-type E3 ligase physical 1 1 1 Affinity Capture-MS
RET2 YFR051C Delta subunit of the coatomer complex (COPI) physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
ECM5 YMR176W Subunit of the Snt2C complex physical 1 1 1 Affinity Capture-MS
DMA2 YNL116W Ubiquitin-protein ligase (E3) physical 1 1 1 Affinity Capture-MS
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Phenotypic Suppression
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Affinity Capture-MS
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions physical 1 1 1 Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
PAC2 YER007W Microtubule effector required for tubulin heterodimer formation physical 1 1 1 Affinity Capture-MS
PTC1 YDL006W Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 Affinity Capture-MS
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p physical 1 1 1 Affinity Capture-MS
SOK1 YDR006C Protein of unknown function physical 1 1 1 Affinity Capture-MS
SAL1 YNL083W ADP/ATP transporter physical 1 1 1 Affinity Capture-MS
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) physical 1 1 1 Affinity Capture-MS
DAS1 YJL149W Putative SCF ubiquitin ligase F-box protein physical 1 1 1 Affinity Capture-MS
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
YMR160W YMR160W Protein of unknown function physical 1 1 1 Affinity Capture-MS
MOB1 YIL106W Component of the mitotic exit network physical 1 1 1 Biochemical Activity
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Biochemical Activity
CHS2 YBR038W Chitin synthase II physical 1 1 1 Affinity Capture-Western
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins genetic 1 1 1 Phenotypic Enhancement
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
SMC4 YLR086W Subunit of the condensin complex physical 1 1 1 Biochemical Activity
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Affinity Capture-RNA
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-Western
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Negative Genetic
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Reconstituted Complex
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
YEN1 YER041W Holliday junction resolvase genetic 1 1 1 Phenotypic Enhancement
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
VHS2 YIL135C Regulator of septin dynamics physical 1 1 1 Affinity Capture-Western
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
RPA14 YDR156W RNA polymerase I subunit A14 physical 1 1 1 Affinity Capture-MS
RTG2 YGL252C Sensor of mitochondrial dysfunction physical 1 1 1 Affinity Capture-MS
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Affinity Capture-MS
GLO2 YDR272W Cytoplasmic glyoxalase II physical 1 1 1 Affinity Capture-MS
HIS3 YOR202W Imidazoleglycerol-phosphate dehydratase physical 1 1 1 Affinity Capture-MS
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
NBP1 YLR457C Spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
NCE102 YPR149W Protein of unknown function physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein physical 1 1 1 Affinity Capture-MS
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 1 1 1 Affinity Capture-MS
SRP40 YKR092C Nucleolar serine-rich protein physical 1 1 1 Affinity Capture-MS
OSM1 YJR051W Fumarate reductase, catalyzes the reduction of fumarate to succinate physical 1 1 1 Affinity Capture-MS
ERV46 YAL042W Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-MS
RPL9B YNL067W Ribosomal 60S subunit protein L9B physical 1 1 1 Affinity Capture-MS
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis physical 1 1 1 Affinity Capture-MS
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein physical 1 1 1 Affinity Capture-MS
PUP1 YOR157C Beta 2 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
TIM44 YIL022W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
RPC10 YHR143W-A RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III physical 1 1 1 Affinity Capture-MS
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
RKI1 YOR095C Ribose-5-phosphate ketol-isomerase physical 1 1 1 Affinity Capture-MS
RPA34 YJL148W RNA polymerase I subunit A34.5 physical 1 1 1 Affinity Capture-MS
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Affinity Capture-MS
PIL1 YGR086C Eisosome core component physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 1 1 1 Affinity Capture-Western
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Biochemical Activity
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Synthetic Growth Defect
PDS1 YDR113C Securin genetic 1 1 1 Phenotypic Enhancement
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 1 1 1 Synthetic Rescue
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Synthetic Growth Defect
DPB2 YPR175W Second largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 1 1 1 Synthetic Lethality
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Synthetic Rescue
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 genetic 1 1 1 Synthetic Rescue
MSA1 YOR066W Activator of G1-specific transcription factors MBF and SBF genetic 1 1 1 Synthetic Growth Defect
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Synthetic Growth Defect
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Positive Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
RDL2 YOR286W Protein with rhodanese activity genetic 1 1 1 Positive Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
MYO1 YHR023W Type II myosin heavy chain genetic 1 1 1 Synthetic Growth Defect
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Phenotypic Enhancement
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Dosage Rescue
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Dosage Rescue
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Dosage Rescue
KIP1 YBL063W Kinesin-related motor protein genetic 1 1 1 Phenotypic Suppression
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Phenotypic Suppression
MAM1 YER106W Monopolin genetic 1 1 1 Phenotypic Enhancement
CLB1 YGR108W B-type cyclin involved in cell cycle progression genetic 1 1 1 Phenotypic Enhancement
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 1 1 1 Phenotypic Enhancement
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Phenotypic Enhancement
CLB6 YGR109C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Phenotypic Enhancement
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Dosage Rescue
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Dosage Rescue
NSA2 YER126C Protein constituent of 66S pre-ribosomal particles genetic 1 1 1 Dosage Rescue
CDC33 YOL139C Translation initiation factor eIF4E genetic 1 1 1 Dosage Rescue
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA genetic 1 1 1 Dosage Rescue
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Dosage Rescue
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Dosage Rescue
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation genetic 1 1 1 Dosage Rescue
YLR030W YLR030W Putative protein of unknown function genetic 1 1 1 Dosage Rescue
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 1 1 1 Dosage Rescue
FDO1 YMR144W Protein involved in directionality of mating type switching genetic 1 1 1 Dosage Rescue
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Synthetic Rescue
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Phenotypic Enhancement
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Phenotypic Enhancement
MSN5 YDR335W Karyopherin genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Phenotypic Enhancement
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Positive Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Positive Genetic
SDD4 YPR022C Putative transcription factor, as suggested by computational analysis genetic 1 1 1 Positive Genetic
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex genetic 1 1 1 Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Positive Genetic
COA6 YMR244C-A Protein involved in cytochrome c oxidase (Complex IV) assembly genetic 1 1 1 Positive Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Positive Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Positive Genetic
MIN3 YMR182W-A Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Negative Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
PRP9 YDL030W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Negative Genetic
TAH11 YJR046W DNA replication licensing factor genetic 1 1 1 Negative Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Negative Genetic
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
MCM6 YGL201C Protein involved in DNA replication genetic 1 1 1 Negative Genetic
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
PZF1 YPR186C Transcription factor IIIA (TFIIIA) genetic 1 1 1 Negative Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
ECM15 YBL001C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
PYC2 YBR218C Pyruvate carboxylase isoform genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
SNX41 YDR425W Sorting nexin genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 1 1 1 Negative Genetic
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
PRM6 YML047C Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
IMD4 YML056C Inosine monophosphate dehydrogenase genetic 1 1 1 Negative Genetic
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
PMS1 YNL082W ATP-binding protein required for mismatch repair genetic 1 1 1 Negative Genetic
NRK1 YNL129W Nicotinamide riboside kinase genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II genetic 1 1 1 Negative Genetic
CIT3 YPR001W Dual specificity mitochondrial citrate and methylcitrate synthase genetic 1 1 1 Negative Genetic
MDM36 YPR083W Mitochondrial protein genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
PET112 YBL080C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
MAP2 YBL091C Methionine aminopeptidase genetic 1 1 1 Negative Genetic
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Negative Genetic
YBR137W YBR137W Protein with a role in ER delivery of tail-anchored membrane proteins genetic 1 1 1 Negative Genetic
YBR184W YBR184W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBR196C-A YBR196C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBR242W YBR242W 5'-deoxynucleotidase involved in deoxyribonucleoside monophosphate deg genetic 1 1 1 Negative Genetic
MIC10 YCL057C-A Conserved component of the MICOS complex genetic 1 1 1 Negative Genetic
YDL057W YDL057W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDL211C YDL211C Protein of unknown function genetic 1 1 1 Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
NSI1 YDR026C RNA polymerase I termination factor genetic 1 1 1 Negative Genetic
MFB1 YDR219C Mitochondria-associated F-box protein genetic 1 1 1 Negative Genetic
MGP12 YDR286C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YPQ2 YDR352W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Negative Genetic
UGO1 YDR470C Outer membrane component of the mitochondrial fusion machinery genetic 1 1 1 Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
YER076C YER076C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MRX1 YER077C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Negative Genetic
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Negative Genetic
MRPL25 YGR076C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 1 1 1 Negative Genetic
CTR2 YHR175W Low-affinity copper transporter of the vacuolar membrane genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 1 1 1 Negative Genetic
YIL089W YIL089W Protein of unknown function found in the ER and vacuole lumen genetic 1 1 1 Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Negative Genetic
SNX4 YJL036W Sorting nexin genetic 1 1 1 Negative Genetic
IDS2 YJL146W Protein involved in modulation of Ime2p activity during meiosis genetic 1 1 1 Negative Genetic
SAG1 YJR004C Alpha-agglutinin of alpha-cells genetic 1 1 1 Negative Genetic
THI11 YJR156C Protein involved in synthesis of the thiamine precursor HMP genetic 1 1 1 Negative Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 1 1 1 Negative Genetic
PAU23 YLR037C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
PNP1 YLR209C Purine nucleoside phosphorylase genetic 1 1 1 Negative Genetic
YLR264C-A YLR264C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
HRI1 YLR301W Protein of unknown function that interacts with Sec72p and Hrr25p genetic 1 1 1 Negative Genetic
DPA10 YLR307C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
RPS25B YLR333C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Negative Genetic
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NAB6 YML117W Putative RNA-binding protein genetic 1 1 1 Negative Genetic
YMR001C-A YMR001C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism genetic 1 1 1 Negative Genetic
YMR175W-A YMR175W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
ESBP6 YNL125C Protein with similarity to monocarboxylate permeases genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
RRG9 YNL213C Protein of unknown function genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MET2 YNL277W L-homoserine-O-acetyltransferase genetic 1 1 1 Negative Genetic
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Negative Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 1 1 1 Negative Genetic
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
ISM1 YPL040C Mitochondrial isoleucyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
FEX2 YPL279C Protein involved in fluoride export genetic 1 1 1 Negative Genetic
MSF1 YPR047W Mitochondrial phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein genetic 1 1 1 Phenotypic Enhancement
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
GTO1 YGR154C Omega-class glutathione transferase genetic 1 1 1 Positive Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
SAH1 YER043C S-adenosyl-L-homocysteine hydrolase genetic 1 1 1 Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Phenotypic Enhancement
AVO1 YOL078W Component of the membrane-bound TORC2 complex physical 1 1 1 Affinity Capture-MS
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
ATP3 YBR039W Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
ATP3 YBR039W Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Positive Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism physical 1 1 1 Affinity Capture-MS
APE1 YKL103C Vacuolar aminopeptidase yscI physical 1 1 1 Affinity Capture-MS
AIM46 YHR199C Protein of unknown function genetic 1 1 1 Negative Genetic
CDC123 YLR215C Assembly factor for the eIF2 translation initiation factor complex genetic 1 1 1 Negative Genetic
ATG20 YDL113C Sorting nexin family member physical 1 1 1 Affinity Capture-MS
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Negative Genetic
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase physical 1 1 1 Affinity Capture-MS
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
CBF2 YGR140W Essential kinetochore protein physical 1 1 1 Co-localization
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation genetic 1 1 1 Negative Genetic
BBP1 YPL255W Protein required for the spindle pole body (SPB) duplication physical 1 1 1 Affinity Capture-MS
ALY1 YKR021W Alpha arrestin, substrate of calcineurin physical 1 1 1 Affinity Capture-MS
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
CAT2 YML042W Carnitine acetyl-CoA transferase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
AGC1 YPR021C Mitochondrial amino acid transporter genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Positive Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic