| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
genetic |
7 |
4 |
6 |
Synthetic Lethality, Synthetic Rescue, Synthetic Lethality, Synthetic Rescue, Dosage Rescue, Dosage Rescue, Phenotypic Enhancement |
| TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
genetic |
6 |
3 |
5 |
Dosage Rescue, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
5 |
3 |
5 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
5 |
2 |
5 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Positive Genetic, Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
3 |
2 |
3 |
Positive Genetic, Negative Genetic, Negative Genetic |
| LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Positive Genetic, Positive Genetic |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
physical |
3 |
2 |
3 |
Two-hybrid, Two-hybrid, Affinity Capture-Western |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
3 |
2 |
2 |
Positive Genetic, Phenotypic Suppression, Phenotypic Suppression |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Phenotypic Suppression, Phenotypic Suppression |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Positive Genetic |
| ELO3 |
YLR372W |
Elongase |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue |
| ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| CDC19 |
YAL038W |
Pyruvate kinase |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
| RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
| CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIM11 |
YMR139W |
Protein kinase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| TRM8 |
YDL201W |
Catalytic subunit of a tRNA methyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TSR3 |
YOR006C |
Protein required for 20S pre-rRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRK1 |
YDL079C |
Glycogen synthase kinase 3 (GSK-3) homolog |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AMD1 |
YML035C |
AMP deaminase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CRP1 |
YHR146W |
Protein that binds to cruciform DNA structures |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DBR1 |
YKL149C |
RNA lariat debranching enzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SIL1 |
YOL031C |
Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| ROT2 |
YBR229C |
Glucosidase II catalytic subunit |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SPC2 |
YML055W |
Subunit of signal peptidase complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| SOV1 |
YMR066W |
Mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ALG12 |
YNR030W |
Alpha-1,6-mannosyltransferase localized to the ER |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| CNE1 |
YAL058W |
Calnexin |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| EMP65 |
YER140W |
Integral membrane protein of the ER |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| BMH1 |
YER177W |
14-3-3 protein, major isoform |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YPS3 |
YLR121C |
Aspartic protease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MET3 |
YJR010W |
ATP sulfurylase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GNP1 |
YDR508C |
Broad specificity amino acid permease |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SUN4 |
YNL066W |
Cell wall protein related to glucanases localized in birth scars |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YGP1 |
YNL160W |
Cell wall-related secretory glycoprotein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CIT2 |
YCR005C |
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IRC7 |
YFR055W |
Cysteine desulphydrase, enables growth on cysteine as nitrogen source |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CYC3 |
YAL039C |
Cytochrome c heme lyase (holocytochrome c synthase) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YLR349W |
YLR349W |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YKL153W |
YKL153W |
Dubious open reading frame |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ELO1 |
YJL196C |
Elongase I, medium-chain acyl elongase |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ERR2 |
YPL281C |
Enolase, a phosphopyruvate hydratase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ERR3 |
YMR323W |
Enolase, a phosphopyruvate hydratase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| FRE1 |
YLR214W |
Ferric reductase and cupric reductase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GLK1 |
YCL040W |
Glucokinase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PGI1 |
YBR196C |
Glycolytic enzyme phosphoglucose isomerase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| LCB3 |
YJL134W |
Long-chain base-1-phosphate phosphatase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| HOP2 |
YGL033W |
Meiosis-specific protein that localizes to chromosomes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CIT1 |
YNR001C |
Mitochondrial citrate synthase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FZO1 |
YBR179C |
Mitofusin, protein involved in mitochondrial outer membrane fusion |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| BDH1 |
YAL060W |
NAD-dependent (R,R)-butanediol dehydrogenase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PNC1 |
YGL037C |
Nicotinamidase that converts nicotinamide to nicotinic acid |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GPM2 |
YDL021W |
Nonfunctional homolog of Gpm1p phosphoglycerate mutase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHO11 |
YAR071W |
One of three repressible acid phosphatases |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHO12 |
YHR215W |
One of three repressible acid phosphatases |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHO89 |
YBR296C |
Plasma membrane Na+/Pi cotransporter |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHM7 |
YOL084W |
Protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YCP4 |
YCR004C |
Protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RUP1 |
YOR138C |
Protein that regulates ubiquitination of Rsp5p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YRO2 |
YBR054W |
Protein with a putative role in response to acid stress |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ERR1 |
YOR393W |
Putative phosphopyruvate hydratase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YCL042W |
YCL042W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YGR240C-A |
YGR240C-A |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YLR125W |
YLR125W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YMR206W |
YMR206W |
Putative protein of unknown function |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YGR035C |
YGR035C |
Putative protein of unknown function, potential Cdc28p substrate |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SKS1 |
YPL026C |
Putative serine/threonine protein kinase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PHO5 |
YBR093C |
Repressible acid phosphatase |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YLR410W-A |
YLR410W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YCL020W |
YCL020W |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YDR210W-A |
YDR210W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YFL002W-B |
YFL002W-B |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YGR161W-A |
YGR161W-A |
Retrotransposon TYA Gag gene co-transcribed with TYB Pol |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| WTM1 |
YOR230W |
Transcriptional modulator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Two-hybrid |
| BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BLM10 |
YFL007W |
Proteasome activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
physical |
1 |
1 |
1 |
Two-hybrid |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF20 |
YPR111W |
Ser/Thr kinase involved in late nuclear division |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIM11 |
YMR139W |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAH18 |
YPR048W |
Conserved NAPDH-dependent diflavin reductase |
physical |
1 |
1 |
1 |
Two-hybrid |
| LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Two-hybrid |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
physical |
1 |
1 |
1 |
Two-hybrid |
| RRN11 |
YML043C |
Component of the core factor (CF) rDNA transcription factor complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| PRE5 |
YMR314W |
Alpha 6 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Two-hybrid |
| HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
physical |
1 |
1 |
1 |
Two-hybrid |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD2 |
YKL018W |
Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTA1 |
YAL043C |
Subunit of holo-CPF |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| TVS1 |
YCR061W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1A |
YDL081C |
Ribosomal stalk protein P1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR008C-A |
YOR008C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HTB1 |
YDR224C |
Histone H2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HIS3 |
YOR202W |
Imidazoleglycerol-phosphate dehydratase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAL33 |
YBR297W |
MAL-activator protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LYS14 |
YDR034C |
Transcriptional activator involved in regulating lysine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUT2 |
YPR009W |
Zn2Cys6 family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET31 |
YPL038W |
Zinc-finger DNA-binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR3 |
YBL005W |
Transcriptional activator of the pleiotropic drug resistance network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPP1 |
YPL138C |
Subunit of COMPASS (Set1C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKO1 |
YNL167C |
Basic leucine zipper transcription factor of the ATF/CREB family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAP3 |
YHL009C |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIP3 |
YNL257C |
Putative sterol transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPC2 |
YDR213W |
Sterol regulatory element binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PKH1 |
YDR490C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAL9 |
YOL089C |
Putative transcription factor containing a zinc finger |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRK1 |
YOR267C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KCC4 |
YCL024W |
Protein kinase of the bud neck involved in the septin checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK31 |
YCR020C-A |
Non-catalytic subunit of N-terminal acetyltransferase of the NatC type |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMS2 |
YGL087C |
Ubiquitin-conjugating enzyme variant |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL070C |
YJL070C |
Putative metallo-dependent hydrolase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP53 |
YPL146C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSR2 |
YLR019W |
Putative plasma membrane phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IDP2 |
YLR174W |
Cytosolic NADP-specific isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YNK1 |
YKL067W |
Nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSH6 |
YDR097C |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NIT2 |
YJL126W |
Nit protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEL1 |
YBL088C |
Protein kinase primarily involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT1 |
YLR142W |
Proline oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ESL1 |
YIL151C |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNR1 |
YIL159W |
Formin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DAL80 |
YKR034W |
Negative regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASG1 |
YIL130W |
Zinc cluster protein proposed to be a transcriptional regulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDA2 |
YLR308W |
Chitin deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |